"Diketopiperazines as neuroprotective agents". Mini Reviews in Medicinal Chemistry. 12 (1): 2-12. doi:10.2174/138955712798868959 ... Derivatives of cyclo(L-His-L-Pro) have been studied extensively to develop therapeutic agents for neurodegeneration. These ... The unsaturated derivatives are illustrated by phenylahistin the anti-cancer microtubule binding agent, and the mycotoxin ... an antibacterial agent used as food additives to prevent diarrhea in animals while the thio derivatives such as the cytotoxic ...
"Carboxyfullerenes as neuroprotective agents". Proceedings of the National Academy of Sciences of the United States of America. ... The same year, a carboxylated fullerene dubbed C3 was reported to be neuroprotective in a primate model of Parkinson's disease ...
Bordi F, Mugnaini M, Terron A, Barnaby R, Reggiani A (June 2000). "GV150526: a neuroprotective agent". CNS Drug Reviews. 6 (2 ... Jeffrey S (4 April 2001). "GAIN Americas trial again shows no benefit from neuroprotectant agent in stroke". Medscape News. ...
Brimble MA, Levi MS (2010). "A Review of Neuroprotective Agents". In Atta-ur-Rahman, Reitz AB (eds.). Frontiers in Medicinal ...
Dodd S, Maes M, Anderson G, Dean OM, Moylan S, Berk M (April 2013). "Putative neuroprotective agents in neuropsychiatric ... Dodd S, Maes M, Anderson G, Dean OM, Moylan S, Berk M (April 2013). "Putative neuroprotective agents in neuropsychiatric ... Seidl SE, Potashkin JA (2011). "The promise of neuroprotective agents in Parkinson's disease". Frontiers in Neurology. 2: 68. ... Zhao YY, Yu JZ, Li QY, Ma CG, Lu CZ, Xiao BG (May 2011). "TSPO-specific ligand vinpocetine exerts a neuroprotective effect by ...
Maas AI (April 2001). "Neuroprotective agents in traumatic brain injury". Expert Opinion on Investigational Drugs. 10 (4): 753- ... This is counterbalanced by the risk of developing Olney's lesions, and studies have started to find agents that prevent this ... Farber N, Jiang X, Heinkel C, Nemmers B (23 August 2002). "Antiepileptic drugs and agents that inhibit voltage-gated sodium ... Farber NB, Hanslick J, Kirby C, McWilliams L, Olney JW (January 1998). "Serotonergic agents that activate 5HT2A receptors ...
Neuroprotective Agents and Antidepressant Therapy. New Delhi: Springer India. pp. 1-23. doi:10.1007/978-81-322-2803-5_1. ISBN ...
Xu X, Chua CC, Gao J, Hamdy RC, Chua BH (October 2006). "Humanin is a novel neuroprotective agent against stroke". Stroke. 37 ( ... Beyond the possible neuroprotective effects, humanin protects against oxidative stress, atherosclerotic plaque formation, and ... Humanin is proposed to have myriad neuroprotective and cytoprotective effects. Both studies in cells and rodents have both ... Experiments using cultured cells have demonstrated that humanin has both neuroprotective as well as cytoprotective effects and ...
Kopecky, Benjamin J.; Liang, Ruqiang; Bao, Jianxin (2014). "T-type Calcium Channel Blockers as Neuroprotective Agents". ...
"Mitochondria as a target for neurotoxins and neuroprotective agents". Annals of the New York Academy of Sciences. 993 (1): 334- ... June 2001). "Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer". Annals of the New York Academy of ... Research was conducted in both Russia and western nations into potential applications as a neuroprotective drug to treat ... and may exert a neuroprotective effect by blocking a novel target that involves mitochondrial pores, which are believed to play ...
A Class of Promising Neuroprotective Agents for Parkinson Disease". In Brahmachari G (ed.). Discovery and Development of ... Neuroprotective Agents from Natural Products. Elsevier Science. p. 32. doi:10.1016/B978-0-12-809593-5.00002-1. ISBN 978-0-12- ... Nabavi SF, Braidy N, Habtemariam S, Orhan IE, Daglia M, Manayi A, Gortzi O, Nabavi SM (2015). "Neuroprotective effects of ... Samarghandian S, Farkhondeh T, Azimi-Nezhad M (2017). "Protective Effects of Chrysin Against Drugs and Toxic Agents". Dose- ...
Agents currently under investigation as neuroprotective agents include anti-apoptotic drugs (omigapil, CEP-1347), ... Researchers are attempting to develop neuroprotective agents for Parkinson's disease, as well as other neurodegenerative brain ... Exercise may be neuroprotective. Animal studies show exercise may protect against dopaminergic neurotoxins, and research ... Several molecules have been proposed as potential neuroprotective treatments. However none of them has been conclusively ...
He Y, Benz A, Fu T, Wang M, Covey DF, Zorumski CF, Mennerick S (February 2002). "Neuroprotective agent riluzole potentiates ... receptor subunit expression by pharmacological agents" (PDF). Pharmacological Reviews. 62 (1): 97-135. doi:10.1124/pr. ...
Tsai JC, Song BJ, Wu L, Forbes M (September 2007). "Erythropoietin: a candidate neuroprotective agent in the treatment of ... Anti-VEGF agents as injectable medications, along with other standard of care treatment for decreasing intraocular pressure, ... The possible neuroprotective effects of various topical and systemic medications are also being investigated. Poor compliance ... Vascular flow and neurodegenerative theories of glaucomatous optic neuropathy have prompted studies on various neuroprotective ...
Currently, no proven neuroprotective agents or treatments are available for PD. While still theoretical, neuroprotective ... and neuroprotective agents. The tragedy of a group of drug addicts in California in the early 1980s who consumed a contaminated ... Accordingly, neuroprotective therapy seeks to delay the introduction of levodopa. Several molecules have been proposed as ... In such cases, specific measures include the use of thickening agents for liquid intake, special postures when eating, and ...
Since that time, the class has been expanded by scientific research into stimulant, analgesic, and neuroprotective agents, and ... These are versatile agents with a wide range of possible pharmacological activities depending on the extent and range to which ... Antagonism of the NMDA receptor confers anesthetic, anticonvulsant, neuroprotective, and dissociative effects; blockade of the ... and D2 receptor agonistic actions have been reported for some of these agents. ...
"Progress in Dodecafluoropentane Emulsion as a Neuroprotective Agent in a Rabbit Stroke Model". Molecular Neurobiology. 48 (2): ... Notable ultrasound contrast agents include DEFINITYⓇ and OptisonTM which are FDA approved, SONAZOIDⓇ which is approved in Japan ... Some of them are commonly used in medicine as ultrasound contrast agents, and others have been studied for use as oxygen ... "Ultrasound Contrast Agent Sonazoid® for Injection Released for Sale" (PDF). Retrieved 9 December 2021. European Medicines ...
Hirbec H, Gaviria M, Vignon J (2001). "Gacyclidine: a new neuroprotective agent acting at the N-methyl-D-aspartate receptor". ... It is therefore concluded that Gacyclidine exhibits neuroprotective effects close to those of other antagonists of the NMDA ... receptor, with the benefit of being slightly less neuroprotective. Gacyclidine being a psychoactive drug and its chemical ...
... an endogenous neuroprotective agent for ischemic stroke". Stroke. 44 (1): 205-12. doi:10.1161/STROKEAHA.112.673954. PMC 3678096 ... Carnosine demonstrated neuroprotective effects in multiple animal studies. Research has demonstrated a positive association ... Rajanikant, GK; Zemke, D; Senut, MC; Frenkel, MB; Chen, AF; Gupta, R; Majid, A (November 2007). "Carnosine is neuroprotective ... Reddy, V. P.; Garrett, MR; Perry, G; Smith, MA (2005). "Carnosine: A Versatile Antioxidant and Antiglycating Agent". Science of ...
January 2010). "The functional and neuroprotective actions of Neu2000, a dual-acting pharmacological agent, in the treatment of ... October 2013). "Progress in dodecafluoropentane emulsion as a neuroprotective agent in a rabbit stroke model". Molecular ... June 2017). "Neuroprotective effects of a novel poly (ADP-ribose) polymerase-1 inhibitor, JPI-289, in hypoxic rat cortical ... Egi Y, Matsuura S, Maruyama T, Fujio M, Yuki S, Akira T (May 2011). "Neuroprotective effects of a novel water-soluble poly(ADP- ...
They also showed that interleukin 1 receptor antagonist is an endogenous neuroprotective agent. They have shown that the ... "Endogenous interleukin-1 receptor antagonist is neuroprotective". Biochemical and Biophysical Research Communications. 234 (1 ...
... an anesthetic agent with neuroprotective properties". CNS Neuroscience & Therapeutics. 14 (2): 95-106. doi:10.1111/j.1527- ... glycerol as a tonicity-adjusting agent, and sodium hydroxide to adjust the pH. Diprivan contains EDTA, a common chelation agent ... Mild myoclonic movements are common, as with other intravenous hypnotic agents. Propofol appears to be safe for use in ... Larijani GE, Gratz I, Afshar M, Jacobi AG (October 1989). "Clinical pharmacology of propofol: an intravenous anesthetic agent ...
There is no evidence that donepezil or other similar agents alter the course or progression of Alzheimer's disease. Six-to- ... Donepezil upregulates the nicotinic receptors in the cortical neurons, adding to neuroprotective property. It inhibits voltage- ... Donepezil was claimed to act synergistically with an agent called FK962 [283167-06-6] & FK960 [133920-70-4]. {potential ... Antidementia agents, Lewy body dementia, Treatment of Alzheimer's disease, Nootropics, Pfizer brands, Piperidines, Catechol ...
Neznamov GG, Siuniakov SA, Chumakov DV, Bochkarev VK, Seredenin SB (2001). "[Clinical study of the selective anxiolytic agent ... It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.[citation needed] Its ... Silkina IV, Gan'shina TC, Seredin SB, Mirzoian RS (2005). "[Gabaergic mechanism of cerebrovascular and neuroprotective effects ...
There is also no biological control agent available in helping control this species. Mechanical and chemical methods are being ... Bicelaphanol A is a neuroprotective dimeric-trinorditerpene isolated from the bark of Celastrus orbiculatus. Despite the modest ... dimeric trinorditerpenes with promising neuroprotective activity from Celastrus orbiculatus". Journal of Natural Products. 76 ( ...
un MK, Wüstmann DJ, Herzon SB (2011). "A robust and scalable synthesis of the potent neuroprotective agent (−)-huperzine A". ... Bai DL, Tang XC, He XC (March 2000). "Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease". Current ... Huperzine A might be useful in the treatment of organophosphate nerve agent poisoning, preventing damage to the central nervous ... Zangara A (June 2003). "The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective ...
Other potentially neuroprotective agents under investigation in clinical trials include cethrin, erythropoietin, and ... Iron from blood damages the spinal cord through oxidative stress, so one option is to use a chelation agent to bind the iron; ...
"Which neuroprotective agents are ready for bench to bedside translation in the newborn infant?." The Journal of pediatrics 160 ... "Cerebral hypothermia is not neuroprotective when started after postischemic seizures in fetal sheep." Pediatric research 46, no ...
"Novel Stachydrine-Leonurine Conjugate SL06 as a Potent Neuroprotective Agent for Cerebral Ischemic Stroke". ACS Chemical ... Shi, Xue Ru; Hong, Zhen Yi; Liu, Hong Rui; Zhang, Yu Chen; Zhu, Yi Zhun (1 July 2011). "Neuroprotective effects of SCM198 on 6- ... and protects against oxidative damage from ischemic stroke and demonstrates neuroprotective activity against focal cerebral ... a novel potential cardiovascular agent, in rat plasma by liquid chromatography-tandem mass spectrometry and its application to ...
... a Cannabidiol-Derived Neuroprotective Agent, with Improved Potency, Safety, and Permeability". ACS Med. Chem. Lett. 7 (4): 424- ... Kannalife was formed in 2010 and is involved in the research and development of novel new therapeutic agents designed to reduce ...