The Friend virus (FV) is a strain of murine leukemia virus. The Friend virus has been used for both immunotherapy and vaccines ... The murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in murine (mouse) hosts. ... The murine leukemia viruses are group/type VI retroviruses belonging to the gammaretroviral genus of the Retroviridae family. ... Rein A (2011). "Murine leukemia viruses: objects and organisms". Advances in Virology. 2011: 403419. doi:10.1155/2011/403419. ...
A highly efficient helper virus commonly used when growing A-MuLV in vitro is Moloney murine leukemia virus (M-MuLV). It causes ... Shields A, Rosenberg N, Baltimore D (1979). "Virus production by Abelson murine leukemia virus-transformed lymphoid cells". J. ... The Abelson murine leukemia virus (Ab-MLV or A-MuLV) is a retrovirus (Class VI) used to induce malignant transformation of ... The Abelson murine leukemia virus is named for the American pediatrician Herbert T. Abelson, who together with Louise S ...
"Xenotropic Murine Leukemia Virus-Related Virus (XMRV) and other Polytropic Murine Leukemia Viruses (pMLV)" (PDF). AABB. October ... Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus". mBio. 3 (5): ... Xenotropic murine leukemia virus-related virus (XMRV) is a retrovirus which was first described in 2006 as an apparently novel ... "XMRV (Xenotropic Murine Leukemia Virus-related Virus) , CDC". Centers for Disease Control. Archived from the original on 18 ...
"Properties of a murine sarcoma virus". Bibliotheca Haematologica. International Symposium on Comparative Leukemia Research. 36 ... The first two Ras genes, HRAS and KRAS, were identified from studies of two cancer-causing viruses, the Harvey sarcoma virus ... "Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses". Proceedings of ... "A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus". ...
over 1300 citations) Hartley, J. W.; Wolford, N. K.; Old, L. J.; Rowe, W. P. (1977). "A new class of murine leukemia virus ... over 800 citations) Lowy, D. R.; Rowe, W. P.; Teich, N.; Hartley, J. W. (1971). "Murine Leukemia Virus: High-Frequency ... over 700 citations) Staal, S. P.; Hartley, J. W.; Rowe, W. P. (1977). "Isolation of transforming murine leukemia viruses from ... Rowe, Wallace P.; Pugh, Wendell E.; Hartley, Janet W. (1970). "Plaque assay techniques for murine leukemia viruses". Virology. ...
March 2012). "Detection of murine leukemia virus in the Epstein-Barr virus-positive human B-cell line JY, using a computational ... JY cells are positive for murine leukemia virus. "ECACC HLA-Typed Collection: JY". Public Health England. Retrieved 28 June ... Cell report for JY at IMGT/HLA Cellosaurus entry for JY v t e (Human cell lines, Epstein-Barr virus, All stub articles, Cell ... The JY cell line is an Epstein-Barr virus (EBV)-immortalised B cell lymphoblastoid line. JY cells express HLA class-I A2 and ...
"Host cell cathepsins potentiate Moloney murine leukemia virus infection". Journal of Virology. 81 (19): 10506-14. doi:10.1128/ ...
II.-Inhibition of dna-polymerase from murine sarcoma leukemia virus". Biochimie. 58 (6): 689-95. doi:10.1016/s0300-9084(76) ...
De Tkaczevski, L; De Harven, E; Friend, C (1968). "Structure and leukemogenic activity of a murine leukemia virus". Journal of ... He did pioneering research on viruses, mostly related to murine leukemia. He is former President of the Electron Microscopy ... De Harven, E; Friend, C (1966). "Origin of the viremia in murine leukemia". National Cancer Institute Monograph. 22: 79-105. ... Tumour Viruses of Murine Origin. Novartis Foundation Symposia. pp. 193-213. doi:10.1002/9780470719275.ch10. ISBN 978-0-470- ...
Yap MW, Nisole S, Lynch C, Stoye JP (July 2004). "Trim5alpha protein restricts both HIV-1 and murine leukemia virus". ...
"Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection". Journal of Virology. 90 (15): 6896-6905. doi: ... Not much is known about virus' motor-specific binding sites, but it is known that some viruses contain proline-rich sequences ( ... Dynein and kinesin can both be exploited by viruses to mediate the viral replication process. Many viruses use the microtubule ... that diverge between viruses) which, when removed, reduces dynactin binding, axon transport (in culture), and neuroinvasion in ...
Human immunodeficiency virus type 1 and Moloney murine leukemia virus enzymes prefer to cleave the RNA strand one nucleotide ... "Crystal structure of the moloney murine leukemia virus RNase H domain". Journal of Virology. 80 (17): 8379-89. doi:10.1128/jvi. ... Taylor JM (March 1977). "An analysis of the role of tRNA species as primers for the transcription into DNA of RNA tumor virus ... Leo B, Schweimer K, Rösch P, Hartl MJ, Wöhrl BM (September 2012). "The solution structure of the prototype foamy virus RNase H ...
... the human version of TRIM5α can inhibit strains of the murine leukemia virus (MLV) as well as equine infectious anemia virus ( ... Yap MW, Nisole S, Lynch C, Stoye JP (2004). "Trim5α protein restricts both HIV-1 and murine leukemia virus". Proc. Natl. Acad. ... The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses (that is viruses ... By using a PtERV1 capsid, which produces higher titer virus-like particles, Perez-Caballero et al. reported that PtERV1 is not ...
Coffin, JM; Hageman RC; Maxam AM; Haseltine WA (1978). "Structure of the Genome of Moloney Murine Leukemia Virus: A Terminally ... "Gibbon Ape Leukemia Virus Hall's Island: New Strain of Gibbon Ape Leukemia Virus". Journal of Virology. 29 (1): 395-400. doi: ... "Construction of Recombinant Retroviruses that Express the Human T Cell Leukemia Virus Type II and Human T Cell Leukemia Virus ... Rosen, CR; Haseltine WA; Lenz J; Ruprecht R; Cloyd M (1985). "Tissue Selectivity of Murine Leukemia Virus (MULV) Infection is ...
"President's Cancer Panel". Witte ON, Dasgupta A, Baltimore D (February 28, 1980). "Abelson murine leukemia virus protein is ... Konopka JB, Watanabe SM, Witte ON (July 1984). "An alteration of the human c-abl protein in K562 leukemia cells unmasks ... Witte's research has contributed to the understanding of human leukemias, immune disorders and stem cell activity in cancers of ... This finding influenced the development of targeted drugs like Ibrutinib to treat leukemia and lymphoma. Witte's current ...
His dissertation described the biosynthesis of Rauscher murine leukemia virus reverse transcriptase. From 1980 to 1982, he ...
"Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase". Virus Research. 134 (1-2 ... Retroviral RT proteins from HIV-1 and murine leukemia virus are the best-studied members of the family. Retroviral RT is ... Pathogenic examples include human immunodeficiency virus and hepatitis B virus, respectively. Both encode large multifunctional ... "Insight into the mechanism of the stabilization of moloney murine leukaemia virus reverse transcriptase by eliminating RNase H ...
A few examples of the virus are Moloney murine leukemia virus, xenotropic MuLB-related virus, feline leukemia virus, and feline ... Example species are the murine leukemia virus and the feline leukemia virus. They cause various sarcomas, leukemias and immune ... over 50 human cancer cell lines that were claimed to be linked to murine leukemia virus-related virus or murine leukemia virus ... A specific gammaretrovirus called xenotropic murine leukemia virus-related virus (XMRV) has been found to infect prostate ...
Jainchill JL, Aaronson SA, Todaro GJ (November 1969). "Murine sarcoma and leukemia viruses: assay using clonal lines of contact ...
The virus used in the experiment was a mouse-tropic strain of Murine leukemia virus isolated from the brain of a mouse captured ... Hartley, JW; Rowe, WP (July 1976). "Naturally occurring murine leukemia viruses in wild mice: characterization of a new " ... Langdon WY, Hartley JW, Klinken SP, Ruscetti SK, Morse HC (1989). "v-cbl, an oncogene from a dual-recombinant murine retrovirus ... Leukemia. 13 (5): 760-7. doi:10.1038/sj/leu/2401397. PMID 10374881. Watanabe S, Take H, Takeda K, Yu ZX, Iwata N, Kajigaya S ( ...
Johnson AD, Cohn CS (October 2016). "Xenotropic Murine Leukemia Virus-Related Virus (XMRV) and the Safety of the Blood Supply ... "Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: ... "Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome". Retrovirology. 7 (1 ... Studies eventually concluded that neither people nor the blood supply had been infected with the XMRV virus, and the origin of ...
Murine leukemia viruses (MLVs) were among the first to be investigated for their use in gene therapy. However, recent research ... and Tumor-Specific Targeting of Murine Leukemia Virus-Based Replication-Competent Retroviral Vectors". Journal of Virology. 80 ... Many such viruses have been the basis of research using viruses in gene therapy, but the lentivirus is unique in its ability to ... Because the virus has been adapted to lose most of its genome, the virus becomes safer and more effective in transplanting the ...
For the virus to penetrate the cytosol of a host cell, a low pH is necessary. The env gene of Murine Leukemia Virus (MLV) codes ... The Env proteins of the Avian Sarcoma and Leukosis virus (ASLV) and the Murine Leukemia Virus (MLV) are both trimers of SU-TM ... This membrane receptor was isolated from Rauscher murine leukemia virus (R-MuLV). The retroviral protein env has been captured ... DeLarco J, Todaro GJ (July 1976). "Membrane receptors for murine leukemia viruses: characterization using the purified viral ...
"NMR structure of the 101-nucleotide core encapsidation signal of the Moloney murine leukemia virus". J Mol Biol. 337 (2): 427- ... D'Souza V, Summers MF (2004). "Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus". Nature. ... signal is an RNA element known to be essential for stable dimerisation and efficient genome packaging during virus assembly. ...
Staal SP, Hartley JW, Rowe WP (July 1977). "Isolation of transforming murine leukemia viruses from mice with a high incidence ... This virus was named Akt-8, the "t" representing its transforming capabilities. AKT1 has been shown to interact with: AKTIP, ... "Entrez Gene: AKT1 v-akt murine thymoma viral oncogene homolog 1". Lindhurst MJ, Sapp JC, Teer JK, Johnston JJ, Finn EM, Peters ... Pekarsky Y, Hallas C, Croce CM (2001). "Molecular basis of mature T-cell leukemia". JAMA. 286 (18): 2308-14. doi:10.1001/jama. ...
Staal SP, Hartley JW, Rowe WP (July 1977). "Isolation of transforming murine leukemia viruses from mice with a high incidence ... the virus activates Akt1, which in turn causes the release of calcium. Treating the cells with Akt inhibitors before virus ... C. P. Rhoads by K. B. Rhoads at the Rockefeller Institute." When the oncogene encoded in this virus was discovered, it was ... Akt1 is now thought to be the "key" for cell entry by HSV-1 and HSV-2 (herpes virus: oral and genital, respectively). ...
Doehle BP, Schäfer A, Wiegand HL, Bogerd HP, Cullen BR (July 2005). "Differential sensitivity of murine leukemia virus to ... "Vif Proteins from Diverse Human Immunodeficiency Virus/Simian Immunodeficiency Virus Lineages Have Distinct Binding Sites in ... A3C was also shown to inhibit other viruses. This gene is a member of the cytidine deaminase gene family. It is one of seven ... Baumert TF, Rösler C, Malim MH, von Weizsäcker F (September 2007). "Hepatitis B virus DNA is subject to extensive editing by ...
... and the 1950s discoveries of Gross murine leukemia virus and polyoma virus". Studies in History and Philosophy of Science Part ... Murine polyomavirus and its close relative hamster polyomavirus are historically the only two known viruses whose genomes ... "Gangliosides are receptors for murine polyoma virus and SV40". The EMBO Journal. 22 (17): 4346-55. doi:10.1093/emboj/cdg439. ... 107-9 Although viruses in circulation among feral mice can be tumorigenic, under natural conditions the virus does not cause ...
"The receptors for gibbon ape leukemia virus and amphotropic murine leukemia virus are not downregulated in productively ... "Gibbon ape leukemia virus-Hall's Island: new strain of gibbon ape leukemia virus". Journal of Virology. 29 (1): 395-400. doi: ... The earliest retroviral vectors were based on the Moloney murine leukemia virus (MMLV) which when pseudotyped with GaLV ... J, McKee; N, Clark; F, Shapter; G, Simmons (April 2017). "A New Look at the Origins of Gibbon Ape Leukemia Virus". Virus Genes ...
Garcia JV, Jones C, Miller AD (1991). "Localization of the amphotropic murine leukemia virus receptor gene to the ... 1994). "A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family". Proc. ... Kozak SL, Siess DC, Kavanaugh MP, Miller AD, Kabat D (Jun 1995). "The envelope glycoprotein of an amphotropic murine retrovirus ...