Colony-stimulating factors include: CSF1 - macrophage colony-stimulating factor CSF2 - Granulocyte macrophage colony- ... was called macrophage colony-stimulating factor, for granulocytes, granulocyte colony-stimulating factor, and so on. The colony ... stimulating factors (also called GM-CSF and sargramostim) CSF3 - Granulocyte colony-stimulating factors (also called G-CSF and ... The name "colony-stimulating factors" comes from the method by which they were discovered. Hematopoietic stem cells were ...

The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine ... It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 ... "Entrez Gene: CSF1 colony stimulating factor 1 (macrophage)". Jang MH, Herber DM, Jiang X, Nandi S, Dai XM, Zeller G, Stanley ER ... Macrophage+Colony-Stimulating+Factor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Overview of all ...

... (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein ... "Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by ... Duarte RF, Franf DA (June 2002). "The synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF ... "The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors". Proceedings of the ...

... (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 ( ... Colony stimulating factor 1 receptor has been shown to interact with: Cbl gene, FYN, Grb2, Suppressor of cytokine signaling 1, ... Colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34) are both CSF1R ligands. Both ligands regulate myeloid cell ... El-Gamal MI, Al-Ameen SK, Al-Koumi DM, Hamad MG, Jalal NA, Oh CH (July 2018). "Recent Advances of Colony-Stimulating Factor-1 ...

The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein ... The granulocyte colony-stimulating factor receptor is present on precursor cells in the bone marrow, and, in response to ... "Entrez Gene: CSF3R colony stimulating factor 3 receptor (granulocyte)". Mehta, H M; Futami, M; Glaubach, T; Lee, D W; Andolina ... G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belong to a ...

... (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric ... Root RK, Dale DC (March 1999). "Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor: ... a granulocyte colony-stimulating factor (G-CSF) analog) Granulocyte-macrophage colony-stimulating factor receptor Lenzilumab ... "Granulocyte-macrophage colony-stimulating factor: not just another haematopoietic growth factor". Medical Oncology. 31 (1): 774 ...

... is a receptor for granulocyte-macrophage colony-stimulating factor, which stimulates the production of white blood cells. In ... The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), ... Lia F, Rajotte D, Clark SC, Hoang T (Nov 1996). "A dominant negative granulocyte-macrophage colony-stimulating factor receptor ... Nicola NA, Metcalf D (Aug 1985). "Binding of 125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic ...

... that I should purify a colony-stimulating factor (CSF), a substance that stimulates the proliferation of blood cells in the ... Colony-stimulating factor derivatives. 1988 US Patent # 5,989,537: Inventors: Holly RD, Lok S, Foster DC, Kaushansky K, Kuijper ... Kaushansky's lab at Stony Brook focuses on hematopoietic growth factors and the regulation of their gene expression. The lab ... Methods for stimulating granulocyte-macrophage lineage using thrombopoietin. 1999 US Patent #6,099,830: Inventors: Kaushansky K ...

Sometimes also called colony-stimulating factor, multi-CSF, mast cell growth factor, MULTI-CSF, MCGF; MGC79398, MGC79399: the ... IL-3 shares the β subunit with IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF). This β subunit sharing ... "Entrez Gene: IL3 interleukin 3 (colony-stimulating factor, multiple)". Yang YC, Ciarletta AB, Temple PA, Chung MP, Kovacic S, ... Urdal DL, Price V, Sassenfeld HM, Cosman D, Gillis S, Park LS (1989). "Molecular characterization of colony-stimulating factors ...

It can be induced by macrophage colony-stimulating factor.[citation needed] It is a component of myelopoiesis. Santangelo S, ...

... and colony stimulating factor 2. However, no functional sequence genetic polylmophisms are found within the promoter, exons, or ... granulocyte macrophage colony stimulating factor, interleukin 3, interleukin 5) that: a) cause bone marrow precursor cells, i.e ... of these genes or within the common gene enhancer for interleukin 3 or colony stimulating factor 2. This suggests that the ... The location of the causal factor can be used to classify eosinophilia into two general types: extrinsic, in which the factor ...

"Lung large cell carcinoma producing granulocyte-colony-stimulating factor". The Annals of Thoracic Surgery. 83 (1): 308-310. ... including neuroendocrine tumor-related products and granulocyte-macrophage colony stimulating factor (GM-CSF). Vimentin, an ... Expression of thyroid transcription factor-1 (TTF-1), a commonly used marker for primary lung cancers, appears to be less ... There have also been reports of rhabdoid carcinomas expressing vascular endothelial growth factor (VEGF), suggesting that ...

Undifferentiated bone marrow cells are cultured in the presence of macrophage colony-stimulating factor (M-CSF; CSF-1). M-CSF ... Hamilton, Thomas A.; Zhao, Chenyang; Pavicic, Paul G.; Datta, Shyamasree (2014-11-21). "Myeloid Colony-Stimulating Factors as ... Exogenous media containing growth factors and other serums must also be added to make the cells continually viable. Full growth ... Mature macrophages and fibroblasts, which may carry unwanted growth factors, are removed. Next, IL-3 and IL-1, two growth ...

Tumor cell lines overexpressing colony stimulating factors (e.g. G-CSF and GM-CSF) have long been used in vivo models of MDSC ... Tumor cell lines overexpress colony-stimulating factors (G-CSF and GM-CSF) and IL6, which promote development of MDSCs that ... Another important factor influencing the activity of MDSC is oppressive ROS. MDSCs can also play a positive regulatory role. It ... The size of the myeloid suppressor compartment is considered to be an important factor in the success or failure of cancer ...

This type is refractory to granulocyte colony-stimulating factor. There is an absence of lysosomes in fibroblasts and depletion ... Most cases of SCN respond to treatment with granulocyte colony-stimulating factor (filgrastim), which increases the neutrophil ... Over 90% of SCN responds to treatment with granulocyte colony-stimulating factor (filgrastim), which has significantly improved ... Neutrophil survival is normal.[citation needed] Regular administration of exogenous granulocyte colony-stimulating factor ( ...

Granulocyte colony-stimulating factor (G-CSF), available as filgrastim, can reduce the risk of infection. In some cases, G-CSF ... "Granulocyte colony-stimulating factor in glycogen storage disease type 1b. Results of the European Study on Glycogen Storage ... "Thrombocytopenia in association with splenomegaly during granulocyte-colony-stimulating factor treatment in mice is not caused ... "Different effects of granulocyte colony-stimulating factor and erythropoietin on erythropoiesis". Stem Cell Research & Therapy ...

It is a colony-stimulating factor that stimulates megakaryocyte production. It functions by stimulating ligands for interleukin ... a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling ... cells with stem cell factor and promegapoietin". Exp Hematol. 28 (3): 335-46. doi:10.1016/S0301-472X(99)00152-6. PMID 10720698 ...

Cannarile MA, Weisser M, Jacob W, Jegg AM, Ries CH, Rüttinger D (July 2017). "Colony-stimulating factor 1 receptor (CSF1R) ... TAMs secrete the pro-angiogenic factors tumor necrosis factor α (TNFα), basic fibroblast growth factor, urokinase-type ... The most highly expressed and well-characterized angiogenic factor produced by TAMs is vascular endothelial growth factor A ( ... When angiopoietin-2 is bound, these TAMs upregulate expression of more angiogenic factors, such as thymidine phosphorylase and ...

"Circadian variation of granulocyte colony stimulating factor levels in man". British Journal of Haematology. 106 (2): 368-70. ... of circulating white blood cells and changes in the levels of hematopoietic cytokines and granulocyte colony stimulating factor ... GCSF). Antipsychotics may amplify the natural variation in these hematopoietic factors.[citation needed] Neutropenia is a ...

During this time, the group led by Professor Donald Metcalf discovered and characterised the colony-stimulating factors (CSFs ... Later, Professor Donald Metcalf discovered and characterised colony-stimulating factors. As of 2015[update], the institute ...

In this context, the colony-stimulating factor 1 (CSF1)/colony-stimulating factor 1 receptor (CSF1R) axis has gained the most ... TGCT tumors grow due to genetic overexpression of colony stimulating factor 1. This causes colony-stimulating factor-1 receptor ... "Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy". Journal for Immunotherapy of Cancer. 5 (1): 53. doi ...

... (tradename Leukine) is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as ... "Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor". Blood. 92 (12): 4491-508. doi: ...

One notable example is the granulocyte macrophage colony-stimulating factor. The goal of this stimulated immune response is ... The goal is to stimulate the person's immune system in order to prevent future infections that may result in an acute episode ... For example, female sex hormones are known to stimulate both adaptive and innate immune responses. Some autoimmune diseases ... Dorshkind, Kenneth; Horseman, Nelson D. (1 June 2000). "The Roles of Prolactin, Growth Hormone, Insulin-Like Growth Factor-I, ...

Research regarding the production of granulocyte colony stimulating factor (G-CSF) is being conducted to investigate AMML ... "Production of granulocyte colony-stimulating factor by acute myelomonocytic leukemia cells". Leukemia Research. 12 (9): 745-750 ... Acquired predisposing factors include: aplastic anemia, chemotherapy, prenatal exposure to tobacco, marihuana, and alcohol. ... "Acute Myeloid Leukemia (AML) Subtypes and Prognostic Factors". www.cancer.org. Retrieved 2019-12-14. Shirafuji, Naoki; Asano, ...

Minnerup J, Sevimli S, Schäbitz WR (October 2009). "Granulocyte-colony stimulating factor for stroke treatment: mechanisms of ... March 2003). "Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia". Stroke. 34 (3): ... "Granulocyte-Colony Stimulating Factor (G-CSF) for stroke: an individual patient data meta-analysis". Scientific Reports. 6: ... "Clinical Development Success Rates and Contributing Factors 2011-2020" (PDF). Retrieved 11 May 2022. Munich SA, Vakharia K, ...

Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF). There is some controversy over which ... ISBN 0-8385-8285-0. CFU-GM at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Colony forming units ... CFU-GM, also known as granulocyte-macrophage progenitor (GMP), is a colony forming unit. It is derived from CFU-GEMM. The "GM" ... Nomenclature of hematopoietic colonies and lineages "Hem I WBC Morphology and Physiology". Archived from the original on ...

An eosinophil-specific colony-stimulating factor with activity for human cells". J. Exp. Med. 163 (5): 1085-1099. doi:10.1084/ ... and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in Th2 cells. IL-5 is also ... and granulocyte-macrophage colony-stimulating factor (GM-CSF). Glycosylation of the Asn196 residue of the Rα subunit appears to ... IL-5 was originally discovered as an eosinophil colony-stimulating factor, is a major regulator of eosinophil accumulation in ...

There is limited evidence that granulocyte colony-stimulating factor may not hasten the resolution of diabetic foot ulcer ... Cochrane Wounds Group) (August 2013). "Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot ... Growth factors - there is some low-quality evidence that growth factors may increase the likelihood that diabetic foot ulcers ... Binding of growth factors is clearly an important role of perlecan in wound healing and angiogenesis. Poor wound healing in ...

El Ouakfaoui S, Heitz D, Paquin R, Beaulieu AD (February 1999). "Granulocyte-macrophage colony-stimulating factor modulates ...

Lin, E. Y.; Nguyen, A. V.; Russell, R. G.; Pollard, J. W. (2001). "Colony-stimulating factor 1 promotes progression of mammary ... Chemoattractive paracrine loop of colony-stimulating factor-1 (CSF-1) and EGF ligands between tumor-associated macrophages ( ... Vascular endothelial growth factor A (VEGF-A). The role of autocrine transforming growth factor beta 1(TGF-β1) signaling on ... The RMF/EG fibroblast must then be irradiated to allow the expression of key proteins and growth factors. After 4 weeks of ...