The prerequisite for molecular mimicry to occur is thus the sharing of the immunodominant epitope between the pathogen and the ... Molecular mimicry, from these examples, has therefore been shown to occur also in the absence of any true sequence homology. ... Molecular mimicry has been characterized as recently as the 1970s as another mechanism by which a pathogen can generate ... Molecular mimicry is, however, only one mechanism by which an autoimmune disease can occur in association with a pathogen. ...
Treated separately is molecular mimicry, which shares some similarity; for instance a virus may mimic the molecular properties ... Aggressive mimicry stands in semantic contrast with defensive mimicry, where it is the prey that acts as a mimic, with ... Included in defensive mimicry is the lesser known Mertensian mimicry, where the mimic is more harmful than the model, and ... Aggressive mimicry is a form of mimicry in which predators, parasites, or parasitoids share similar signals, using a harmless ...
"Advanced research on vasculogenic mimicry in cancer". Journal of Cellular and Molecular Medicine. 19 (2): 315-326. doi:10.1111/ ... Kirschmann, D. A.; Seftor, E. A.; Hardy, K. M.; Seftor, R. E. B.; Hendrix, M. J. C. (April 2012). "Molecular Pathways: ... Vasculogenic mimicry is the formation of microvascular channels by aggressive, metastatic and genetically deregulated tumour ... Milosevic, V., Edelmann, R.J., Fosse, J.H., Östman, A., Akslen, L.A. (2022). Molecular Phenotypes of Endothelial Cells in ...
This phenomenon, known as molecular mimicry, can lead to cross-reactivity, where the immune response to such infections ... "Molecular mimicry and autoimmunity". Journal of Autoimmunity. Elsevier BV. 95: 100-123. doi:10.1016/j.jaut.2018.10.012. ISSN ... Lettre, G.; Rioux, J. D. (2008-10-15). "Autoimmune diseases: insights from genome-wide association studies". Human Molecular ... Therapeutic potential and molecular mechanisms". Biomedicine & Pharmacotherapy. 134: 111157. doi:10.1016/j.biopha.2020.111157. ...
... can also be produced through infection via a mechanism known as molecular mimicry. Upon exposure to ... Poole BD, Scofield RH, Harley JB, James JA (February 2006). "Epstein-Barr virus and molecular mimicry in systemic lupus ... Blank M, Barzilai O, Shoenfeld Y (February 2007). "Molecular mimicry and auto-immunity". Clin Rev Allergy Immunol. 32 (1): 111- ...
The production of this reaction might be due to a form of molecular mimicry, where Borrelia avoids being killed by the immune ... Oldstone MB (October 1998). "Molecular mimicry and immune-mediated diseases". FASEB Journal. 12 (13): 1255-65. doi:10.1096/ ... Bolz DD, Weis JJ (August 2004). "Molecular mimicry to Borrelia burgdorferi: pathway to autoimmunity?". Autoimmunity. 37 (5): ... Auwaerter PG, Aucott J, Dumler JS (January 2004). "Lyme borreliosis (Lyme disease): molecular and cellular pathobiology and ...
... and Molecular Mimicry. pp. 245-254. doi:10.1007/978-1-4612-3734-1_15. ISBN 978-1-4612-8325-6. International Nonproprietary ...
... and Molecular Mimicry. pp. 245-254. doi:10.1007/978-1-4612-3734-1_15. ISBN 978-1-4612-8325-6. v t e v t e (Articles with short ...
It is possible, but uncommon for molecular mimicry to lead to an autoimmune disease. Superantigens are composed of viral or ... Complete clonal deletion can lead to opportunities for molecular mimicry, which has adverse effects for the host. Therefore, ... OCLC 948563239.{{cite book}}: CS1 maint: multiple names: authors list (link) Rose, Noel R. (2015-06-21). "Molecular Mimicry and ...
Other sources suggest a possible origin in molecular mimicry. Mermithid nematodes infect arthropods, residing in their ... Yanoviak, S. P.; Kaspari, M.; Dudley, R.; Poinar, G. (April 2008). "Parasite‐Induced Fruit Mimicry in a Tropical Canopy Ant". ... Tomonaga, K (2004). "Virus-induced neurobehavioral disorders: mechanisms and implications". Trends in Molecular Medicine. 10 (2 ...
Biomimicry Chemical mimicry Locomotor mimicry Mimic octopus Molecular mimicry Preadaptation Semiotics King, R. C.; Stansfield, ... Other forms of mimicry have a reproductive component, such as Vavilovian mimicry involving seeds, vocal mimicry in birds, and ... Mimicry may be to the advantage of both organisms that share a resemblance, in which case it is a form of mutualism; or mimicry ... Mimicry can result in an evolutionary arms race if mimicry negatively affects the model, and the model can evolve a different ...
In RHD, molecular mimicry results in incorrect T cell activation, and these T lymphocytes can go on to activate B cells, which ... Molecular mimicry occurs when epitopes are shared between host antigens and Streptococcus antigens. This causes an autoimmune ... The complicated pathogenesis of RHD is not fully understood, though it has been observed to use molecular mimicry via group A ... Guilherme, L; Kalil, J; Cunningham, M (2006). "Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease". ...
Bridges, C. C.; Zalups, R. K. (2005). "Molecular and ionic mimicry and the transport of toxic metals". Toxicol. Appl. Pharmacol ... and this mimicry leads to many adverse effects. Mercury's neuroplastic mechanisms work by affecting protein production. ...
The molecular mimicry of some LOS molecules is thought to cause autoimmune-based host responses, such as flareups of multiple ... Furthermore, LOS molecules are responsible for the ability of some bacterial strains to display molecular mimicry and antigenic ... Moran AP, Prendergast MM, Appelmelk BJ (1996). "Molecular mimicry of host structures by bacterial lipopolysaccharides and its ... Chastain EM, Miller SD (2012). "Molecular mimicry as an inducing trigger for CNS autoimmune demyelinating disease". Immunol. ...
In 2018, it was demonstrated that T-cells stimulated by Pandemrix were cross-reactive by molecular mimicry with part of the ... "Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy". Proceedings of the National Academy of Sciences ... Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 12: Sleep and Arousal". In Sydor A, Brown RY (eds.). Molecular ... Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York: McGraw-Hill Medical. p. 179. ISBN ...
Moore PS, Boshoff C, Weiss RA, Chang Y (December 1996). "Molecular mimicry of human cytokine and cytokine response pathway ... Molecular Basis of Disease. 1852 (2): 365-78. doi:10.1016/j.bbadis.2014.04.030. PMID 24807060. Chang Y, Cesarman E, Pessin MS, ...
In 2018, it was demonstrated that T-cells stimulated by Pandemrix were cross-reactive by molecular mimicry with part of the ... T-cells stimulated by Pandemrix were cross-reactive by molecular mimicry with the same part of the hypocretin peptide. ... December 2018). "Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy". Proceedings of the National ...
... (also referred to as molecular mimicry) is a type of biological mimicry involving the use of chemicals to dupe ... This form of mimicry is known as Batesian Mimicry. In Batesian mimicry, potential prey organisms will mimic chemicals emitted ... Chemical mimicry exists within many of the different forms of mimicry such as aggressive, protective, Batesian, and Müllerian ... Chemical mimicry exists in many forms and for a variety of uses. It may be classified by the function it performs for the ...
1998). "Molecular mimicry of the inflammation modulatory proteins (IMPs) of poxviruses: evasion of the inflammatory response to ... 1996). "Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV". Science. 274 (5293): 1739-1744. ... Murphy, PM (1994). "Molecular piracy of chemokine receptors by herpesviruses". Infect Agents Dis. 3 (2): 137-164. PMID 7812652 ... Kotwal, GJ (2000). "Poxviral mimicry of complement and chemokine system components: what's the end game?". Immunol Today. 21 (5 ...
The idea of molecular mimicry arose in the context of rheumatic fever, which follows infection with Group A beta-haemolytic ... In contrast to molecular mimicry, the other epitopes need not be structurally similar to the primary one. Epitope modification ... Molecular mimicry - An exogenous antigen may share structural similarities with certain host antigens; thus, any antibody ... Although rheumatic fever has been attributed to molecular mimicry for half a century no antigen has been formally identified ( ...
Other reports point to molecular mimicry between MOG and some viruses as a possible etiology. Demyelinating lesions of MOG- ...
Baron R, Binda C, Tortorici M, McCammon JA, Mattevi A (February 2011). "Molecular mimicry and ligand recognition in binding and ... The reduced FAD state is converted back to its normal resting oxidized state by molecular oxygen with the production of ... June 2010). "The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1". The EMBO ...
Cunningham, Madeleine W. (2 August 2019). "Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group ... molecular mimicry) causing a variety of streptococcal related diseases including Sydenham's chorea but also rheumatic heart ...
Cunningham, Madeleine W. (2019). "Molecular Mimicry, Autoimmunity and Infection: The Cross-reactive Antigens of Group A ... Lichtman, Andrew H.; Pillai, Shiv; Abbas, Abdul K. (2021). "Chapter 16: Immunity to Microbes". Cellular and Molecular ...
August 2019). "Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple ... 2020). "Molecular markers in the CSF proteome differentiate neuroinflammatory diseases". Research Square. doi:10.21203/rs.3.rs- ... It seems that the molecular targets for the OCB's are patient-specific. Inside well defined MS (Lesions disseminated in time ... Later reports point towards a mimicry between ANO-2 and EBV-EBNA-1 protein Anti-NMDAR autoantibodies: There is an overlap ...
A long-standing H. pylori infection may cause gastric autoimmunity by a mechanism known as molecular mimicry. Antibodies ... Molecular dynamics are used in experiments to gain an understanding of the molecular interactions involved in the different ... Molecular Cell Biology. 3 (4): 256-266. doi:10.1038/nrm778. PMID 11994745. S2CID 21893726. Banka S, Ryan K, Thomson W, Newman ... Bunn HF (February 2014). Longo DL (ed.). "Vitamin B12 and pernicious anemia--the dawn of molecular medicine". The New England ...
... molecular mimicry and bystander mechanism. Molecular mimicry refers to an overlap in structural similarity between a viral ... ISBN 978-0-7817-8215-9. Mitchell MG (2010-04-16). Molecular Pathology and the Dynamics of Disease. Academic Press. doi:10.1016/ ... Cann A (2015). Principles of Molecular Virology (6 ed.). Academic Press. ISBN 9780128019559. Flint SJ, Racaniello VR, Rall GF, ... Molecular and Cellular Biology. 8 (10): 4518-23. doi:10.1128/mcb.8.10.4518. PMC 365527. PMID 2903437. Furuya-Kanamori L, Cox M ...
The reason for this is not known; however, molecular mimicry between Mups and structurally similar human lipocalins has been ... Mups are members of a large family of low-molecular weight (~19 kDa) proteins known as lipocalins. They have a characteristic ... Kurtz DT (1981). "Rat alpha 2u globulin is encoded by a multigene family". Journal of Molecular and Applied Genetics. 1 (1): 29 ... Robertson DH, Cox KA, Gaskell SJ, Evershed RP, Beynon RJ (May 1996). "Molecular heterogeneity in the Major Urinary Proteins of ...
Roussel L, Erard M, Cayrol C, Girard JP (October 2008). "Molecular mimicry between IL-33 and KSHV for attachment to chromatin ... July 2003). "Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules ... International Journal of Molecular Sciences. 19 (12): E3956. doi:10.3390/ijms19123956. PMC 6321062. PMID 30544846. Tizard I ( ... International Journal of Molecular Sciences. 19 (10): E2911. doi:10.3390/ijms19102911. PMC 6212888. PMID 30257479. Savenije OE ...
It may also be caused by an immune reaction to a virus (molecular mimicry) or by toxins. The Juvenile Scleroderma Network is an ... Jimenez SA, Derk CT (2004). "Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis ...