Two other well known examples are CD34 and GLYCAM-1. B lymphocyte T lymphocyte Lymphocyte+homing+receptors at the U.S. National ... Lymphocyte homing receptors are cell adhesion molecules expressed on lymphocyte cell membranes that recognize addressins on ... Lymphocyte homing receptor control of organ-specific lymphocyte trafficking is thought to prevent autoreactivity in immune ... Lymphocyte homing receptor expression is altered by antigen exposure. This function enables the adaptive immune system to ...

It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family of ... "Entrez Gene: ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)". Hadari YR, Arbel-Goren R, Levy Y, ... Rosemblatt M, Vuillet-Gaugler MH, Leroy C, Coulombel L (1991). "Coexpression of two fibronectin receptors, VLA-4 and VLA-5, by ... Porter JC, Hogg N (1999). "Integrins take partners: cross-talk between integrins and other membrane receptors". Trends Cell ...

"Homing Receptors and Vascular Addressins: Cell Adhesion Molecules that Direct Lymphocyte Traffic". Immunological Reviews. 108 ( ... One of the CAMS that are particularly important in the lymphocyte homing is addressin. Lymphocyte homing is a key process ... Gorfu G, Rivera-Nieves J, Ley K (September 2009). "Role of beta7 integrins in intestinal lymphocyte homing and retention". Curr ... Picker, Louis (1 June 1994). "Control of lymphocyte homing". Current Opinion in Immunology. 6 (3): 394-406. doi:10.1016/0952- ...

... "homing receptor" for lymphocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on ... Homology with the mouse lymphocyte homing receptor and other human adhesion proteins". The Journal of Experimental Medicine. ... The receptor is commonly found on the cell surfaces of T cells. Naive T-lymphocytes, which have not yet encountered their ... Similar to its function in lymphocytes, L-selectin acts as a receptor to facilitate adhesion of the embryo to the site of ...

"Homing receptors" are crucial in forming in the interactions which allow lymphocyte movement. MadCAM-1 expression is continuous ... The mechanism of gut specific homing is one largely based on interactions between receptors. Lymphocytes migrate from the blood ... B cell homing- There is limited knowledge of this as of late. Mackay (1993). "Homing of naive, memory and effector lymphocytes ... Gut specific homing is the most understood of lymphocyte homing. However, there are many other examples which include: Lymphoid ...

... s are the ligands to the homing receptors of lymphocytes. The task of these ligands and their receptors is to ... Peripheral node addressins (PNAd) are carbohydrate residues that are lymphocyte homing receptor ligands that are expressed on ... Picker LJ, Butcher EC (1992-04-01). "Physiological and molecular mechanisms of lymphocyte homing". Annual Review of Immunology ... Addressin is a lesser-used term to describe the group of adhesion molecules that are involved with lymphocyte homing, commonly ...

"Identification of a soluble form of a ligand for the lymphocyte homing receptor". The Journal of Experimental Medicine. 176 (5 ... It is the ligand for the receptor L-selectin allowing for naive lymphocytes to exit the bloodstream into lymphoid tissues. ...

The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important ... Townson JR, Nibbs RJ (2002). "Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/ ... receptors mediates transendothelial migration of T lymphocytes across lymph node high endothelial cells". Eur. J. Immunol. 32 ( ... This chemokine elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7. It ...

"Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon". The ... The cell surface receptor binding region of Interferon-γ overlaps with the HS binding region, near the protein's C-terminal. ... HS has also been shown to serve as cellular receptor for a number of viruses, including the respiratory syncytial virus. One ... Binding of HS blocks the receptor binding site and as a result, protein-HS complexes are inactive. Glypican-3 (GPC3) interacts ...

"Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase". ... Kingsley DM, Kozarsky KF, Hobbie L, Krieger M (March 1986). "Reversible defects in O-linked glycosylation and LDL receptor ... "Role of the membrane-proximal O-glycosylation site in sorting of the human receptor for neurotrophins to the apical membrane of ...

2001). "Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N- ... lymphocyte homing and lymphocyte trafficking. GRCh38: Ensembl release 89: ENSG00000179913 - Ensembl, May 2017 GRCm38: Ensembl ...

2001). "Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N- ...

STAB1 is a large transmembrane receptor protein which may function in many aspects such as lymphocyte homing or angiogenesis. ... "HomoloGene Home". Ncbi.nlm.nih.gov. Retrieved 2013-07-26. "BLAST: Basic Local Alignment Search Tool". Blast.ncbi.nlm.nih.gov. ... "Home - GEO Profiles - NCBI". Ncbi.nlm.nih.gov. 2013-03-25. Retrieved 2013-07-26. Q9BWS9 (Articles with short description, Short ...

... is a homing receptor that mediates rolling and firm adhesion of lymphocytes to endothelial cells. Subsequently this ... This receptor is involved in lymphocyte trafficking pathway to site of inflammation in intestinal tissues. LPAM-1 α and β ... Several monoclonal antibodies have been developed in order to block this interaction and inhibit lymphocytes homing from blood ... "Role of beta7 integrins in intestinal lymphocyte homing and retention". Current Molecular Medicine. 9 (7): 836-850. doi:10.2174 ...

On the other hand, they have lower expression of S1P receptor S1PR1, homing receptor to lymph node CD62L, activation marker ... Skin TRM: TRM cells in the skin express cutaneous lymphocyte antigen (CLA) and CCR8 which are skin homing antigens. They have ... CD8+ T lymphocytes destroy melanocytes in some parts of the skin what manifest like white spots on the skin. Multiple genes as ... Cytotoxic CD8+ T lymphocytes are able to recognize malignant cells. Production of neoantigens by tumour cells can lead to ...

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion ... 2003). "The same endothelial receptor controls lymphocyte traffic both in vascular and lymphatic vessels". Eur. J. Immunol. 33 ... plasma membrane-endosomal trafficking of the lymph node sinus and high endothelial venule scavenger receptor/homing receptor ... The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, ...

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion ... The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram- ... Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and ... Adachi H, Tsujimoto M (September 2002). "FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis- ...

... of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes". ... Resting T- and B-lymphocytes lack its expression and are induced to strongly express sialyl Lewis X upon activation. The sialyl ... receptor was found to be the preferred binding site, both in humans and in dromedary camels, for the coronavirus causing Middle ... "Structural basis for human coronavirus attachment to sialic acid receptors". Nature Structural & Molecular Biology. 26 (6): 481 ...

The chemokine receptor CXCR5 is expressed on B cells and CD4+ Tfh cells and is involved in lymphocyte homing and the ... CXCR3 is expressed predominantly on T cells (T lymphocytes), and also on other lymphocytes [some B cells (B lymphocytes) and NK ... ACKR3 was originally called RDC-1 (an orphan receptor) but has since been shown to cause chemotaxis in T lymphocytes in ... "Chemokine Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. ( ...

CCL27 is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the ... April 2000). "Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated ... The gene for CCL27 is located on human chromosome 9. Studies of a similar murine protein indicate that these protein-receptor ... CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells. Proc. Natl. Acad. Sci. U.S.A. 96: ...

... lymphocyte homing receptor, ECM-III, and HUTCH-1. CD44 is expressed in a large number of mammalian cell types. The standard ... HCELL functions as a "bone homing receptor", directing migration of human hematopoietic stem cells and mesenchymal stem cells ... CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, ... CD44 is a receptor for hyaluronic acid and internalizes metals bound to hyaluronic acid and can also interact with other ...

... and platelet-derived growth factor receptor (PGDFR). Th22 cells differentiate from naive T-lymphocytes in presence of number of ... CCR4 that are associated with cutaneous T cell homing, ... and binds to the IL-23 receptor of skin dendritic cells. This ... CCR5 and α4β7 molecules expressed by Th22 cells were able to bind to the circulating HIV receptor, and thus via interleukin-22 ... Additionally, they could be characterized by their cell surface expression of CD3, CD4, CD28, number of chemokine receptors ...

It is also produced by dendritic cells and attracts also naive T lymphocytes and B lymphocytes to homing into the lymph node, ... MIP-3α (CCL20) and MIP-3β (CCL19). MIP-3α is binding to receptor CCR6. CCL20 is produced by mucosa and skin by activated ... Polymerization buries receptor-binding sites of MIP-1, thus depolymerization mutations enhance MIP-1 to arrest monocytes onto ... Mature dendritic cells down-regulate CCR6 and up-regulate CCR7, which is receptor for MIP-3β. MIP-3β (CCL19) is produced by ...

... receptors, lymphocyte homing MeSH D12.776.395.550.200.625.144 - antigens, cd44 MeSH D12.776.395.550.200.625.347 - integrin ... receptor, par-1 MeSH D12.776.395.550.625.800.800 - thrombomodulin MeSH D12.776.395.550.625.905 - p-selectin MeSH D12.776. ... receptors, thrombin MeSH D12.776.395.550.625.800.780 - platelet glycoprotein gpib-ix complex MeSH D12.776.395.550.625.800.790 ... alpha4beta1 MeSH D12.776.395.550.200.625.550 - lymphocyte function-associated antigen-1 MeSH D12.776.395.550.200.625.903 - l- ...

... receptors, lymphocyte homing MeSH D12.776.543.550.200.625.144 - antigens, cd44 MeSH D12.776.543.550.200.625.347 - integrin ... receptor, erbb-2 MeSH D12.776.543.750.060.437 - receptor, erbb-3 MeSH D12.776.543.750.060.468 - receptor, igf type 1 MeSH ... receptor, igf type 1 MeSH D12.776.543.750.750.400.780.410 - receptor, igf type 2 MeSH D12.776.543.750.750.400.820 - receptors, ... receptor, trkb MeSH D12.776.543.750.060.499 - receptor, trkc MeSH D12.776.543.750.060.500 - receptors, eph family MeSH D12.776. ...

... promoting B lymphocyte adhesion, motility and homing into marginal zones of spleen Estrogen Receptor. The NEDD9 interactors ... NEDD9 is involved in chemokine-induced T cell migration and T cell receptor (TCR)-mediated integrin activation. In lymphocytes ... B cell homing to the spleen and lymphocyte trafficking are deficient. The NEDD9 rs760678 SNP located in an intronic region, has ... "Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance". J. ...

He and his research team have shown that lymphocytes use a variety of different adhesion molecules or "homing receptors" to ... The team is also exploring mechanisms that imprint lymphocyte homing and chemokine receptor expression during tissue-specific ... To this end, they are studying the specialized homing mechanisms and functional properties of tissue infiltrating lymphocytes ... In other investigations, the team has identified novel lymphocyte, dendritic cell and macrophage chemoattractants and receptors ...

... breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of ... CCL28 regulates the chemotaxis of cells that express the chemokine receptors CCR3 and CCR10. CCL28 is expressed by columnar ...

... a cell adhesion protein on mucosal vascular endothelial cells that binds to the α4β7 homing receptor on lymphocytes. and 3) C-C ... chemokine receptor type 6, which is the lymphocyte receptor for CCL20. Working together, these genomic abnormalities are ... Duodenal-type follicular lymphoma (DFL) is a form of lymphoma in which certain lymphocyte types, the B-cell-derived centrocytes ... The highly express genes in both disorders include: 1) CCL20, a chemokine that is a chemoattractant for lymphocytes and 2) ...

"Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, ... September 2000). "Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish ... November 2000). "The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of ... July 2003). "CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype ...