After the first chromosome segregation in meiosis I is complete, there is further chromosome segregation during the second ... Both proper initial segregation of chromosomes in prophase I and the next chromosome segregation during equational division in ... Chromosome segregation also occurs in prokaryotes. However, in contrast to eukaryotic chromosome segregation, replication and ... Instead segregation occurs progressively following replication. During mitosis chromosome segregation occurs routinely as a ...
... is a deviation from the usual distribution of chromosomes during meiosis, that is, during ... The mitotic asymmetry with non-random segregation of chromosomes arises from unequal partitioning of chromosomes according to ... In such cases, one does not speak of X and Y chromosomes, but of Z and W chromosomes. Males have two Z chromosomes (ZZ), ... There are two different X chromosomes and no Y chromosome (X1X20), and in meiosis I both X chromosomes are assigned to the same ...
... and initiates chromosome dimer segregation. The dif site is found at the intersection between the monomers of the chromosome ... Yu XC, Weihe EK, Margolin W (December 1998). "Role of the C terminus of FtsK in Escherichia coli chromosome segregation". ... FtsK functions to coordinate cell division and chromosome segregation through its N-terminal and C-terminal domains. The FtsKN ... Bigot S, Sivanathan V, Possoz C, Barre FX, Cornet F (June 2007). "FtsK, a literate chromosome segregation machine". Molecular ...
In late anaphase, chromosomes also reach their overall maximal condensation level, to help chromosome segregation and the re- ... Santaguida S, Amon A (August 2015). "Short- and long-term effects of chromosome mis-segregation and aneuploidy". Nature Reviews ... In this stage, chromosomes are long, thin, and thread-like. Each chromosome has two chromatids. The two chromatids are joined ... Blow JJ, Tanaka TU (November 2005). "The chromosome cycle: coordinating replication and segregation. Second in the cycles ...
Specifically, Draviam monitors chromosome microtubule attachment, end-on conversion, chromosome mis-segregation and how cells ... Dravian, Viji Mythily; Sorger, Peter (2004). "Chromosome segregation and genomic stability". Current Opinion in Genetics & ... progression The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells Chromosome segregation ... Aneuploidy describes the situation where a cell contains an abnormal number of chromosomes, and often occurs in aggressive ...
Badrinarayanan, Anjana; Le, Tung B. K.; Laub, Michael T. (2015-11-13). "Bacterial Chromosome Organization and Segregation". ... No NTPase This system is also used by most bacteria for chromosome segregation. Type I partition systems are composed of an ... The StbA-stbDRs complex may be used to pair plasmid the host chromosome, using indirectly the bacterial partitioning system. ... Guynet C, de la Cruz F (2011). "Plasmid segregation without partition". Mobile Genetic Elements. 1 (3): 236-241. doi:10.4161/ ...
This point in the cell will block the segregation of chromosomes until all of the chromosomes are properly connected. It also ... Mechanisms of mitotic chromosome segregation. [Place of publication not identified]: MDPI AG. 2017. ISBN 978-3-03842-402-4. ... In 2017, McIntosh is the guest editor of Mechanisms of Mitotic Chromosome Segregation. In this work, McIntosh connects various ... Here, the researchers applied these findings to chromosome segregation and concluded that the microtubule dynamics create the ...
"Deregulation of Chromosome Segregation and Cancer". Annual Review of Cancer Biology. 4: 257-278. doi:10.1146/annurev-cancerbio- ... It is required for two microtubule-dependent processes: nuclear movement prior to anaphase, and chromosome separation. CDC20, ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 1). ...
Losada A (June 2014). "Cohesin in cancer: chromosome segregation and beyond". Nature Reviews. Cancer. 14 (6): 389-393. doi: ... February 2016). "Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in ... This is thought to be because this gene is located in the X chromosome, therefore only one mutation is needed to inactivate it ... This allows for the replicated chromosomes to separate into two new cells. Another role of STAG2 is to encode the stromal ...
"Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes". Science. 348 (6239): ... Mogessie, Binyam; Schuh, Melina (2017). "Actin protects mammalian eggs against chromosome segregation errors". Science. 357 ( ... in which oocytes mature into eggs by extruding half of their chromosomes in a small cell termed the polar body. This requires ... increasing the likelihood of segregation errors. She has also investigated the reasons why older mothers have a higher rate of ...
Jallepalli PV, Lengauer C (2001). "Chromosome segregation and cancer: cutting through the mystery". Nature Reviews Cancer. 1 (2 ... As previously stated, the disruptions in the chromosome may lead to single chromosome mutations, including deletion, ... a process that ensures that replicated chromosomes are intact before chromosomes are segregated during cell division. In ... This occurs because loss of these genes causes an increase in chromosome fusions, either in an end-to-end manner or through ...
Mary C. Dasso is an American biochemist known for research on chromosome segregation and the discovery of Ran GTPase. She is ... They are now using these systems to examine not only the role of nucleoporins in mitotic chromosome segregation but also how ... Dasso is interested in mechanisms of chromosome segregation. Her group discovered that the Ran GTPase. They showed that Ran ... re-purposed as cells divide to perform transport-independent activities that are essential for accurate chromosome segregation ...
Murray, H; Ferreira, H; Errington, J (Sep 2006). "The bacterial chromosome segregation protein Spo0J spreads along DNA from ... The parABS system is a broadly conserved molecular mechanism for plasmid partitioning and chromosome segregation in bacteria. ... "A spindle-like apparatus guides bacterial chromosome segregation". Nature Cell Biology. 12 (8): 791-8. doi:10.1038/ncb2083. PMC ... Surtees, JA; Funnell, BE (2003). Plasmid and chromosome traffic control: how ParA and ParB drive partition. pp. 145-80. doi: ...
He generated the first chromosome-wide high resolution maps of proteins involved in chromosome packaging and segregation. He ... "Frank Uhlmann: Mechanism and control of chromosome segregation". The Crick Institute. Archived from the original on 24 May 2015 ... Nasmyth, K; Peters, J. M.; Uhlmann, F (2000). "Splitting the chromosome: Cutting the ties that bind sister chromatids". Science ... "A simple biophysical model emulates budding yeast chromosome condensation". eLife. 4: e05565. doi:10.7554/eLife.05565. PMC ...
... chromosome segregation as well as development and pluripotency. Aberrations in chromatin remodeling proteins are found to be ... DNA repair and chromosome segregation, and therefore exerts tumor-suppressor function. Mutations in such chromatin remodelers ... including chromosome assembly and segregation, DNA replication and repair, embryonic development and pluripotency, and cell- ... Loss of heterozygosity in coding region of p300 (chromosome 22q13) is present in large number of glioblastomas. Further, HATs ...
Chromosome segregation Clastogen Non-disjunction Plante, N. (2003). Molecular toxicology. Taylor & Francis. pp. 63-65. ISBN 978 ... Exposure to fenvalerate raised sex chromosome disomy 1.9-fold and disomy of chromosome 18 by 2.6-fold (Xia et al., 2004). ... and also increased sex chromosome disomy by 1.7-fold and chromosome 18 disomy by 2.2-fold. Humans are exposed to perfluorinated ... An aneugen is a substance that causes a daughter cell to have an abnormal number of chromosomes or aneuploidy. A substance's ...
Chromosome segregation Candida albicans India portal Biology portal Medicine portal "Faculty - JNCASR". www.jncasr.ac.in. 3 ... Essential Components for Chromosome Segregation. Wiley-VCH Verlag GmbH & Co. KGaA. pp. 259-288. doi:10.1002/9783527697274.ch9. ... Sreekumar, Lakshmi; Varshney, Neha; Sanyal, Kaustuv (2017). Chromosome Components Important for Genome Stability in Candida ... "The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centromere protein essential for chromosome ...
Prasanth SG, Prasanth KV, Stillman B (2002). "Orc6 involved in DNA replication, chromosome segregation, and cytokinesis". ... Genes on human chromosome 16, Protein pages needing a picture, All stub articles, Human chromosome 16 gene stubs). ... interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation ...
"Human chromokinesin KIF4A functions in chromosome condensation and segregation". The Journal of Cell Biology. 166 (5): 613-620 ... "KIF4A Foundation". v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome X, All ... to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization". Cytogenetics and Cell Genetics. 88 (1-2): 41-42. doi: ... "Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during ...
Dworkin J, Losick R (October 2002). "Does RNA polymerase help drive chromosome segregation in bacteria?". Proceedings of the ... SMC proteins responsible for chromosome condensation in eukaryotic cells. Viral DNA packaging motors inject viral genomic DNA ... Peterson CL (November 1994). "The SMC family: novel motor proteins for chromosome condensation?". Cell. 79 (3): 389-92. doi: ...
Seidman, MM; Levine, AJ; Weintraub, H (1979). "The asymmetric segregation of parental nucleosomes during chromosome replication ... Riley, D; Weintraub, H (1979). "Conservative segregation of parental histones during replication in the presence of ...
Klebig C, Korinth D, Meraldi P (Jun 2009). "Bub1 regulates chromosome segregation in a kinetochore-independent manner". The ... "PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation". Developmental Cell. 10 (5): 575-85. ... The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome ... The protein kinase Bub1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome ...
It is involved in chromosome segregation during cell division. It also has a role in the orientation of microtubules to form ... It remains part of the kinetochore through early anaphase (the chromosome-dividing phase). In late anaphase, CENPF localises to ... 2005). "FoxM1 is required for execution of the mitotic programme and chromosome stability". Nat. Cell Biol. 7 (2): 126-36. doi: ... Kobayashi M, Hanai R (2001). "M phase-specific association of human topoisomerase IIIbeta with chromosomes". Biochem. Biophys. ...
... causes chromosome condensation and segregation during cell mitosis. H3S10p temporarily increases during mitosis while ...
"PKM2 regulates chromosome segregation and mitosis progression of tumor cells". Molecular Cell. 53 (1): 75-87. doi:10.1016/j. ... the spindle assembly protein Bub3 to regulate chromosome segregation and mitotic checkpoint in metaphase, and myosin light ...
... the segregation of chromosomes continue and both the phases of meiotic segregations take place on prolonged meiosis I spindle. ... Higuchi, T; Uhlmann, F (2005). "Stabilization of microtubule dynamics at anaphase onset promotes chromosome segregation". ... "The Cdc14 phosphatase and the FEAR network control meiotic spindle disassembly and chromosome segregation". Developmental Cell ... The chromosomes also segregate abnormally. The abnormality arises due to delay in dissembling of spindle during Anaphase I. ...
Then the metaphase spindle assembles and chromosome segregation can occur. The transcription of Sic1 starts during telophase, ...
Potapova T, Gorbsky GJ (February 2017). "The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis". Biology. 6 ... The spindle checkpoint (also referred to as the mitotic checkpoint) ensures proper separation of chromosomes. Broadly, the ... increasing the likelihood that each daughter cell receives only one duplicated chromosome. Such a mechanism is crucial, as ... resulting in the condensation of chromosomes. This compaction of the DNA downregulates CDKN1A transcription. USP17 ...
This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be ... "Mitotic Centromere-associated Kinesin Is Important for Anaphase Chromosome Segregation". J. Cell Biol. 142 (3): 787-801. doi: ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 1, All stub articles, ... proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes ...
"Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation". Nature Cell Biology. 4 (4): ...