"Entrez Gene: C-src tyrosine kinase". Retrieved 2013-07-11. Bergman M, Mustelin T, Oetken C, Partanen J, Flint NA, Amrein KE, ... Tyrosine-protein kinase CSK also known as C-terminal Src kinase is an enzyme that, in humans, is encoded by the CSK gene. This ... CSK acts by suppressing the activity of the Src family of protein kinases by phosphorylation of Src family members at a ... "C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family ...

Src-like-adapter 2 is a protein that in humans is encoded by the SLA2 gene. This gene encodes a member of the SLAP family of ... "Entrez Gene: SLA2 Src-like-adaptor 2". Pandey A, Ibarrola N, Kratchmarova I, Fernandez MM, Constantinescu SN, Ohara O, ... "A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell ... Sawasdikosol S, Lodish HF, Mann M (May 2002). "A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 ( ...

Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene. This gene encodes a T ... "Entrez Gene: SKAP1 src kinase associated phosphoprotein 1". Wang H, Moon EY, Azouz A, Wu X, Smith A, Schneider H, Hogg N, Rudd ... Kouroku Y, Soyama A, Fujita E, Urase K, Tsukahara T, Momoi T (November 1998). "RA70 is a src kinase-associated protein ... Wu L, Fu J, Shen SH (April 2002). "SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription". ...

The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated ... "Entrez Gene: SKAP2 src kinase associated phosphoprotein 2". Alenghat FJ, Baca QJ, Rubin NT, Pao LI, Matozaki T, Lowell CA, ... Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. ... Kouroku Y, Soyama A, Fujita E, Urase K, Tsukahara T, Momoi T (November 1998). "RA70 is a src kinase-associated protein ...

... human gene location in the UCSC Genome Browser. TOM1L1 human gene details in the UCSC Genome Browser. Overview of all ... Seykora JT, Mei L, Dotto GP, Stein PL (2002). "'Srcasm: a novel Src activating and signaling molecule". J. Biol. Chem. 277 (4 ... "Entrez Gene: TOM1L1 target of myb1 (chicken)-like 1". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace ... TOM1-like protein 1 is a protein that in humans is encoded by the TOM1L1 gene. GRCh38: Ensembl release 89: ENSG00000141198 - ...

Src homology 3) SH2 - (Src homology 2) C-terminus - tyrosine kinase, catalytic domain ITK (gene) has been shown to interact ... This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein is thought to play a role in T-cell ... "Entrez Gene: ITK IL2-inducible T-cell kinase". Mueller, Cynthia; August, Avery (2003-05-15). "Attenuation of immunological ... Shim EK, Moon CS, Lee GY, Ha YJ, Chae SK, Lee JR (2004). "Association of the Src homology 2 domain-containing leukocyte ...

... is a protein that in humans is encoded by the SHF gene. GRCh38: Ensembl release 89: ... "Entrez Gene: Src homology 2 domain containing F". Retrieved 2018-05-27. v t e (Articles with short description, Short ... description matches Wikidata, Genes on human chromosome 15, All stub articles, Human chromosome 15 gene stubs). ...

Aliases of this gene include RhoGDI2, GDID4, Rho GDI 2, and others. ARHGDIB has been shown to interact with VAV1 and Src. ... "Entrez Gene: ARHGDIB Rho GDP dissociation inhibitor (GDI) beta". "Gene Cards: ARHGDIB". Groysman M, Russek CS, Katzav S ( ... Articles with short description, Short description is different from Wikidata, Genes on human chromosome 12, Genes, Human ... Adra CN, Kobayashi H, Rowley JD, Lim B (1995). "Assignment of the human GDID4 gene, a GDP/GTP-exchange regulator, to chromosome ...

The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the long arm of chromosome 11 (band 11q13). It ... Src, ErbB2 and STATs; Cyclin D1 overexpression is correlated with shorter cancer patient survival and increased metastasis. ... "Entrez Gene: CCND1 cyclin D1". He Y, Liu Z, Qiao C, Xu M, Yu J, Li G (January 2014). "Expression and significance of Wnt ... "CCND1" Gene". GeneCards. Weizmann Institute of Science. 2013. Retrieved May 6, 2015. Withers DA, Harvey RC, Faust JB, Melnyk O ...

The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity ... "Entrez Gene: AFAP1 actin filament associated protein 1". Human AFAP1 genome location and AFAP1 gene details page in the UCSC ... 1998). "Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and ... Guappone AC, Weimer T, Flynn DC (1998). "Formation of a stable src-AFAP-110 complex through either an amino-terminal or a ...

Rous sarcoma virus contains the src gene that triggers tumor formation. Later it was found that a similar gene in cells is ... These viruses have genes called accessory genes, in addition to gag, pro, pol and env genes. Accessory genes are located ... In addition, some retroviruses may carry genes called oncogenes or onc genes from another class. Retroviruses with these genes ... In example, for the gag gene; it is translated into molecules of the capsid protein, and for the pol gene; it is translated ...

This interaction is induced through phosphorylation of the MUC1 cytoplasmic tail by Src (gene). Src is activated by the EGF ... "Entrez Gene: SEA Domain of MUC1". Ligtenberg MJ, Kruijshaar L, Buijs F, van Meijer M, Litvinov SV, Hilkens J (March 1992). " ... Li Y, Kuwahara H, Ren J, Wen G, Kufe D (March 2001). "The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 ... MUC1 and p53 were found to be associated with the p53 response element of the p21 gene promoter. This results in activation of ...

It was found that the v-Src gene in RSV is required for the formation of cancer. A function for Src tyrosine kinases in normal ... v-Src is therefore an instructive example of an oncogene whereas c-Src is a proto-oncogene. The first sequence of v-Src was ... v-Src is a gene found in Rous sarcoma virus (RSV) that encodes a tyrosine kinase that causes a type of cancer in chickens. The ... The src gene was taken up by RSV and incorporated into its genome conferring it with the advantage of being able to stimulate ...

Nau MM, Lipkowitz S (2003). "Comparative genomic organization of the cbl genes". Gene. 308: 103-13. doi:10.1016/S0378-1119(03) ... 1999). "Activating SRC mutation in a subset of advanced human colon cancers". Nat. Genet. 21 (2): 187-90. doi:10.1038/5971. ... Gene. 239 (1): 145-54. doi:10.1016/S0378-1119(99)00356-X. PMID 10571044. "Entrez Gene: CBLC Cas-Br-M (murine) ecotropic ... "Molecular cloning and characterization of a novel cbl-family gene, cbl-c". Gene. NETHERLANDS. 239 (1): 145-54. doi:10.1016/ ...

"Entrez Gene: BLK B lymphoid tyrosine kinase". Oda H, Kumar S, Howley PM (August 1999). "Regulation of the Src family tyrosine ... is a non-receptor tyrosine kinase that in humans is encoded by the BLK gene. It is of the Src family of tyrosine kinases. The ... Lin YH, Shin EJ, Campbell MJ, Niederhuber JE (1995). "Transcription of the blk gene in human B lymphocytes is controlled by two ... 1993). "Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector ...

This gene encodes a protein with src homology domain 3 (SH3) patterns. Mutations in this gene cause familial juvenile ... "A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile ... v t e (Genes on human chromosome 2, All stub articles, Human chromosome 2 gene stubs). ... "Entrez Gene: NPHP1 nephronophthisis 1 (juvenile)". Donaldson JC, Dempsey PJ, Reddy S, Bouton AH, Coffey RJ, Hanks SK (Apr 2000 ...

Mutations in this gene may be associated with Hirschsprung's disease. GDNF has the ability to activate the ERK-1 and ERK-2 ... It can also activate Src-family kinases through its GFRα1 receptor. The most prominent feature of GDNF is its ability to ... The GDNF gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the ... Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small ...

Brugge subsequently identified the protein product of the cellular gene (c-Src) from which v-Src derived. These discoveries ... It was there that she and Tony Purchio discovered the protein product of the Rous Sarcoma virus v-SRC gene. ... "Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and ... "Identification of a polypeptide encoded by the avian sarcoma virus SRC gene". Proceedings of the National Academy of Sciences. ...

"Entrez Gene: Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)". Qi H, Fournier A, Grenier J (May 2003 ... Genes on human chromosome 3, Human gene pages with Wikidata item). ... SGEF (Src homology 3 domain-containing Guanine nucleotide Exchange Factor) is a 97 kDa protein involved in intracellular ... SGEF was discovered during a screen for androgen-responsive genes in human prostate cancer cells. Subsequent northern blot ...

"Entrez Gene: SHC3 SHC (Src homology 2 domain containing) transforming protein 3". Nakamura T, Komiya M, Sone K, Hirose E, Gotoh ... SHC-transforming protein 3 is a protein that in humans is encoded by the SHC3 gene. SHC3 has been shown to interact with RICS ... O'Bryan JP, Songyang Z, Cantley L, Der CJ, Pawson T (April 1996). "A mammalian adaptor protein with conserved Src homology 2 ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 9, All stub articles, ...

"Entrez Gene: SHC2 SHC (Src homology 2 domain containing) transforming protein 2". Warner, A J; Lopez-Dee J; Knight E L; ... SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene. SHC2 has been shown to interact with Kinase ... Their differential regional expression in the brain and roles in neurotrophin and Src signaling". J Biol Chem. 273 (12): 6960-7 ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 19, All stub articles, ...

This gene may play a role in the development and normal function of the ovaries. Mutations of this gene have been linked to ... Satoh S, Tominaga T (2001). "mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber ... "Entrez Gene: DIAPH2 diaphanous homolog 2 (Drosophila)". Gasman S, Kalaidzidis Y, Zerial M (Mar 2003). "RhoD regulates endosome ... v t e (Articles with short description, Short description is different from Wikidata, Genes on human chromosome X, All stub ...

The SH2B3 gene resides on chromosome 12 at the band 12q24 and contains 12 exons. This protein belongs to the Src homology 2-B ( ... SH2B3 human gene location in the UCSC Genome Browser. SH2B3 human gene details in the UCSC Genome Browser. (Articles with short ... "Entrez Gene: SH2B3 SH2B adaptor protein 3". "BioGPS - your Gene Portal System". biogps.org. Retrieved 2016-10-11. Devallière J ... SH2B adapter protein 3 is a protein that in humans is encoded by the SH2B3 gene on chromosome 12. It is ubiquitously expressed ...

60 to 80% of colon cancers express the GAST gene. Through different experimental configurations, alteration of the GAST gene or ... Src mediates the effects of hPG80 on cell growth. 2005: Ras and β-catenin/Tcf4 pathways induce synergistic activation of the ... coding gene or the β-catenin coding gene. Mutations induction into normal intestinal stem cells is sufficient to trigger ... GAST gene which encodes hPG80 is activated by the Wnt oncogenic pathway. It is a downstream target of the β-catenin/Tcf-4 ...

... including the expressed gene EMS1". Genes Chromosomes Cancer. 6 (4): 222-31. doi:10.1002/gcc.2870060406. PMID 7685625. S2CID ... Martinez-Quiles N, Ho HY, Kirschner MW, Ramesh N, Geha RS (June 2004). "Erk/Src phosphorylation of cortactin acts as a switch ... including the expressed gene EMS1". Genes Chromosomes Cancer. 6 (4): 222-31. doi:10.1002/gcc.2870060406. PMID 7685625. S2CID ... Amplification of the genes encoding cortactin-in humans, EMS1-has been found to occur in certain tumors. Overexpression of ...

... is a protein that in humans is encoded by the SHCBP1L gene. This gene encodes a Src ... This gene is located in region of chromoso0me 1 encompassing a prostate cancer susceptibility locus. [provided by RefSeq, Sep ... "Entrez Gene: SHC binding and spindle associated 1 like". Retrieved 2018-06-26. This article incorporates text from the United ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 1, Wikipedia articles ...

It has been shown in HeLa cells that TEAD2 and SRC induce gene expression. SRF (Serum response factor) and TEAD2 interact ... Laloux I, Dubois E, Dewerchin M, Jacobs E (July 1990). "TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene ... a Src/Yes-associated protein localized in the cytoplasm". Genes & Development. 15 (10): 1229-41. doi:10.1101/gad.888601. PMC ... a Src/Yes-associated protein localized in the cytoplasm". Genes & Development. 15 (10): 1229-41. doi:10.1101/gad.888601. PMC ...

The encoded protein has tyrosine kinase activity and belongs to the src family. This gene lies in close proximity to ... "Entrez Gene: YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1". Fuhrer, D K; Yang Y C (Jul 1996). "Complex formation of ... 1993). "Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor". EMBO J. 12 ( ... Proto-oncogene tyrosine-protein kinase Yes is a non-receptor tyrosine kinase that in humans is encoded by the YES1 gene. This ...

... encoding gene (HCK) confirms conservation of exon-intron structure among human PTKs of the src family". Gene. 113 (2): 275-80. ... Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene. The protein encoded by this gene is a ... HCK has been shown to interact with: ADAM15 BCR gene, Cbl gene, ELMO1, Granulocyte colony-stimulating factor receptor, RAPGEF1 ... HCK and the Src family kinases have also been implicated in driving cell survival in drug-tolerant cancer cells. In addition, ...

... interacts with all members of the SRC family of steroid receptor coactivators. In HeLa cells TEAD1 and SRC induce gene ... Laloux I, Dubois E, Dewerchin M, Jacobs E (July 1990). "TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene ... a Src/Yes-associated protein localized in the cytoplasm". Genes & Development. 15 (10): 1229-41. doi:10.1101/gad.888601. PMC ... a Src/Yes-associated protein localized in the cytoplasm". Genes & Development. 15 (10): 1229-41. doi:10.1101/gad.888601. PMC ...