Long non-coding RNA
Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that ... "Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology and Disease". Non-Coding RNA. 5 (1): 17. doi:10.3390/ ... "Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders". Non-Coding RNA. 7 (2): 36. ... "On the classification of long non-coding RNAs". RNA Biology. 10 (6): 925-933. doi:10.4161/rna.24604. PMC 4111732. PMID 23696037 ...
MORT (long non-coding RNA)
MORT (Mortal Obligate RNA Transcript (also known as ZNF667-AS1)) is a long non-coding RNA (lncRNA) of the intergenic type ( ... It is possible that the long life span of the great apes required evolution of additional genes with tumor suppressive activity ... Using data from human cancers curated in TCGA, MORT RNA expression and DNA methylation state were evaluated in the 10 most ... MORT has orthologs only in great apes - chimpanzees, gorillas and orangutans, and the RNA expression data indicates that the ...
List of long non-coding RNA databases
2014). "Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus ... This is a list of long noncoding RNA databases, which provide information about lncRNAs. Rinn, J. L.; Chang, H. Y. (2012). " ... "The landscape of long noncoding RNAs in the human transcriptome". Nature Genetics. 47 (3): 199-208. doi:10.1038/ng.3192. ISSN ... Integrative annotation of long noncoding RNAs". Nucleic Acids Research. 40 (Database issue): D210-D215. doi:10.1093/nar/gkr1175 ...
Small non-coding RNAs in the endosymbiotic diazotroph α-proteobacterium Sinorhizobium meliloti
Within genetics, post-genomic research has rendered bacterial small non-coding RNAs (sRNAs) as major players in post- ... The Alphaproteobacteria includes Gram-negative microorganisms with diverse life styles; frequently involving long-term ... "Identification of differentially expressed small non-coding RNAs in the legume endosymbiont Sinorhizobium meliloti by ... These new genomic loci were referred to as smr, for S. meliloti RNA. Seven of the Smr transcripts, which conservation is ...
Non-coding RNA
Another example of non-coding RNA dysregulated in cancer cells is the long non-coding RNA Linc00707. Linc00707 is upregulated ... between protein-coding and long noncoding RNAs and the elusive biological purpose of translation of long noncoding RNAs". ... VegT RNA, Oskar RNA, ENOD40, p53 RNA and SR1 RNA. Bifunctional RNAs have recently been the subject of a special issue of ... OxyS RNA is induced in response to oxidative stress in Escherichia coli.[citation needed] The B2 RNA is a small noncoding RNA ...
Circular RNA
For example: Circular ANRIL (cANRIL) is the circular form of ANRIL, a long non-coding RNA (ncRNA). Expression of cANRIL is ... However, a debranching failure can lead to the formation of circular intronic long non-coding RNAs, also known as ciRNAs. CiRNA ... September 2013). "Circular intronic long noncoding RNAs". Molecular Cell. 51 (6): 792-806. doi:10.1016/j.molcel.2013.08.017. ... microRNAs (miRNAs) are small (~21nt) non-coding RNAs that repress translation of messenger RNAs involved in a large, diverse ...
Fluorescence in situ hybridization
RNA Fluorescence in Situ Hybridization for the Simultaneous Detection of Immature and Mature Long Noncoding RNAs in Adherent ... June 2011). "Precursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity". RNA ... Long Non-Coding RNAs. Methods in Molecular Biology. Vol. 1402. Springer New York. pp. 119-134. doi:10.1007/978-1-4939-3378-5_10 ... RNA FISH or smFISH, is a method of detecting and quantifying mRNA and other long RNA molecules in a thin layer of tissue sample ...
GNAS complex locus
"Nespas". Long non-coding RNA db. Retrieved 3 May 2019. Freson K, Jaeken J, Van Helvoirt M, de Zegher F, Wittevrongel C, Thys C ... produce non-coding RNAs and may regulate imprinting in this region. In addition, one of the transcripts contains a second frame ... XLαs (Extra long alpha-s, Q5JWF2), paternal ALEX (Alternative gene product encoded by XL-exon, P84996), may inhibit XLαs NESP55 ... Three of the GNAS gene products, Gsα-long, Gsα-short, and XLαs, are different forms of Gsα, and differ mainly in the N-terminal ...
MIMT1
Long noncoding RNA Kim, J.; Bergmann, A.; Choo, J. H.; Stubbs, L. (2007). "Genomic organization and imprinting of the Peg3 ... also known as MIMT1 is a long non-coding RNA. It is an imprinted gene, which is paternally expressed. Deletion of this gene is ...
Sphinx (gene)
Long noncoding RNA Chen, Y.; Dai, H.; Chen, S.; Zhang, L.; Long, M. (2011). Kango-Singh, Madhuri (ed.). "Highly Tissue Specific ... In molecular biology, Sphinx (spx) is a long non-coding RNA found in Drosophila. It is expressed in the brain, within the ... Wang, W.; Brunet, F. G.; Nevo, E.; Long, M. (2002). "Origin of sphinx, a young chimeric RNA gene in Drosophilamelanogaster". ... Articles with short description, Short description matches Wikidata, Non-coding RNA). ...
RNA splicing
RNA 2013;19(2):141-57. Zhang Y, Zhang XO, Chen T, et al. Circular intronic long noncoding RNAs. Molecular cell 2013;51(6):792- ... Eukaryotes splice many protein-coding messenger RNAs and some non-coding RNAs. Prokaryotes, on the other hand, splice rarely ... transcript is transformed into a mature messenger RNA (mRNA). It works by removing all the introns (non-coding regions of RNA) ... Displacement of a splice site, leading to inclusion or exclusion of more RNA than expected, resulting in longer or shorter ...
Yar (gene)
In molecular biology, Yar (yellow-achaete intergenic RNA) is a long non-coding RNA found in Drosophila. It is located within a ... Long noncoding RNA Li, X.; Soshnev, A. A.; Wehling, M. D.; Geyer, P. K. (2008). Akhtar, Asifa (ed.). "Context Differences ... "A Conserved Long Non-coding RNA Affects Sleep Behavior in Drosophila". Genetics. 189 (2): 455-468. doi:10.1534/genetics. ...
Firre
... (functional intergenic repeating RNA element) is a long non-coding RNA located on chromosome X. It is retained in the ... Long non-coding RNA GRCh38: Ensembl release 89: ENSG00000213468 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... "Long noncoding RNAs regulate adipogenesis". Proceedings of the National Academy of Sciences of the United States of America. ... "Regulation of the ESC transcriptome by nuclear long noncoding RNAs". Genome Research. 25 (9): 1336-1346. doi:10.1101/gr. ...
MEG8
Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... is a long non-coding RNA. It is an imprinted gene, which is maternally expressed. It is expressed in the nucleus and (in an ... Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA). ... In molecular biology, Maternally expressed 8 (non-protein coding), also known as MEG8 or Rian (RNA Imprinted and Accumulated in ...
RNA
... and long RNAs are greater than 200 nt long. Long RNAs, also called large RNAs, mainly include long non-coding RNA (lncRNA) and ... According to the length of RNA chain, RNA includes small RNA and long RNA. Usually, small RNAs are shorter than 200 nt in ... Also, RNA-dependent RNA polymerase is part of the RNA interference pathway in many organisms. Messenger RNA (mRNA) is the RNA ... Biology portal Biomolecular structure RNA virus DNA History of RNA Biology List of RNA Biologists RNA Society Macromolecule RNA ...
DISC2
... is a long non-coding RNA molecule. In humans, the DISC2 gene that produces the DISC2 RNA molecule is located on chromosome 1, ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA). ...
HULC (gene)
Wang J, Liu X, Wu H, Ni P, Gu Z, Qiao Y, Chen N, Sun F, Fan Q (Sep 2010). "CREB up-regulates long non-coding RNA, HULC ... In molecular biology, Highly Up-regulated in Liver Cancer (non-protein coding), also known as HULC, is a long non-coding RNA. ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... Li D, Song YM, Zhan QM (Nov 2010). "[Specifically up-regulated non-coding RNA gene HULC in tumor cell lines and its effects on ...
DLG2-AS1
In molecular biology, DLG2 antisense RNA (non-protein coding), also known as DLG2AS, is a human long non-coding RNA. In humans ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... Kohtz JD, Berghoff EG (2010). "Regulatory long non-coding RNAs and neuronal disorders". Physiol Behav. 100 (3): 250-254. doi: ... Szymanski M, Barciszewska MZ, Erdmann VA, Barciszewski J (2005). "A new frontier for molecular medicine: noncoding RNAs". ...
FAS-AS1
In molecular biology, FAS antisense RNA (non-protein coding), also known as FAS-AS1 or SAF, is a long non-coding RNA. In humans ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... that the alternative splicing of Fas in lymphomas is tightly regulated by a long-noncoding RNA corresponding to an antisense ... Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA). ...
Ftx (gene)
Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... is a long non-coding RNA. In humans, it is located on the X chromosome. It was identified during sequence analysis of the X ... 2011). "Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region ... Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA). ...
TUG1
... (taurine upregulated gene 1) is a long non-coding RNA expressed in the retina and in the brain. It was first identified in ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 22, Non-coding RNA, All ... Young TL, Matsuda T, Cepko CL (March 2005). "The noncoding RNA taurine upregulated gene 1 is required for differentiation of ...
VIS1
... (viral integration site 1), also known as HIS-1, is a long non-coding RNA. It was originally identified in mice in a ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA). ... Askew DS, Li J, Ihle JN (March 1994). "Retroviral insertions in the murine His-1 locus activate the expression of a novel RNA ...
PRINS (gene)
PRINS (psoriasis associated RNA induced by stress) is a long non-coding RNA. Its expression is induced by stress, and it may ... Long noncoding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... March 2010). "The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS". Exp. ... v t e (Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA, All stub articles, ...
TCF21 (gene)
TCF21 activation is directed by an antisense long non-coding RNA, TARID (TCF21 antisense RNA inducing demethylation). TARID ... Rinn JL, Chang HY (2012). "Genome regulation by long noncoding RNAs". Annual Review of Biochemistry. 81: 145-66. doi:10.1146/ ... "Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A". Molecular Cell. 55 (4 ... orientation demonstrated that CGI3 harbors a promoter that directs the synthesis of a previously unknown long non-coding RNAs ( ...
Jeannie T. Lee
2013 Epigenetic regulation by long noncoding RNAs. JT Lee. Science, 2012 Genome-wide identification of polycomb-associated RNAs ... Science, 2008 Long noncoding RNAs: past, present, and future. JTY Kung, D Colognori, JT Lee. Genetics, ... Kung, Johnny T. Y.; Colognori, David; Lee, Jeannie T. (March 2013). "Long noncoding RNAs: past, present, and future". Genetics ... Lee, Jeannie T. (2012-12-14). "Epigenetic regulation by long noncoding RNAs". Science. 338 (6113): 1435-1439. Bibcode:2012Sci ...
LncRNAdb
In bioinformatics, lncRNAdb is a biological database of Long non-coding RNAs The database focuses on those RNAs which have been ... Long non-coding RNA Amaral, Paulo P; Clark Michael B; Gascoigne Dennis K; Dinger Marcel E; Mattick John S (Jan 2011). "lncRNAdb ... Official website v t e (Official website not in Wikidata, RNA, Non-coding RNA, Biological databases, All stub articles, ... a reference database for long noncoding RNAs". Nucleic Acids Res. England. 39 (Database issue): D146-151. doi:10.1093/nar/ ...
CLRN1-AS1
Long non-coding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... is a human gene encoding a long non-coding RNA. It was originally identified in a screen to identify the genes responsible for ... Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA). ... In molecular biology, CLRN1 antisense RNA 1 (CLRN1-AS1) (previously known as clarin 1 opposite strand, CLRN1OS or USH critical ...
Carolyn J. Brown
"Human cancer long non-coding RNA transcriptomes". PLOS ONE. 6 (10): e25915. Bibcode:2011PLoSO...625915G. doi:10.1371/journal. ... where she continued studying the XIST long noncoding RNA. Brown became Assistant Professor (1994) and Associate Professor (1999 ...
Polycomb recruitment in X chromosome inactivation
Pintacuda G, Young AN, Cerase A (2017). "Function by Structure: Spotlights on Xist Long Non-coding RNA". Frontiers in Molecular ... Cerase A, Tartaglia GG (September 2020). "Long non-coding RNA-polycomb intimate rendezvous". Open Biology. 10 (9): 200126. doi: ... Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT (October 2008). "Polycomb proteins targeted by a short repeat RNA to the mouse X ... Sunwoo H, Wu JY, Lee JT (August 2015). "The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and ...
DLEU2
Deleted in lymphocytic leukemia 2 (non-protein coding) is a long non-coding RNA that in humans is encoded by the DLEU2 gene. In ... Long non-coding RNA "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine ... v t e (Articles with short description, Short description matches Wikidata, Human genes, Non-coding RNA, All stub articles, ... "DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse". Genes, Chromosomes & Cancer. ...