... (MDR), multidrug resistance or multiresistance is antimicrobial resistance shown by a species of ... Drug resistance MDRGN bacteria Xenobiotic metabolism NDM1 enzymatic resistance Herbicide resistance P-glycoprotein A.-P. ... Drug+Resistance,+Multiple at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Boucher, HW, Talbot GH, ... Li XZ, Nikaido H (August 2009). "Efflux-mediated drug resistance in bacteria: an update". Drugs. 69 (12): 1555-623. doi:10.2165 ...

Laser Optofluidics in Fighting Multiple Drug Resistance. Bentham Science Publishers. p. 119. "Mechanisms of HIV-1 drug ... One of the two types of HIV drug resistance is induced resistance. Induced resistance refers to resistance that occurs as a ... The other type of HIV drug resistance is primary resistance. Primary resistance refers to resistance that is not incurred as a ... Drug resistance Larder B (2001). "Mechanisms of HIV-1 drug resistance". AIDS. 15 Suppl 5: S27-34. doi:10.1097/00002030- ...

"Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance". Cancer Research. 68 (1): 190-7. doi: ... She M, Chen X (January 2009). "Targeting Signal Pathways active in Cancer Stem Cells to Overcome Drug Resistance". Zhongguo Fei ... Multiple CSCs have been reported in prostate, lung and many other organs, including liver, pancreas, kidney or ovary. In ... It has multiple isoforms, including CD44H, which exhibits high affinity for hyaluronate and CD44V which has metastatic ...

"Dodecyltriphenylphosphonium inhibits multiple drug resistance in the yeast Saccharomyces cerevisiae". Biochemical and ... The drug "Visomitin" on the basis of SkQ1 used in veterinary practice for the treatment of ophthalmologic diseases in pets. In ... Substances of this type, various drugs that are based on them, as well as methods of their use are patented in Russia and other ... In 2016, phase 1 of a clinical trial of an oral drug containing SkQ1 was conducted in Russia. In 2017, it was found that SkQ ...

"Cytokines in cancer drug resistance: cues to new therapeutic strategies". Biochimica et Biophysica Acta (BBA) - Reviews on ... PMID 10328771.{{cite journal}}: CS1 maint: multiple names: authors list (link) de Wildt, R. M., Mundy, C. R., Gorick, B. D., ... PMID 26993403.{{cite journal}}: CS1 maint: multiple names: authors list (link) Burkholder B., Burgess R.Y. R., Luo S.H., Jones ... PMID 24440852.{{cite journal}}: CS1 maint: multiple names: authors list (link) Lin Y.; Luo S.; Shao N.; Wang S.; Duan C.; ...

Drugs and Drug Resistance. 2: 11-19. doi:10.1016/j.ijpddr.2012.01.003. PMC 3862432. PMID 24533267.{{cite journal}}: CS1 maint: ... Patients with multiple risk factors were cured, and no unexpected safety signals were detected. In June 2021, Malaysia granted ... The Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients' needs-driven, non-profit drug research and ... DNDi has built a large drug pipeline for neglected diseases with both improvements on existing drugs and entirely new chemical ...

... has attracted increased clinical attention because of its multiple drug resistance. In vitro, more than 90% of C ... It has attracted widespread attention because of its multiple drug resistance. Treatment is also complicated because it is ... which helps to explain its multiple drug resistance. Its genome also encodes virulence-related gene families such as lipases, ... and/or drug resistance. The phylogenetics of C. auris suggest distinct genotypes exist in different geographical regions with ...

Saha M, Sarkar A (December 2021). "Review on Multiple Facets of Drug Resistance: A Rising Challenge in the 21st Century". ... Resistance to recently developed drugs such as artemisinin has also been reported. The problem of drug resistance in malaria ... Resistance to HIV antivirals is problematic, and even multi-drug resistant strains have evolved. One source of resistance is ... The WHO defines antimicrobial resistance as a microorganism's resistance to an antimicrobial drug that was once able to treat ...

In some cases, cancers can evolve resistance to multiple drugs, called multiple drug resistance. There are two general causes ... Epigenetic modifications in antineoplastic drug resistance play a major role in cancer development and drug resistance as they ... or the multiple drug resistance protein, is a phosphorylated and glycosylated membrane transporter that can shuttle drugs out ... their multiple drug resistance. There are two general causes of antineoplastic therapy failure: Inherent resistance, such as ...

... a cyanobacterial indolinone that circumvents multiple drug resistance". Molecular Pharmacology. 49 (2): 288-94. PMID 8632761. ( ... Canizal G, Ascencio JA, Gardea-Torresday J, Yacamán MJ (2001). "Multiple Twinned Gold Nanorods Grown by Bio-reduction ...

1987). "Localization of the human multiple drug resistance gene, MDR1, to 7q21.1". Hum. Genet. 77 (2): 142-4. doi:10.1007/ ... 2003). "Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with ... 2003). "Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with ... Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full ...

Multiple drug resistance Methicillin-resistant Staphylococcus aureus Irving, Michael (2022-08-11). "New antibiotic molecule ... The drug inhibits the bacterial enzyme FabI, which is an important enzyme in bacterial fatty acid biosynthesis. Clinical trials ... Global deaths attributable to antimicrobial resistance (AMR) numbered 1.27 million in 2019. That year, AMR may have contributed ... Davis, Joe (2022-08-11). "Antibiotic-resistant bacteria: New drug can fight off 300 different types of superbugs". timetotimes. ...

"Promising Anti-Mitochondrial Agents for Overcoming Acquired Drug Resistance in Multiple Myeloma". Cells. 10 (2): 439. doi: ... Drugs missing an ATC code, Drugs with no legal status, Articles containing unverified chemical infoboxes, All stub articles, ... Nervous system drug stubs, Antineoplastic and immunomodulating drug stubs, Receptor antagonists). ... Resatorvid (TAK-242) is a cyclohexane derivative that was invented by scientists at Takeda in a drug discovery campaign to ...

There is no drug resistance found for the mutations described. Although the gene is typically expressed, the deletion of the ... As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through ...

Plasmodium falciparum resistance to artemisinin drugs was first confirmed in western Cambodia; treatment failures to ... Phnom Penh: NCPEMC, Ministry of Health.{{cite journal}}: CS1 maint: multiple names: authors list (link) "'We're Testing About ... Artemisinin drugs are the first-line treatment for malaria throughout the Greater Mekong Subregion. ... Challenges to reaching national elimination goals include mobile populations and artemisinin resistance. Mobile populations are ...

... antimicrobial resistance and multiple drug resistance. She investigates pathogens including MRSA, ESBL, VRE, and MDR-TB. ... and antimicrobial resistance. She is an associate professor of medical microbiology at Addis Ababa University. Woldeamanuel ...

In Memoriam". International Weigl Conference (Microorganisms in Pathogenesis and their Drug Resistance - Programme and ... Archived from the original on 15 March 2006.{{cite web}}: CS1 maint: multiple names: authors list (link) Art Golab, "Chicago's ... In an attempt to discourage Poles from helping the Jews and to destroy any efforts of the resistance, the Germans applied a ... Witold Pilecki was a member of the Polish Armia Krajowa (AK) resistance, and the only person who volunteered to be imprisoned ...

... including M184V and multiple thymidine analogue mutations (TAMs). In early studies, no mutations causing drug resistance were ... expected results from simultaneous provision of the drug alongside two other marketed drugs when compared to those drugs with ... Articles with short description, Short description matches Wikidata, Drugs not assigned an ATC code, Drugs with non-standard ... "Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 ...

December 2014). "Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma". Nature Communications. 5 ... However, reduced levels of DDX3X during drug treatment explains the development of drug resistant cells frequently detected ... While high DDX3X expressing cells are drug sensitive, more proliferative and less migratory. These phenotypes can be explained ...

"Transformation of Pseudomonas putida and Escherichia coli with plasmid-linked drug-resistance factor DNA". Proceedings of the ... By the 7th century Brahmagupta had already begun using abbreviations for unknowns, even for multiple unknowns occurring in one ... doi:10.1557/PROC-267-495.{{cite journal}}: CS1 maint: multiple names: authors list (link) Gwinnett, A. John; Gorelick, L. (1993 ... ISBN 0-226-14465-8. pp 372 Balasubramaniam, R. (2000). "On the Corrosion Resistance of the Delhi Iron Pillar" (PDF). Corrosion ...

Combining multiple chemotherapeutic drugs into one treatment helps overcome the problem of drug resistance. Furthermore, ... chemotherapy was initially met with resistance by researchers concerned about the toxicity of multiple harmful drugs being used ... Importantly, Skipper also established that the use of multiple chemotherapy drugs at once provided synergistic benefits over ... combination chemotherapy allows multiple independently-acting drugs to be administered at their maximum dose, which increases ...

Saha M, Sarkar A (December 2021). "Review on Multiple Facets of Drug Resistance: A Rising Challenge in the 21st Century". ... Dadgostar P (2019-12-20). "Antimicrobial Resistance: Implications and Costs". Infection and Drug Resistance. 12: 3903-3910. doi ... Resistance in bacteria can arise naturally by genetic mutation, or by one species acquiring resistance from another. Resistance ... Fungi evolve antifungal resistance. Viruses evolve antiviral resistance. Protozoa evolve antiprotozoal resistance, and bacteria ...

2006). "Foscarnet salvage therapy for patients with late-stage HIV disease and multiple drug resistance". Antiviral Therapy. 11 ... Multiple chemicals in Infobox drug, Multiple chemicals in an infobox that need indexing, Drugboxes which contain changes to ... "Foscarnet". Drug Information Portal. U.S. National Library of Medicine. "Foscarnet sodium". Drug Information Portal. U.S. ... "Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug ...

For drug resistant cases, depending upon the pattern of drug resistance a number of regimen are available composed of a ... Standardized treatment regimen composed of multiple anti-Tuberculosis drugs are provided through the program. Typically, drug ... these provide additional drug resistance/ susceptibility testing services for a number of Anti-TB drugs.[citation needed] ... New Cases and those which exhibit no resistance are offered a six-month, short course of the four first line drugs; Isoniazid-H ...

2009 OEN Angel Oregon finalist DesignMedix: Develops drugs to combat drug resistance in multiple diseases. GadgetTrak: Theft- ...

There are multiple preventative measures that have been shown to decrease the incidences of immune medicated adverse drug ... Darunavir/r was chosen for their first therapy with drug resistance and susceptibility in mind. After eight days of treatment, ... HIV disease-related drug reaction is an adverse drug reaction caused by drugs used for the treatment of HIV/AIDS. Drug ... Diagnosis of HIV drug caused drug induced liver injury (DILI): The most important way to figure out whether the ART drug causes ...

Antibiotic resistance to this drug has been increasing, especially in southern China. Recently the gene mcr-1, which confers ... Typical uses are for infections caused by strains of multiple drug-resistant Pseudomonas aeruginosa or carbapenemase-producing ... "Neomycin sulfate (Cortisporin): Drug Side Effects and Dosing". MedicineNet. Retrieved 11 June 2017. Tsubery, H.; Ofek, I.; ... August 2005). "Resistance to the antimicrobial peptide polymyxin requires myristoylation of Escherichia coli and Salmonella ...

Intedanib is a multiple tyrosine kinase inhibitor and is the first drug to treat idiopathic pulmonary fibrosis. Indol ... They are less likely to lead to drug resistance than selective inhibitors, which increases life expectancy. 4-quinazolinamine ... Drugs.com. Retrieved 30 September 2018. "Sutent Approval History". www.drugs.com. Drugs.com. Retrieved 30 September 2018. ( ... In vitro protein binding is 99,5% for both drugs. The drugs are mainly metabolized in the liver by oxidative metabolism of ...

Unlike multiple drug resistance, and antimicrobial resistance, antimicrobial tolerance is transient, and not inherited. ... Resistance is caused by newly acquired genetic traits (by mutation or horizontal gene transfer) that are heritable and confer ... The tolerance shown in persister cells differs from antimicrobial resistance in that the tolerance is not inherited and is ... Lopez D, Vlamakis H, Kolter R (January 2009). "Generation of multiple cell types in Bacillus subtilis". FEMS Microbiol Rev. 33 ...

In general, drug resistance can develop in four different ways: 1) the drug does not bind to the target due to target changes, ... After multiple rounds of exposure adult ruminants can overcome the adverse effects of the parasite however still it act as ... Anthelmintic drug resistance is a widespread emerging problem. Resistance has been reported to all broad spectrum anthelmintics ... Infections are usually treated with broad-spectrum anthelmintics such as benzimidazole, but resistance to these drugs has ...