Plasma membrane calcium-transporting ATPase 2 is an enzyme that in humans is encoded by the ATP2B2 gene. The protein encoded by ... The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these ... "Entrez Gene: ATP2B2 ATPase, Ca++ transporting, plasma membrane 2". Human ATP2B2 genome location and ATP2B2 gene details page in ... 1993). "von Hippel-Lindau syndrome: cloning and identification of the plasma membrane Ca(++)-transporting ATPase isoform 2 gene ...

Plasma membrane calcium-transporting ATPase 4 is an enzyme that in humans is encoded by the ATP2B4 gene. The protein encoded by ... The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these ... "Entrez Gene: ATP2B4 ATPase, Ca++ transporting, plasma membrane 4". Schuh K, Uldrijan S, Gambaryan S, Roethlein N, Neyses L ( ... This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different ...

Plasma membrane calcium-transporting ATPase 3 (PMCA3) is an enzyme that in humans is encoded by the ATP2B3 gene. The protein ... The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these ... "Entrez Gene: ATP2B3 ATPase, Ca++ transporting, plasma membrane 3". Human ATP2B3 genome location and ATP2B3 gene details page in ... 1992). "Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and ...

Plasma membrane Ca2+ ATPase (PMCA) Sarcoplasmic reticulum Ca2+ ATPase (SERCA) Plasma membrane Ca2+ ATPase (PMCA) is a transport ... Ca2+ ATPase is a form of P-ATPase that transfers calcium after a muscle has contracted. The two kinds of calcium ATPase are: ... which does not affect the plasma membrane Ca2+ pumps. Active transport#Counter-transport PDB Molecule of the Month Calcium pump ... the calcium pump in the sarcoplasmic reticulum membrane works in harmony with similar calcium pumps in the plasma membrane. ...

The plasma membrane Ca2+ ATPase and the sodium-calcium exchanger are together the main regulators of cytoplasmic Ca2+ ... transport of calcium out of the cell for the maintenance of the steep Ca2+ electrochemical gradient across the cell membrane. ... To maintain low concentrations of free Ca2+ in the cytosol, cells use membrane pumps like calcium ATPase found in the membranes ... "Calcium pump of the plasma membrane". Physiol. Rev. 71 (1): 129-53. doi:10.1152/physrev.1991.71.1.129. PMID 1986387. Strehler ...

... with the transport of calcium out of the cell. In addition, the plasma membrane Ca2+ ATPase (PMCA) obtains energy to pump ... In contrast, ionized calcium is a measure of free calcium. An abnormally high level of calcium in plasma is termed ... This gradient is maintained through various plasma membrane calcium pumps that utilize ATP for energy, as well as a sizable ... The amount of calcium in blood (more specifically, in blood plasma) can be measured as total calcium, which includes both ...

Plasma membrane calcium-transporting ATPase 1 also known as Plasma membrane calcium pump isoform 1 is a plasma membrane Ca2+ ... The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these ... "Entrez Gene: ATP2B1 ATPase, Ca++ transporting, plasma membrane 1". Lau MT, Manion J, Littleboy JB, Oyston L, Khuong TM, Wang QP ... "Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23". ...

The plasma membrane Ca2+ ATPase (PMCA) is a transport protein in the plasma membrane of cells that functions as a calcium pump ... doi:10.1016/0076-6879(88)57089-1. PMID 2976465.. Plasma+Membrane+Calcium-Transporting+ATPases at the U.S. National Library of ... "Plasma membrane calcium ATPase isoforms in astrocytes". Glia (published 1999-10-22). 28 (2): 150-155. doi:10.1002/(SICI)1098- ... "Expression and immunolocalization of plasma membrane calcium ATPase isoforms in human corneal epithelium". Mol. Vis. 11: 169- ...

Plasma membrane V-ATPases are involved in processes such as pH homeostasis, coupled transport, and tumor metastasis. V-ATPases ... For example, the proton gradient across the yeast vacuolar membrane generated by V-ATPases drives calcium uptake into the ... V-ATPases couple the energy of ATP hydrolysis to proton transport across intracellular and plasma membranes of eukaryotic cells ... Norepinephrine enters vesicles by V-ATPase[citation needed]. V-ATPases are also found in the plasma membranes of a wide variety ...

"Membrane potential-dependent calcium transport in right-side-out plasma membrane vesicles from Zea mays L. roots". The Plant ... Davies, J. M.; Hunt, I.; Sanders, D. (30 August 1994). "Vacuolar H(+)-pumping ATPase variable transport coupling ratio ... transport at the plasma membrane ofChara corallina I. Cotransport with H+". The Journal of Membrane Biology. 53 (2): 129-141. ... Sanders, D.; Hansen, U. P.; Slayman, C. L. (1 September 1981). "Role of the plasma membrane proton pump in pH regulation in non ...

Na+/K+-ATPase), the proton-potassium pump (H+/K+-ATPase), the calcium pump (Ca2+-ATPase) and the plasma membrane proton pump ( ... twofold). P2A ATPases (or Type IIA ATPases) are Ca2+ ATPases that transport Ca2+. P2A ATPases are split into two groups. ... P3A ATPases (or Type IIIA) contain the plasma membrane H+-ATPases from prokaryotes, protists, plants and fungi. Plasma membrane ... and the internal membranes (plants). Plasma membrane Ca2+-ATPase (PMCA) of animals is a P2B ATPase (TC# 3.A.3.2) P2C ATPases ( ...

Rao, R; Slayman, C W (April 1992). "Mutagenesis of the yeast plasma membrane H(+)-ATPase. A novel expression system". ... The lab uses yeast as a model organism with which to study the biology of cation transport channels. The specific transporters ... The Rao Lab identified the oncogenic role of SPCA2 in breast cancer through an aberrant method of signalling to calcium ... "Mutagenesis of Conserved Residues in the Phosphorylation Domain of the Yeast Plasma Membrane H(+)-ATPase. Effects on Structure ...

Another, more ubiquitous transmembrane pump that exports calcium from the cell is the plasma membrane Ca2+ ATPase (PMCA), which ... Since the transport is electrogenic (alters the membrane potential), depolarization of the membrane can reverse the exchanger's ... Such a primary transporter of calcium ions is present in the plasma membrane of most animal cells. ... by allowing Na+ to flow down its gradient across the plasma membrane in exchange for the countertransport of calcium ions (Ca2+ ...

V-ATPase can also be found within the plasma membrane. In mammals, location of the V-ATPase can be linked to the specific ... V-ATPase is also crucial in driving the transport of ions and small molecules into the cytoplasm, particularly calcium and ... In response to reduced plasma pH, increased levels of V-ATPase are typically trafficked to the plasma membrane in these cells ... Bafilomycins have been shown to inhibit plasma membrane ATPase (P-ATPase) as well as the ATP-binding cassette (ABC) ...

... force for DAT-mediated dopamine reuptake is the ion concentration gradient generated by the plasma membrane Na+/K+ ATPase. In ... activity-induced changes in membrane polarity can dramatically influence transport rates. In addition, the transporter may ... resulting in a calcium influx in dopamine neurons. This calcium influx is believed to induce CAMKII-mediated phosphorylation of ... In the substantia nigra, DAT is localized to axonal and dendritic (i.e., pre- and post-synaptic) plasma membranes. Within the ...

... apart from the population of Na/K-ATPase in the plasma membrane-responsible for ion transport --, there is another population ... is quickly returned to its normal concentration by a carrier enzyme in the plasma membrane, and a calcium pump in sarcoplasmic ... This enzyme belongs to the family of P-type ATPases. The Na⁺/K⁺-ATPase helps maintain resting potential, affects transport, and ... or sodium-potassium ATPase) is an enzyme (an electrogenic transmembrane ATPase) found in the membrane of all animal cells. It ...

Vacuolar-ATPases are responsible for transport of protons, while the counter transport of chloride ions is performed by ClC-7 ... the plasma membrane would continuously decrease in size. It is thought that lysosomes participate in this dynamic membrane ... Ambroxol triggers the exocytosis of lysosomes via neutralization of lysosomal pH and calcium release from acidic calcium stores ... While the plasma and lysosomal membranes are permeable for neutral and uncharged species of weak bases, the charged protonated ...

... nucleotidase activity in rat liver plasma membranes: Hepatic calcium-binding protein (regucalcin) reverses the Ca2+ effect". ... Regucalcin plays a role in the promotion of urinary calcium transport in the epithelial cells of kidney cortex. Overexpression ... Regucalcin has been shown to have an activatory effect on Ca pumping enzyme (Ca-ATPase) in heart sarcoplasmic reticulum. ... Shimokawa N, Yamaguchi M (June 1992). "Calcium administration stimulates the expression of calcium-binding protein regucalcin ...

While this pump is generally considered to be a plasma membrane protein, its presence has been recorded in the nuclear envelope ... Sodium and potassium play key roles in the sodium-potassium pump, a transmembrane ATPase that pumps three sodium ions out of ... NAD+ synthase is stored in the nucleoplasm and functions in electron transport and redox reactions involved with the electron ... Ions that have been documented in the nucleoplasm include sodium, potassium, calcium, phosphorus, and magnesium. These ions are ...

Na+/K+-ATPase can no longer maintain sodium/potassium ion concentration gradients across the plasma membrane. Glutamate ... This is linked to an inadequate supply of ATP, which drives the glutamate transport levels that keep the concentrations of ... Expression of NR2A mRNA has also been found to be altered in the inhibitory neurons that contain another calcium buffer, ... Barbado M, Fablet K, Ronjat M, De Waard M (June 2009). "Gene regulation by voltage-dependent calcium channels" (PDF). Biochim. ...

When Rab11FIP5 is knocked down, salivary cells cannot correctly translocate V-ATPase to the plasma membrane in response to ... the fast constitutive recycling route which allows for the direct transport of cargo from the endosome to the plasma membrane. ... Knockdown of Rab11FIP5 inhibited calcium-stimulated dense core vesicle (DCV) exocytosis in a neuroendocrine cell line BON cells ... DCV membrane proteins are lost to the plasma membrane during exocytosis and recycle to the Golgi through the retrograde ...

"Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps". Physiological Reviews. 81 (1 ... calcium pump, proton pump F-ATPase: mitochondrial ATP synthase, chloroplast ATP synthase V-ATPase: vacuolar ATPase ABC (ATP ... There are two forms of active transport, primary active transport and secondary active transport. In primary active transport, ... ISBN 978-0-321-77565-8. Transport into the Cell from the Plasma Membrane: Endocytosis - Molecular Biology of the Cell - NCBI ...

... and exit of Ca2+ from the basolateral side via the plasma membrane Ca2+ ATPase (PMCA1b). The hormone Vitamin D3 (or 1,25(OH)2D3 ... TRPV TRPV5 calcium channels calcium absorption transcellular pathway gating mechanism calmodulin maternal-fetal transport ... TRPV6 was also called calcium transport protein 1 (CaT1) initially although the names epithelial calcium channel 2 (ECaC2) and ... "Calcium channel TRPV6 is involved in murine maternal-fetal calcium transport". Journal of Bone and Mineral Research. 23 (8): ...

Schroeder JI (1988) K+ transport properties of K+ channels in the plasma membrane of Vicia faba guard cells. J. Gen. Physiol. ... Schroeder JI & Hagiwara S (1989) Cytosolic calcium regulates ion channels in the plasma membrane of Vicia faba guard cells. ... "Biochemical Evidence for the Requirement of 14-3-3 Protein Binding in Activation of the Guard-cell Plasma Membrane H+-ATPase by ... Ward JM & Schroeder JI (1994) Calcium-activated K++ channels and calcium-induced calcium release by slow vacuolar ion channels ...

... and methods of measuring plasma flow). He also investigated many membrane-related processes (water and ion transport, ... Tazawa showed that the extremely hyperpolarized membrane potential of Chara is due to an electrogenic H+ ATPase Tazawa has ... Okazaki, Y, Tazawa, M. (1990). "Calcium ion and turgor regulation in plant cells" (PDF). J. Membrane Biol. 114 (3): 189-194. ... indicating that there was an intrinsic polarity of the plasma membrane This work led to the first functional evidence for the ...

... removed from the cytoplasm through Na+/Ca2+ exchangers in the plasma membrane and by sarco/endoplasmic reticulum Ca2+ ATPases ( ... The calcium-sensitive nature of IP3Rs and RyRs makes both receptors capable of regenerative calcium-induced calcium release ( ... This observation suggests the SA might play a role in vesicular transport, although a specific mechanism is not yet clear. ... the spine apparatus could have a direct effect on the membrane potential of the spine plasma membrane when the synapse is ...

It is usually in internal plasma membranes. The V1 portion of the protein "is an ATPase" and is outside of the plasma membrane ... "ATP6V1G2 ATPase H+ transporting V1 subunit G2 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-04-20 ... Calcium and hydrogen antiporters are required for ATP6V1G2 to acidify the inside of the vesicle. The calcium is required to ... "Animal plasma membrane energization by proton-motive V-ATPases". BioEssays. 21 (8): 637-648. doi:10.1002/(SICI)1521-1878(199908 ...

... membrane glycoprotein - membrane protein - membrane topology - membrane transport - memory B cell - memory T cell - Mendelian ... plasma membrane - plasmid - plasmin - plasminogen - platelet glycoprotein GPIb-IX complex - platelet membrane glycoprotein - ... transmembrane ATPase - transmembrane helix - transmembrane protein - transmembrane receptor - transport protein - transport ... calcium channel - calcium signaling - calcium-binding protein - calmodulin - calmodulin-binding protein - Calvin cycle - CAM ...

The ion transport system moves potassium across the cell membrane using two mechanisms. One is active and pumps sodium out of, ... The movement of potassium and sodium through the cell membrane is mediated by the Na⁺/K⁺-ATPase pump. This ion pump uses ATP to ... Calcium is required to open the pores, although calcium may work in reverse by blocking at least one of the pores. Carbonyl ... Plasma potassium is normally kept at 3.5 to 5.5 millimoles (mmol) [or milliequivalents (mEq)] per liter by multiple mechanisms ...

Calcium-transporting ATPase type 2C member 1 is an enzyme that in humans is encoded by the ATP2C1 gene. This gene encodes one ... Mitchell KJ, Tsuboi T, Rutter GA (February 2004). "Role for plasma membrane-related Ca2+-ATPase-1 (ATP2C1) in pancreatic beta- ... "Entrez Gene: ATP2C1 ATPase, Ca++ transporting, type 2C, member 1". Human ATP2C1 genome location and ATP2C1 gene details page in ... This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. Defects in this gene ...