... (Apo-CII, or Apoc-II), or apolipoprotein C2 is a protein that in humans is encoded by the APOC2 gene. The ... 1989). "A deletion mutation in the ApoC-II gene (ApoC-II Nijmegen) of a patient with a deficiency of apolipoprotein C-II". J. ... 1988). "Donor splice site mutation in the apolipoprotein (Apo) C-II gene (Apo C-IIHamburg) of a patient with Apo C-II ... 1989). "A nonsense mutation in the apolipoprotein C-IIPadova gene in a patient with apolipoprotein C-II deficiency". J. Clin. ...

Brewer HB, Lux SE, Ronan R, John KM (May 1972). "Amino acid sequence of human apoLp-Gln-II (apoA-II), an apolipoprotein ... Lackner KJ, Law SW, Brewer HB (Sep 1984). "Human apolipoprotein A-II: complete nucleic acid sequence of preproapo A-II". FEBS ... Remarkably, defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. ApoA-II has been shown ... Apolipoprotein A-II is a protein that in humans is encoded by the APOA2 gene. It is the second most abundant protein of the ...

... even if they have two ApoE4 alleles, thus reducing the risk from nine or ten times the odds of getting AD down to just two ... The gene, APOE, is mapped to chromosome 19 in a cluster with apolipoprotein C1 (APOC1) and the apolipoprotein C2 (APOC2). The ... "Genetic studies of human apolipoproteins. X. The effect of the apolipoprotein E polymorphism on quantitative levels of ... Yet those with two ε4 alleles have up to 20 times the risk of developing AD. There is also evidence that the APOE2 allele may ...

"Plasma apolipoprotein concentrations in familial apolipoprotein A-I and A-II deficiency (Tangier disease)". Metabolism: ... Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E, and apolipoprotein A-I". The Journal of Biological ... Apolipoprotein D (ApoD) is a component of HDL that has no marked similarity to other apolipoprotein sequences. It has a high ... "Entrez Gene: APOD apolipoprotein D". Muffat J, Walker DW (January 2010). "Apolipoprotein D: an overview of its role in aging ...

These two activities can be differentiated by the binding to Apo-H domains, whereas binding to the 5th domain promotes that ... 2000). "HLA class II alleles associations of anticardiolipin and anti-beta2GPI antibodies in a large series of European ... In autoimmune disease, anti-apolipoprotein H (AAHA) antibodies, also called anti-β2 glycoprotein I antibodies, comprise a ... 70 (2): 342-5. doi:10.1055/s-0038-1649577. PMID 8236146. Schousboe I, Rasmussen MS (1995). "Synchronized inhibition of the ...

Zannis VI, Cole FS, Jackson CL, Kurnit DM, Karathanasis SK (Jul 1985). "Distribution of apolipoprotein A-I, C-II, C-III, and E ... Apolipoprotein C-III also known as apo-CIII, and apolipoprotein C3, is a protein that in humans is encoded by the APOC3 gene. ... Karathanasis SK (Oct 1985). "Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV ... "Two initiator-like elements are required for the combined activation of the human apolipoprotein C-III promoter by upstream ...

... is the primary apolipoprotein of chylomicrons, VLDL, Lp(a), IDL, and LDL particles (LDL-commonly known as "bad ... Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. It is commonly used to detect risk of ... Su Q, Tsai J, Xu E, Qiu W, Bereczki E, Santha M, Adeli K (2009). "Apolipoprotein B100 acts as a molecular link between lipid- ... MedlinePlus Encyclopedia: Apolipoprotein B100 Cromwell WC, Otvos JD, Keyes MJ, Pencina MJ, Sullivan L, Vasan RS, Wilson PW, ...

... C (ApoC-I, apo ApoC-II, apo ApoC-III, and ApoC-IV) Apolipoprotein D Apolipoprotein E Apolipoprotein F ... Apolipoprotein H - a misnomer Apolipoprotein L Apolipoprotein M Apolipoprotein(a) Exchangeable apolipoproteins (apoA, apoC, and ... HuGENet Review Apolipoprotein AI Mutations and Information Apolipoproteins. Apo A1, B, C2. Apolipoproteins information This ... apolipoprotein C-II for lipoprotein lipase and apolipoprotein A-I (apoA1) for lecithin-cholesterol acyltransferase).[citation ...

Lately,[when?] two novel susceptibility haplotypes i.e. P2-S2-X1 and P1-S2-X1 have been discovered in ApoAI-CIII-AIV gene ... Apolipoprotein AI (Apo-AI) is a protein that in humans is encoded by the APOA1 gene. As the major component of HDL particles, ... The encoded apolipoprotein AI, is a 28.1 kDa protein composed of 243 amino acids; 21 peptides have been observed through mass ... Apolipoprotein AI has also been isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect ...

... is a protein that in humans is encoded by the APOL1 gene. Two transcript variants encoding two different ... G2 is an in-frame deletion of the two amino acid residues, N388 and Y389.[citation needed] Apolipoprotein L1 (apoL1) is a minor ... Recently, two coding sequence variants in APOL1 have been shown to associate with kidney disease in a recessive fashion while ... APOL1 is a member of a family of apolipoproteins which also includes six other proteins and it is a member of bcl2 genes which ...

Retinyl esters (present in meats) and beta-carotene (present in plants) are the two main sources of retinoids in the diet. ... apolipoprotein D; beta-lactoglobulin; complement component C8 gamma chain; crustacyanin; epididymal-retinoic acid binding ... In the event that two species names have identical designations, they are discriminated from one another by adding one or more ... share only one or two of these. Proteins known to belong to this family include alpha-1-microglobulin (protein HC); major ...

Kim DH, Iijima H, Goto K, Sakai J, Ishii H, Kim HJ, Suzuki H, Kondo H, Saeki S, Yamamoto T (Jun 1996). "Human apolipoprotein E ... Upon reelin binding, Dab1 is phosphorylated by two tyrosine kinases, Fyn and Src. The phosphorylated Dab1 then causes further ... Apolipoprotein E (ApoE) plays an important role in phospholipid and cholesterol homeostasis. After binding ApoER2, ApoE is ... Riddell DR, Sun XM, Stannard AK, Soutar AK, Owen JS (2001). "Localization of apolipoprotein E receptor 2 to caveolae in the ...

1996). Apolipoprotein E and Alzheimer's Disease. Research and Perspectives in Alzheimer's Disease. Berlin, Heidelberg: Springer ... "Maestre CV" (PDF). Maestre, Gladys Elena (1996). Apolipoproteins and Alzheimer's disease (Thesis). OCLC 36257436. Staff, M. D. ... "The apolipoprotein ?4 allele in patients with Alzheimer's disease". Annals of Neurology. 34 (5): 752-754. doi:10.1002/ana. ... "Apolipoprotein E and alzheimer's disease: Ethnic variation in genotypic risks". Annals of Neurology. 37 (2): 254-259. doi: ...

Apolipoprotein L2 is a protein that in humans is encoded by the APOL2 gene. This gene is a member of the apolipoprotein L gene ... Two transcript variants encoding the same protein have been found for this gene. >sp,Q9BQE5,1-337 ... "Entrez Gene: APOL2 apolipoprotein L, 2". "The Human Protein atlas Gene: APOL2 apolipoprotein L, 2". Liao W, Goh FY, Betts RJ, ... "The Human Protein atlas Gene: APOL2 apolipoprotein L, 2". Rao SK, Pavicevic Z, Du Z, Kim JG, Fan M, Jiao Y, Rosebush M, Samant ...

Apolipoprotein L6 is a protein that in humans is encoded by the APOL6 gene. This gene is a member of the apolipoprotein L gene ... Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome ... "Entrez Gene: APOL6 apolipoprotein L, 6". Human APOL6 genome location and APOL6 gene details page in the UCSC Genome Browser. ... Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA (Jan 2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, ...

However, the two models do not have the same meaning and can be falsified based on data (that is, if observational data show an ... Katan MB (March 1986). "Apolipoprotein E isoforms, serum cholesterol, and cancer". Lancet. 1 (8479): 507-8. doi:10.1016/s0140- ... Where two models match on all relevant variables and data from one model is known to be unbiased, data from one population can ... The two effects have a common cause. There exists a (non-causal) spurious correlation between A {\displaystyle A} and C {\ ...

Zannis VI, Kan HY, Kritis A, Zanni E, Kardassis D (Mar 2001). "Transcriptional regulation of the human apolipoprotein genes". ... two mechanisms for repression". Molecular and Cellular Biology. 20 (1): 187-95. doi:10.1128/MCB.20.1.187-195.2000. PMC 85074. ... Ginsburg GS, Ozer J, Karathanasis SK (Jul 1995). "Intestinal apolipoprotein AI gene transcription is regulated by multiple ... "Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human ...

... and apolipoprotein E receptor-2 (ApoER2; 602600), are also required. Both receptors bound Dab1 on their cytoplasmic tails and ... "Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E ... 19 (2): 239-49. doi:10.1016/S0896-6273(00)80936-8. PMID 9292716. S2CID 1273677. Long H, Bock HH, Lei T, Chai X, Yuan J, Herz J ... 47 (2): 165-74. doi:10.1002/gcc.20519. PMID 18008369. S2CID 24674687. Deguchi K, Inoue K, Avila WE, et al. (2003). "Reelin and ...

Zannis VI, Kan HY, Kritis A, Zanni E, Kardassis D (March 2001). "Transcriptional regulation of the human apolipoprotein genes ... The name is a combination of the two. During Drosophila research, it was found that a mutation in the gene MAD in the mother ... MAD homolog 2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against ... 11 (1-2): 5-13. doi:10.1016/S1359-6101(99)00024-6. PMID 10708948. Miyazono K (2000). "TGF-beta signaling by Smad proteins". ...

Thus one extra sialyl residue on apolipoprotein C3 impairs its action on lipoprotein lipase. This can affect expression of the ... Galton, DJ (August 2017). "Clarifying complex inheritance: apolipoprotein C3 and atherosclerosis". Current Opinion in ... "An abnormal triglyceride-rich lipoprotein containing excess sialylated apolipoprotein". Journal of Clinical Investigation. 69 ( ... "Hypertriglyceridaemia associated with an abnormal triglyceride-rich lipoprotein carrying excess apolipoprotein". Lancet. 2 ( ...

Apolipoprotein M is an apolipoprotein and member of the lipocalin protein family that in humans is encoded by the APOM gene. It ... Two transcript variants encoding two different isoforms have been found for this gene, but only one of them has been fully ... "The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma ... "Entrez Gene: APOM apolipoprotein M". Christoffersen C, Ahnström J, Axler O, Christensen EI, Dahlbäck B, Nielsen LB (July 2008 ...

Ferrous ion is a common nomenclature used in the HMOX field for Iron(II) which appears in PubChem. The iron liberated from HMOX ... peptides such as adrenomedullin and apolipoprotein; and iii) hemin. NRF2 inducers with downstream HO-1 induction include: ... Endogenous inducers include i) lipids such as lipoxin and epoxyeicosatrienoic acid; and ii) ... HO-2 is encoded by the HMOX2 gene. HO-2 is 36 kDa and shares 47% similarity with the HO-1 amino acid sequence; notably HO-2 has ...

"Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene". The Journal of Biological ... Servillo L, Brewer HB, Osborne JC (February 1981). "Evaluation of the mixed interaction between apolipoproteins A-II and C-I ... Curry MD, McConathy WJ, Fesmire JD, Alaupovic P (April 1981). "Quantitative determination of apolipoproteins C-I and C-II in ... Rozek A, Buchko GW, Cushley RJ (June 1995). "Conformation of two peptides corresponding to human apolipoprotein C-I residues 7- ...

Seol W, Choi HS, Moore DD (Jan 1995). "Isolation of proteins that interact specifically with the retinoid X receptor: two novel ... "Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression". Gastroenterology. 125 (2): 544-55. doi:10.1016/ ... Seol W, Choi HS, Moore DD (Jan 1995). "Isolation of proteins that interact specifically with the retinoid X receptor: two novel ... 290 (1-2): 35-43. doi:10.1016/S0378-1119(02)00557-7. PMID 12062799. Pineda Torra I, Claudel T, Duval C, Kosykh V, Fruchart JC, ...

Dance GS, Sowden MP, Cartegni L, Cooper E, Krainer AR, Smith HC (2002). "Two proteins essential for apolipoprotein B mRNA ... Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 also known as C->U-editing enzyme APOBEC-1 is a protein that in ... Like all APOBEC proteins, A1 coordinates a zinc atom with two cysteine and one histidine residues that serve as a Lewis acid. ... Lau PP, Chang BH, Chan L (April 2001). "Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec ...

Two transcription initiation sites and two polyadenylation sites are identified in the gene structure. The reelin protein ... All members of this family are receptors for Apolipoprotein E (ApoE). Therefore, they are often synonymously referred to as ' ... Moreover, the two main receptors of reelin are able to form clusters that most probably play a major role in the signaling, ... The two main reelin receptors seem to have slightly different roles: VLDLR conducts the stop signal, while ApoER2 is essential ...

A specific isoform of apolipoprotein, APOE4, is a major genetic risk factor for Alzheimer's disease. While apolipoproteins ... Two other genes associated with autosomal dominant Alzheimer's disease are ABCA7 and SORL1. Alleles in the TREM2 gene have been ... Nevertheless, two-thirds of nursing home residents have dementias. Dementia caregivers are subject to high rates of physical ... APOEε4 is one of four alleles of apolipoprotein E (APOE). APOE plays a major role in lipid-binding proteins in lipoprotein ...

2002). "Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical ... Apolipoprotein C-IV, also known as apolipoprotein C4, is a protein that in humans is encoded by the APOC4 gene. APOC4 is a ... in the apolipoprotein E, C-I, and C-II gene locus". Genomics. 28 (2): 291-300. doi:10.1006/geno.1995.1144. PMID 8530039. Human ... "Entrez Gene: apolipoprotein C-IV". Allan CM, Walker D, Segrest JP, Taylor JM (July 1995). "Identification and characterization ...

The HDL donates apolipoprotein C-II (APOC2) and apolipoprotein E (APOE) to the nascent chylomicron and, thus, converts it to a ... The main apolipoprotein component is ApoB48. While circulating in blood, chylomicrons exchange components with high-density ... The triglycerides are then combined with phospholipids, cholesteryl esters, and apolipoprotein B48 (ApoB48) to form a nascent ... These triglycerides, along with phospholipids and cholesterol, are added to apolipoprotein B48 to form immature chylomicrons. ...

Kim SY, Park SM, Lee ST (January 2006). "Apolipoprotein C-II is a novel substrate for matrix metalloproteinases". Biochem. ... Two molecules of ApoC-II can attach to each LPL dimer. It is estimated that up to forty LPL dimers may act simultaneously on a ... In the Golgi apparatus, the oligosaccharides are further altered to result in either two complex chains, or two complex and one ... "Activation of lipoprotein lipase by native and synthetic fragments of human plasma apolipoprotein C-II". Proc. Natl. Acad. Sci ...