Unlike myeloid dendritic cells, myeloid antigens like CD11b, CD11c, CD13, CD14 and CD33 are not present on pDC surfaces. ... In humans, pDCs exhibit plasma cell morphology and express CD4, HLA-DR, CD123, blood-derived dendritic cell antigen-2 (BDCA-2 ... Villadangos, José A.; Young, Louise (September 2008). "Antigen-Presentation Properties of Plasmacytoid Dendritic Cells". ... which allows the cell to optimize its antigen-presenting abilities. MHC class I on pDC surfaces are able to activate CD8+ T ...

The hairy cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103, and FMC7 antigens. (CD103, CD22, ... and CD11c are strongly expressed.) Hairy cell leukemia-variant (HCL-V), which shares some characteristics with B cell ... usually showing a common Human Leukocyte Antigen (HLA) type. The Hairy Cell Leukemia Consortium was founded in 2008 to address ...

Dendritic cells (DCs) are antigen presenting cells for the induction of antigen specific T cell response. DC-based ... are derived from myeloid progenitor cells in the bone marrow and are characterized by expression of CD11c. cDCs can be ... The most critical step in vaccination is the effective presentation of cancer antigens to T cells, and because of DCs are the ... Non-activated (immature) DCs are usually located in the peripheral non-lymphoid tissues and they can present self-antigens to T ...

... one of its key identifiers is the absence in expression of the surface antigens CD10, CD11c, CD25, CD103 and cyclin D1 - an ... B-lymphocytes have two responsibilities: Production of antibodies - In response to antigens, B-lymphocytes produce and release ... b-lymphocyte surface antigens CD19, CD20, CD22, CD79a and FMC7, and weak expression of CD5 and CD23. Due to the similarities ... Interactions between antibodies and antigens allow B-lymphocytes to establish cellular memories, otherwise known as immunities ...

CD11c+Antigens at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Mouse CD Antigen Chart Human CD Antigen ... CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c . ... CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages ... Bilsland CA, Diamond MS, Springer TA (1994). "The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by ...

... present on macrophages that is also called Macrophage-1 antigen (CR3) and αMβ2 integrin. CD11c/CD18 also called complement ... For example, LFA1 (CD11a/CD18) short representation of Lymphocyte Function-associated Antigen 1, also called αLβ2 integrin Mac1 ...

... antigens, cd11a MeSH D23.050.301.264.035.111.049 - antigens, cd11b MeSH D23.050.301.264.035.111.074 - antigens, cd11c MeSH ... antigens, cd11a MeSH D23.101.100.110.111.049 - antigens, cd11b MeSH D23.101.100.110.111.074 - antigens, cd11c MeSH D23.101. ... antigens, cd15 MeSH D23.101.100.900.131 - antigens, cd31 MeSH D23.101.100.920 - antigens, ly MeSH D23.101.100.930 - antigens, ... forssman antigen MeSH D23.050.285.018 - antigens, cd24 MeSH D23.050.285.025 - antigens, cd30 MeSH D23.050.285.040 - antigens, ...

... specifically those that target self-antigens. One example is antigen-specific CD4+ T cell tolerance, which serves as the ... In a mammary carcinoma model, depletion of CD25+ regulatory T cells increase the amount of CD8+CD11c+PD110, which target and ... However, in some cases, selective CD4+ T cell tolerance provides a unique therapeutic opportunity to maximize self antigen- ... targeted immune and antitumor responses without inducing autoimmunity by incorporating self antigen-independent CD4+ T cell ...

CD18+antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ITGB2 Info with links in the Cell ... The known binding partners of CD18 are CD11a, CD11b, CD11c and CD11d. Binding of CD18 and CD11a results in the formation of ... Huang C, Springer TA (August 1995). "A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) ... LFA-1 is involved in adhesion and binding to antigen presenting cells through interactions with the surface protein ICAM-1. ...

CD18 Macrophage-1 antigen (CR3) - Heterodimer: CD11b / CD18 Integrin alphaXbeta2 (CR4) - Heterodimer: CD11c / CD18 Very late ... Antigen Antigenicity Immunogen Superantigen Allergen Hapten Epitope Linear Conformational Mimotope Tumor antigen Antigen- ... T cells Antigen receptor - T cell receptor (TCR) Subunits - TRA@ / TRB@ / TRD@ / TRG@ Co-receptors CD8 (CD8α / CD8β) CD4 ... CD11c) Beta subunits B1 B2 B3 B4 B5 B6 B7 B8 Dimers Cytoadhesin receptor Integrin alpha6beta4 Glycoprotein IIb/IIIa - ...

Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is ... CD11a has been shown to interact with ICAM-1. CD11c integrin leukocyte adhesion deficiency Cluster of differentiation GRCh38: ... CD11a+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ITGAL Info with links in the Cell ... CD11a is one of the two components, along with CD18, which form lymphocyte function-associated antigen-1. Efalizumab acts as an ...

These cells lack antigen specific B or T cell receptor because of the lack of recombination activating gene. ILC2s produce type ... which produced IL-5 and IL-13 in response to IL-25 and expressed MHC class II and CD11c. In 2006, a similar cell population was ... ILC2s are critical for primary responses to local Th2 antigens e.g. helminths and viruses and that is why ILC2s are abundant in ...

... antigens, cd11a MeSH D12.776.543.750.705.408.100.150 - antigens, cd11b MeSH D12.776.543.750.705.408.100.200 - antigens, cd11c ... antigen, b-cell MeSH D12.776.543.750.705.816.821.500 - antigens, cd79 MeSH D12.776.543.750.705.816.824 - receptors, antigen, t- ... antigens, cd22 MeSH D12.776.543.550.200.124 - antigens, cd24 MeSH D12.776.543.550.200.131 - antigens, cd31 MeSH D12.776.543.550 ... antigens, cd27 MeSH D12.776.543.750.705.852.760.072 - antigens, cd30 MeSH D12.776.543.750.705.852.760.097 - antigens, cd40 MeSH ...

In terms of expression markers, islet macrophages are positive for; F4/80, CD11b, CD11c, MHC-II, CD64, CD68, LyzM (lysozyme), ... The islet resident macrophage was first identified in 1979 as an antigen-presenting cell (APC), which expresses major ... Calderon, B (2014). "The Central Role of Antigen Presentation in Islets of Langerhans in Autoimmune Diabetes". Curr Opin ... Hume, DA (1984). "The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: ...

CD11c−, Gr-1−, NK1.1−, B220−, CD3−, γδTCR−, αβTCR−, α4 and β4-integrin negative. Recently, Heneberg proposed that basophils may ... pollen proteins or helminth antigens). Recent studies in mice suggest that basophils may also regulate the behavior of T cells ...

CD11c− and showed that FABP4-positive TAM subset accumulates in the stroma of mammary tumors, which promote tumor growth ... associated antigen HCA587 and its potential therapeutic strategies. His 2005 collaborative work identified a new CTL epitope, ... "HCA587 Antigen Expression in Normal Tissues and Cancers: Correlation with Tumor Differentiation in Hepatocellular Carcinoma". ... ". "Identification of a new HLA-A*0201-restricted CD8+ T cell epitope from hepatocellular carcinoma-associated antigen HCA587 ...

The antigen is then transferred from CD23+ B cells to CD11c+ antigen presenting cells. The CD11c+ cells in turn present the ... "CD23 regulates monocyte activation through a novel interaction with the adhesion molecules CD11b-CD18 and CD11c-CD18". Immunity ... Antigens which enter the blood stream can be captured by antigen specific IgE antibodies. The IgE immune complexes that are ... "IgE-mediated enhancement of CD4+ T cell responses in mice requires antigen presentation by CD11c+ cells and not by B cells". ...

CD11c, or CD23 cell surface proteins; genomic analyses reveal that these cells contain t(14:18)(q32:q21.3) translocation (85-90 ... lymphocyte function-associated antigen 3, that is involved in activating T-cells), CDKN2A (encoding p16INK4a and p14arf tumor ... infusion of tisagenlecleucel chimeric antigen receptor T cells (i.e. CAR T cells) (i.e. T cells that have been isolated from ...