However, at about the 11th hour, most myoblasts fail to fuse. As development progresses, some myoblasts show signs of fusion, ... "Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal ... myoblast+city+protein,+Drosophila at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Protein pages ... The Myoblast city locus was identified by deletion mapping, using this technique researchers were able to isolate the location ...

Blau, H. M.; Dhawan, J.; Pavlath, G. K. (1993-08-01). "Myoblasts in pattern formation and gene therapy". Trends in Genetics. 9 ... Blau, H. M.; Webster, C.; Pavlath, G. K. (1983-08-01). "Defective myoblasts identified in Duchenne muscular dystrophy". ...

... is an immortalized mouse myoblast cell line. The C2C12 cell line is a subclone of myoblasts that were originally obtained ... Mononucleated myoblasts can later fuse to form multinucleated myotubes under low serum conditions or starvation, leading to the ... In their study, a set of C2C12 cells were cultured from normal mouse myoblasts, which were cultured from 2-month old C3H mice ... Developed for in vitro studies of myoblasts isolated from the complex interactions of in vivo conditions, C2C12 cells are ...

1998). "Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion". FEBS Lett. 434 (1-2 ... This gene is not expressed in differentiating myoblasts. Alternative splicing results in three transcript variants encoding ...

Recently, phosphorylation of ceramide via CERK has been shown to stimulate myoblast proliferation. It was demonstrated that C-1 ... "Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts". Biochimie. 94 (3): 597-607. doi:10.1016/j.biochi.2011.09.009 ...

Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene ... In Setdb1 depleted myoblasts that are treated with exogenous MyoD, myoblastic differentiation is successfully restored. In one ... The function of MyoD in development is to commit mesoderm cells to a skeletal myoblast lineage, and then to regulate that ... MyoD, also known as myoblast determination protein 1, is a protein in animals that plays a major role in regulating muscle ...

When the growth factor runs out, the myoblasts cease division and undergo terminal differentiation into myotubes. Myoblast ... c-Met is a tyrosine kinase receptor that is required for the survival and proliferation of migrating myoblasts. A lack of c-Met ... The second stage of differentiation involves the alignment of the myoblasts with one another. Studies have shown that even rat ... If placed in cell culture, most myoblasts will proliferate if enough fibroblast growth factor (FGF) or another growth factor is ...

Doherty KR, Cave A, Davis DB, Delmonte AJ, Posey A, Earley JU, Hadhazy M, McNally EM (December 2005). "Normal myoblast fusion ... However, it has been shown experimentally that loss of myoferlin results in reduced myoblast fusion and muscle size. There is ...

The fusion of myoblasts is specific to skeletal muscle, and not cardiac muscle or smooth muscle. Myoblasts in skeletal muscle ... Muscle cells (including myocytes and muscle fibers) develop from embryonic precursor cells called myoblasts. Myoblasts fuse ... this multinucleate condition results from multiple myoblasts fusing to produce each muscle fiber, where each myoblast ... A myoblast is an embryonic precursor cell that differentiates to give rise to the different muscle cell types. Differentiation ...

Knudsen, KA; Horwitz, AF (1978). "Toward a mechanism of myoblast fusion". Prog Clin Biol Res. 23: 563-8. PMID 96453. Baerwald ...

Davis RL, Weintraub H, Lassar AB (1987). "Expression of a single transfected cDNA converts fibroblasts to myoblasts". Cell. 51 ...

Davis RL, Weintraub H, Lassar AB (December 1987). "Expression of a single transfected cDNA converts fibroblasts to myoblasts". ... "Transfection of a DNA locus that mediates the conversion of 10T1/2 fibroblasts to myoblasts". Cell. 47 (5): 649-56. doi:10.1016 ...

It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. ... "Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion". FEBS Letters. 434 (1-2): 177 ...

Forcing mouse embryonic fibroblasts to express MyoD was found to be sufficient to turn those cells into myoblasts. The only[ ... Davis, R. L.; Weintraub, H.; Lassar, A. B. (1987). "Expression of a single transfected cDNA converts fibroblasts to myoblasts ... 5-azacytidine is also known to promote phenotypic transdifferentiation of cardiac cells to skeletal myoblasts. In prostate ...

Davis, R. L.; Weintraub, H.; Lassar, A. B. (1987). "Expression of a single transfected cDNA converts fibroblasts to myoblasts ... myoblasts (MyoD) Fibroblasts → melanocytes (MITF) Glial cells → neurons (Pax6) Erythorid-megakaryocytic cells → monocytic cells ...

"Autologous skeletal myoblasts transplanted to ischemia-damaged myocardium in humans". Journal of the American College of ...

"Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts". J. Biol. Chem. 280 (27): 25788-801. doi:10.1074/ ...

E-box required for maximal expression in neuroblastoma and myoblasts". The Journal of Biological Chemistry. 275 (22): 16560- ...

... is required for myoblast fusion". J. Biol. Chem. 275 (18): 13933-9. doi:10.1074/jbc.275.18.13933. PMID 10788519. Shi Z, Xu W, ... is required for myoblast fusion". J. Biol. Chem. 275 (18): 13933-9. doi:10.1074/jbc.275.18.13933. PMID 10788519. Iba K, ... "A metalloprotease-disintegrin participating in myoblast fusion". Nature. 377 (6550): 652-6. Bibcode:1995Natur.377..652Y. doi: ...

"Apoptosis and differentiation of Xenopus tail-derived myoblasts by thyroid hormone". Journal of Molecular Endocrinology. 54 (3 ...

"Apoptosis and differentiation of Xenopus tail-derived myoblasts by thyroid hormone". Journal of Molecular Endocrinology. 54 (3 ...

"Involvement of Ras and Ral in Chemotactic Migration of Skeletal Myoblasts". Mol. Cell. Biol. 20 (13): 4658-65. doi:10.1128/MCB. ...

"Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts". Molecular and Cellular Biology. 20 (13): 4658-65. ...

Gartner TK, Podleski TR (December 1975). "Evidence that a membrane bound lectin mediates fusion of L6 myoblasts". Biochemical ...

... may also interact with Akt and insulin in myoblasts in vitro. Mutations in PLD3 have been studied for their potential role ... Increased PLD3 expression was shown to increase myotube formation in differentiated mouse myoblasts in vitro, and ER stress ... Overexpression of PLD3 in mouse myoblasts in vitro may inhibit Akt phosphorylation and block signal transduction during insulin ... Over-expression of phospholipase D3 inhibits Akt phosphorylation in C2C12 myoblasts]". Sheng Wu Gong Cheng Xue Bao = Chinese ...

... isoforms in differentiating myoblasts". J. Muscle Res. Cell. Motil. 20 (7): 669-79. doi:10.1023/A:1005524623337. PMID 10672515 ...

"Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts". Molecular and Cellular Biology. 20 (13): 4658-65. ...

"Apoptosis and differentiation of Xenopus tail-derived myoblasts by thyroid hormone". J Mol Endocrinol. 54 (3): 185-192. doi: ...

"Pax3 inhibits myogenic differentiation of cultured myoblast cells". The Journal of Biological Chemistry. 270 (20): 11719-11722 ...

In fact, inhibition of IFRD1 function in C2C12 myoblasts, by antisense IFRD1 cDNA transfection or microinjection of anti-IFRD1 ... Guardavaccaro D, Ciotti MT, Schäfer BW, Montagnoli A, Tirone F (1995). "Inhibition of differentiation in myoblasts deprived of ... "PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and ...