... belongs to a family of plasma membrane proteins that mediate transport of sugars across the membrane by facilitative ... Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11) also known as glucose transporter type 10/11 (GLUT ... "A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical ... "Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of ...
Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the ... Phay JE, Hussain HB, Moley JF (Aug 2000). "Cloning and expression analysis of a novel member of the facilitative glucose ... Shikhman AR, Brinson DC, Valbracht J, Lotz MK (2001). "Cytokine regulation of facilitated glucose transport in human articular ... Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene. ...
... facilitates the transport of glucose across the plasma membranes of mammalian cells. This gene encodes a facilitative ... Bunn RC, Jensen MA, Reed BC (April 1999). "Protein interactions with the glucose transporter binding protein GLUT1CBP that ... GLUT1 55-kDa is present in the endothelial cells of the brain vasculature and is responsible for glucose transport across the ... This protein lacks a signal sequence; its C-terminus, N-terminus, and the very hydrophilic domain in the protein's center are ...
... the sodium-glucose cotransporter. Glucose+Transport+Proteins,+Facilitative at the U.S. National Library of Medicine Medical ... Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose across the plasma membrane ... In Saccharomyces cerevisiae glucose transport takes place through facilitated diffusion. The transport proteins are mainly from ... GLUT proteins transport glucose and related hexoses according to a model of alternate conformation, which predicts that the ...
These uncharacterized membrane proteins were assayed for glucose transport ability by expression in HEK293T (human embryonic ... Takanaga H, Frommer WB (August 2010). "Facilitative plasma membrane transporters function during ER transit". FASEB Journal. 24 ... Solute carrier family TOG Superfamily Transporter Classification Database Glucose transporter Transport protein Saier, MH Jr. " ... which have negligible glucose transport ability in the normal state. These membrane proteins were co-expressed with a ...
GLUT-1 acts as a facilitative transporter of glucose, transporter glucose along its concentration gradient. When glucose binds ... The galactose permease or GalP found in Escherichia coli is an integral membrane protein involved in the transport of ... Transmembrane protein List of proteins (Integral membrane proteins, Bacterial proteins). ... Olson, A.L., and Pessin, J.E. (1996). Structure, function, and regulation of the mammalian facilitative glucose transporter ...
The SLC group include examples of transport proteins that are: facilitative transporters (allow solutes to flow downhill with ... Wright EM, Turk E (February 2004). "The sodium/glucose cotransport family SLC5". Pflügers Archiv. 447 (5): 510-518. doi:10.1007 ... fatty acid transport proteins (SLC27A1, SLC27A2, SLC27A3, SLC27A4, SLC27A5, SLC27A6) Na+-coupled nucleoside transport (SLC28A1 ... The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members ...
It is associated with GLUT2, a glucose transport protein which, when functioning normally, allows glucose to exit several ... Santer R, Steinmann B, Schaub J (March 2002). "Fanconi-Bickel syndrome--a congenital defect of facilitative glucose transport ... January 2002). "The mutation spectrum of the facilitative glucose transporter gene SLC2A2 (GLUT2) in patients with Fanconi- ... The syndrome results in hepatomegaly secondary to glycogen accumulation, glucose and galactose intolerance, fasting ...
For example, GLUT1 is a named carrier protein found in almost all animal cell membranes that transports glucose across the ... The solute carriers and atypical SLCs are secondary active or facilitative transporters in humans. Collectively membrane ... Often these redox proteins are not considered transport proteins. Every carrier protein, especially within the same cell ... Unlike channel proteins which only transport substances through membranes passively, carrier proteins can transport ions and ...
... facilitated glucose transporter member 12 is a protein that in humans is encoded by the SLC2A12 gene. Glucose transporter ... Wood IS, Hunter L, Trayhurn P (2003). "Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in ... Joost HG, Thorens B (Jan 2002). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence ... 2006). "Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of ...
... facilitated glucose transporter member 6 is a protein that in humans is encoded by the SLC2A6 gene. Hexose transport into ... "Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular ... Doege H, Bocianski A, Joost HG, Schürmann A (September 2000). "Activity and genomic organization of human glucose transporter 9 ... "Entrez Gene: SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6". Maruyama K, Sugano S (January 1994 ...
... is a protein that in humans is encoded by the SLC2A3 gene. GLUT3 facilitates the transport of glucose across the plasma ... Simpson IA, Dwyer D, Malide D, Moley KH, Travis A, Vannucci SJ (August 2008). "The facilitative glucose transporter GLUT3: 20 ... In this hypothesis, the astrocyte, which relies on GLUT1 for glucose transport, is the primary consumer of glucose in the brain ... Vannucci SJ, Maher F, Simpson IA (September 1997). "Glucose transporter proteins in brain: delivery of glucose to neurons and ...
Henderson PJ (Mar-Apr 1990). "The homologous glucose transport proteins of prokaryotes and eukaryotes". Research in ... "Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome" (PDF). ... Protein domains, Transmembrane proteins, Articles containing video clips, Protein superfamilies, Transport proteins). ... amino acids and oxyanions were all transported by MFS family members. These proteins energetically drive transport utilizing ...
Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that ... "Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter ... "Entrez Gene: solute carrier family 2 (facilitated glucose transporter)". Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young ... Glucose transporter GRCh38: Ensembl release 89: ENSG00000197241 - Ensembl, May 2017 GRCm38: Ensembl release 89: ...
... glucose transport proteins, facilitative MeSH D12.776.543.585.500.500.500 - glucose transporter type 1 MeSH D12.776.543.585. ... glucose transporter type 5 MeSH D12.776.543.585.500.750 - sodium-glucose transport proteins MeSH D12.776.543.585.500.750.500 - ... sodium-glucose transport proteins MeSH D12.776.543.585.450.625.562.500 - sodium-glucose transporter 1 MeSH D12.776.543.585. ... organic anion transport protein 1 MeSH D12.776.543.585.450.074.750 - phosphate transport proteins MeSH D12.776.543.585.450.074. ...
... proteins are bound to the cell membrane and have the role of transporting glucose through the membrane into the cells, against ... Phloretin, the active metabolite of phlorizin, is a potent inhibitor of facilitative glucose transporters and phlorizin seems ... They play a role in renal glucose reabsorption and in intestinal glucose absorption. Blood glucose is freely filtered by the ... Drugs that inhibit sodium/glucose cotransporter 2 inhibit renal glucose reabsorption which leads to enhanced urinary glucose ...
... glucose transport proteins, facilitative MeSH D12.776.157.530.500.500.500 - glucose transporter type 1 MeSH D12.776.157.530. ... glucose transporter type 5 MeSH D12.776.157.530.500.750 - sodium-glucose transport proteins MeSH D12.776.157.530.500.750.500 - ... sodium-glucose transport proteins MeSH D12.776.157.530.450.625.437.500 - sodium-glucose transporter 1 MeSH D12.776.157.530. ... organic anion transport protein 1 MeSH D12.776.157.530.450.074.750 - phosphate transport proteins MeSH D12.776.157.530.450.074. ...
... facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose ... enhancing the capacity of glucose transport. Basolateral GLUT2 in enterocytes also aids in the transport of fructose into the ... "The mutation spectrum of the facilitative glucose transporter gene SLC2A2 (GLUT2) in patients with Fanconi-Bickel syndrome". ... Similarly, a recent study showed that lack of GLUT2 in β-cells doesn't impair glucose homeostasis or glucose-stimulated insulin ...
Proteins are also important in cell signaling, immune responses, cell adhesion, active transport across membranes, and the cell ... where it can be used for the production of glucose. Other than fat, glucose is stored in most tissues, as an energy resource ... Bell GI, Burant CF, Takeda J, Gould GW (September 1993). "Structure and function of mammalian facilitative sugar transporters ... This is done in eukaryotes by a series of proteins in the membranes of mitochondria called the electron transport chain. In ...