Benzazepines are heterocyclic chemical compounds consisting of a benzene ring fused to an azepine ring. Examples include: ...

... is a drug originally researched as a potential opioid analgesic, but was found ... 5-methano-1H-3-benzazepine, it seems unlikely that this is actually the compound being sold. Corey lactone 4-phenylbenzoate ... 5-methano-1H-3-benzazepines". Journal of Medicinal Chemistry. 22 (4): 455-7. doi:10.1021/jm00190a020. PMID 430484. Singer, R. A ... 5-methano-1H-3-benzazepine via Oxidative Cleavage and Reductive Amination Strategies". Synthesis. 2004 (11): 1755. doi:10.1055/ ...

Adamantanes: Amantadine • Memantine • Rimantadine Aminotetralins: 7-OH-DPAT • 8-OH-PBZI • Rotigotine • UH-232 Benzazepines: 6- ...

... is a benzazepine. The chemical name for Laniquidar is methyl 11-(1-(4-quinolin-2-ylmethoxy)phenethyl)piperidin- ...

Azepane Benzazepines Diazepine Oxepin Borepin Smith, Jason A.; Molesworth, Peter P.; Hyland, Christopher J. T.; Ryan, John H. ( ...

Benzazepine Dibenzothiazepine Dibenzothiepin Dibenzoxepin Yagiela, John; Dowd, Frank; Johnson, Bart; Mariotti, Angelo; Neidle, ...

Chemically, ecopipam is a synthetic benzazepine derivative. It can be synthesized from a simple tetralin derivative: "Ecopipam ... 5-tetrahydro-1H-3-benzazepines, Chloroarenes, Dopamine antagonists, Phenols). ...

For azepine, benzazepine is the preferred name. Likewise, the compounds with two benzene rings fused to the central heterocycle ...

Azepine Benzazepines Diazepine Oxepin Borepin CR gas (dibenzoxazepine) Katritzky, A. R.; Ramsden, C. A.; Scriven, E. F. V.; ...

Some of the benzazepines have high intrinsic activity whereas others do not. In 2015 the first positive allosteric modulator ... Benzazepine derivatives SCH-23,390 - 100-fold selectivity for D1 over D5 Ecopipam (SCH-39,166) - a selective D1/D5 antagonist ... the D5 receptor, but the benzazepines generally are more selective for the D1 and D5 receptors versus the D2-like family. ... To date, most of the known ligands are based on dihydrexidine or the prototypical benzazepine partial agonist SKF-38393 (one ...

Treatment of these compounds with TBAF invokes a ring-expansion that provides the corresponding benzazepines. One variation of ... "Tetrahydroquinolines and Benzazepines through Catalytic Diastereoselective Formal [4 + 2]-Cycloaddition Reactions between Donor ...

It is a benzazepine derivative structurally related to the anorectic drug lorcaserin. It is selective for 5-HT2A, with an EC50 ... Benzazepines, O-methylated phenols, All stub articles, Nervous system drug stubs). ...

... is a synthetic benzazepine derivative used in scientific research which acts as an agonist at the D1-D2 dopamine ... 5-tetrahydro-1H-3-benzazepines". Journal of Medicinal Chemistry. 25 (4): 352-358. doi:10.1021/jm00346a005. PMID 7069713. Lee SM ... 5-tetrahydro-1H-3-benzazepines, GSK plc brands, D1-receptor agonists, D2-receptor agonists, Catechols, Chloroarenes, Potassium ...

5-tetrahydro-1H3-benzazepines". Journal of Heterocyclic Chemistry. 9 (3): 609-616. doi:10.1002/jhet.5570090322. Trachsel D, ...

... is a synthetic compound of the benzazepine class that acts as a D1/D5 receptor full agonist. SKF-82,958 and similar ... 1982). "Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines". Journal of Medicinal ... 5-tetrahydro-1H-3-benzazepines, Synthetic estrogens, GSK plc brands, D1-receptor agonists, D5 receptor agonists, Phenols, ...

5-tetrahydro-1H-3-benzazepines, Abandoned drugs, Benzazepines, D1-receptor agonists, All stub articles, Pharmacology stubs). ... Trepipam (INN) is a dopamine receptor agonist of the benzazepine group that was never marketed. It acts specifically as an ...

A series of 3-benzazepine derivatives, such as Lorcaserin (Figure 6) have been evaluated for their potency and selectivity for ... "Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity". ...

Pyridine derivatives with benzazepine have stronger selectivity and anti-tumor activity and less toxic side effects. They ... Compounds with no fluorine atom in the benzazepine inhibit multiple targets and have better in vitro enzyme inhibiting activity ...

March 2005). "Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of ... January 2008). "Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine ( ... partial agonist at 5-HT2A Some benzazepines and similar compounds related to lorcaserin such as SCHEMBL5334361 are potent 5- ...

March 2005). "Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of ... January 2008). "Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine ( ... "Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases", published 2004-16-06, ...

3 (6). Sebastian J (2016). "Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose ...

5-methano-1H-3-benzazepine Vionnet JP, Renaud P (1994). "Facile Preparation of (-)-12-Epiprostaglandins from 7-Oxabicyclo[2.2.1 ...

... mesylate (Corlopam) is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial ... 5-tetrahydro-1H-3-benzazepines, D1-receptor agonists, Catechols, Chloroarenes, Peripherally selective drugs). ...

... is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist. ... 5-tetrahydro-1H-3-benzazepines, GSK plc brands, D1-receptor agonists, D5 receptor agonists, Catechols, All stub articles, ...

... (INN; PR 786-723) is an opioid analgesic of the benzazepine class which was developed by Pentwell in the 1960s but was ...

Benzazepine derivatives: SKF-83,959 (2013) & Nor-Trepipam [20569-49-7]: Various phenyltropanes, such as WF-23, dichloropane, ...

Benzazepines, Vasopressin receptor antagonists, 2-Tolyl compounds, All stub articles, Antihypertensive agent stubs). ...

5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue". Journal of Medicinal Chemistry. 35 (8): 1466-71. doi:10.1021/ ... 5-tetrahydro-1H-3-benzazepines, Dopamine agonists, Bromoarenes, Allylamines, Benzazepanes, All stub articles, Gastrointestinal ...

Benzazepines, Heterocyclic compounds with 3 rings, All stub articles, Organic compound stubs). ...

5-tetrahydro-1H-3-benzazepines, Chloroarenes, All stub articles, Nervous system drug stubs). ...