... aryl hydrocarbon hydroxylases MeSH D08.244.453.040.050 - aniline hydroxylase MeSH D08.244.453.040.110 - benzopyrene hydroxylase ... aniline hydroxylase MeSH D08.811.682.690.708.170.040.110 - benzopyrene hydroxylase MeSH D08.811.682.690.708.170.040.332 - ... steroid 11-beta-hydroxylase MeSH D08.244.453.915.730 - steroid 12-alpha-hydroxylase MeSH D08.244.453.915.737 - steroid 16-alpha ... hydroxylase MeSH D08.244.453.915.748 - steroid 17-alpha-hydroxylase MeSH D08.244.453.915.760 - steroid 21-hydroxylase MeSH ...
11β-Hydroxylase inhibitors, 21-Hydroxylase inhibitors, Anilines, Antiestrogens, Antiglucocorticoids, Antimineralocorticoids, ... It acts as competitive inhibitor of 11β-hydroxylase, 17α-hydroxylase, 17,20-lyase, 21-hydroxylase, and 3β-hydroxysteroid ... a selective inhibitor of 11β-hydroxylase, which was selected for clinical development and was eventually approved and marketed ...
... and hydroxyflutamide have been found in vitro to inhibit CYP17A1 (17α-hydroxylase/17,20-lyase), an enzyme which is ... Schotten-Baumann reaction between 4-nitro-3-(trifluoromethyl)aniline [393-11-3] (1) with isobutanoyl chloride [79-30-1] (2) in ... Ayub M, Levell MJ (July 1987). "Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens ...
Exposure was primarily to o-toluidine and aniline and a significant increase in incidences of bladder cancer was observed. ... Exposure to o-toluidine enhances the microsomal activity of aryl hydrocarbon hydroxylase (particularly in the kidney), NADPH- ... Anilines, Alkyl-substituted benzenes, IARC Group 1 carcinogens). ...
Serotonin is synthesized from tryptophan by tryptophan hydroxylase, and then further by decarboxylase. A lack of 5-HT at ... Basophilic dyes such as aniline or (weakly) haematoxylin highlight negatively charged components, and so bind to the phosphate ...
It has also been identified in vitro as a strong inhibitor of CYP27A1 (cholesterol 27-hydroxylase) and as an inhibitor of ... or aniline, a diarylpropionamide, and a toluidide. First-generation NSAAs including bicalutamide, flutamide, and nilutamide are ... 27-Hydroxylase inhibitors, Anilides, Anti-acne preparations, Antiprogestogens, AstraZeneca brands, Benzonitriles, Benzosulfones ... CYP46A1 (cholesterol 24-hydroxylase), but this has yet to be assessed or confirmed in vivo or in humans and the clinical ...
... metabolizes mostly small, polar molecules, including toxic laboratory chemicals such as dimethylformamide, aniline, and ... "Replacement of Thr-303 of P450 2E1 with serine modifies the regioselectivity of its fatty acid hydroxylase activity". Journal ...
Vakhitova I, Sadovnikov SV, Iamidanov RS, Seredenin SB (July 2006). "[Cytosine demethylation in the tyrosine hydroxylase gene ... Anilines, Antidepressants, Anxiolytics, Aphrodisiacs, Bromoarenes, Dopamine reuptake inhibitors, Drugs in the Soviet Union, ... and long-lasting upregulation in a variety of brain regions of the expression of tyrosine hydroxylase (TH) and aromatic L-amino ...
... aniline hydroxylase MeSH D12.776.422.220.453.040.110 - benzopyrene hydroxylase MeSH D12.776.422.220.453.040.332 - cytochrome p- ... steroid 11-beta-hydroxylase MeSH D12.776.422.220.453.915.730 - steroid 12-alpha-hydroxylase MeSH D12.776.422.220.453.915.737 - ... steroid 16-alpha-hydroxylase MeSH D12.776.422.220.453.915.748 - steroid 17-alpha-hydroxylase MeSH D12.776.422.220.453.915.760 ... cholesterol 7 alpha-hydroxylase MeSH D12.776.422.220.453.915.212 - cholesterol side-chain cleavage enzyme MeSH D12.776.422.220. ...