Endophytic bacteria in their roots produce maytansine. Currently accepted species include: Putterlickia neglecta Jordaan, R.G.C ...
... (INN), or maytansine (USAN), is a cytotoxic agent. It inhibits the assembly of microtubules by binding to tubulin at ... Lopus, M; Oroudjev, E; Wilson, L; Wilhelm, S; Widdison, W; Chari, R; Jordan, MA (2010). "Maytansine and cellular metabolites of ... Definition of Maytansine Yu, T.-W.; Bai, L; Clade, D; Hoffmann, D; Toelzer, S; Trinh, KQ; Xu, J; Moss, SJ; Leistner, E (2002 ...
... thus is most likely to recognize maytansine or a moiety within the maytansine scaffold. Through transmembrane transport ... A proposed function of SLC46A3 of rising importance is the direct transport of maytansine-based catabolites from the lysosome ... shRNA screens employing two libraries identified SLC46A3 as the only hit as a mediator of noncleavable maytansine-based ADC- ... Among the different types of antibody-drug conjugates (ADCs), maytansine-based noncleavable linker ADC catabolites, such as ...
Definition of Maytansine "International Nonproprietary Names (INN) for pharmaceutical substances: Names for radicals, groups & ...
... maytansine MeSH D09.408.477.497 - mepartricin MeSH D09.408.477.500 - miocamycin MeSH D09.408.477.550 - natamycin MeSH D09.408. ...
... maytansine MeSH D02.540.505.497 - mepartricin MeSH D02.540.505.500 - miocamycin MeSH D02.540.505.550 - natamycin MeSH D02.540. ...
... maytansine MeSH D04.345.295.750 - rifamycins MeSH D04.345.295.750.650 - rifabutin MeSH D04.345.295.750.650.700 - streptovaricin ...