In the roots of plants, the H+/K+ symporters are only one member of a group of several symporters/antiporters that specifically ... like H+/K+ symporters allow the specific ions to come into the cell and the out the plasmodesmata/symporters/antiporters of the ... Na+/K+/2Cl− symporter in the loop of Henle in the renal tubules of the kidney transports 4 molecules of 3 different types; a ... A symporter is an integral membrane protein that is involved in the transport of two (or more) different molecules across the ...
H+ symporter of Bacillus subtillus (GntP; TC# 2.A.8.1.1) and the D-fructuronate/D-gluconate:H+ symporter of E. coli (GntP; TC# ... The gluconate:H+ symporter (GntP) family (TC# 2.A.8) is a family of transport proteins belonging to the ion transporter (IT) ... The original text was at "The Gluconate:H+ Symporter (GntP) Family" v t e (Protein pages needing a picture, Articles with ... "2.A.8 The Gluconate:H+ Symporter (GntP) Family". Transporter Classification Database. Retrieved 2016-03-04. Porco A, Peekhaus N ...
One of these families is known as the sodium:dicarboxylate symporter family (SDF) (it is different from divalent anion-sodium ... Reizer J, Reizer A, Saier MH (June 1994). "A functional superfamily of sodium/solute symporters". Biochim. Biophys. Acta. 1197 ... sodium symporters) can be grouped, on the basis of sequence and functional similarities into a number of distinct families. ... symporter). Such re-uptake of neurotransmitters from the synapses, is thought to be an important mechanism for terminating ...
A neurotransmitter sodium symporter (NSS) (TC# 2.A.22) is type of neurotransmitter transporter that catalyzes the uptake of a ... Neurotransmitter sodium symporters (NSS) are targets for anti-depressants, psychostimulants and other drugs. The generalized ... "2.A.22 The Neurotransmitter:Sodium Symporter (NSS) Family". Transporter Classification Database. Attwell D, Bouvier M (1992). " ... 2 Na+ symporter, LeuTAa: 2A65​, 2Q6H​, 2Q72​, 2QB4​, 2QJU​, 3F3A​, 3F3C​, (more) Several characterized proteins are classified ...
Sodium+Chloride+Symporters at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Sodium+Chloride+Symporter+ ... The sodium-chloride symporter accounts for the absorption of 5% of the salt filtered at the glomerulus. NCC activity is known ... The sodium-chloride symporter (also known as Na+-Cl− cotransporter, NCC or NCCT, or as the thiazide-sensitive Na+-Cl− ... The sodium-chloride symporter or NCC is a member of the SLC12 cotransporter family of electroneutral cation-coupled chloride ...
These sodium symporters can be grouped, on the basis of sequence and functional similarities into a number of distinct families ... Sodium sulfate symporters are integral membrane proteins that mediate the intake of a wide variety of molecules with the ... This family also includes a number of bacterial symporters. Markovich D, Forgo J, Stange G, Biber J, Murer H (September 1993 ...
The benzoate:H symporter (BenE) family (TC# 2.A.46) is a member of the APC Superfamily. The BenE family contains only two ... "2.A.46 The Benzoate:H Symporter (BenE) Family". Transporter Classification Database. Saier Lab Bioinformatics Group @ UCSD / ... H Symporter (AAHS) family (TC# 2.A.1.15) of the Major Facilitator Superfamily (MFS). The degree of similarity with the latter ...
The Malonate:Na+ Symporter (MSS) Family (TC# 2.A.70) is a group of transport proteins belonging to the CPA superfamily. These ... As of this edit, this article uses content from "2.A.70 The Malonate:Na+ Symporter (MSS) Family", which is licensed in a way ... "Malonate/sodium symporter MadM subunit, N-terminal (IPR018402) < InterPro < EMBL-EBI". www.ebi.ac.uk. Retrieved 2016-04-06. ... One constituent member of the MSS family, the monobasic malonate:Na+ symporter of Malonomonas rubra, has been functionally and ...
... are classified into: Chloride potassium symporter 4, predominating in the kidney. Chloride ... For example, chloride potassium symporter 5, or KCC2, is expressed through the SLC12A5 gene. Notably, symporters prior to 4 in ... The chloride potassium symporter is a membrane transport protein of the solute carrier family 12 that is present in the S3- ... Chloride potassium symporter can lower intracellular chloride concentrations below the electrochemical equilibrium potential. ...
Sodium/pantothenate symporter InterPro: IPR011849 Sodium/proline symporter InterPro: IPR011851 Cation/acetate symporter ActP ... of Escherichia coli is homologous to the Na+/proline symporter (PutP) of E. coli and the Na+/glucose symporters of mammals". ... Members of the Solute:Sodium Symporter (SSS) Family (TC# 2.A.21) catalyze solute:Na+ symport. The SSS family is within the APC ... The human placental multivitamin symporter co-transports an anionic vitamin with two Na+. In the rabbit Na+:D-glucose co- ...
Potassium-chloride transporter, member 4 is a chloride potassium symporter protein. It is encoded by the gene SLC12A4. Solute ...
This family of proteins are found both in prokaryotes and eukaryotes. In mammals, they are transmembrane proteins with functions in the liver and in the intestine. They are members of the solute carrier family of cotransporter genes which include SLC10A1 and SLC10A2. SLC10A1 encodes the sodium-taurocholate cotransporting polypeptide (NTCP) expressed in the liver and found on the basolateral membranes. It is involved in the uptake of all types of bile acids from portal blood plasma, a process mediated by the co-transport of Na+. It is also capable of transporting other solutes and is necessary for the entry of hepatitis B and hepatitis D viruses into the hepatocyte. SLC10A2 encodes the apical sodium bile acid transporter (ASBT) expressed in the small intestine with highest concentrations in the ileum. It is found on the brush border membrane and is also known as the ileal bile acid transporter (IBAT). It is responsible for the initial uptake of bile acids from the intestine as part of the ...
Both KCC2 isoforms can form homomultimers, or heteromultimers with other K-Cl symporters on the cell membrane to maintain ... Potassium-chloride transporter member 5 (aka: KCC2 and SLC12A5) is a neuron-specific chloride potassium symporter responsible ... symporter that maintains chloride homeostasis in neurons. The electrochemical chloride gradient established by KCC2 activity is ...
The Nucleobase:Cation Symporter-1 (NCS1) Family (TC# 2.A.39) consists of over 1000 currently sequenced proteins derived from ... NCS1 proteins are H+/Na+ symporters specific for the uptake of purines, pyrimidines and related metabolites. Krypotou et al. ... In these respects, and with respect to substrate specificity, these proteins resemble the symporters of the NCS2 family, ... "2.A.39 The Nucleobase:Cation Symporter-1 (NCS1) Family". Transporter Classification Database. Saier Lab Bioinformatics Group / ...
Divalent anion:Na+ symporters were found in bacteria, archaea, plant chloroplasts and animals. They vary in size from 432 amino ... They are all Na+-coupled symporters. The Na+:anion coupling ratio is 3:1, indicative of electrogenic properties. They have a ...
The Nucleobase cation symporter-2 (NCS2) family, also called the Nucleobase ascorbate transporter (NAT) family, consists of ... "2.A.40 The Nucleobase/Ascorbate Transporter (NAT) or Nucleobase:Cation Symporter-2 (NCS2) Family". Transporter Classification ...
H+ symporter of Schizosaccharomyces pombe. This yeast protein is about 24% identical to the plant sucrose:H+ symporters and is ... The generalized transport reaction catalyzed by the GPH:cation symporter family is: Sugar (out) + [H+ or Na+] (out) → Sugar (in ... As of this edit, this article uses content from "2.A.2 The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family", which ... Homologues are from bacteria, including the distantly related sucrose:H+ symporters of plants and a yeast maltose/sucrose: ...
The branched chain amino acid:cation symporter (LIVCS) family (TC# 2.A.26) is a member of the APC superfamily. Characterized ... "2.A.26 The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family". Transporter Classification Database. Braun, Peter R.; Al ... June 29, 1994). "A functional superfamily of sodium/solute symporters.". 1197(2): (2): 133-66. PMID 8031825. Portal: Biology v ...
Measles virus encoding the human thyroidal sodium iodide symporter or MV-NIS is an attenuated oncolytic Edmonston (Ed) strain ... guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter ... Imaging and Radiovirotherapy of Prostate Cancer Using an Oncolytic Measles Virus Expressing the Sodium Iodide Symporter". ... Measles Virus Administered With or Without Cyclophosphamide Oncolytic measles virus encoding thyroidal sodium iodide symporter ...
Antiporter Symporter Cammack, Richard; Atwood, Teresa; Campbell, Peter; Parish, Howard; Smith, Anthony; Vella, Frank; Stirling ... Wolfersberger, MG (November 1994). "Uniporters, Symporters and Antiporters". J Exp Biol. 196: 5-6. doi:10.1242/jeb.196.1.5. ...
The SGLT1 protein is a symporter system because it passes both glucose and sodium in the same direction, from the lumen of the ... An example of a symporter mediated transport protein is SGLT1, a sodium/glucose co-transporter protein that is mainly found in ... WOLFERSBERGER, MICHAEL (1994). "Uniporters, symporters and antiporters" (PDF). Journal of Experimental Biology. 196: 5-6. doi: ...
Both Indy proteins are sodium sulfate symporters. Its name originates from a well-known comic line in Monty Python and the Holy ...
This symporter is located in the small intestines, heart, and brain. It is also located in the S3 segment of the proximal ... A symporter uses the downhill movement of one solute species from high to low concentration to move another molecule uphill ... In a symporter, two substrates are transported in the same direction across the membrane. Antiport and symport processes are ... An example is the glucose symporter SGLT1, which co-transports one glucose (or galactose) molecule into the cell for every two ...
2.A: Porters (uniporters, symporters, antiporters), SLCs. Excitatory amino acid transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 ...
Na+/I− symporter (NIS) - Sodium-Iodide is a type of symporter that is responsible for transferring iodide in the thyroid gland ... K+Cl− Symporter - The K+-Cl− cotransporter family consists of four specific symporters known as KCC1, KCC2, KCC3, and KCC4. The ... Antiporters and symporters both transport two or more different types of molecules at the same time in a coupled movement. An ... Na-K-2Cl symporter - This specific cotransporter regulates the cell volume by controlling the water and electrolyte content ...
Sodium Symporters (NSS). One of these proteins, LeuT, from Aquifex aeolicus, was crystallized by Yamashita et al. with very ... sodium symporters". Nature Structural & Molecular Biology. 17 (7): 822-9. doi:10.1038/nsmb.1854. PMC 3245867. PMID 20562855. ... sodium symporters". Nature. 449 (7163): 726-30. Bibcode:2007Natur.449..726Z. doi:10.1038/nature06133. PMID 17704762. S2CID ...
"Sodium-dependent lysophosphatidylcholine symporter 1". UniProt. Retrieved 2 April 2016. Ben-Zvi A, Lacoste B, Kur E, Andreone ... also known as sodium-dependent lysophosphatidylcholine symporter 1 -- is a protein that in humans is encoded by the MFSD2A gene ...
"Sodium-dependent lysophosphatidylcholine symporter 1". UniProt. Archived from the original on 22 April 2019. Retrieved 2 April ...
Both SLC25A22 and SLC25A18 are mitochondrial glutamate/H+ symporters. Mutations in the SLC25A22 gene cause early infantile ...
Na+ Symporter (PNaS) Family 2.A.82 - The Organic Solute Transporter (OST) Family 2.A.102 - The 4-Toluene Sulfonate Uptake ... Na+ symporters (PNaS); TC# 2.A.58) and (9) lysosomal cystine transporters (LCT); TC# 2.A.43). Currently recognized families ...