A similar increase in lipid mobilization was observed. Conversely, cockroach AKH led to similar activity within a locust. AKH ... Lipids are transported from the hemolymph and metabolized by flight muscle in order to maintain flight. However, a high ... concentration of lipids remains in the hemolymph, implying that an agent may be responsible for activating lipid transport into ... Adipokinetic hormones (AKHs) are metabolic neuropeptides, mediating mobilization of energy substrates in many insects. An ...
"Plasma FGF21 is elevated by the intense lipid mobilization of lactation". Endocrinology. 152 (12): 4652-61. doi:10.1210/en.2011 ... Treatment with LLF580 had beneficial effects on serum lipids, liver fat, and biomarkers of liver injury; with mild to moderate ... FGF21 is beneficially involved in the regulation of lipid, glucose, and energy metabolism. It can be synthesized in several ... Treatment of mice with FGF21 results in increased energy expenditure, fat utilization and lipid excretion. Shahror et al. found ...
Escher CL, Widmer F (1997). "Lipid mobilization and gluconeogenesis in plants: do glyoxylate cycle enzyme activities constitute ...
Andarwulan N, Fardiaz D, Wattimena GA, Shetty K (1999). "Antioxidant activity associated with lipid and phenolic mobilization ...
"Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation". ... CMA degrades lipid droplet proteins (perilipin 2 and perilipin 3). Removal of these lipid droplet coat proteins by CMA precedes ... Degradation of LAMP-2A monomers at the lysosomal membrane occurs in discrete cholesterol-rich lipid microdomains of the ... Proteomics analyses identified several enzymes of the carbohydrate and the lipid metabolism pathways to be CMA substrates, and ...
"The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics ... that receptor-activated hydrolysis of PIP2 produced a molecule that caused increases in intracellular calcium mobilization. ...
June 2020). "Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical ... ATGL is also the key enzyme that would be able to maintain a balance between mobilization and lipid storage. Lipolytic ... Smirnova E, Goldberg EB, Makarova KS, Lin L, Brown WJ, Jackson CL (January 2006). "ATGL has a key role in lipid droplet/ ... Lipid Droplets. Academic Press. 116: 83-105. doi:10.1016/b978-0-12-408051-5.00006-1. ISBN 9780124080515. PMC 4529287. PMID ...
Their laboratory has shown that mutation in PNPLA3 causes accumulation of PNPLA3 on lipid droplets, which compromises the ... mobilization of triglycerides from liver cells. She sits on the Board of Directors at Pfizer. Hobbs graduated from Stanford ...
Mobilization of lipid stores have been indicated by the inverse relationship between cortisol levels and fat free mass (FFM): ... Women with FHA caused by exercised-induced factors tend to have a higher lipid profile. As is expected from the presence of ... and lipid profiles. It has been hypothesized that premenopausal hypoestrogenemia caused by ovarian disruption, including that ... "Amenorrhea in female athletes is associated with endothelial dysfunction and unfavorable lipid profile". The Journal of ...
... lipid mobilization MeSH G06.535.710.690 - protein carbonylation MeSH G06.535.723.110 - anaerobic threshold MeSH G06.535.723.620 ... lipid peroxidation MeSH G06.535.335.631 - oxidative phosphorylation MeSH G06.535.335.693 - pentose phosphate pathway MeSH ...
Mobilization and cellular uptake of stored fats and triacylglycerol (with Animation) Bozza, PT; Viola, JP (Apr-Jun 2010). " ... Lipid droplets, also referred to as lipid bodies, oil bodies or adiposomes, are lipid-rich cellular organelles that regulate ... In non-adipocytes, lipid storage, lipid droplet synthesis and lipid droplet growth can be induced by various stimuli including ... but since the discovery in the 1990s of proteins in the lipid droplet coat that regulate lipid droplet dynamics and lipid ...
The shift from preferential lipid synthesis and fat storage, to the mobilization of fat (in the form of free fatty acids), ...
The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis". Journal ... Phosphorylation of perilipin is essential for the mobilization of fats in adipose tissue. Perilipin is part of a gene family ... The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis". Journal ... an ancient family of lipid droplet proteins that regulate cellular lipid stores". Biochimica et Biophysica Acta (BBA) - ...
... a sphingolipid derived from ceramide that is a potent messenger molecule involved in regulating calcium mobilization, cell ... Solid lipid nanoparticle - Novel drug delivery system Simple lipid Emulsion test Lipid microdomain Membrane lipid - Lipid ... Introductory List of lipid-related web sites Nature Lipidomics Gateway - Round-up and summaries of recent lipid research Lipid ... The process of lipid metabolism synthesizes and degrades the lipid stores and produces the structural and functional lipids ...
Meanwhile AKH/Corazonin Peptide (ACP) does not mobilize (or inhibit mobilization) of either. Mugumbate et al., 2013 provides in ... gambiae adipokinetic hormone (AKH) mobilizes carbohydrates but not lipids. ...
... and transfer the retinol-RBP4 to HSCs for storage in lipid droplets as retinyl esters. Mobilization reverses the process: ... Storage of retinol is in lipid droplets in the liver. A high capacity for long-term storage of retinol means that well- ... Hepatocytes take up the lipid-rich chylomicrons, bind retinol to retinol-binding protein 4 (RBP4), ...
The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis". Journal ... the more than 50-fold increase in fat mobilization (triggered by epinephrine) is primarily due to perilipin phosphorylation. ... PLIN4 coats lipid droplets in adipocytes to protect them from lipases. The PLIN4 gene may be associated with insulin resistance ... PLIN4 is a member of the perilipin family, a group of proteins that coat lipid droplets in adipocytes, the adipose tissue cells ...
LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). This gene encodes a ... "Lysophosphatidic acid induces human natural killer cell chemotaxis and intracellular calcium mobilization". Eur. J. Immunol. 33 ... functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This ...
LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA). This gene encodes a ... This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular ... 2001). "Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production. Potential ... "Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization". Mol. Pharmacol ...
Other Lipid Mediators. 89 (3-4): 82-8. doi:10.1016/j.prostaglandins.2009.05.003. PMID 19460454. Al Mahri S, Malik SS, Al ... made to express Gly180Ser FFAR1 using transfection methods had significantly lower calcium mobilization responses to oleic acid ... and its carriers showed reduced plasma insulin responses to an oral lipid challenge. Studies on HeLa cells (i.e., cells derived ... of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization". The ...
MLN64 mediates mobilization of lysosomal cholesterol to steroidogenic mitochondria. J Biol Chem 277: 33300-33310 [PubMed] doi: ... StAR related lipid transfer domain containing 3 (STARD3) is a protein that in humans is encoded by the STARD3 gene. STARD3 also ... This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic ... "Entrez Gene: StAR related lipid transfer domain containing 3". Retrieved 2018-08-07. Alpy F, Tomasetto C (June 2006). "MLN64 ...
This then results in increased iron absorption from the intestine and mobilization of iron from stores, which can then be used ... This sequence had previously been found expressed in mouse skeletal muscle, called myonectin (CTRP15), and linked to lipid ... In its role as myonectin, it also promotes lipid uptake into adipocytes and hepatocytes. Synthesis of erythroferrone is ... "Myonectin (CTRP15), a Novel Myokine That Links Skeletal Muscle to Systemic Lipid Homeostasis." THE JOURNAL OF BIOLOGICAL ...
This triggers them to "spread out" and allow for HSL to enter the lipid droplet. Activation of partially purified HSL requires ... doi:10.1016/B978-0-08-091283-7.00110-7. ISBN 978-0-08-091283-7. Mehta S (October 2013). "Mobilization and Cellular Uptake of ... Shen WJ, Sridhar K, Bernlohr DA, Kraemer FB (May 1999). "Interaction of rat hormone-sensitive lipase with adipocyte lipid- ... In addition to phosphorylating HSL, PKA phosphorylates perilipins on the surface of lipid droplets within adipose cells. ...
... lipid-modifying effects or side effects as niacin, i.e., when niacin takes on the -amide group, it does not reduce cholesterol ... are utilized in transfer reactions within DNA repair and calcium mobilization. NAD also plays a critical role in human ... "Supports a healthy blood lipid profile." The American Heart Association (AHA) strongly advises against the use of non- ...
The biosynthesis of OEA and other bioactive lipid amides is modulated by bile acids. OEA has been demonstrated to bind to the ... "Postprandial increase of oleoylethanolamine mobilization in small intestine of the Burmese python (Python molurus)". Am J ... It is a naturally occurring ethanolamide lipid that regulates feeding and body weight in vertebrates ranging from mice to ... Gaetani S, Oveisi F, Piomelli D (2003). "Modulation of meal pattern in the rat by the anorexic lipid mediator ...
Graham, Ian A. (2008). "Seed Storage Oil Mobilization". Annual Review of Plant Biology. 59 (1): 115-142. doi:10.1146/annurev. ... "Acyl-Lipid Metabolism". The Arabidopsis Book. 11: e0161. doi:10.1199/tab.0161. PMC 3244904. PMID 22303259. Eastmond, Peter J.; ... dissect the main metabolic pathways controlling oil mobilisation in Arabidopsis seed and provided new insight into how a lipid ...
Through this process, lipid droplets accumulate in the adipocyte. However, preadipocytes cell lines have difficult to different ... The hormone insulin promotes expansion whereas the counter hormones epinephrine, glucagon, and ACTH promote mobilization. ... Green H, Kehinde O (28 February 1974). "Sublines of mouse 3T3 cells that accumulate lipid". Cell. 1 (3): 113-116. doi:10.1016/ ... Tontonoz P, Hu E, Spiegelman BM (December 1994). "Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated ...
May 2009). "Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay". The Journal of ... DPI was further characterized to activate several GPR3-mediated signal transduction pathways, including Ca(2+) mobilization, ... The molecule Sphingosine 1-phosphate (S1P) is a signaling lipid that exists in the extracellular plasma, its synthesis is ... Exposure to environmental cold stimulates thermogenic catabolism of lipids and carbohydrates in brown adipose tissue (BAT). BAT ...
Müller G, Schulz A, Wied S, Frick W (Mar 2005). "Regulation of lipid raft proteins by glimepiride- and insulin-induced ... These kinases provide activation signals, which play critical roles in proliferation, Ca2+ mobilization and cell ... The insulin secretagogue, glimepiride (Amaryl®) activates Lyn in adipocytes via the disruption of lipid rafts. This indirect ... "Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex". Immunity. 13 (2): 243- ...
Effects of partial sugar deprivation on lifespan and carbohydrate mobilization in the parasitoid Macrocentrus grandii ( ... Effects of sugar feeding on carbohydrate and lipid metabolism in a parasitoid wasp. Physiological Entomology, 25(1), 17-26. ( ...