Anti-cardiolipin antibodies
They are a form of anti-mitochondrial antibody. In SLE, anti-DNA antibodies and anti-cardiolipin antibodies may be present ... Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases, including ... Only a subset of autoimmune anti-cardiolipin antibodies bind Apo-H, these anti-apolipoprotein antibodies are associated with ... because anti-cardiolipin antibodies are present in both conditions, and therefore may tie the two conditions together. Anti- ...
HLA-DR4
"HLA class II alleles associations of anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with ... "HLA class II alleles associations of anticardiolipin antibodies". Lupus. 9 (1): 47-55. doi:10.1177/096120330000900109. PMID ... DRB1*04:02: drug-triggered/idiopathic pemphigus vulgaris, type 1 diabetes, SLE associated anti-cardiolipin and anti-β2 ... glycoprotein I. DRB1*04:03: polycystic ovary syndrome, SLE associated anti-cardiolipin and anti-β2 glycoprotein I. DRB1*04:04: ...
Livedo reticularis
... a rare manifestation of Graves hyperthyroidism associated with anticardiolipin antibodies". South. Med. J. 97 (6): 601-3. doi: ... or blood tests for antibodies associated with antiphospholipid syndrome or systemic lupus erythematosus. Other than identifying ... "Livedo Vasculopathy Associated with IgM Anti-phosphatidylserine-prothrombin Complex Antibody". Acta Dermato Venereologica. 90 ( ... sarcoidosis and Sjögren's syndrome Livedo vasculopathy associated with IgM antiphosphatidylserine-prothrombin complex antibody ...
STING-associated vasculopathy with onset in infancy
... and anticardiolipin antibodies.[citation needed] The erythrocyte sedimentation rate and C reactive protein levels tend to be ...
Takayasu's arteritis
Takayasu arteritis is not associated with ANCA, rheumatoid factor, ANA, and anticardiolipin antibodies. Most people with ...
Osteonecrosis of the jaw
... anticardiolipin antibodies, thrombophilia, and hypofibrinolysis". J Lab Clin Med. 127 (5): 481-8. doi:10.1016/S0022-2143(96) ...
Venereal Disease Research Laboratory test
Kumar KS, Jyothy A, Prakash MS, Rani HS, Reddy PP (2002). "Beta2-glycoprotein I dependent anticardiolipin antibodies and lupus ... It therefore detects anti-cardiolipin antibodies (IgG, IgM or IgA), visualized through foaming of the test tube fluid, or " ... The syphilis anti-cardiolipin antibodies are beta-2 glycoprotein independent, whereas those that occur in antiphospholipid ... "A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but ...
Apolipoprotein H
Shi W, Chong BH, Hogg PJ, Chesterman CN (1993). "Anticardiolipin antibodies block the inhibition by beta 2-glycoprotein I of ... Kumar KS, Jyothy A, Prakash MS, Rani HS, Reddy PP (2002). "Beta2-glycoprotein I dependent anticardiolipin antibodies and lupus ... systemic lupus erythematosus (SLE)). Positivity for anti-cardiolipin antibodies in diagnostic tests for autoimmune ... glycoprotein I identifies a cluster of lysine residues that are critical for phospholipid binding and anti-cardiolipin antibody ...
Alain R. Thierry
"Persistence of neutrophil extracellular traps and anticardiolipin auto‐antibodies in post‐acute phase COVID‐19 patients". ... to be an effect of the persistence of the production of NETs and auto-antibodies. Recently (2022), they have demonstrated ...
Cardiolipin
These antibodies are usually picked up in young women with recurrent spontaneous abortions. In anti-cardiolipin-mediated ... Patients with anti-cardiolipin antibodies (Antiphospholipid syndrome) can have recurrent thrombotic events even early in their ... Hokama Y, Campora CE, Hara C, Kuribayashi T, Le Huynh D, Yabusaki K. Anticardiolipin antibodies in the sera of patients with ... Anti-cardiolipin antibodies can also be increased in numerous other conditions, including systemic lupus erythematosus, malaria ...
Catastrophic antiphospholipid syndrome
An Enzyme-Linked ImmunoSorbent Assay (ELISA) test is done to detect anticardiolipin antibodies' presence in the blood. ... Positive test are often repeated due to the fact that antilipid antibodies can be present in the body for short stints due to ... The syndrome is caused by antiphospholipid antibodies that target a group of proteins in the body that are associated with ... These antibodies activate endothelial cells, platelets, and immune cells, ultimately causing a large inflammatory immune ...
Anti-apolipoprotein antibodies
... also called anti-β2 glycoprotein I antibodies, comprise a subset of anti-cardiolipin antibodies and lupus anticoagulant. These ... Shi W, Chong BH, Hogg PJ, Chesterman CN (1993). "Anticardiolipin antibodies block the inhibition by beta 2-glycoprotein I of ... This contrasts with the major, specific, activity of AAHA, defining a subset of anti-cardiolipin antibodies that specifically ... 2000). "HLA class II alleles associations of anticardiolipin and anti-beta2GPI antibodies in a large series of European ...
Lupus
Another autoantibody finding in SLE is the anti-cardiolipin antibody, which can cause a false positive test for syphilis.[ ... Subtypes of antinuclear antibodies include anti-Smith and anti-double stranded DNA (dsDNA) antibodies (which are linked to SLE ... and anti-histone antibodies (which are linked to drug-induced lupus). Anti-dsDNA antibodies are highly specific for SLE; they ... The anti-dsDNA antibody titers also tend to reflect disease activity, although not in all cases. Other ANA that may occur in ...
HLA-DR52
2000). "HLA class II alleles associations of anticardiolipin and antibeta2GPI antibodies in a large series of European patients ... 01 is weakly associated with anticardiolipin antibodies in SLE DRB3*03:01:DRB1*13:02 may be associated with Crohn's disease HLA ... serum IgG antibodies to Chlamydia pneumoniae with essential hypertension, acute necrotizing encephalopathy DRB3*03: ... "Association of HLA-DRB3*0202 and serum IgG antibodies to Chlamydia pneumoniae with essential hypertension in a highly ...
Lupus headache
... headaches in SLE and associated Raynaud's phenomenon and/or anti-cardiolipin antibodies.[excessive citations] Further studies ... Annese V, Tomietto P, Venturini P, D'Agostini S, Ferraccioli G (2006). "[Migraine in SLE: role of antiphospholipid antibodies ...
Anti-mitochondrial antibody
Anti-cardiolipin antibodies are another type of AMA, and cardiolipin is found on the inner mitochondrial membrane. A cause of ... M1 - cardiolipin (Anti-cardiolipin antibodies, ACA) M2 - branched-chain alpha-keto acid dehydrogenase complex M3 - outer ... had anti-transglutaminase antibodies, usually associated with coeliac disease. Antibodies Mitochondrion MedlinePlus ... and non-species-specific anti-organelle antibody detected by immunofluorescence: the mitochondrial antibody number 5. Clin Exp ...
Cerebritis
The two antibodies implicated are anti-cardiolipin and lupus anticoagulant. Anti-cardiolipin antibodies attach to the ... Anti-neuronal antibodies. The three identified anti-neuronal antibodies postulated in CNS involvement are the lympho-cytotoxic ... These antibodies also correlate with cognitive and visual spatial defects. Second, the anti-neuronal membrane antibodies are ... These antibodies are seen in 90% of SLE patients with psychosis. Antiphospholipid antibodies. ...
Libman-Sacks endocarditis
... presence of anticardiolipin antibodies, arterial and venous thromboses, and neuropsychiatric manifestations of systemic lupus ...
Mixed connective tissue disease
The presence of anticardiolipin antibodies is a more serious risk factor for the disease, as well as the presence of more ... Anti-RNP antibodies in elevated levels, especially antibodies against protein 68 kD. Absence of severe renal or CNS disease. ... SLE, scleroderma, and in MCTD have antibodies against anti-U1-snRNP at differing percentages. These antibodies are in most MCTD ... Distinguishing laboratory characteristics are a positive, speckled anti-nuclear antibody and an anti-U1-RNP antibody. After the ...
Antiphospholipid syndrome
... with all types of antiphospholipid antibody (lupus anticoagulant, anticardiolipin antibody and anti-β2 glycoprotein I antibody ... to detect anti-cardiolipin antibodies or anti-apolipoprotein antibodies.[citation needed] Genetic thrombophilia is part of the ... anti-apolipoprotein antibodies, or anti-cardiolipin antibodies. Antiphospholipid syndrome can be primary or secondary. Primary ... "antiphospholipid antibodies" (anticardiolipin antibodies and lupus anticoagulant) react against proteins that bind to anionic ...
Steven Krilis
"Identification of a region of β2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity" ( ... "A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but ... and a region recognized by anticardiolipin antibodies" (1994) Journal of Immunology, 152 (2), pp. 653-659. Cited 195 times. ... McNeil, H.P., Chesterman, C.N., Krilis, S.A. "Immunology and clinical importance of antiphospholipid antibodies" (1991) ...
Acute esophageal necrosis
Aortic dissection Anti-cardiolipin antibodies CMV infection Herpetic infection Hyperglycemia Hypersensitivity to broad-spectrum ...
Amaurosis fugax
... syndrome Polycythemia Hypercoagulability Protein C deficiency Antiphospholipid antibodies Anticardiolipin antibodies Lupus ... "Amaurosis fugax associated with antiphospholipid antibodies". Annals of Neurology. 25 (3): 228-32. doi:10.1002/ana.410250304. ...
Thrombophilia
... anti-cardiolipin antibodies, and anti-β2-glycoprotein 1 antibodies; it is therefore regarded as an autoimmune disease. In some ... The risk is determined by the subtype of antibody detected, by the antibody titer (amount of antibodies), whether multiple ... anti-cardiolipin antibody, anti-β2 glycoprotein 1 antibody, activated protein C resistance, fibrinogen tests, factor V Leiden ... Recurrent miscarriage is an indication for thrombophilia screening, particularly antiphospholipid antibodies (anti-cardiolipin ...
ACLA
... is an acronym that may refer to: Anti-cardiolipin antibodies Allegheny County Library Association, a library association ...
ACA
... threonine Advisory Committee for Aeronautics Anterior cerebral artery Anti-cardiolipin antibodies Anti-centromere antibodies ...
Dilute Russell's viper venom time
... the other component being the serological testing for anticardiolipin antibodies and anti-β2 glycoprotein-I antibodies using ... Antiphospholipid antibody syndrome is an important marker for recurrent thrombosis, and often warrants indefinite anticoagulant ... This makes the test sensitive to the presence of lupus anticoagulants, because these antibodies interfere with the clot- ... The dRVVT is one component of a workup of a suspected antiphospholipid antibody, ...
Lupus anticoagulant
... lupus anticoagulant is generally tested in conjunction with anti-apolipoprotein antibodies and anti-cardiolipin antibodies, and ... In vivo, the antibodies are thought to interact with platelet membrane phospholipids, increasing adhesion and aggregation of ... Its name is a partial misnomer, as it is actually a prothrombotic antibody in vivo. Lupus anticoagulant in living systems ... The name derives from their properties in vitro, as these antibodies increase coagulation times in laboratory tests such as the ...
ACL
... a common sports injury Anti-cardiolipin antibodies ATP citrate synthase, or ATP citrate lyase, an enzyme ACL Cables, a cable ...
Lupus and pregnancy
... and anticardiolipin antibodies. Neonatal lupus is the occurrence of lupus symptoms in an infant born from a mother with lupus, ... Women pregnant and known to have anti-Ro (SSA) or anti-La antibodies (SSB) often have echocardiograms during the 16th and 30th ... are recommended to be screened for antiphospholipid antibodies, both the lupus anticoagulant (the RVVT and sensitive PTT are ...