Vascular endothelial growth factor
Endothelial_Growth_Factor - the Vascular Endothelial Growth Factor Structure in Interactive 3D (Wikipedia articles needing page ... VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are ... "Transcriptional regulation of vascular endothelial growth factor in cancer". Cytokine Growth Factor Rev. 16 (1): 77-89. doi: ... Vascular endothelial growth factor-R3 has been detected in lymphatic endothelial cells in CL of many species, cattle, buffalo ...
Vascular endothelial growth factor C
... (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular ... January 1998). "Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and ... January 2004). "Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic ... January 2003). "Vascular endothelial growth factor-C expression in human gallbladder cancer and its relationship to lymph node ...
Vascular endothelial growth factor B
March 1996). "Vascular endothelial growth factor B, a novel growth factor for endothelial cells". Proceedings of the National ... VEGF-B is a growth factor that belongs to the vascular endothelial growth factor family, of which VEGF-A is the best-known ... Vascular endothelial growth factor B also known as VEGF-B is a protein that, in humans, is encoded by the VEGF-B gene. ... "Extracellular matrix tenascin-X in combination with vascular endothelial growth factor B enhances endothelial cell ...
Vascular endothelial growth factor A
... has been shown to interact with: ADAMTS1, CTGF, and NRP1, Vascular endothelial growth ... This gene is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes ... "Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis". FASEB ... "Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 ...
Vascular endothelial growth factor (VEGF) IRES A
Page for Vascular endothelial growth factor (VEGF) IRES A at Rfam v t e (GO template errors, Cis-regulatory RNA elements, All ... This family represents the vascular endothelial growth factor (VEGF) internal ribosome entry site (IRES) A. VEGF is an ... "Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA ... endothelial cell mitogen with many crucial functions such as embryogenic development and wound healing. The 5' UTR of VEGF mRNA ...
Endothelial stem cell
... vascular endothelial growth factors VEGF-C and VEGF-D function as ligands for the vascular endothelial growth factor receptor 3 ... "Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor". EMBO Journal. ... Inverse of endothelial dysfunction also occurs when other risk factors are treated. With a decline in EPCs the body loses its ... Piecewicz SM, Pandey A, Roy B, Xiang SH, Zetter BR, Sengupta S (2012). "Insulin-like growth factors promote vasculogenesis in ...
Decoy
For instance, the receptor VEGFR-1 can prevent vascular endothelial growth factor (VEGF) from binding to the VEGFR-2 The TNF ... Hugo H. Marti (2013). Vascular Endothelial Growth Factor. Landes Bioscience. Zalevsky J, Secher T, Ezhevsky SA, et al. (August ...
Philip Lazarovici
"Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay". Neurotrophic Factors. Methods in Molecular ... "Down-regulation of Epidermal Growth Factor Receptors by Nerve Growth Factor in PC12 Cells Is p140trk-, Ras-, and Src-dependent ... "Transcriptional Down-regulation of Epidermal Growth Factor (EGF) Receptors by Nerve Growth Factor (NGF) in PC12 Cells". Journal ... "Transcriptional Down-regulation of Epidermal Growth Factor (EGF) Receptors by Nerve Growth Factor (NGF) in PC12 Cells". Journal ...
Therapeutic angiogenesis
Vascular endothelial growth factor 1. Isner JM. Therapeutic angiogenesis: a new frontier for vascular therapy. Vasc Med. 1996 1 ... Spatiotemporal control over growth factor signaling for therapeutic neovascularization. Adv Drug Deliv Rev. 2007 Nov 10;59(13): ...
Neutron capture therapy of cancer
... epidermal growth factor receptor; MoAbs, monoclonal antibodies; VEGF, vascular endothelial growth factor. The major challenge ... factor for BPA in skin of 2.5. A relative biological effectiveness (RBE) or CBE factor of 3.2 has been used in all tissues for ... The RBE factor is used to compare the biologic effectiveness of different types of ionizing radiation. The high-LET components ... From these results, it was concluded that BNCT was effective in locally controlling tumor growth, shrinking tumors, and ...
List of Italian inventions and discoveries
"Napoleone Ferrara and the saga of vascular endothelial growth factor". Endothelium: Journal of Endothelial Cell Research. 15 (1 ... NGF or nerve growth factor, a protein involved primarily in the growth, as well as the maintenance, proliferation, and survival ... vascular endothelial growth factor' in 1989, while working at Genentech. He is credited with developing a whole new class of ... "The Multiple Life of Nerve Growth Factor: Tribute to Rita Levi-Montalcini (1909-2012)". Balkan Medical Journal. 30 (1): 4-7. ...
Radiation retinopathy
Anti-vascular endothelial growth factors have been recently used for the treatment of radiation retinopathy. Monitoring of ... Radiation however, damages the endothelial cells. The management of radiation retinopathy is similar to that for diabetic ...
Basic fibroblast growth factor
Heparin-binding growth factor-2; and Endothelial cell growth factor-2. Gene sequencing revealed that this group is the same ... Fibroblast growth factor 2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling ... Ribatti D, Vacca A, Rusnati M, Presta M (2007). "The discovery of basic fibroblast growth factor/fibroblast growth factor-2 and ... Angiogenesis Anxiety disorders Cytokine Fibroblast growth factor Growth factor Proteases in angiogenesis Receptor (biochemistry ...
Diabetic retinopathy
2020, "Anti-Vascular Endothelial Growth Factor Therapy". Kuroiwa, Malerbi & Regatieri 2021, "Laser". Flaxel et al. 2020, " ... Dervenis P, Dervenis N, Smith JM, Steel DH (May 2023). "Anti-vascular endothelial growth factors in combination with vitrectomy ... Virgili G, Parravano M, Evans JR, Gordon I, Lucenteforte E (October 2018). "Anti-vascular endothelial growth factor for ... 2021, "Risk factors, preventive factors, and biomarkers". Forrest IS, Chaudhary K, Paranjpe I, Vy HM, Marquez-Luna C, Rocheleau ...
VEGFR1
Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. FLT1 is a member of VEGF ... FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B). VEGF receptors GRCh38: Ensembl ... Shibuya M (2007). "Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis". ... Petrova TV, Makinen T, Alitalo K (November 1999). "Signaling via vascular endothelial growth factor receptors". Experimental ...
FLT4
Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI (March 1996). "Vascular endothelial growth factor-related protein: a ligand ... This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be ... Petrova TV, Makinen T, Alitalo K (November 1999). "Signaling via vascular endothelial growth factor receptors". Experimental ... "Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 ( ...
Cambiogenplasmid
"Vascular endothelial growth factor gene therapy - HSCI". Adis Insight. Springer Nature Switzerland AG. "Gene Therapy for PAD ... it delivers the gene encoding for vascular endothelial growth factor (VEGF). Neovasculogen is a plasmid encoding the CMV ...
Prostaglandin EP2 receptor
Vascular endothelial growth factor production and thereby of tumor vascularization; regulation of endothelial cell motility and ... interference with transforming growth factor-β's anti-cell proliferation activity; and, more recently, regulation of host anti- ... Scandella E, Men Y, Gillessen S, Förster R, Groettrup M (August 2002). "Prostaglandin E2 is a key factor for CCR7 surface ... PKA activates various types of signaling molecules such as the transcription factor CREB which lead to different types of ...
Neuropilin 2
"Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor ... regulation of transforming growth factor-β and platelet-derived growth factor signaling in the vasculature". Current Opinion in ... Gluzman-Poltorak Z, Cohen T, Shibuya M, Neufeld G (June 2001). "Vascular endothelial growth factor receptor-1 and neuropilin-2 ... January 2002). "Selective upregulation of vascular endothelial growth factor receptors neuropilin-1 and -2 in human ...
Glaucoma
Rittiphairoj, Thanitsara; Roberti, Gloria; Michelessi, Manuele (3 April 2023). "Anti-vascular endothelial growth factor for ... but actually it is a risk factor. Ocular hypertension (increased pressure within the eye) is the most important risk factor for ... most ophthalmologists favor treatment of those with additional risk factors. Risk factors for glaucoma include increasing age, ... Other factors can cause glaucoma, known as "secondary glaucoma", including prolonged use of steroids (steroid-induced glaucoma ...
Pachydermoperiostosis
... such as Von Willebrand factor and vascular endothelial growth factor (VEGF). These substances could also have a role in PDP ... platelet-derived growth factor (PDGF) and epidermal growth factor (EGF). It has not been described yet what role these ... 2000). "Vascular endothelial growth factor and hypertrophic osteoarthropathy". Clin Exp Rheumatol. 18 (1): 57-62. PMID 10728444 ... Von Willebrand factor is a marker of platelet and endothelial activation. This suggests that the activation of endothelial ...
Anti-VEGF
Anti-vascular endothelial growth factor therapy, also known as anti-VEGF (/vɛdʒˈɛf/) therapy or medication, is the use of ... Braithwaite T, Nanji AA, Lindsley K, Greenberg PB (May 2014). "Anti-vascular endothelial growth factor for macular oedema ... Virgili G, Parravano M, Evans JR, Gordon I, Lucenteforte E (October 2018). "Anti-vascular endothelial growth factor for ... "Anti-vascular endothelial growth factor for control of wound healing in glaucoma surgery". Cochrane Database of Systematic ...
Secondary glaucoma
While some studies recommend the use of anti-vascular endothelial growth factor drugs for inhibition of neovascularization in ... "Anti-vascular endothelial growth factor for neovascular glaucoma". Cochrane Database of Systematic Reviews. 2020 (2): CD007920 ... Risk factors for secondary glaucoma include uveitis, cataract surgery and also intraocular tumours. Common treatments are ... This results in the accumulation of aqueous and thus elevated IOP, which is a common risk factor for the progression of ...
Mitogen
Some growth factors, such as vascular endothelial growth factor, are also capable of directly acting as mitogens, causing ... Other well-known mitogenic growth factors include platelet derived growth factor (PDGF) and epidermal growth factor (EGF). ... This is not true for all growth factors, as some growth factors instead appear to cause mitogenic effects like growth ... "Vascular Endothelial Growth Factor is a Secreted Angiogenic Mitogen". 8 December 1989, Science, Vol. 246, pp 1306-1309. Morgan ...
Autocrine signaling
Another agent involved in autocrine cancer signaling is vascular endothelial growth factor (VEGF). VEGF, produced by carcinoma ... Weigand, Melanie; Hantel, Pia; Kreienberg, Rolf; Waltenberger, Johannes (2005). "Autocrine vascular endothelial growth factor ... One approach used by tumors to upregulate growth and survival is through autocrine production of growth and survival factors. ... For example, despite widespread expression of epidermal growth factor receptors (EGFRs) and EGF family ligands in non-small- ...
RNA therapeutics
Mousa SA, Mousa SS (June 2010). "Current status of vascular endothelial growth factor inhibition in age-related macular ... Ferrara N, Adamis AP (June 2016). "Ten years of anti-vascular endothelial growth factor therapy". Nature Reviews. Drug ... Examples of RNA aptamer molecular targets and potential targets include vascular endothelial growth factor, osteoblasts, and C- ... Tumor growth was significantly delayed and extended survival in mice. SLR14 improved antitumor efficacy of anti-PD1 antibody ...
Molecular processor
Vascular endothelial growth factor (VEGF) and enhanced green fluorescent protein (EGFP) cDNA was ligated to either side of an ... Leung, D.; Cachianes, G; Kuang, W.; Goeddel, D.; Ferrara, N (1989). "Vascular endothelial growth factor is a secreted ... engineered cells produce a bioluminescent marker and a chemotactic growth factor. In this instance, increased fluorescence of ... A key factor that differentiates molecular processors is "the ability to control output" of protein or peptide concentration as ...
Retinopathy
Vascular endothelial growth factor (VEGF) seems to play a vital role in promoting neovascularization. Using anti-VEGF drugs ( ... Sankar MJ, Sankar J, Chandra P (January 2018). "Anti-vascular endothelial growth factor (VEGF) drugs for treatment of ... March 2023). "Anti-vascular endothelial growth factor for proliferative diabetic retinopathy". The Cochrane Database of ... antibodies to sequester the growth factor), research have shown significant reduction in the extent of vessel outgrowth. Low ...
Kinase insert domain receptor
"Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism ... "16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells". ... Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor ... Holmes K, Roberts OL, Thomas AM, Cross MJ (October 2007). "Vascular endothelial growth factor receptor-2: structure, function, ...
Endothelial cell anergy
... vascular endothelial growth factor (VEGF) or fibroblast growth factor (FGF). The result of endothelial cell anergy in a tumor ... is the result of exposure to angiogenic growth factors. Next to endothelial cell anergy, there are more vascular mechanisms ... Endothelial cell anergy was first described in 1996 when it was shown that endothelial cells in a tumor are not able to ... Endothelial cell anergy is a condition during the process of angiogenesis, where endothelial cells, the cells that line the ...