Dysfunction of cell adhesion occurs during cancer metastasis. Loss of cell-cell adhesion in metastatic tumour cells allows them ... Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell ... Cells adhesion occurs from the interactions between cell-adhesion molecules (CAMs), transmembrane proteins located on the cell ... allowing vertebrate cells to assemble into organised tissues. Cadherins are essential for cell-cell adhesion and cell ...

... s (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells ... Cell membrane Cell migration Immunological synapse Trogocytosis Cell+Adhesion+Molecules at the U.S. National Library of ... Schnapp, L (2006). Integrin, Adhesion/cell-matrix. Seattle: Elsevier. García AJ (December 2005). "Get a grip: integrins in cell ... Gumbiner, B. M. (1996-02-09). "Cell adhesion: the molecular basis of tissue architecture and morphogenesis". Cell. 84 (3): 345- ...

... (formerly Cell Adhesion & Communication) is an academic journal that publishes review articles on ... Cell Communication & Adhesion homepage of Cell Communication & Adhesion (Articles with short description, Short description is ... FRACP are the regional editors of Cell Communication & Adhesion. Cell Communication & Adhesion publishes six issues per year in ... Intercellular communication Intercellular junctions Receptor-based cell recognition & signaling Cell Communication & Adhesion ...

... (sCAMs) are a class of cell adhesion molecule (CAMs - cell surface binding proteins) that may ... May 1998). "Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion". ... Soluble forms of intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin (termed sICAM-1, sVCAM-1 ... They include soluble isoforms of the cell adhesion molecules ICAM-1, VCAM-1, E-selectin and P-selectin (distinguished as sICAM- ...

2002). "The tumor suppressor protein TSLC1 is involved in cell-cell adhesion". J. Biol. Chem. 277 (34): 31014-9. doi:10.1074/ ... 2003). "Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein ... Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. Model organisms have been used in the ... Cell adhesion molecule 1 has been shown to interact with EPB41L3. Genome-wide association studies identified an association ...

1996). "A unique gene encodes spliceoforms of the B-cell adhesion molecule cell surface glycoprotein of epithelial cancer and ... 2006). "Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells". Am. J. Physiol., Cell ... This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two ... Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membrane glycoprotein that in humans is encoded by ...

"Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins". The Journal of Cell ... a human epithelial antigen is a homophilic cell-cell adhesion molecule". The Journal of Cell Biology. 125 (2): 437-46. doi: ... EpCAM was first found to play a role in homotypic cell adhesion. This means that EpCAM on the surface of one cell binds to the ... September 2018). "EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion". Scientific Reports. 8 (1): ...

... also present on subset of CD4+ T cells and CD8+ T cells. In cell adhesion, CD56 contributes to cell-cell adhesion or cell- ... Τ cells and activated CD8+ T cells, as well as on dendritic cells. NCAM has been implicated as having a role in cell-cell ... The neural cell adhesion molecule NCAM1 appears on early embryonic cells and is important in the formation of cell collectives ... Normal cells that stain positively for CD56 include NK cells, activated T cells, the brain and cerebellum, and neuroendocrine ...

... is a protein in humans that is encoded by the DSCAML1 gene. DSCAM, Down syndrome ... "DSCAML1 DS cell adhesion molecule like 1 [ Homo sapiens (human) ]". Retrieved 2012-11-29. PDBe-KB provides an overview of all ... the structure information available in the PDB for Human Down syndrome cell adhesion molecule-like protein 1 v t e (Articles ... cell adhesion molecule Fibronectin type III domain Immunoglobulin superfamily GRCh38: Ensembl release 89: ENSG00000177103 - ...

Cell-cell adhesions provide chemical and mechanical connections between adjacent cells. Of special importance to neuronal ... Cell migration is generally classified with four cell processes: Leading edge protrusion Adhesion formation Cell body ... Force transmission can occur through a variety of mechanisms, though adhesion complexes between cell-cell and cell- ... Kawauchi, T (2012). "Cell Adhesion and Its Endocytic Regulation in Cell Migration during Neural Development and Cancer ...

Cell adhesion molecules Fibronectin Laminin Schwab, Manfred, ed. (2001). "Cell Adhesion Molecules". Encyclopedic reference of ... are proteins that attach cells to specific compounds in the extracellular matrix (a process known as cell adhesion). Some of ... ISBN 978-0-387-25615-3. Ulrich, Klaus (1994). "Cell-Adhesion Molecules of Vertebrates". Comparative animal biochemistry. ... SAMs do not have to be made by the cells that bind to them. They can also link to other SAMs, influencing each other's behavior ...

Cell sorting Cell adhesion Morphogenesis Wound healing Metastasis Foty, Ramsey A.; Steinberg, Malcolm S. (1 February 2005). " ... where tissues with weaker surface adhesion surround tissues with stronger surface adhesion, the rounding of irregular cell ... cells move to be near other cells of similar adhesive strength in order to maximize the bonding strength between cells and ... As cells with similar strengths of surface adhesion bond to one another, bonding energy in the overall system increases, and ...

Leukocyte adhesion deficiency Etzioni A, Harlan JM. Cell adhesion and leukocyte adhesion defects. In: Ochs HD, Smith CIE, Puck ... This gene encodes CD18, a protein present in several cell surface receptor complexes found on white blood cells, including ... It also impairs immune cell interaction, immune recognition, and cell-killing lymphocyte functions. The lack of CR3 interferes ... Leukocyte adhesion deficiency-1 (LAD1) is a rare and often fatal genetic disorder in humans. The main sign of the disease is ...

Ligand profiles and in vitro studies have indicated a role for adhesion GPCRs in cell adhesion and migration. Work utilizing ... Articles with short description, Short description matches Wikidata, Adhesion G protein-coupled receptors, Cell adhesion ... adhesion GPCRs) are a class of 33 human protein receptors with a broad distribution in embryonic and larval cells, cells of the ... and the belief that they interact with cell to cell and cell to extra cellular matrix. While ligands for many receptors are ...

"Allogeneic hematopoietic stem cell transplantation for Leukocyte Adhesion Deficiency". Pediatrics. 123 (3): 836-840. doi: ... Leukocyte adhesion cascade Congenital disorder of glycosylation "Leukocyte Adhesion Deficiency: Immunodeficiency Disorders: ... 95 glycoproteins cause leukocyte adhesion deficiency". Cell. 50 (2): 193-202. doi:10.1016/0092-8674(87)90215-7. PMID 3594570. ... Types of leukocyte adhesion deficiency include LAD1, LAD2, and LAD3. LAD1 is the most common. Patients with LAD1 have an ...

The interthalamic adhesion contains nerve cells and nerve fibers; a few of the latter may cross the middle line, but most of ... The interthalamic adhesion (also known as the intermediate mass or middle commissure) is a flattened band of tissue that ... The interthalamic adhesion is notably enlarged in patients with the type II Arnold-Chiari malformation. Thalamus Medial surface ... It is still uncertain whether the interthalamic adhesion contains fibers that cross the midline - and for this reason, it is ...

This domain is found in mucosal vascular addressin cell adhesion molecule 1 proteins (MAdCAM-1). These are cell adhesion ... Bacterial adhesin Cell adhesion Fungal adhesin Tan K, Casasnovas JM, Liu JH, Briskin MJ, Springer TA, Wang JH (June 1998). "The ...

F9 embryonal carcinoma cells are similar to the P19 cells shown in Figure 1 and normally have cell-to-cell adhesion mediated by ... providing the cell with a means of stable cell adhesion. However, decreases in this adhesion ability of the cell has been ... A tumor cell line with defective δ-catenin, low levels of E-cadherin and poor cell-to-cell adhesion could be restored to normal ... "Knockdown of Sec6 improves cell-cell adhesion by increasing α-E-catenin in oral cancer cells". FEBS Lett. 586 (6): 924-33. doi: ...

The mechanism behind catch bonds helps to explain the biophysics behind cell-cell adhesion. According to the researchers, " ... "Bacterial adhesion to target cells enhanced by shear force". Cell. 109 (7): 913-23. doi:10.1016/S0092-8674(02)00796-1. PMID ... "Models for the specific adhesion of cells to cells". Science. 200 (4342): 618-27. Bibcode:1978Sci...200..618B. doi:10.1126/ ... Marshall BT, Long M, Piper JW, Yago T, McEver RP, Zhu C (May 2003). "Direct observation of catch bonds involving cell-adhesion ...

Fibronectins are involved in a number of important functions e.g., wound healing; cell adhesion; blood coagulation; cell ... "The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing". Nature. 375 ( ... K441 and R443 together make up a membrane-binding motif that allows EphA2 receptors to attach to the cell membrane. BSPH1; ... Pankov R, Yamada KM (2002). "Fibronectin at a glance". J Cell Sci. 115 (20): 3861-3863. doi:10.1242/jcs.00059. PMID 12244123. ...

"The roles of cell adhesion molecules in tumor suppression and cell migration: a new paradox". Cell Adhesion & Migration. 3 (4 ... "The immunoglobulin-like cell adhesion molecule hepaCAM modulates cell adhesion and motility through direct interaction with the ... April 2008). "GlialCAM, an immunoglobulin-like cell adhesion molecule is expressed in glial cells of the central nervous system ... modulating cell-matrix adhesion and migration, and b) inhibiting cancer cell growth. (Note: *HEPACAM, gene name; **hepaCAM, ...

Cell Communication & Adhesion. 10 (1): 27-36. doi:10.1080/15419060302063. PMID 12881038. S2CID 225894. Wang WH, Yang JJ, Lin YC ... However, Cx29, which is highly expressed in myelin-forming glial cells of the CNS and PNS, has not been documented to form gap ... "Identification of novel variants in the Cx29 gene of nonsyndromic hearing loss patients using buccal cells and restriction ... "Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems". The Journal ...

Cell Adhesion & Migration. 1 (4): 185-95. doi:10.4161/cam.1.4.5448. PMC 2634105. PMID 19262140. Zhu Y, Cuevas IC, Gabriel RA, ... "HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair". Journal of Cell ... HoxA3 induces endothelial cell (EC) migration by upregulating MMP14 and uPAR. Conversely, HoxD10 and HoxA5 have the opposite ... Dunn J, Simmons R, Thabet S, Jo H (October 2015). "The role of epigenetics in the endothelial cell shear stress response and ...

The protein ELKS binds to the cell adhesion protein, β-neurexin, and other proteins within the complex such as Piccolo and ... β-neurexin then binds to cell adhesion molecule, neuroligin located on the postsynaptic membrane. Neuroligin then interacts ... Paired pulse facilitation Postsynaptic density Missler M, Südhof TC, Biederer T (2012). "Synaptic cell adhesion". Cold Spring ... The ribbon synapse is a special type of synapse found in sensory neurons such as photoreceptor cells, retinal bipolar cells, ...

"Regulation of cell adhesion by protein-tyrosine phosphatases: II. Cell-cell adhesion". J Biol Chem. 281 (24): 16189-92. doi: ... The structure of PTPmu suggests that it can regulate cell adhesion and migration using its extracellular cell adhesion molecule ... Burridge K, Sastry SK, Sallee JL (2006). "Regulation of cell adhesion by protein-tyrosine phosphatases. I. Cell-matrix adhesion ... and therefore keeps cells stationary. Cadherins regulate cell-cell adhesion during development of the body and in adult tissue ...

... form focal adhesions with the substratum, linking them to the cell surface. Many types of migrating cells display ... Viruses have been shown to be transported along filopodia toward the cell body, leading to cell infection. Directed transport ... August 2020). "The Global Phosphorylation Landscape of SARS-CoV-2 Infection". Cell. 182 (3): 685-712.e19. doi:10.1016/j.cell. ... Filopodia have roles in sensing, migration, neurite outgrowth, and cell-cell interaction.[further explanation needed] To close ...

Cell Communication & Adhesion. 10 (4-6): 451-6. doi:10.1080/cac.10.4-6.451.456. hdl:10533/174413. PMID 14681056. S2CID 33491307 ... In non-excitable cells, the resting potential across the plasma membrane (Vmem) of individual cells propagate across distances ... Civitelli, R (2008). "Cell-cell communication in the osteoblast/osteocyte lineage". Archives of Biochemistry and Biophysics. ... Robinson, K. R (1985). "The responses of cells to electrical fields: A review". The Journal of Cell Biology. 101 (6): 2023-7. ...

Kos J, Jevnikar Z, Obermajer N (April-June 2009). "The role of cathepsin X in cell signaling". Cell Adhesion & Migration. 3 (2 ... It is also shown to bind cell surface heparin sulphate proteoglycans, indicating possible functions in cellular adhesion and ... This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be ... Obermajer N, Svajger U, Bogyo M, Jeras M, Kos J (November 2008). "Maturation of dendritic cells depends on proteolytic cleavage ...

Cell Communication & Adhesion. 16 (1-3): 15-27. doi:10.1080/15419060903009329. PMID 19533476. S2CID 19077857. Kirchner F, ... Plakophilin-2 over time has shown to be more than components of cell-cell junctions; rather the plakophilins are emerging as ... which was coordinate with decreased electrical coupling of cells and decreased adhesion strength. These studies were further ... Cell. Proteomics. 4 (6): 785-95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. Kimura K, Wakamatsu A, Suzuki Y, Ota T, ...

Cell Adhesion & Migration. 3 (4): 402-411. doi:10.4161/cam.3.4.8690. ISSN 1933-6926. PMC 2802756. PMID 19421003. "Newcomb ... but after this metamorphosis-induced cell death, the surviving nest cells can then differentiate. These cells become functional ... vast cell death sweeps through nests of larvae that are at the end of larval life. These nest cells were previously in an ... Venken, Koen J.T.; Simpson, Julie H.; Bellen, Hugo J. (October 2011). "Genetic Manipulation of Genes and Cells in the Nervous ...

Focal adhesions form and dissipate as cells attach and detach from matrix during cell adhesion and cell migration. The FAK ... In structural and cell biology, the focal adhesion targeting domain is a conserved protein domain that was first identified in ... are also found in other proteins that localize to paxillin-containing focal adhesions and are involved in cell adhesion and ... Hayashi I, Vuori K, Liddington RC (February 2002). "The focal adhesion targeting (FAT) region of focal adhesion kinase is a ...