Pyridoxal phosphate
... (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic ... Pyridoxal phosphate is a cofactor of ornithine carboxylase. Transamination. Pyridoxal phosphate takes part in decomposition and ... Pyridoxal phosphate has numerous roles in human body. A few examples below: Metabolism and biosynthesis of serotonin. Pyridoxal ... The condensation product of 3-hydroxy-1-aminoacetone phosphate and deoxyxylulose 5-phosphate is pyridoxine 5'-phosphate. The ...
Magnesium pyridoxal 5-phosphate glutamate
... (trade name Sedalipid) is a hypolipidemic agent. Schuitemaker GE, van der Pol GA, ... Aretz CP, Dinant GJ (2001). "A placebo-controlled, double-blind, randomised trial of magnesium-pyridoxal-5'-phosphate-glutamate ...
Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
... pyridoxal 5′-phosphate + 4 H2O + phosphate The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate. Burns ... is an enzyme with systematic name D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5′-phosphate-lyase. This enzyme ... pyridoxal 5′-phosphate + L-glutamate + 3 H2O + phosphate (overall reaction) (1a) L-glutamine + H2O ⇌ {\displaystyle \ ... Pyridoxal+5'-phosphate+synthase+(glutamine+hydrolyzing) at the U.S. National Library of Medicine Medical Subject Headings (MeSH ...
Diaminopimelate decarboxylase
"Pyridoxal phosphate". Pubchem. Retrieved 2018-03-09. Gillner DM, Becker DP, Holz RC (February 2013). "Lysine biosynthesis in ... It employs the cofactor pyridoxal phosphate, also known as PLP, which participates in numerous enzymatic transamination, ... Portal: Biology (EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of known structure). ...
Branched-chain amino acid aminotransferase
"Pyridoxal phosphate enzymology". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. Pyridoxal Phosphate Enzymology ... Like other transaminase enzymes (as well as many enzymes of other classes), BCATs require the cofactor pyridoxal-5'-phosphate ( ... In addition, the phosphate oxygen atoms on the PLP molecule interact with the Arg99, Val269, Val270, and Thr310 residues. ...
Histidine decarboxylase
"Pyridoxal phosphate-dependent decarboxylase". InterPro. Toney MD (January 2005). "Reaction specificity in pyridoxal phosphate ... The enzyme employs a pyridoxal 5'-phosphate (PLP) cofactor, in similarity to many amino acid decarboxylases. Eukaryotes, as ... Sandmeier E, Hale TI, Christen P (May 1994). "Multiple evolutionary origin of pyridoxal-5'-phosphate-dependent amino acid ... Fernandes HS, Ramos MJ, Cerqueira NM (July 2017). "The Catalytic Mechanism of the Pyridoxal-5'-phosphate-Dependent Enzyme, ...
Cystathionine beta-lyase
The enzyme belongs to the γ-family of PLP-dependent enzymes due to its use of a pyridoxal-5'-phosphate (PLP) cofactor to cleave ... Clausen T, Huber R, Laber B, Pohlenz HD, Messerschmidt A (September 1996). "Crystal structure of the pyridoxal-5'-phosphate ... John RA (April 1995). "Pyridoxal phosphate-dependent enzymes". Biochimica et Biophysica Acta (BBA) - Protein Structure and ... Alexander FW, Sandmeier E, Mehta PK, Christen P (February 1994). "Evolutionary relationships among pyridoxal-5'-phosphate- ...
Arginine decarboxylase
The process consumes a proton in the decarboxylation and employs a pyridoxal-5'-phosphate (PLP) cofactor, similar to other ... John RA (April 1995). "Pyridoxal phosphate-dependent enzymes". Biochimica et Biophysica Acta (BBA) - Protein Structure and ... EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of known structure). ... Toney MD (January 2005). "Reaction specificity in pyridoxal phosphate enzymes". Archives of Biochemistry and Biophysics. 433 (1 ...
Pyridoxine 5'-phosphate synthase
... phosphate, and pyridoxine-5'-phosphate (a vitamer of pyridoxal phosphate). In the first step of this condensation reaction, the ... phosphate + phosphate + 2 H2O The two substrates of this enzyme are 1-deoxy-D-xylulose 5-phosphate (DXP) and 3-hydroxy-1- ... pdxJ plays a role in the DXP-dependent pathway of pyridoxal phosphate. The DXP-dependent pathway is found predominantly in ... Mukherjee T, Hanes J, Tews I, Ealick SE, Begley TP (November 2011). "Pyridoxal phosphate: biosynthesis and catabolism". ...
Acetylornithine transaminase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 6 structures have been solved for this class of enzymes, with ... Portal: Biology v t e (Articles with short description, Short description matches Wikidata, EC 2.6.1, Pyridoxal phosphate ...
Beta-alanine-pyruvate transaminase
It employs one cofactor, pyridoxal phosphate. HAYAISHI O, NISHIZUKA Y, TATIBANA M, TAKESHITA M, KUNO S (1961). "Enzymatic ... Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ...
Asparagine-oxo-acid transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. MEISTER A, FRASER PE (1954). "Enzymatic formation of L-asparagine by ...
Adenosylmethionine-8-amino-7-oxononanoate transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, 11 structures have been solved for this class of enzymes, with ...
L-seryl-tRNASec selenium transferase
Portal: Biology v t e (EC 2.9.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, Transferase ... It employs one cofactor, pyridoxal phosphate. Forchhammer K, Bock A (1991). "Selenocysteine synthase from Escherichia coli. ... phosphate Thus, the two substrates of this enzyme are L-seryl-tRNASec and selenophosphate, whereas its two products are L- ... selenocysteinyl-tRNASec and phosphate. This enzyme belongs to the family of transferases, specifically those transferring ...
Threonine aldolase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 5 structures have been solved for this class of enzymes, with ... Portal: Biology v t e (Protein pages needing a picture, Genes on human chromosome 17, EC 4.1.2, Pyridoxal phosphate enzymes, ...
5-aminovalerate transaminase
It employs one cofactor, pyridoxal phosphate. Ichihara A, Ichihara EA, Suda M (1960). "Metabolism of L-lysine by bacterial ... Portal: Biology v t e (Articles with short description, Short description matches Wikidata, EC 2.6.1, Pyridoxal phosphate ...
D-amino-acid transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, 8 structures have been solved for this class of enzymes, with ...
Aminobenzoate decarboxylase
Portal: Biology v t e (EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 4.1 stubs). ... pyridoxal phosphate. McCullough WG, Piligian JT, Daniel IJ (1957). "Enzymatic decarboxylation of three aminobenzoates". J. Am. ...
Succinyldiaminopimelate transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. Peterkofsky B, Gilvarg C (May 1961). "N-Succinyl-L-diaminopimelic-glutamic ...
3-chloro-D-alanine dehydrochlorinase
Portal: Biology v t e (Articles with short description, Short description matches Wikidata, EC 4.5.1, Pyridoxal phosphate ... pyridoxal phosphate. Nagasawa T, Ishii T, Yamada H (1988). "Physiological comparison of D-cysteine desulfhydrase of Escherichia ...
Serine C-palmitoyltransferase
The PLP (pyridoxal 5′-phosphate)-dependent serine C-palmitoyltransferase carries out the first enzymatic step of de novo ... It employs one cofactor, pyridoxal phosphate. This enzyme belongs to the family of transferases, specifically those ... Eliot AC, Kirsch JF (2004). "Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations". Annual ... Pyridoxal phosphate enzymes, Enzymes of known structure). ...
Phenylalanine decarboxylase
Portal: Biology v t e (EC 4.1.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 4.1 stubs). ... It employs one cofactor, pyridoxal phosphate. Lovenberg W, Weissbach H, Udenfriend S (1962). "Aromatic L-amino acid ...
Arginine racemase
Portal: Biology v t e (EC 5.1.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, Isomerase stubs) ... It employs one cofactor, pyridoxal phosphate. Yorifuji T, Ogata K, Soda K (1969). "Crystalline arginine racemase". Biochem. ...
DTDP-4-amino-4,6-dideoxy-D-glucose transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. Matsuhashi M, Strominger JL (1966). "Thymidine diphosphate 4-acetamido-2,6- ...
1-Aminocyclopropane-1-carboxylate synthase
source) It is a pyridoxal phosphate (PLP) dependent gamma-elimination (?). In the gamma elimination, PLP acts as a sink twice ( ... They are natural toxins that cause slow binding inhibition by interfering with the coenzyme pyridoxal phosphate. ACC synthase ... It employs one cofactor, pyridoxal phosphate. The reaction catalyzed by 1-aminocyclopropane-1-carboxylic acid synthase (ACS) is ... it catalyzes the reaction through a quinonoid zwitterion intermediate and uses cofactor pyridoxal phosphate (PLP, the active ...
Glutamine-scyllo-inositol transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. Walker JB, Walker MS (1969). "Streptomycin biosynthesis. Transamination reactions ...
Glutamate-1-semialdehyde 2,1-aminomutase
Portal: Biology v t e (EC 5.4.3, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, Isomerase stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, 10 structures have been solved for this class of enzymes, with ...
Aminolevulinate transaminase
Portal: Biology v t e (EC 2.6.1, Pyridoxal phosphate enzymes, Enzymes of unknown structure, All stub articles, EC 2.6 stubs). ... It employs one cofactor, pyridoxal phosphate. Gibson KD, Matthew M, Neuberger A (1961). "Biosynthesis of porphyrins and ...
Amino-acid racemase
Portal: Biology v t e (EC 5.1.1, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, Isomerase stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, 5 structures have been solved for this class of enzymes, with ...
Glycine C-acetyltransferase
Portal: Biology v t e (EC 2.3.1, Pyridoxal phosphate enzymes, Enzymes of known structure, All stub articles, EC 2.3 stubs). ... It employs one cofactor, pyridoxal phosphate. As of late 2007, only one structure has been solved for this class of enzymes, ...