This type of phosphatase includes metal-dependent protein phosphatases (PPMs) and aspartate-based phosphatases. PP1 has been ... The herpes simplex virus protein ICP34.5 also activates protein phosphatase 1, which overcomes the cellular stress response to ... belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. ... Protein+Phosphatase+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (CS1: long ...

... phosphatase 2A protein]-leucine + methanol A key regulator of protein phosphatase 2A. Ogris E, Du X, Nelson KC, Mak EK, Yu XX, ... phosphatase 2A protein)-leucine ester acylhydrolase catalyses the reaction [phosphatase 2A protein]-leucine methyl ester + H2O ... is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A". The Journal of ... Protein+phosphatase+methylesterase-1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology ( ...

The gene encodes a subunit of myosin phosphatase. The encoded protein regulates the catalytic activity of protein phosphatase 1 ... "Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA". J. Biol. ... Protein phosphatase 1 regulatory subunit 12C is a protein that in humans is encoded by the PPP1R12C gene. ... "Entrez Gene: Protein phosphatase 1 regulatory subunit 12C". Retrieved 2016-11-14. Surks HK, Richards CT, Mendelsohn ME (2003 ...

The protein Tyr phosphatase (PTP) super-family forms the second group, and the aspartate-based protein phosphatases the third. ... A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its ... Phosphatases can be subdivided based upon their substrate specificity. Protein Ser/Thr phosphatases were originally classified ... This occurs on its own by hydrolysis, or is mediated by protein phosphatases. Protein phosphorylation plays a crucial role in ...

The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity ... Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. ... Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D (January 1999). "The structure of the protein phosphatase 2A PR65/A ... Ory S, Zhou M, Conrads TP, Veenstra TD, Morrison DK (August 2003). "Protein phosphatase 2A positively regulates Ras signaling ...

Protein tyrosine phosphatases (EC 3.1.3.48, systematic name protein-tyrosine-phosphate phosphohydrolase) are a group of enzymes ... LMW (low-molecular-weight) phosphatases, or acid phosphatases, act on tyrosine phosphorylated proteins, low-MW aryl phosphates ... dual-specificity protein-tyrosine phosphatases. Ser/Thr and Tyr dual-specificity phosphatases are a group of enzymes with both ... and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase". J. Biol. Chem. 267 ( ...

Janssens, V., & Goris, J. (2001). Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated ... and protein phosphatase 2A (PP2A) families. CAPPs are a subset of intracellular serine/threonine phosphatases. Each CAPP ... Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ... a novel potent heat-stable inhibitor protein of protein phosphatase 2A. Biochemistry, 35(22), 6998-7002. Mutz, D., Weise, C., ...

... phosphatase 2A protein]-leucine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + [phosphatase 2A protein]- ... phosphatase+2A+protein)-leucine-carboxy+methyltransferase at the U.S. National Library of Medicine Medical Subject Headings ( ... phosphatase 2A protein)-leucine-carboxy methyltransferase (EC 2.1.1.233, leucine carboxy methyltransferase-1, LCMT1) is an ... phosphatase 2A protein)-leucine O-methyltransferase. This enzyme catalyses the following chemical reaction S-adenosyl-L- ...

... and YwlE is a phosphatase-arginine-phosphatase (PAP). Many proteins rely on protein phosphatase activity for regulating their ... Also, that protein-arginine-phosphatases reverse the effect of protein arginine kinases (PAKs) in living organisms. In B. ... Protein Arginine Phosphatase (PAPs), also known as Phosphoarginine Phosphatase, is an enzyme that catalyzes the ... 2012), showed that McsB and YwlE are a protein arginine kinase and phosphatase, rather than a tyrosine kinase and phosphatase ...

Somlyo, Andrew P.; Somlyo, Avril V. (November 10, 1999). "Signal Transduction by G-Proteins, Rho-Kinase and Protein Phosphatase ... Because it is so important to basic cellular functions, and because there are far fewer protein phosphatases than kinases in ... While it is known that myosin phosphatase is regulated by rho-associated protein kinases, there is current debate about whether ... The enzyme is composed of three subunits: the catalytic region (protein phosphatase 1, or PP1), the myosin binding subunit ( ...

Takagi T, Moore CR, Diehn F, Buratowski S (June 1997). "An RNA 5′-triphosphatase related to the protein tyrosine phosphatases ... Wen Y, Yue Z, Shatkin AJ (October 1998). "Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism". ... Deshpande T, Takagi T, Hao L, Buratowski S, Charbonneau H (June 1999). "Human PIR1 of the protein-tyrosine phosphatase ... These enzymes are very much similar to protein tyrosine phosphatases in their structure and mechanism. This family includes ...

PHACTR1 is an actin and protein phosphatase 1 (PP1) binding protein that binds actin and regulates the reorganization of the ... A family of protein phosphatase 1 and actin regulatory proteins". Proceedings of the National Academy of Sciences of the United ... "MicroRNA-584 and the protein phosphatase and actin regulator 1 (PHACTR1), a new signaling route through which transforming ... "MicroRNA-584 and the protein phosphatase and actin regulator 1 (PHACTR1), a new signaling route through which transforming ...

Protein Tyrosine Phosphatase; Rab11a: Member RAS Oncogene Family; RGS2: Regulator Of G-Protein Signaling 2; RyR1: Ryanodine ... "TRPV6 protein expression summary". The Human Protein Atlas. Retrieved 2020-08-01. Lehen'kyi V, Raphaël M, Prevarskaya N (March ... Shin YC, Shin SY, So I, Kwon D, Jeon JH (January 2011). "TRIP Database: a manually curated database of protein-protein ... of proteins. The TRP family is a group of channel proteins critical for ionic homeostasis and the perception of various ...

This property can be used to determine the activity of various phosphatases including alkaline phosphatase (AP) and protein ... Lorenz, Ulrike (2017-05-07). "Protein Tyrosine Phosphatase Assays". Current Protocols in Immunology. 91 (1): 11.7.1-12. doi: ... "Analysis of Protein Tyrosine Phosphatases and Substrates". Current Protocols in Molecular Biology. 91 (1). doi:10.1002/ ... Phosphatases catalyze the hydrolysis of pNPP liberating inorganic phosphate and the conjugate base of para-nitrophenol (pNP). ...

Receptor tyrosine phosphatases are enzyme-linked receptor phosphatases, a sub-class of protein tyrosine phosphatases. Types ... v t e (Protein pages needing a picture, Transmembrane receptors, Single-pass transmembrane proteins, All stub articles, Enzyme ... Dudek RW (1 November 2006). High-yield cell and molecular biology. Lippincott Williams & Wilkins. pp. 19-. ISBN 978-0-7817-6887 ...

Dual specificity phosphatases (DUSPs) also belong to the family of protein thyrosine phosphatases. MKPs are grouped into type I ... MAPK phosphatases (MKPs) are the largest class of phosphatases involved in down-regulating Mitogen-activated protein kinases ( ... Camps, M. (22 May 1998). "Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase". Science. 280 ... Wu, JJ; Zhang, L; Bennett, AM (2005). "The Noncatalytic Amino Terminus of Mitogen-Activated Protein Kinase Phosphatase 1 ...

"Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA". J. Biol. ... mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein". J ... Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 is an enzyme that in humans is encoded by the AGAP3 gene. ... 2003). "GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins". Mol. Cell. Biol. 23 (7): 2476-2488. ...

Protein-tyrosine phosphatases PTPN14 and PTP-D1, PTP-RL10 and PTP2E. Caenorhabditis elegans protein phosphatase ptp-1. Chishti ... Non-receptor tyrosine-protein kinase TYK2. Protein-tyrosine phosphatases PTPN3 and PTPN4, enzymes that appear to act at ... Ezrin, moesin, and radixin are highly related proteins (ERM protein family), but the other proteins in which the FERM domain is ... In molecular biology, the FERM domain (F for 4.1 protein, E for ezrin, R for radixin and M for moesin) is a widespread protein ...

Imai discovered three kinds of protein tyrosine phosphatase (PTP) genes having the function of controlling the signal ... "Mammalian SH2-containing protein tyrosine phosphatase". Cell. 85 (1): 15. doi:10.1016/s0092-8674(00)81077-6. PMID 8620532. ... similarity in genomic organization within protein-tyrosine phosphatasegenes". Oncogene. 9 (10): 3031-3035. PMID 8084610. Adachi ... In addition, he produced monoclonal antibodies against CEA or ICAM-1 and found out they are usable in the diagnosis and the ...

Cho H (2013). "Protein tyrosine phosphatase 1B (PTP1B) and obesity". Vitamins and Hormones. 91: 405-24. doi:10.1016/B978-0-12- ... similar to squalamine that is an allosteric inhibitor of protein-tyrosine phosphatase 1B (PTP1B). It was isolated from the ... 407766-9.00017-1. ISBN 9780124077669. PMID 23374726. George J (April 29, 2009). "Biotech Genaera shutting down: Never brought ...

Protein phosphatase 1 counteracts phosphorylation of S695. PKC decreases channel opening probability by shortening the channel ... Slo binding proteins (Slobs) can modulate BK channels as a function of circadian rhythms in neurons. BK channels are expressed ... Mutations in the proteins involved with BK channels or genes encoding BK channels are involved in many diseases. A malfunction ... Inhibition of BK channel activity by phosphorylation of S695 by protein kinase C (PKC) is dependent on the phosphorylation of ...

Protein tyrosine phosphatase, mitochondrial 1 is a protein in humans that is primarily coded by the gene PTPMT1 gene. ... "Entrez Gene: Protein tyrosine phosphatase, mitochondrial 1". Retrieved 2017-01-12. Niemi NM, Lanning NJ, Westrate LM, MacKeigan ... of all the structure information available in the PDB for Mouse Phosphatidylglycerophosphatase and protein-tyrosine phosphatase ... 8 (1): e53803. Bibcode:2013PLoSO...853803N. doi:10.1371/journal.pone.0053803. PMC 3542197. PMID 23326511. PDBe-KB provides an ...

Human protein tyrosine phosphatases (PTPs) hold substantial relevance in human autoimmunity and T-cell receptor signaling, as ... "Chemical Probes of Protein Tyrosine Phosphatase Activity". Grantome. "Pharm Sci Seminar - Dr. Amy Barrios". School of Pharmacy ... Barrios' research lab focuses on developing probes to study protein tyrosine phosphatase (PTP) activity and regulation. Amy ... a tool that allows the visualization of tyrosine phosphatase activity in cells in real-time using protein tyrosine phosphatases ...

Protein phosphatase 1, regulatory subunit 27 is a protein in humans that is encoded by the PPP1R27 gene. ENSG00000288186 GRCh38 ... "Entrez Gene: Protein phosphatase 1, regulatory subunit 27". Retrieved 2012-11-18. v t e (Articles with short description, Short ... description matches Wikidata, Genes on human chromosome 17, Human proteins, All stub articles, Human chromosome 17 gene stubs) ...

Gu M, Majerus PW (1996). "The properties of the protein tyrosine phosphatase PTPMEG". J. Biol. Chem. 271 (44): 27751-9. doi: ... Identification of pancreas-specific protein as pancreatic procarboxypeptidase B." J. Biol. Chem. 267 (4): 2575-81. doi:10.1016/ ... is a protein that in humans is encoded by the PRSS1 gene. Trypsin-1 is the main isoform of trypsinogen secreted by pancreas, ... 44 (1): 8-15. doi:10.1016/j.dld.2011.08.003. PMID 21907651. Teich N, Mössner J, Keim V (1998). "Mutations of the cationic ...

"LIM-only protein FHL3 interacts with CDC25B2 phosphatase". Exp. Cell Res. 285 (1): 99-106. doi:10.1016/S0014-4827(03)00018-1. ... Four and a half LIM domains protein 3 is a protein that in humans is encoded by the FHL3 gene. LIM proteins are defined by the ... "Protein-protein interaction of FHL3 with FHL2 and visualization of their interaction by green fluorescent proteins (GFP) two- ... "Protein-protein interaction of FHL3 with FHL2 and visualization of their interaction by green fluorescent proteins (GFP) two- ...

... homeobox protein transcription factor CDX2; e) Protein tyrosine phosphatase receptor-type R gene PTPRR; f) transcriptional ... and ETV6-PER1 fusion genes produce chimeric proteins which lack ETV6 protein's gene-suppressing activity. The chimeric protein ... "PTPRR protein tyrosine phosphatase, receptor type R (human0". Entrez Gene. "IGH immunoglobulin heavy locus (human )". Entrez ... in germline DNA caused the lose of five base pairs ETV6 and a truncated ETV6 protein. Both mutant proteins failed to enter cell ...

Protein phosphatase 1 regulatory subunit 3G is a protein that is encoded by the PPP1R3G gene in humans. GRCh38: Ensembl release ... "Entrez Gene: Protein phosphatase 1 regulatory subunit 3G". Retrieved 2017-10-10. v t e (Articles with short description, Short ...

Dephosphorylation of calponin is catalyzed by type 2B protein phosphatase Unphosphorylated calponin binds to actin and inhibits ... Fraser ED, Walsh MP (July 1995). "Dephosphorylation of calponin by type 2B protein phosphatase". Biochemistry. 34 (28): 9151-8 ... Protein sequence alignment shows that calponin 1 is highly conserved in mammals but more diverged among lower vertebrates. The ... The CH domain was found in a number of actin-binding proteins (such as α-actinin, spectrin, and filamin) to form the actin- ...

Gunawardena, S. R.; Ruis, B. L.; Meyer, J. A.; Kapoor, M.; Conklin, K. F. (2007). "NOM1 Targets Protein Phosphatase I to the ... Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. ... Nucleolar protein with MIF4G domain 1 is a protein that in humans is encoded by the NOM1 gene. ... "Entrez Gene: Nucleolar protein with MIF4G domain 1". Retrieved 2011-09-27. "Dysmorphology data for Nom1". Wellcome Trust Sanger ...