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Focal-adhesion kinases (FAKs), cytoplasmic protein tyrosine kinases involved in signalling through integrins. Janus tyrosine ... Non-receptor tyrosine-protein kinase TYK2. Protein-tyrosine phosphatases PTPN3 and PTPN4, enzymes that appear to act at ... kinases (JAKs), cytoplasmic tyrosine kinases that are non-covalently associated with the cytoplasmic tails of receptors for ... Caenorhabditis elegans protein phosphatase ptp-1. Chishti AH, Kim AC, Marfatia SM, Lutchman M, Hanspal M, Jindal H, Liu SC, Low ...

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Rho family GTPases, integrin linked kinase and focal adhesion kinase (FAK) activate cyclin D gene in response to integrin. ... October 2000). "The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP- ... The MAP kinase ERK activates the downstream transcription factors Myc, AP-1 and Fos which in turn activate the transcription of ... Cyclin D is regulated by the downstream pathway of mitogen receptors via the Ras/MAP kinase and the β-catenin-Tcf/LEF pathways ...

... promotes motility of cancer cells through activation of focal adhesion kinase (FAK)". Biotechnol. Lett. 28 (24): 2057-63. doi: ... 307 (1): 52-63. doi:10.1016/s0006-291x(03)01121-5. PMID 12849980. Shim H, Lee H, Jeoung D (2006). "Cancer/testis antigen cancer ... 1091 (1): 218-24. Bibcode:2006NYASA1091..218L. doi:10.1196/annals.1378.068. PMID 17341616. S2CID 28013856. Kim Y, Jeoung D ( ...

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The SH3 domain is a point of contact with polyproline sequences on focal adhesion kinase (FAK). or the related kinase PTK2B, ... In normal untransformed cells, EFS acts as a SRC family kinase substrate in neurite outgrowth, a process that is dependent on ... Upon T-cell receptor (TCR) stimulation, EFS dephosphorylation and release of the SRC family kinase FYN and phospholipase C-γ ... However, the conserved functional properties of EFS relevant to cellular adhesion and migration, and RTK signaling, suggest ...