Mitogen-activated protein kinase
Signal transduction MAP kinase kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase MAPK1 (ERK2) MAPK3 (ERK1) MAPK7 ... Similarly, both dual-specificity MAP kinase phosphatases and MAP-specific tyrosine phosphatases bind to MAP kinases through the ... A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine ... MAP Kinase Resource . Table of names for mitogen-activated kinases. MAPK cascade picture Mitogen-Activated+Protein+Kinases at ...
MAP kinase kinase kinase
MAP kinase MAP kinase kinase MAP kinase kinase kinase kinase List of unusual biological names "Global Identification, ... is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently, MAP kinase kinase activates MAP ... These MAP kinases include the extracellular regulated kinases (ERKs), the c-Jun N-terminal Kinases (JNKs), and the p38 MAP ... MAP+Kinase+Kinase+Kinases at the U.S. National Library of Medicine Medical Subject Headings (MeSH) EC 2.7.11.25 Portal: Biology ...
Mitogen-activated protein kinase 9
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple ... MAP Kinase Resource Archived 2021-04-15 at the Wayback Machine. This article incorporates text from the United States National ... Davis RJ (2000). "Signal transduction by the JNK group of MAP kinases". Cell. 103 (2): 239-52. doi:10.1016/S0092-8674(00)00116- ... This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, ...
P38 mitogen-activated protein kinases
MKK3 and SEK activate p38 MAP kinase by phosphorylation at Thr-180 and Tyr-182. Activated p38 MAP kinase has been shown to ... p38 MAP Kinase (MAPK), also called RK or CSBP (Cytokinin Specific Binding Protein), is the mammalian orthologue of the yeast ... Four p38 MAP kinases, p38-α (MAPK14), -β (MAPK11), -γ (MAPK12 / ERK6), and -δ (MAPK13 / SAPK4), have been identified. Similar ... Dusik V, Senthilan PR, Mentzel B, Hartlieb H, Wülbeck C, Yoshii T, Raabe T, Helfrich-Förster C (2014). "The MAP Kinase p38 Is ...
Wall-associated kinase
Kohorn BD, Johansen S, Shishido A, Todorova T, Martinez R, Defeo E, Obregon P (December 2009). "Pectin activation of MAP kinase ... Kohorn BD, Johansen S, Shishido A, Todorova T, Martinez R, Defeo E, Obregon P (December 2009). "Pectin activation of MAP kinase ... Cell wall associated kinases are receptor-like protein kinases, found in plant cell walls, that have the capability to transmit ... Wall-Associated Kinases (WAKs) are a subfamily of receptor-like kinases (RLKs) associated with the cell wall. They were ...
Tyrosine kinase 2
"Identification and chromosomal mapping of new human tyrosine kinase genes". Oncogene. 5 (3): 277-282. PMID 2156206. "Entrez ... This gene encodes a member of the tyrosine kinase and, to be more specific, the Janus kinases (JAKs) protein families. This ... Non-receptor tyrosine-protein kinase TYK2 is an enzyme that in humans is encoded by the TYK2 gene. TYK2 was the first member of ... Tyrosine kinase 2 has been shown to interact with FYN, PTPN6, IFNAR1, Ku80 and GNB2L1. GRCh38: Ensembl release 89: ...
MAPK phosphatase
Kondoh, Kunio; Nishida, Eisuke (1 August 2007). "Regulation of MAP kinases by MAP kinase phosphatases". Biochimica et ... Kondoh, Kunio; Nishida, Eisuke (1 August 2007). "Regulation of MAP kinases by MAP kinase phosphatases". Biochimica et ... Kondoh, Kunio; Nishida, Eisuke (1 August 2007). "Regulation of MAP kinases by MAP kinase phosphatases". Biochimica et ... Kondoh, Kunio; Nishida, Eisuke (1 August 2007). "Regulation of MAP kinases by MAP kinase phosphatases". Biochimica et ...
HER2
Huang YZ, Zang M, Xiong WC, Luo Z, Mei L (January 2003). "Erbin suppresses the MAP kinase pathway". The Journal of Biological ... Signaling pathways activated by HER2 include: mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K/Akt) ... Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ... Peles E, Levy RB, Or E, Ullrich A, Yarden Y (August 1991). "Oncogenic forms of the neu/HER2 tyrosine kinase are permanently ...
Erbin (protein)
Huang YZ, Zang M, Xiong WC, Luo Z, Mei L (January 2003). "Erbin suppresses the MAP kinase pathway". J. Biol. Chem. 278 (2): ... Huang YZ, Zang M, Xiong WC, Luo Z, Mei L (2003). "Erbin suppresses the MAP kinase pathway". J. Biol. Chem. 278 (2): 1108-14. ... Erbin's C-terminal PDZ domain is able to bind to ErbB2, a protein tyrosine kinase which is often associated with poor prognosis ... 281 (2): 927-933. doi:10.1074/jbc.M507360200. PMID 16301319. Favre B, Fontao L, Koster J, Shafaatian R, Jaunin F, Saurat JH, ...
Neuronal memory allocation
When activated by the second messengers such as cAMP and calcium ions, enzymes such as PKA and MAP kinase can translocate to ... Treisman, R. (1996). Regulation of transcription by MAP kinase cascades. Current Opinion in Cell Biology, 8(2), 205-215. Nguyen ... roles for the ERK MAP kinase cascade in memory. Annual Review of Pharmacology and Toxicology, 42(1), 135-163. ... For example, the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) pathways appear to participate in neuronal ...
Activity-regulated cytoskeleton-associated protein
The Arc transcript is dependent upon activation of the mitogen-activated protein kinase or MAP kinase (MAPK) cascade, a pathway ... Impey S, Obrietan K, Storm DR (1999). "Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity". Neuron ... Treisman R (1996). "Regulation of transcription by MAP kinase cascades". Current Opinion in Cell Biology. 8 (2): 205-15. doi: ... mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase ...
Sequestosome 1
Sudo T, Maruyama M, Osada H (2000). "p62 functions as a p38 MAP kinase regulator". Biochem. Biophys. Res. Commun. 269 (2): 521- ... Sanchez P, De Carcer G, Sandoval IV, Moscat J, Diaz-Meco MT (May 1998). "Localization of atypical protein kinase C isoforms ... Sanchez P, De Carcer G, Sandoval IV, Moscat J, Diaz-Meco MT (1998). "Localization of atypical protein kinase C isoforms into ... Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J (March 2001). "The atypical protein kinase C- ...
MAPKAPK5
MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene. The protein encoded by this ... a novel protein kinase regulated by the p38 MAP kinase". EMBO J. 17 (12): 3372-84. doi:10.1093/emboj/17.12.3372. PMC 1170675. ... this kinase is activated through its phosphorylation by MAP kinases, including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta ... activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase". Biochem. Biophys. Res. ...
MAPK4
MAP Kinase Resource Archived 2021-04-15 at the Wayback Machine Portal: Biology v t e (Articles with short description, Short ... Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor ... December 2000). "Arabidopsis map kinase 4 negatively regulates systemic acquired resistance". Cell. 103 (7): 1111-20. doi: ... Gonzalez FA, Raden DL, Rigby MR, Davis RJ (June 1992). "Heterogeneous expression of four MAP kinase isoforms in human tissues ...
MARK2
"Entrez Gene: MARK2 MAP/microtubule affinity-regulating kinase 2". Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, ... Serine/threonine-protein kinase MARK2 is an enzyme that in humans is encoded by the MARK2 gene. EMK (ELKL Motif Kinase) is a ... "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1". EMBO J. 23 (4): 833-43. doi: ... Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT (2001). "PAR-1 is a Dishevelled-associated kinase and a ...
PLA2G4A
1993). "cPLA2 is phosphorylated and activated by MAP kinase". Cell. 72 (2): 269-78. doi:10.1016/0092-8674(93)90666-E. PMID ... 23 (2): 293-301. doi:10.1093/nar/23.2.293. PMC 306668. PMID 7862535. Morri H, Ozaki M, Watanabe Y (1995). "5'-flanking region ... doi:10.1016/0888-7543(95)80093-2. PMID 7782073. Wu T, Ikezono T, Angus CW, Shelhamer JH (1995). "Characterization of the ... 2), induces apoptosis, and potentiates prostaglandin production". Molecular and Cellular Biology. 21 (14): 4470-4481. doi: ...
MARK3
MAP/microtubule affinity-regulating kinase 3 is an enzyme that in humans is encoded by the MARK3 gene. MARK3 has been shown to ... "Entrez Gene: MARK3 MAP/microtubule affinity-regulating kinase 3". Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A ... "The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a ... Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT (2001). "PAR-1 is a Dishevelled-associated kinase and a ...
MAPK7
... is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are ... Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. ... This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the ... MAP Kinase Resource Archived 2021-04-15 at the Wayback Machine. Portal: Biology (Articles with short description, Short ...
MARK1
"Entrez Gene: MARK1 MAP/microtubule affinity-regulating kinase 1". Drewes G, Trinczek B, Illenberger S, et al. (1995). " ... 2005). "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1". EMBO J. 23 (4): 833-43 ... Yang SD, Yu JS, Shiah SG, Huang JJ (1994). "Protein kinase FA/glycogen synthase kinase-3 alpha after heparin potentiation ... 2003). "MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1". EMBO J. 22 (19): 5090-101. doi:10.1093/ ...
MARK4
MAP/microtubule affinity-regulating kinase 4 is an enzyme that in humans is encoded by the MARK4 gene. MARK4 belongs to the ... "Entrez Gene: MARK4 MAP/microtubule affinity-regulating kinase 4". Drewes G, Ebneth A, Preuss U, Mandelkow EM, Mandelkow E ( ... MARK4 kinase has been shown to be involved in microtubule organization in neuronal cells. Levels of MARK4 are elevated in ... Al-Hakim AK, Zagorska A, Chapman L, Deak M, Peggie M, Alessi DR (April 2008). "Control of AMPK-related kinases by USP9X and ...
PEA15
"PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase". Dev. Cell. 1 (2): 239-50. doi:10.1016/s1534-5807(01)00035-1. PMID ... "PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase". Dev. Cell. 1 (2): 239-50. doi:10.1016/S1534-5807(01)00035-1. PMID ... by protein kinase C and calcium/calmodulin kinase II in vitro". J. Neurochem. 71 (3): 1307-14. doi:10.1046/j.1471-4159.1998. ... "Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action". Mol. Cell. Biol. 23 (13): 4511 ...
Casein kinase 2, alpha 1
Yang-Feng TL, Zheng K, Kopatz I, Naiman T, Canaani D (February 1992). "Mapping of the human casein kinase II catalytic subunit ... Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as ... Ahn BH, Kim TH, Bae YS (October 2001). "Mapping of the interaction domain of the protein kinase CKII beta subunit with target ... Allende JE, Allende CC (1995). "Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling ...
MAP3K3
Slattery ML, Lundgreen A, Wolff RK (2012). "MAP kinase genes and colon and rectal cancer". Carcinogenesis. 33 (12): 2398-408. ... Mitogen-activated protein kinase kinase kinase 3 is an enzyme that in humans is encoded by the MAP3K3 gene, which is located on ... "Entrez Gene: MAP3K3 mitogen-activated protein kinase kinase kinase 3". Gilmore PM, McCabe N, Quinn JE, Kennedy RD, Gorski JJ, ... pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative". The Journal of Biological ...
MAPK networks
This immunity requires downstream components via the MAPK cascade to activate the MAP kinases. The flagellin, a peptide of ... Mitogen-activated protein kinase (MAPK) networks are the pathways and signaling of MAPK, which is a protein kinase that ... MAP) Kinase Pathways: Regulation and Physiological Functions1". Endocrine Reviews. 22 (2): 153-183. doi:10.1210/edrv.22.2.0428 ... Mitogen-activated protein kinase (MAPK) networks can be found in eukaryotic cells. MAPK pathways in plants are known to ...
MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene. MNK2 has ... "Entrez Gene: MKNK2 MAP kinase interacting serine/threonine kinase 2". Scheper GC, Parra JL, Wilson M, Van Kollenburg B, ... "The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high ... "The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine ...
Cellular Inhibitor of Apoptosis Protein 1
Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH, Pearson G (April 2001). "Mitogen-activated protein (MAP) ... Ubiquinated RIP1 associates with the prosurvival kinase TAK1. When this complex is deubiquinated apoptosis is induced. The ... kinase pathways: regulation and physiological functions". Endocr. Rev. 22 (2): 153-83. doi:10.1210/edrv.22.2.0428. PMID ... Holcik M, Graber TE (2011). "Distinct roles for the cellular inhibitors of apoptosis proteins 1 and 2". Cell Death & Disease. 2 ...
CLK2
"Chromosomal mapping of three human LAMMER protein-kinase-encoding genes". Human Genetics. 103 (4): 523-4. doi:10.1007/ ... Dual specificity protein kinase CLK2 is an enzyme that in humans is encoded by the CLK2 gene. This gene encodes a member of the ... This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle ... "Entrez Gene: CLK2 CDC-like kinase 2". Human CLK2 genome location and CLK2 gene details page in the UCSC Genome Browser. ...
SLK (gene)
Dan I, Watanabe NM, Kusumi A (May 2001). "The Ste20 group kinases as regulators of MAP kinase cascades". Trends in Cell Biology ... Ste20-like kinases SLK, at the crossroad Al‐Zahrani, Sekhon. "Essential Role for the SLK Protein Kinase in Embryogenesis and ... the most important p21-activated kinase (PAK), germinal center kinases (GCK) and Pleckstrin homology domain containing PAK ( ... "v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II". The Journal of Biological Chemistry. 281 (38 ...
Tropomyosin receptor kinase C
Valent A, Danglot G, Bernheim A (1997). "Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to ... Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, ... The TrkC receptor is part of the large family of receptor tyrosine kinases. A "tyrosine kinase" is an enzyme which is capable ... The TrkC locus encodes at least eight isoforms including forms without the kinase domain or with kinase insertions adjacent to ...
Tropomyosin receptor kinase B
Valent A, Danglot G, Bernheim A (1997). "Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to ... Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or ... The TrkB receptor is part of the large family of receptor tyrosine kinases. A "tyrosine kinase" is an enzyme which is capable ... "The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain". Cell. 61 ...