L-lysine-procollagen, whereas its two products are UDP and 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen. This enzyme ... L-lysine-procollagen ⇌ {\displaystyle \rightleftharpoons } UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen Thus, ... In enzymology, a procollagen glucosyltransferase (EC 2.4.1.66) is an enzyme that catalyzes the chemical reaction UDP-glucose + ... The systematic name of this enzyme class is UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase. Other ...

... procollagen 5-(D-galactosyloxy)-L-lysine Thus, the two substrates of this enzyme are UDP-galactose and procollagen 5-hydroxy-L- ... In enzymology, a procollagen galactosyltransferase (EC 2.4.1.50) is an enzyme that catalyzes the chemical reaction UDP- ... The systematic name of this enzyme class is UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase. Other names ... lysine, whereas its two products are UDP and procollagen 5-(D-galactosyloxy)-L-lysine. This enzyme belongs to the family of ...

... procollagen aminoterminal protease, procollagen N-terminal proteinase, type I/II procollagen N-proteinase, type III procollagen ... Procollagen peptidase (EC 3.4.24.14, procollagen N-terminal peptidase, procollagen aminopeptidase, aminoprocollagen peptidase, ... "Procollagen peptidase". 7 October 2019. Lapière CM, Lenaers A, Kohn LD (December 1971). "Procollagen peptidase: an enzyme ... The MEROPS online database for peptidases and their inhibitors: Procollagen C-Peptidase:M12.005, Procollagen N-Peptidase: ...

... procollagen C-proteinase, procollagen carboxypeptidase, procollagen carboxy-terminal proteinase, procollagen peptidase) is an ... Procollagen C-endopeptidase (EC 3.4.24.19, procollagen C-terminal proteinase, carboxyprocollagen peptidase, procollagen C- ... Procollagen+C-endopeptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 3.4.24 ... Kessler E, Adar R (December 1989). "Type I procollagen C-proteinase from mouse fibroblasts. Purification and demonstration of a ...

... , commonly known as prolyl hydroxylase, is a member of the class of enzymes known as alpha- ... Procollagen-proline+dioxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Fe(2+) 2-oxoglutarate ... Procollagen-proline dioxygenase catalyzes the following reaction: L-proline + alpha-ketoglutaric acid + O2 → (2S, 4R)-4- ...

In enzymology, a procollagen-proline 3-dioxygenase (EC 1.14.11.7) is an enzyme that catalyzes the chemical reaction procollagen ... The 3 substrates of this enzyme are procollagen L-proline, 2-oxoglutarate, and O2, whereas its 3 products are procollagen trans ... The systematic name of this enzyme class is procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating). Other ... L-proline + 2-oxoglutarate + O2 ⇌ {\displaystyle \rightleftharpoons } procollagen trans-3-hydroxy-L-proline + succinate + CO2 ...

... is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the ... Procollagen cannot be processed correctly without this enzyme. As a result, collagen fibrils are not assembled properly; they ... Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary ... A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS2) also known as procollagen I N-proteinase (PC I-NP) ...

Potential role of procollagen C-proteinase". The Journal of Biological Chemistry. 271 (12): 7113-9. doi:10.1074/jbc.271.12.7113 ...

Procollagen C-endopeptidase enhancer 1 is an enzyme that in humans is encoded by the PCOLCE gene. Fibrillar collagen types I- ... "Entrez Gene: PCOLCE procollagen C-endopeptidase enhancer". Takahara K, Kessler E, Biniaminov L, et al. (1994). "Type I ... This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens activity. ... 1999). "Structural organization and expression patterns of the human and mouse genes for the type I procollagen COOH-terminal ...

Procollagen C-endopeptidase enhancer 2 is a protein that in humans is encoded by the PCOLCE2 gene. GRCh38: Ensembl release 89: ... "Entrez Gene: PCOLCE2 procollagen C-endopeptidase enhancer 2". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to ... Xu H, Acott TS, Wirtz MK (Sep 2000). "Identification and expression of a novel type I procollagen C-proteinase enhancer protein ... Steiglitz BM, Keene DR, Greenspan DS (2003). "PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a ...

The protein encoded by this gene is the major procollagen II N-propeptidase. This gene encodes a member of the ADAMTS (a ... The protein encoded by this gene is the major procollagen II N-propeptidase. Because of the high similarity to ADAMTS2, the ... "Procollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis". The Journal of Biological Chemistry. 276 ... major substrate of ADAMTS3 had been erroneously assumed to be procollagen II. However, ADAMTS3 appears largely irrelevant for ...

"Entrez Gene: PCOLN3 procollagen (type III) N-endopeptidase". Human CHMP1A genome location and CHMP1A gene details page in the ...

Kivirikko KI, Myllylä R (1985). "Post-translational processing of procollagens". Annals of the New York Academy of Sciences. ... Peterkofsky B (December 1991). "Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to ...

... comes from a family of pro-collagen molecules. This protein is found in the bone and is involved in calcium- ...

Retinoids also decrease procollagen mRNA in fibroblasts, improving pachyderma. Like retinoids, colchicines can also improve ...

Procollagen still has unwound ends, which will be later trimmed. At this point, the procollagen is packaged into a transfer ... This is not yet collagen but its precursor, procollagen. Procollagen is then modified by the addition of hydroxyl groups to the ... Procollagen is shipped to the Golgi apparatus, where it is packaged and secreted into extracellular space by exocytosis. ... Pre-pro-peptide to pro-collagen: Three modifications of the pre-pro-peptide occur leading to the formation of the alpha peptide ...

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 is an enzyme that in humans is encoded by the PLOD3 gene. The protein encoded ... "Entrez Gene: PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3". Salo AM, Wang C, Sipilä L, et al. (2006). "Lysyl ...

... the type I procollagen C-proteinase. Science, 271(5247), 360-362. Clark, T. G., Conway, S. J., Scott, I. C., Labosky, P. A., ... The Type I Procollagen C-Proteinas". Science. 271 (5247): 360-362. Bibcode:1996Sci...271..360K. doi:10.1126/science.271.5247. ... is a protease responsible for the biosynthetic processing of the precursor protein procollagen I into type I collagen, the most ...

Type III collagen is synthesized by cells as a pre-procollagen. The signal peptide is cleaved off producing a procollagen ... chain of human type III procollagen. Differences in protein structure from type I procollagen and conservation of codon ... Kontusaari S, Tromp G, Kuivaniemi H, Romanic AM, Prockop DJ (November 1990). "A mutation in the gene for type III procollagen ( ... Three identical type III procollagen chains come together at the carboxy-terminal ends, and the structure is stabilized by the ...

Katayama K, Armendariz-Borunda J, Raghow R, Kang AH, Seyer JM (May 1993). "A pentapeptide from type I procollagen promotes ...

BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone ... It however, is a metalloprotease that cleaves the C-terminus of procollagen I, II and III. It has an astacin-like protease ... PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the ... 1996). "The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified ...

... ropelike procollagen molecule. These procollagen molecules must be processed by enzymes in the cell. Once these molecules are ...

Prox J, Arnold P, Becker-Pauly C (May 2015). "Meprin α and meprin β: procollagen proteinases in health and disease". Matrix ...

Collagen V molecular isoforms are α1(V)α2(V)α3(V), α1(V)3, and α1(V)2 α2(V). These procollagen molecules are made up of three ... Procollagen molecules then form mature collagen with the help of enzymes. After the chains are formed, they arrange into thin ...

Recessive forms of OI relate heavily to defects in the collagen chaperones responsible for production of procollagen and the ... The mutations cause a decrease in secretion of trimeric procollagen molecules. Other mutations in this gene can cause autosomal ...

... chain of human type IV procollagen reveal an unusual homology of amino acid sequences in two halves of the carboxyl-terminal ... "Restricted homology between human alpha 1 type IV and other procollagen chains". Proceedings of the National Academy of ...

... "von Willebrand factor shares a distinctive cysteine-rich domain with thrombospondin and procollagen". Biochem. Biophys. Res. ...

The loss of these amino acids result in an abnormal procollagen II structure. The structure is not stable like the normal ... procollagen II structure and is normally degraded at a faster rate. Kniest dysplasia is an autosomal dominant condition. This ...

Collagen is synthesized as a soluble precursor, procollagen, which supports collagen self-assembly. Since collagen fibrils have ... Collagen serves as a precursor, procollagen, in synthesizing reaction, which identifies self-polymerization of collagen. There ...

This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein is ... Hjalt TA, Amendt BA, Murray JC (Feb 2001). "PITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: implications ...