Human platelet antigens (HPA) are polymorphisms in platelet antigens. These can stimulate production of alloantibodies (that is ... "Nomenclature of human platelet antigens". Vox Sang. 85 (3): 240-5. doi:10.1046/j.1423-0410.2003.00331.x. PMID 14516468. S2CID ... http://www.ebi.ac.uk/ipd/hpa/ Human+Platelet+Antigens at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ... antibodies against other people's antigens) in recipients of transfused platelets from donors with different HPAs. These ...

Tuszynski GP, Bevacqua SJ, Schmaier AH, Colman RW, Walsh PN (Jun 1982). "Factor XI antigen and activity in human platelets". ... In humans, Factor XI is encoded by the F11 gene. Factor XI (FXI) is produced by the liver and circulates as a homo-dimer in its ... Kato A, Asakai R, Davie EW, Aoki N (1989). "Factor XI gene (F11) is located on the distal end of the long arm of human ... Fujikawa K, Chung DW, Hendrickson LE, Davie EW (May 1986). "Amino acid sequence of human factor XI, a blood coagulation factor ...

"Purification and partial characterization of CD9 antigen of human platelets". FEBS Letters. 264 (2): 270-4. doi:10.1016/0014- ... by use of human specific DNA probes". Human Genetics. 86 (3): 268-72. doi:10.1007/bf00202407. PMID 1997380. S2CID 27178985. ... Ninomiya H, Sims PJ (July 1992). "The human complement regulatory protein CD59 binds to the alpha-chain of C8 and to the "b" ... Benoit P, Gross MS, Frachet P, Frézal J, Uzan G, Boucheix C, Nguyen VC (January 1991). "Assignment of the human CD9 gene to ...

Generated platelets demonstrated an 85% reduction in class I HLA antigens. These platelets appeared to have normal function in ... DC-like antigen-presenting cells obtained from human induced pluripotent stem cells can serve as a source for vaccination ... Thus, the ability to generate platelet products ex vivo and platelet products lacking HLA antigens in serum-free media would ... The fact that human iPSCs are capable of forming teratomas not only in humans but also in some animal body, in particular mice ...

"Entrez Gene: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)". May, K. E.; Villar, J.; Kirtley, S.; Kennedy, ... Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation ... CD61+Antigens at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ITGB3 Info with links in the Cell ... Bennett JS (2001). "Platelet-fibrinogen interactions". Ann. N. Y. Acad. Sci. 936 (1): 340-54. Bibcode:2001NYASA.936..340B. doi: ...

"The structure and function of the molecules that carry human red blood cell and platelet antigens". Transfusion Medicine ... Approximately 25 of these membrane proteins carry the various blood group antigens, such as the A, B and Rh antigens, among ... there are about 4,000-11,000 white blood cells and about 150,000-400,000 platelets per microliter. Human red blood cells take ... lack of Kx antigen and greatly reduced expression of Kell antigens); RhD/RhCE - defines Rh Blood Group and the associated ...

Davoren A, Curtis BR, Aster RH, McFarland JG (August 2004). "Human platelet antigen-specific alloantibodies implicated in 1162 ... Platelet antigens are inherited from both mother and father. NAIT is caused by antibodies specific for platelet antigens ... NAIT, hence, is caused by transplacental passage of maternal platelet-specific alloantibody and rarely human leukocyte antigen ... "Alloimmunization to platelet antigen HPA-1a (PIA1) is strongly associated with both HLA-DRB3*0101 and HLA-DQB1*0201". Human ...

Shiga Toxin Binds Human Platelets Via Globotriaoslyceramide (Pk antigen) and a Novel Platelet Glycosphingolipid. Infect Immun ... The GLOB antigen (formerly P) is now the member of the separate GLOB blood group system. The P1PK antigens are carbohydrate ... The P antigen (later renamed P1) was first described by Karl Landsteiner and Philip Levine in 1927. The P1PK blood group system ... Rare p phenotype (absence of P1PK antigens caused by null mutations in A4GALT): anti-P1 (-), anti-P (-), anti-PP1Pk (-), and ...

... and activated platelets (Lin et al., 2002). In addition, the platelet-specific Gov antigen system (HPA15), implicated in ... CD109+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD109 genome location and CD109 ... CD109 (Cluster of Differentiation 109) is a human gene. CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute ... Lewandrowski U, Moebius J, Walter U, Sickmann A (2006). "Elucidation of N-glycosylation sites on human platelet proteins: a ...

Collecting the platelets from a single donor also simplifies human leukocyte antigen (HLA) matching, which improves the chance ... platelet increment at one hr x BSA (m2) / # platelets infused x 1011 Expected platelet increase (per μL) = platelets infused x ... Platelet count increase as well as platelet survival after transfusion is related to the dose of platelets infused and to the ... Not all platelet transfusions use platelets collected by automated apheresis. The platelets can also be separated from ...

1989). "A new platelet-specific antigen, Naka, involved in the refractoriness of HLA-matched platelet transfusion". Vox ... Other human scavenger receptors related to CD36 are SCARB1 and SCARB2 proteins. Cluster of differentiation CD36 antigen GRCh38 ... CD36 is also known as glycoprotein IV (gpIV) or glycoprotein IIIb (gpIIIb) in platelets and gives rise to the Naka antigen. The ... Subsequent studies have shown that CD36 found on the surface of platelets. This antigen is recognized by the monoclonal ...

"Fya/Fyb antigen polymorphism in human erythrocyte Duffy antigen affects susceptibility to Plasmodium vivax malaria". Proc Natl ... "Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum". Science. 338 (6112): 1348-51. ... "Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum". Science. 338 (6112): 1348-51. ... DARC+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Duffy at BGMUT Blood Group Antigen ...

Human CD Antigen Chart (eBioscience) Mouse CD Antigen Chart (eBioscience) Human PECAM1 genome location and PECAM1 gene details ... Almendro N, Bellón T, Rius C, Lastres P, Langa C, Corbí A, Bernabéu C (December 1996). "Cloning of the human platelet ... Kirschbaum NE, Gumina RJ, Newman PJ (December 1994). "Organization of the gene for human platelet/endothelial cell adhesion ... "Platelet-endothelial cell adhesion molecule-1 is expressed by a subpopulation of human trophoblasts: a possible mechanism for ...

... +protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD84 genome location and ... "Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling". Blood. 106 (9): 3028-34. doi: ... de la Fuente MA, Pizcueta P, Nadal M, Bosch J, Engel P (Sep 1997). "CD84 leukocyte antigen is a new member of the Ig ... Tangye SG, van de Weerdt BC, Avery DT, Hodgkin PD (Jun 2002). "CD84 is up-regulated on a major population of human memory B ...

Antigen determinants that possess type-specific reactivity are found on the envelope. Antigen determinants that possess type- ... in humans and other mammalian species. The genus includes the human immunodeficiency virus (HIV), which causes AIDS. ... For example, a model of mouse hemophilia is corrected by expressing wild-type platelet-factor VIII, the gene that is mutated in ... Some groups have cross-reactive gag antigens (e.g., the ovine, caprine, and feline lentiviruses). Antibodies to gag antigens in ...

... platelet refractoriness Pathogen-reduced platelet component Alloantibodies to platelet antigens Human leucocyte antigen (HLA) ... antibodies Human platelet antigen (HPA) antibodies Immune complexes Other antibodies Drug-related antibodies Platelet ... PI = post-transfusion platelet count - pre-transfusion platelet count However, it is affected by the number of platelets given ... platelet component ABO mismatch between platelet component and recipient Number of platelets within the component if platelet ...

If the recipient has antibodies against human leukocyte antigens (HLA), proteins found on the surface of white blood cells, the ... and reduce the efficacy of platelet transfusions and allogeneic stem cell transplants. In a 1934 experiment, Strumia gave ... Finally, people who receive granulocyte transfusions may develop antibodies against the human leukocyte antigens found on the ... and the development of antibodies against human leukocyte antigens, which can interfere with subsequent transfusions. ...

SUCNR1 is one of the highest expressed G protein-coupled receptors on human platelets, present at levels similar to P2Y12, ... Succinate may enhance adaptive immunity by triggering the activity of antigen-presenting cells that, in turn, activate T-cells ... In humans, three HIF prolyl 4-hydroxylases regulate the stability of HIFs. Hydroxylation of two prolyl residues in HIF1α ... This pathway is exploited in metabolic engineering to net generate succinate for human use. Additionally, succinic acid ...

Human Lymphocyte Antigens or HLAs), and the transfusion of platelets and later stem cells in the treatment of leukaemia. He ... He performed early work on the typing of red cells and their antigens, white blood cells ( ...

CD49b+antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) PDBe-KB provides an overview of all the ... structure information available in the PDB for Human Integrin alpha 2 Moroi M, Jung SM (1997). "Platelet receptors for collagen ... Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. The ... They are found on a wide variety of cell types including T cells (the NKT cells), NK cells, fibroblasts and platelets. ...

... a unit of pressure Human platelet antigen Human Protein Atlas Hydrogen pinch analysis Hypothalamic-pituitary-adrenal axis in ... UK polo governing body HPA Toucan human-powered aircraft built by Hertfordshire Pedal Aeronauts Hans Peter Anvin (born 1972), ... physiology High-performance addressing, in LCD displays Host protected area of computer data storage Human-powered aircraft ...

... platelets, monocytes and T cells. DNAM-1 gene CD226 is conserved between human and mice. In humans the CD226 gene is located on ... CD226 (Cluster of Differentiation 226), PTA1 (outdated term, 'platelet and T cell activation antigen 1') or DNAM-1 (DNAX ... CD226+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD226 genome location and ... 2006). "Expression of human CD226 on T cells and natural killer cells and of soluble CD226 in plasma of HIV-1-infected Chinese ...

... human platelet antigen). Recipients who lack this protein develop sensitization to this protein from prior transfusions or ... Antibodies to human neutrophil antigens (HNA) and human leukocyte antigens (HLA) have been associated with this type of ... Fast LD, DiLeone G, Marschner S (July 2011). "Inactivation of human white blood cells in platelet products after pathogen ... Although transfusions of platelets are far less numerous (relative to RBC), platelet storage lesion and resulting efficacy loss ...

... and the antigen-presenting dendritic cells in both mice and humans. Binding of antigens to IgE already bound by the FcεRI on ... Fc receptors are also found on eosinophils, monocytes, macrophages and platelets in humans. There are two types of Fcε ... IgE also plays a pivotal role in responses to allergens, such as: anaphylactic reactions to drugs, bee stings, and antigen ... Rihet P, Demeure CE, Bourgois A, Prata A, Dessein AJ (November 1991). "Evidence for an association between human resistance to ...

In humans, the HLAs corresponding to MHC class I are HLA-A, HLA-B, and HLA-C. Class I MHC molecules bind peptides generated ... Histocompatibility+Antigens+Class+I at the U.S. National Library of Medicine Medical Subject Headings (MeSH) MHC+Class+I+Genes ... They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of proteins from ... It is likely that human MHC class Ib loci (HLA-E, -F, and -G) as well as MHC class I pseudogenes arose from MHC class Ia loci ( ...

The gene for human PF4 is located on human chromosome 4. Platelet factor-4 is a 70-amino acid protein that is released from the ... PF4 complex is the antigen in heparin-induced thrombocytopenia (HIT), an idiosyncratic autoimmune reaction to the ... Han ZC, Bellucci S, Tenza D, Caen JP (April 1990). "Negative regulation of human megakaryocytopoiesis by human platelet factor ... The human platelet factor 4 kills malaria parasites within erythrocytes by selectively lysing the parasite's digestive vacuole ...

The human IL-3 gene encodes a protein 152 amino acids long, and the naturally occurring IL-3 is glycosylated. The human IL-3 ... It also has many more specific effects like the regeneration of platelets and potentially aids in early antibody isotype ... IL-3 is produced by T cells only after stimulation with antigens or other specific impulses. However, it was observed that IL-3 ... "Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors". Cell ...

Qiu M, Hua S, Agrawal M, Li G, Cai J, Chan E, Zhou H, Luo Y, Liu M (Dec 1998). "Molecular cloning and expression of human grap- ... "Expression of the Grb2-related protein of the lymphoid system in B cell subsets enhances B cell antigen receptor signaling ... Platelets. 13 (8): 459-64. doi:10.1080/0953710021000059431. PMID 12487779. S2CID 26192685. Yankee TM, Solow SA, Draves KD, ... Xia C, Bao Z, Tabassam F, Ma W, Qiu M, Hua S, Liu M (Jul 2000). "GCIP, a novel human grap2 and cyclin D interacting protein, ...

CD51+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ITGAV Info with links in the Cell ... Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. ITGAV encodes integrin alpha chain V. Integrins are ... "Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet ... "Entrez Gene: ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)". Hermann P, Armant M, Brown E, ...

"Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen". European Journal of ... "Anticoagulant and antithrombotic properties of platelet protease nexin-1". Blood. 115 (1): 97-106. doi:10.1182/blood-2009-04- ... The human Protein C inhibitor have 19 amino acid signal peptide. The study of genomic DNA by restriction mapping, polymerase ... Yasuda T, Nadano D, Iida R, Tanaka Y, Nakanaga M, Kishi K (May 1992). "Discovery of a genetic polymorphism of human plasma ...