Liposomes can also be designed to deliver drugs in other ways. Liposomes that contain low (or high) pH can be constructed such ... Another strategy for liposome drug delivery is to target endocytosis events. Liposomes can be made in a particular size range ... Liposomes are used as models for artificial cells. Liposomes can be used on their own or in combination with traditional ... These liposomes may be digested while in the macrophage's phagosome, thus releasing its drug. Liposomes can also be decorated ...

Cationic liposomes are manufactured similarly to liposomes. There are multiple processes that can be used to form cationic ... Cationic liposomes are spherical structures that contain positively charged lipids. Cationic liposomes can vary in size between ... A common application for cationic liposomes is cancer drug delivery. In the 1960s, Alec D. Bangham discovered liposomes as ... The presence of PEG on the surface of the liposome drastically increases the blood circulation time of cationic liposomes. ...

Types of liposome extruders Hand-driven Liposome Extruder Jacketed liposome extruders Online liposome extruders Berger, N; ... The preparation of liposomes results in the formation of the liposome extruder[clarification needed]. A liposome extruder is ... The hand-driven liposome extruders are further categorized into liposome extruders with a thermal-jacketed option and liposome ... Liposome extruders are applied in the formulation of liposomes of homogeneous size distributions. This type of liposome ...

A unilamellar liposome is a spherical liposome, a vesicle, bounded by a single bilayer of an amphiphilic lipid or a mixture of ... Lipid polymorphism Liposome Lipid bilayer Rideau E, Dimova R, Schwille P, Wurm FR, Landfester K (November 2018). "Liposomes and ... small unilamellar liposomes/vesicles (SUVs) that with a size range of 20-100 nm, large unilamellar liposomes/vesicles (LUVs) ... Unilamellar liposomes are used to study biological systems and to mimic cell membranes, and are classified into three groups ...

Ligand-targeted liposomes are used for a variety of applications depending on the liposome, ligand, and liposome contents. ... Ligands can be attached to liposomes through ligation to create ligand-targeted liposomes in a variety of ways. Liposomes have ... Ligand-targeted liposomes can also be used for diagnostics through imaging. The liposomes can contain imaging agents to aid in ... Ligand-targeted liposomes for use in this application use this over-expression to folate and a ligand that targets folate to ...

The Journal of Liposome Research is a peer-reviewed academic journal that publishes original research on the topics of ... liposomes and related systems, lipid-based delivery systems, lipid biology, and both synthetic and physical lipid chemistry. ... the general scope of the journal and abstracts and conference proceedings including those from the International Liposome ...

The liposome encapsulation of vincristine enhances the efficacy of the vincristine drug while simultaneously decreasing the ... Liposome encapsulation increases vincristine's plasma concentration and circulation lifetime in the body, and allows the drug ... "Acrotech Biopharma LLC; Withdrawal of Approval of New Drug Application for MARQIBO (VinCRIStine Sulfate LIPOSOME Injection), 5 ... Silverman JA, Deitcher SR (March 2013). "Marqibo (vincristine sulfate liposome injection) improves the pharmacokinetics and ...

Liposomes are sphere-shaped vesicular structures self-assembled in a solvent composed of a broad type of lipids or other ... The vesicle structure of liposomes improves the effects on drug penetration through biological membranes, which enhance ... "Liposomes in Cosmetics". Journal of Skin and Stem Cell. Retrieved April 29, 2020. Akbarzadeh, Abolfazl; Rezaei-Sadabady, Rogaie ... "Liposome: classification, preparation, and applications". Nanoscale Research Letters. 8 (1): 102. Bibcode:2013NRL.....8..102A. ...

Medical Applications of Liposomes. Elsevier. pp. 165-180. ISBN 978-0-08-053608-8. -; Wasan, Ellen K. (April 5, 2006). " ...

Dietrich Arndt; Reiner Zeisig; Ines Eue & Iduna Fichtner (1995). "Alkylphosphocholines and Alkylphosphocholine Liposomes". ... Journal of Liposome Research. 5 (1): 91-98. doi:10.3109/08982109509039910. Clark, Paul A.; Al-Ahmad, Abraham J.; Qian, ... "Cytotoxic effects of alkylphosphocholines or alkylphosphocholine-liposomes and macrophages on tumor cells". Anticancer Research ...

Liposomes are a common vehicle in drug delivery and specifically for the treatment of cancer. Liposomes contain a phospholipid ... Success with liposomes as drug delivery systems has been shown both in vivo and in vitro. A study by Liu et al. showed that ... In addition, liposomes can entrap hydrophilic molecules in their hydrophilic core. Compared to the common cancer treatment ... investigated the effect of liposome-encapsulated drugs on the efficacy of targeted delivery in SDT. They found that, in ...

Lipoplexes can also be formed from cationic liposomes and DNA solutions, to yield transfection agents. Cationic liposomes cross ... A mechanism for liposome transport across the BBB is lipid-mediated free diffusion, a type of facilitated diffusion, or lipid- ... Liposomes have the potential to protect the drug from degradation, target sites for action, and reduce toxicity and adverse ... Liposomes can also be functionalized by attaching various ligands on the surface to enhance brain-targeted delivery. Another ...

These drug-loaded liposomes travel through the system until they bind at the target site and rupture, releasing the drug. In ... Note- the term "liposome" is in essence synonymous with "vesicle" except that vesicle is a general term for the structure ... The first stealth liposomes were passively targeted at tumor tissues. Because tumors induce rapid and uncontrolled angiogenesis ... The most significant advance in this area was the grafting of polyethylene glycol (PEG) onto the liposome surface to produce " ...

Doxorubicin HCl liposome (Doxil/Caelyx) - PEGylated liposome containing doxorubicin for the treatment of cancer (Alza, 1995) ... Blume G, Cevc, G (13 April 1990). "Liposomes for the sustained drug release in vivo". Biochimica et Biophysica Acta (BBA) - ... Milla, P; Dosio, F (13 January 2012). "PEGylation of proteins and liposomes: a powerful and flexible strategy to improve the ... ISBN 978-0-444-64082-6. OCLC 1127111107.[page needed] Balazs, Daniel A.; Godbey, WT (15 December 2011). "Liposomes for Use in ...

... large unilamellar liposomes/vesicles (LUVs) with a size range of 100-1000 nm and giant unilamellar liposomes/vesicles (GUVs) ... the vesicles are called unilamellar liposomes; otherwise they are called multilamellar liposomes. The membrane enclosing the ... Alternatively, they may be prepared artificially, in which case they are called liposomes (not to be confused with lysosomes). ... Artificial vesicles are classified into three groups based on their size: small unilamellar liposomes/vesicles (SUVs) with a ...

Zhang, Zhenhai; Li, Zhifei; Yu, Wei; Li, Kejie; Xie, Zhihong; Shi, Zhiguo (2013). "Propulsion of liposomes using bacterial ... encapsulated liposome with targeting bacteria (Salmonella Typhimurium)". Sensors and Actuators B: Chemical. 224: 217-224. doi: ...

Ottova-Leitmannova, A. (2006). Advances in Planar Lipid Bilayers and Liposomes. Academic Press. v t e (Articles with short ...

As of 2016[update] a few have been approved.[citation needed] Immunoliposomes are antibody-conjugated liposomes. Liposomes can ...

Liposome formulations encapsulate anti-cancer drugs for selective uptake to tumors via the EPR effect. They are included Doxil ... These efforts include protein capsids and liposomes. However, as some important, normal tissues, such as the liver and kidneys ... "The mechanism of liposome accumulation in infarction". Biochimica et Biophysica Acta (BBA) - General Subjects. 797 (3): 363-8. ... "Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence ...

Osawa M, Anderson DE, Erickson HP (May 2008). "Reconstitution of contractile FtsZ rings in liposomes". Science. 320 (5877): 792 ... showing the protein's contractile force on liposomes with no other proteins present. Erickson (2009) proposed how the roles of ...

Surolia, Bachhawat B. K.; Podder S. K. (1975). "Interaction between lectin from Ricinus communis and liposome containing ... Mumtaz, Ghosh C.; Bachhawat B. K. (1991). "Design of liposomes for circumventing the reticuloendothelial cells". Glycobiology. ... a hereditary disease of the brain His studies on sugar-bearing liposomes led to its use as a carrier for in situ delivery of ... using sugar-bearing liposomes. He also worked on the therapy of systemic fungal infections by developing liposomal formulations ...

He is best known for his research on liposomes. He was married to Rosalind; they had four children and eleven grandchildren. ... Deamer, David A. (1 May 2010). "From "Banghasomes" to liposomes: A memoir of Alec Bangham, 1921-2010". The FASEB Journal. 24 (5 ... "Alec Bangham - 'father of liposomes' - dies aged 88". Archived from the original on 29 September 2011. Retrieved 31 August 2011 ... was a British biophysicist who first studied blood clotting mechanisms but became well known for his research on liposomes and ...

Liposome-encapsulated mRNA encoding a viral antigen was shown in 1993 to stimulate T cells in mice. The following year self- ... July 1993). "Induction of virus-specific cytotoxic T lymphocytes in vivo by liposome-entrapped mRNA". European Journal of ... "Cationic liposome-mediated RNA transfection". Proceedings of the National Academy of Sciences of the United States of America. ...

Ellens, H; Bentz, J; Szoka, FC (1985). "H+- and Ca2+-induced fusion and destabilization of liposomes". Biochemistry. 24 (13): ... 4 April 2022). "Single-particle combinatorial multiplexed liposome fusion mediated by DNA". Nat. Chem. 14 (5): 558-565. Bibcode ... "A DNA-Programmed Liposome Fusion Cascade". Angewandte Chemie International Edition. 56 (43): 13228-13231. doi:10.1002/anie. ... "Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes". ACS Central Science. 2 (9): 621-630. doi:10.1021/ ...

MacKay, J. Andrew; Deen, Dennis F.; Szoka, Francis C. (February 2005). "Distribution in brain of liposomes after convection ... There are several types of microcarriers which have been used for CED, including nanospheres, nanoparticles, liposomes, ...

... and Liposomes combined with immunostimulatory molecules (e.g. AS01B). Delivery systems are primarily divided into polymer-based ... Vaccine antigens are often encapsulated within microspheres or liposomes. Common microspheres made using Poly-lactic acid (PLA ... and poly-lactic-co-glycolic acid (PLGA) allow for controlled antigen release by degrading in vivo while liposomes including ... delivery systems (microspheres and liposomes) and live delivery systems (gram-positive bacteria, gram-negative bacteria and ...

Movassaghian, S; Moghimi, HR; Shirazi, FH; Torchilin, VP (Dec 2011). "Dendrosome-dendriplex inside liposomes: as a gene ...

Liposomes are made up of phospholipids forming spherical vesicles. This property enables liposomes to exhibit high ... Liposomes, solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), and nanoemulsions are examples. ... Studies report potential application of liposomes to treat brain diseases due to increased retention and absorption in nasal ... A previous study developed a cationic liposome loaded with mRNA and green fluorescent protein (GFP). Intranasal delivery of ...

El Maghraby, G. M.; Barry, B. W.; Williams, A. C. (2008-08-07). "Liposomes and skin: From drug delivery to model membranes". ... Other vesicular systems, such as liposomes and ethosomes, have already been extensively researched and utilized as drug ... "Elastic and Ultradeformable Liposomes for Transdermal Delivery of Active Pharmaceutical Ingredients (APIs)". International ...

... working on Liposomes as immunomodulators and drug delivery using Liposomes and he secured a PhD degree for his thesis, ... Immunogenicity of carbohydrate determinants mediated through Liposomes: Liposome-mediated drug delivery from the Calcutta ... Debi P Sarkar; Komal Ramani; Sandeep K Tyagi (2002). "Targeted Gene Delivery by Virosomes". Liposome Methods and Protocols: 163 ...

Nanomedicine, the general field Micelle, lipid cored Liposome, lipid bilayer shell, an earlier form with some limitations ... Lasic, Danilo D. (1997). Liposomes in Gene Delivery. Boca Raton: CRC Press. p. 191. ISBN 9780849331091. Retrieved 11 January ... In addition, polymeric nanoparticles, self-emulsifying delivery systems, liposomes, microemulsions, micellar solutions and ...

Palchetti, S.; Colapicchioni, V.; Digiacomo, L (2016). "The protein corona of circulating PEGylated liposomes". Biochim Biophys ...

Bicelles are much smaller than liposomes, and so can be used in experiments such as NMR spectroscopy where the larger vesicles ... F Szoka and D Papahadjopoulos."Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)." Annual Review ... "Quantifying the effects of melittin on liposomes". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1768 (1): 13-20. doi: ... is achieved by exposure of the lipid coated gold substrate to outer layer lipids either in an ethanol solution or in liposomes ...

"Preparation and characterization of glycolipid-bearing multilamellar and unilamellar liposomes". Liposome Methods and Protocols ... the role of glycosphingolipids as biological receptors through studies on lectin-glycolipid interactions using liposomes. He ...

Sendai virus-induced agglutination of liposomes containing glycophorin". Biochimica et Biophysica Acta (BBA) - Biomembranes. ... F protein is responsible for this induction because reconstituted liposomes containing F protein can stimulate IL-6 production ... F protein is responsible for this induction because reconstituted liposomes containing F protein can stimulate IL-6 production ... "Membrane penetration of Sendai virus glycoproteins during the early stages of fusion with liposomes as determined by ...

Robert Malone; Philip L. Felgner; Inder Verma (August 1, 1989). "Cationic liposome-mediated RNA transfection". Proceedings of ... discovering in what Nature has described as a landmark experiment that it was possible to transfer mRNA protected by a liposome ...