... which contains both phosphatidylcholine and deoxycholate (Figure 3). This bile salt is used to solubilize phosphatidylcholine ... Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of ... While phosphatidylcholines are found in all plant and animal cells, they are absent in the membranes of most bacteria, ... Phosphatidylcholines are such a major component of lecithin that in some contexts the terms are sometimes used as synonyms. ...
In enzymology, a phosphatidylcholine synthase (EC 2.7.8.24) is an enzyme that catalyzes the chemical reaction CDP- ... whereas its two products are CMP and phosphatidylcholine. This enzyme belongs to the family of transferases, specifically those ... "Cloning and characterization of the gene for phosphatidylcholine synthase". J. Biol. Chem. 275 (25): 18919-25. doi:10.1074/jbc. ... "Plant-exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase". J. Biol. Chem. 274 (28 ...
In enzymology, a phosphatidylcholine desaturase (EC 1.14.19.22, previously EC 1.3.1.35) is an enzyme that catalyzes the ... Slack CR, Roughan PG, Browse J (June 1979). "Evidence for an oleoyl phosphatidylcholine desaturase in microsomal preparations ... Stymne S, Appelqvist LA (October 1978). "The biosynthesis of linoleate from oleoyl-CoA via oleoyl-phosphatidylcholine in ...
In enzymology, a phosphatidylcholine 12-monooxygenase (EC 1.14.13.26) is an enzyme that catalyzes the chemical reaction 1-acyl- ...
In humans, phosphatidylcholine transfer protein is encoded by the PCTP gene. PCTP transfers phosphatidylcholine molecules ... "Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into ... Phosphatidylcholine transfer protein (PCTP), also known as StAR-related lipid transfer domain protein 2 (STARD2), is a specific ... "Entrez Gene: phosphatidylcholine transfer protein". van Helvoort A, de Brouwer A, Ottenhoff R, Brouwers JF, Wijnholds J, ...
In enzymology, a phosphatidylcholine---dolichol O-acyltransferase (EC 2.3.1.83) is an enzyme that catalyzes the chemical ... The systematic name of this enzyme class is 3-sn-phosphatidylcholine:dolichol O-acyltransferase. Keenan RW, Kruczek ME (1976 ... the two substrates of this enzyme are 3-sn-phosphatidylcholine and dolichol, whereas its two products are 1-acyl-sn-glycero-3- ... reaction 3-sn-phosphatidylcholine + dolichol ⇌ {\displaystyle \rightleftharpoons } 1-acyl-sn-glycero-3-phosphocholine + ...
In enzymology, a phosphatidylcholine---retinol O-acyltransferase (EC 2.3.1.135) is an enzyme that catalyzes the chemical ... The systematic name of this enzyme class is phosphatidylcholine:retinol---[cellular-retinol-binding-protein] O-acyltransferase ... Other names in common use include lecithin---retinol acyltransferase, phosphatidylcholine:retinol-(cellular-retinol-binding- ... the two substrates of this enzyme are phosphatidylcholine and [[retinol---[cellular-retinol-binding-protein]]], whereas its two ...
In enzymology, a phosphatidylcholine---sterol O-acyltransferase (EC 2.3.1.43) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is phosphatidylcholine:sterol O-acyltransferase. Other names in common use include ... the two substrates of this enzyme are phosphatidylcholine and sterol, whereas its two products are 1-acylglycerophosphocholine ... phosphatidylcholine + a sterol ⇌ {\displaystyle \rightleftharpoons } 1-acylglycerophosphocholine + a sterol ester Thus, ...
Phosphatidylcholines Phosphatidylcholines are lecithins. Choline is the alcohol, with a positively charged quaternary ammonium ... By contrast, the exoplasmic side (the side on the exterior of the cell) consists mainly of phosphatidylcholine and ... Phosphatidic acid synthesis in eukaryotes is different, there are two routes, one to the other toward phosphatidylcholine and ... Phosphatidylethanoamines, phosphatidylcholines, and other phospholipids are examples of phosphatidates. ...
Van Den Bosch H, Van Golde MG, Slotboom AJ, Van Deenen LL (1968). "The acylation of isomeric monoacyl phosphatidylcholines". ... phosphatidylcholine Thus, the two substrates of this enzyme are acyl-CoA and 2-acyl-sn-glycero-3-phosphocholine, whereas its ... two products are CoA and phosphatidylcholine. This enzyme belongs to the family of transferases, specifically those ...
1-LysoPC can be produced as a by-product of the reaction transferring an acyl group from a phosphatidylcholine to an acceptor ... Because they result from the hydrolysis of an acyl group from the sn-1 position of phosphatidylcholine, they are also called 1- ... A rat enzyme was found to transfer the acyl group from 2-lysoPC to 1-lysoPC, producing phosphatidylcholine. In the human body, ... LRAT-like protein (RLP-1; a product of the gene HRASLS5), catalyzes transfer of an acyl group from phosphatidylcholine (PC) to ...
... produces phosphatidylcholine when condensed with diacylglycerol. Phosphatidylcholine can also be produced by the methylation ... Phosphatidylcholine is synthesized in vivo by two pathways The Kennedy pathway, which includes the transformation of choline to ... Citicoline increases phosphatidylcholine synthesis. The mechanism for this may be: By converting 1, 2-diacylglycerol into ... Phosphatidylcholine is a major phospholipid in eukaryotic cell membranes. Close regulation of its biosynthesis, degradation, ...
16 September 2013). "Phosphatidylcholine and Related Lipids". AOCS Lipid Library. AOCS. Archived from the original on 11 ... Li Z, Agellon LB, Allen TM, Umeda M, Jewell L, Mason A, Vance DE (May 2006). "The ratio of phosphatidylcholine to ... DeLong CJ, Shen YJ, Thomas MJ, Cui Z (Oct 1999). "Molecular distinction of phosphatidylcholine synthesis between the CDP- ... Yao ZM, Vance DE (Feb 1988). "The active synthesis of phosphatidylcholine is required for very low density lipoprotein ...
Phosphatidylcholine is the major phospholipid in eukaryotic membranes. Phosphatidylcholine is important for a variety of ... Li Z, Agellon LB, Allen TM, Umeda M, Jewell L, Mason A, Vance DE (May 2006). "The ratio of phosphatidylcholine to ... Kent C (1990). "Regulation of phosphatidylcholine biosynthesis". Progress in Lipid Research. 29 (2): 87-105. doi:10.1016/0163- ... Choline kinase catalyzes the formation of phosphocholine, the committed step in phosphatidylcholine biosynthesis. ...
... is a phosphatidylcholine. It is a diacylglycerol and phospholipid. The full name is 1-palmitoyl-2-oleoyl-sn-glycero-3- ...
Lycopene - phosphatidylcholine - anti-inflammatory whey protein isolate. Lycopene - phosphatidylcholine - trans-resveratrol: ... phosphatidylcholine - simvastatin LycoD3, Lycopene - phosphatidylcholine - vitamin D3: 6 fold improvement in pharmacokinetics ... The lycopene and phosphatidylcholine complex with vitamin D3 is able not only to protect it from stomach acidity but also to ... Phospholipids, in particular phosphatidylcholine, play a critical role in this process as scaffolding for lipids, proteins and ...
In a phosphatidylcholine-based bilayer this process typically occurs over a timescale of weeks. This discrepancy can be ... Saturated phosphatidylcholine lipids with tails longer than 14 carbons are solid at room temperature, while those with fewer ... "Lateral diffusion in binary mixtures of cholesterol and phosphatidylcholines". Proceedings of the National Academy of Sciences ...
Currently, these liposomes are used in the study of the properties of this phosphatidylcholine and of its use as a mechanism of ... Ashton, M. R.; Postle, A. D.; Hall, M. A.; Smith, S. L.; Kelly, F. J.; Normand, I. C. (April 1992). "Phosphatidylcholine ... DPPC is a variant of phosphatidylcholine. Its structure includes both a hydrophilic "head" and hydrophobic "tails", and it is ... More specifically, it has been found that phosphatidylcholine (PC) is the most abundant phospholipid (70%-85%), and that PC is ...
Phosphatidylcholines are needed for the synthesis of VLDLs: 70-95% of their phospholipids are phosphatidylcholines in humans. ... For example, phosphatidylcholines (PC) can be hydrolyzed to choline (Chol) in most cell types. Choline can also be produced by ... Phosphatidylcholine levels in the plasma of fasting adults is 1.5-2.5 mmol/L. Its consumption elevates the free choline levels ... Phosphatidylcholines are excreted into bile and work together with bile acid salts as surfactants in it, thus helping with the ...
Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. Model organisms have been used in the study of PLA2G6 ... helps to regulate the levels of a compound called phosphatidylcholine, which is abundant in the cell membrane. The encoded ...
Because it contains phosphatidylcholines, lecithin is a source of choline, an essential nutrient. One publication found no ... In 1850, he named the phosphatidylcholine lécithine. Gobley originally isolated lecithin from egg yolk and established the ... Some phospholipids, such as phosphatidylcholine, have good solubility in ethanol, whereas most other phospholipids do not ... Complex mixture of phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidic acid, glycolipids, etc. ...
"Legionella bozemanae synthesizes phosphatidylcholine from exogenous choline". Microbiological Research. 166 (2): 87-98. doi: ...
Injection increases synthesis of diacylglycerol from phosphatidylcholine. Some meiosis effects are antagonized by rap1 (and by ...
This practice, using drugs generally based on phosphatidylcholine and deoxycholate (PCDC), evolved from the initial intravenous ... 2004). "Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review". Dermatologic Surgery. 30 (3 ... "The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads". Dermatologic Surgery. 27 (4): ... "Phosphatidylcholine in the treatment of localized fat". Journal of Drugs in Dermatology. 2 (5): 511-8. PMID 14558399.{{cite ...
... phosphatidylcholine-retinol O-acyltransferase; EC 3.1.1.64, retinoid isomerohydrolase; and EC 1.1.1.315, 11-cis-retinol ...
Phosphatidylcholine (PC)-specific phospholipases D (PLDs) EC 3.1.4.4 catalyze the hydrolysis of PC to produce phosphatidic acid ... "Entrez Gene: PLD1 phospholipase D1, phosphatidylcholine-specific". Andersson L, Boström P, Ericson J, Rutberg M, Magnusson B, ... December 1995). "Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly ...
"Reduced metribuzin pollution with phosphatidylcholine-clay formulations". Pest Management Science. 67 (3): 271-278. doi:10.1002 ...
Kim KP, Han SK, Hong M, Cho W (2000). "The molecular basis of phosphatidylcholine preference of human group-V phospholipase A2 ... It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce ...
Batna, A; Spiteller, G (1994). "Effects of soybean lipoxygenase-1 on phosphatidylcholines containing furan fatty acids". Lipids ...
Albon, Norman (1978). "Nature of the gel to liquid crystal transition of synthetic phosphatidylcholines". Proceedings of the ... Phosphatidylcholine molecules form ~85% of the lipid in surfactant and have saturated acyl chains. Phosphatidylglycerol (PG) ...