Serine
D-Serine, synthesized in neurons by serine racemase from L-serine (its enantiomer), serves as a neuromodulator by coactivating ... Serine hydroxymethyltransferase (SHMT = serine transhydroxymethylase) also catalyzes the reversible conversions of L-serine to ... Pure D-serine is an off-white crystalline powder with a very faint musty aroma. D-Serine is sweet with an additional minor sour ... D-Serine is being studied in rodents as a potential treatment for schizophrenia. D-Serine also has been described as a ...
Serine racemase
This enzyme converts L-serine to its enantiomer form, D-serine. D-serine acts as a neuronal signaling molecule by activating ... In humans, the serine racemase protein is encoded by the SRR gene. Serine racemase may have evolved from L-thre- ... Mammalian serine racemase is a pyridoxal 5'-phosphate dependent enzyme that catalyzes both the racemization of L-serine to D- ... serine and also the elimination of water from L-serine, generating pyruvate and ammonia through the β-elimination of L-serine. ...
Serine hydroxymethyltransferase
Once the serine is bonded to PLP, PLP triggers the α-elimination of the hydroxymethyl group of the substrate (serine). This ... Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP) (Vitamin B6) dependent enzyme (EC 2.1.2.1) which plays an ... However, THF is not an obligate substrate for SHMT, meaning the cleavage of serine and other β-hydroxy amino acids (such as ... Serine+Hydroxymethyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC ...
Serine hydrolase
Unlike other, non-catalytic, serines, the reactive serine of these hydrolases is typically activated by a proton relay ... Superfamilies of serine hydrolases includes: Serine proteases, including trypsin, chymotrypsin, and subtilisin Extracellular ... Serine hydrolases are one of the largest known enzyme classes comprising approximately ~200 enzymes or 1% of the genes in the ... A defining characteristic of these enzymes is the presence of a particular serine at the active site, which is used for the ...
Serine dehydratase
L-serine ammonia-lyase Serine deaminase L-hydroxyaminoacid dehydratase L-serine deaminase L-serine dehydratase L-serine hydro- ... Serine dehydratase or L-serine ammonia lyase (SDH) is in the β-family of pyridoxal phosphate-dependent (PLP) enzymes. SDH is ... Rowsell EV, Carnie JA, Wahbi SD, Al-Tai AH, Rowsell KV (1979). "L-serine dehydratase and L-serine-pyruvate aminotransferase ... Glycine can be converted into serine and either become pyruvate via serine dehydratase or undergo oxidative cleavage into ...
Serine protease
... s (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the ... Serine Peptidase Serine Proteases site at Saint Louis University (SLU) Serine+proteases at the U.S. National Library of ... The serine -OH attacks the carbonyl carbon, and the nitrogen of the histidine accepts the hydrogen from the -OH of the [serine ... Serine proteases are paired with serine protease inhibitors, which turn off their activity when they are no longer needed.[self ...
Serine O-acetyltransferase
Other names in common use include SATase, L-serine acetyltransferase, serine acetyltransferase, and serine transacetylase. This ... Smith IK, Thompson JF (1971). "Purification and characterization of L-serine transacetylase and O-acetyl-L-serine sulfhydrylase ... O-acetyl-L-serine Thus, the two substrates of this enzyme are acetyl-CoA and L-serine, whereas its two products are CoA and O- ... In enzymology, a serine O-acetyltransferase (EC 2.3.1.30) is an enzyme that catalyzes the chemical reaction acetyl-CoA + L- ...
Serine (data page)
a 200-274-3 EINECS for Serine ^a CID 617 from PubChem ^a CID 5951 from PubChem (Articles with short description, Short ...
Serine C-palmitoyltransferase
... serine palmitoyltransferase, SPT, 3-oxosphinganine synthetase, and acyl-CoA:serine C-2 acyltransferase decarboxylating. Serine ... Serine C-palmitoyltransferase is expressed in a large number of species from bacteria to humans. The bacterial enzyme is a ... In enzymology, a serine C-palmitoyltransferase (EC 2.3.1.50) is an enzyme that catalyzes the chemical reaction: palmitoyl-CoA ... Gable K, Slife H, Bacikova D, Monaghan E, Dunn TM (March 2000). "Tsc3p is an 80-amino acid protein associated with serine ...
Serine 2-dehydrogenase
In enzymology, a serine 2-dehydrogenase (EC 1.4.1.7) is an enzyme that catalyzes the chemical reaction L-serine + H2O + NAD+ ... Other names in common use include L-serine:NAD+ oxidoreductase (deaminating), and serine dehydrogenase. Kretovich VL, ... The systematic name of this enzyme class is L-serine:NAD+ 2-oxidoreductase (deaminating). ... displaystyle \rightleftharpoons } 3-hydroxypyruvate + NH3 + NADH + H+ The 3 substrates of this enzyme are L-serine, H2O, and ...
L-serine dehydratase
... may refer to: Serine dehydratase, an enzyme Threonine ammonia-lyase, an enzyme This set index page lists ...
Serine 3-dehydrogenase
In enzymology, a serine 3-dehydrogenase (EC 1.1.1.276) is an enzyme that catalyzes the chemical reaction L-serine + NADP+ ⇌ {\ ... The systematic name of this enzyme class is L-serine:NADP+ 3-oxidoreductase. Fujisawa H, Nagata S, Chowdhury EK, Matsumoto M, ... Chowdhury EK, Higuchi K, Nagata S, Misono H (1997). "A novel NADP(+)-dependent serine dehydrogenase from Agrobacterium ... the two substrates of this enzyme are L-serine and NADP+, whereas its 3 products are 2-ammoniomalonate semialdehyde, NADPH, and ...
Serine-pyruvate transaminase
In enzymology, a serine-pyruvate transaminase (EC 2.6.1.51) is an enzyme that catalyzes the chemical reaction L-serine + ... The systematic name of this enzyme class is L-serine:pyruvate aminotransferase. Other names in common use include SPT, and ... Sallach HJ (1956). "Formation of serine from hydroxypyruvate and L-alanine". J. Biol. Chem. 223: 1101-1108. Portal: Biology v t ... This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate. As of late ...
Serine-tRNA ligase
In enzymology, a serine-tRNA ligase (EC 6.1.1.11) is an enzyme that catalyzes the chemical reaction ATP + L-serine + tRNASer ... and serine translase. This enzyme participates in glycine, serine and threonine metabolism and aminoacyl-trna biosynthesis. As ... The systematic name of this enzyme class is L-serine:tRNASer ligase (AMP-forming). Other names in common use include seryl-tRNA ... Ohama T, Yang DC, Hatfield DL (1994). "Selenocysteine tRNA and serine tRNA are aminoacylated by the same synthetase, but may ...
Serine-phosphoethanolamine synthase
Other names in common use include serine ethanolamine phosphate synthetase, serine ethanolamine phosphodiester synthase, serine ... L-serine-phosphoethanolamine Thus, the two substrates of this enzyme are CDP-ethanolamine and L-serine, whereas its two ... In enzymology, a serine-phosphoethanolamine synthase (EC 2.7.8.4) is an enzyme that catalyzes the chemical reaction CDP- ... Allen AK, Rosenberg H (1968). "The mechanism of action and some properties of serine ethanolamine phosphate synthetase". ...
Serine-ethanolaminephosphate phosphodiesterase
The enzyme serine-ethanolaminephosphate phosphodiesterase (EC 3.1.4.13) catalyzes the reaction serine phosphoethanolamine + H2O ... The systematic name is serine-phosphoethanolamine ethanolaminephosphohydrolase. Other names in common use include serine ... Hagerman DD, Rosenberg H, Ennor AH, Schiff P, Inoue S (1965). "The isolation and properties of chicken kidney serine ... displaystyle \rightleftharpoons } serine + ethanolamine phosphate This enzyme belongs to the family of hydrolases, specifically ...
Serine octamer cluster
The Serine octamer cluster in physical chemistry is an unusually stable cluster consisting of eight serine molecules (Ser) ... A racemic serine solution produces a minimum amount of cluster and with solutions of both enantiomers a maximum amount is ... The same octamer ions are also produced by rapid evaporation of a serine solution on a hot (200-250 °C) metal surface or by ... A cycle can be maintained in which each turn results in an incremental enrichment in L-serine. Many such cycles eventually ...
Diphosphate-serine phosphotransferase
Other names in common use include pyrophosphate-serine phosphotransferase, and pyrophosphate-L-serine phosphotransferase. Cagen ... O-phospho-L-serine Thus, the two substrates of this enzyme are diphosphate and L-serine, whereas its two products are phosphate ... In enzymology, a diphosphate-serine phosphotransferase (EC 2.7.1.80) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is diphosphate:L-serine O-phosphotransferase. ...
Serine hydroxymethyltransferase 2
... is an enzyme that in humans is encoded by the SHMT2 gene. GRCh38: Ensembl release 89: ...
Protein-serine epimerase
D-serine Hence, this enzyme has one substrate, [protein]-L-serine, and one product, [protein]-D-serine. This enzyme belongs to ... The systematic name of this enzyme class is [protein]-serine epimerase. This enzyme is also called protein-serine racemase. As ... In enzymology, a protein-serine epimerase (EC 5.1.1.16) is an enzyme that catalyzes the chemical reaction [protein]-L-serine ...
Serine protease 57
... is a protein that in humans is encoded by the PRSS57 gene. This gene encodes an arginine-specific serine ... "Entrez Gene: Serine protease 57". Retrieved 2018-08-19. Perera NC, Wiesmüller KH, Larsen MT, Schacher B, Eickholz P, Borregaard ...
Serine-glyoxylate transaminase
In enzymology, a serine-glyoxylate transaminase (EC 2.6.1.45) is an enzyme that catalyzes the chemical reaction L-serine + ... The systematic name of this enzyme class is L-serine:glyoxylate aminotransferase. This enzyme participates in glycine, serine ... Smith IK (1973). "Purification and characterization of serine:glyoxylate aminotransferase from kidney bean (Phaseolus vulgaris ... the two substrates of this enzyme are L-serine and glyoxylate, whereas its two products are 3-hydroxypyruvate and glycine. This ...
L-serine-phosphatidylethanolamine phosphatidyltransferase
... (EC 2.7.8.29, phosphatidylserine synthase 2, serine-exchange enzyme ... L-serine-phosphatidylethanolamine+phosphatidyltransferase at the U.S. National Library of Medicine Medical Subject Headings ( ... This enzyme catalyses the following chemical reaction L-1-phosphatidylethanolamine + L-serine ⇌ {\displaystyle \ ... ethanolamine This enzyme catalyses replacement of a polar head group of phosphatidylethanolamine with L-serine. Stone SJ, Vance ...
IgA specific serine endopeptidase
... where the X in the sequence preferably is a Proline or Serine; the Y = Threonine, Serine or Alanine; and Z preferably is ... IgA-specific+serine+endopeptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology ( ... IgA protease (EC 3.4.21.72, IgA-specific serine endopeptidase, IgA proteinase, IgA-specific proteinase, immunoglobulin A ...
Equine arterivirus serine peptidase
Equine+arterivirus+serine+peptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology v ... Equine arterivirus serine peptidase (EC 3.4.21.114) is an enzyme. This enzyme catalyses the following chemical reaction ... the 3C-like serine proteases". The Journal of Biological Chemistry. 271 (9): 4864-71. doi:10.1074/jbc.271.9.4864. PMID 8617757 ... "Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease ...
D-serine ammonia-lyase
D-serine hydrolase, D-serine dehydratase (deaminating), D-serine deaminase, and D-serine hydro-lyase (deaminating). This enzyme ... The enzyme D-serine ammonia-lyase (EC 4.3.1.18), with systematic name D-serine ammonia-lyase (pyruvate-forming), catalyzes the ... METZLER DE, SNELL EE (1952). "Deamination of serine. II. D-Serine dehydrase, a vitamin B6 enzyme from Escherichia coli". J. ... Dupourque D, Newton WA, Snell EE (1966). "Purification and properties of D-serine dehydrase from Escherichia coli". J. Biol. ...
HtrA serine peptidase 2
Protein HtrA2, also known as Omi, is a mitochondrially-located serine protease. The human protein Serine protease HTRA2, ... Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene. This protein is involved in ... HtrA serine peptidase 2 has been shown to interact with MAPK14, XIAP and BIRC2. GRCh38: Ensembl release 89: ENSG00000115317 - ... "Entrez Gene: HTRA2 HtrA serine peptidase 2". Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnóczky G, ...
Serine-sulfate ammonia-lyase
The enzyme Serine-sulfate ammonia-lyase (EC 4.3.1.10) catalyzes the chemical reaction L-serine O-sulfate + H2O ⇌ {\displaystyle ... The systematic name of this enzyme class is L-serine-O-sulfate ammonia-lyase (pyruvate-forming). It is also called (L-SOS)lyase ... Thomas JH, Tudball N (1967). "Studies on the enzymic degradation of L-serine O-sulphate by a rat liver preparation". Biochem. J ...
L-serine ammonia-lyase
L-serine deaminase, L-serine dehydratase, and L-serine hydro-lyase (deaminating). This enzyme participates in glycine, serine, ... The enzyme L-serine ammonia-lyase (EC 4.3.1.17) catalyzes the chemical reaction L-serine = pyruvate + NH3 (overall reaction) ( ... The systematic name of this enzyme class is L-serine ammonia-lyase (pyruvate-forming). Other names in common use include serine ... Ramos F, Wiame JM (1982). "Occurrence of a catabolic L-serine (L-threonine) deaminase in Saccharomyces cerevisiae". Eur. J. ...
Carbamoyl-serine ammonia-lyase
The enzyme carbamoyl-serine ammonia-lyase (EC 4.3.1.13) catalyzes the chemical reaction O-carbamoyl-L-serine + H2O = pyruvate ... Other names in common use include O-carbamoyl-L-serine deaminase, carbamoylserine deaminase, and O-carbamoyl-L-serine ammonia- ... Copper AJ, Meister A (1973). "Enzymatic conversion of O-carbamyl-L-serine to pyruvate and ammonia". Biochem. Biophys. Res. ... The systematic name of this enzyme class is O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming). ...