"LDL-receptor-related protein 6 is a receptor for Dickkopf proteins". Nature. 411 (6835): 321-5. Bibcode:2001Natur.411..321M. ... Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major ... Actin beta has been shown to interact with SPTBN2. In addition, RNA-binding protein Sam68 was found to interact with the mRNA ... Actin beta is often used in Western blotting as a loading control, to normalize total protein amounts and check for eventual ...
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid ... Schafer DA, Schroer TA (2000). "Actin-related proteins". Annu. Rev. Cell Dev. Biol. 15: 341-63. doi:10.1146/annurev.cellbio. ... Actin-like protein 7A is a protein that in humans is encoded by the ACTL7A gene. ... and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia ...
Liu, S. L; May, J. R; Helgeson, L. A; Nolen, B. J (2013). "Insertions within the actin core of actin-related protein 3 (Arp3) ... An actin nucleation core is a protein trimer with three actin monomers. It is called a nucleation core because it leads to the ... Actin nucleation factors start the polymerization of actin within cells. Many distinct proteins that can mediate the de novo ... Actin protein dimers and trimers are energetically unfavorable.Actin nucleators like the Arp2/3 complex of proteins from the ...
Actin-related protein 3B also known as ARP3-beta is a protein that in humans is encoded by the ACTR3B gene. Pseudogenes of this ... This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid ... "Entrez Gene: ACTR3B ARP3 actin-related protein 3 homolog B (yeast)". Human ACTR3B genome location and ACTR3B gene details page ... the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal ...
Bingham JB, Schroer TA (February 1999). "Self-regulated polymerization of the actin-related protein Arp1". Current Biology. 9 ( ... "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)". ... "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)". ... "Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end". The ...
ActA Actibind Actin Actinfilin Actinogelin Actin-regulating kinases Actin-Related Proteins Actobindin Actolinkin Actopaxin ... Actin-binding proteins (also known as ABPs) are proteins that bind to actin. This may mean ability to bind actin monomers, or ... Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin- ... related to the ERM proteins) Myosins MAP-1C Metavinculin Moesin (the M of ERM proteins) Myosin light chain kinase MAL Mip-90 ...
NPFs in the mammalian cell recruit and bind to the already existing actin-related-protein 2 and 3 complex (Arp2/3 complex) and ... The Actin assembly-inducing protein (ActA) is a protein encoded and used by Listeria monocytogenes to propel itself through a ... an actin monomer binding protein, which itself promotes polymerization at barbed ends of actin filaments. Furthermore, VASP ... In the cytosol they start to polymerize actin on their surface by the help of the ActA protein. It has been shown that ActA is ...
Actin-related protein 2/3 complex subunit 1A is a protein that in humans is encoded by the ARPC1A gene. This gene encodes one ... "Entrez Gene: ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa". Human ARPC1A genome location and ARPC1A gene details ... 1998). "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of ... This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The ...
Actin-related protein 2/3 complex subunit 2 is a protein that in humans is encoded by the ARPC2 gene. This gene encodes one of ... "Entrez Gene: ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa". Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW ... "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily ... "Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex". J ...
2020). "KPTN gene homozygous variant-related syndrome in the northeast of Brazil: A case report". Am J Med Genet A. 182 (4): ... Bearer EL (March 1992). "An actin-associated protein present in the microtubule organizing center and the growth cones of PC-12 ... Bearer EL, Abraham MT (February 1999). "2E4 (kaptin): a novel actin-associated protein from human blood platelets found in ... "Entrez Gene: KPTN kaptin (actin binding protein)". "Body weight data for Kptn". Wellcome Trust Sanger Institute. "Glucose ...
"Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex". Curr. Biol. 17 (7): 579-91. doi:10.1016/j ... Wallar BJ, Deward AD, Resau JH, Alberts AS (2007). "RhoB and the mammalian Diaphanous-related formin mDia2 in endosome ... Protein diaphanous homolog 2 is a protein that in humans is encoded by the DIAPH2 gene. This gene may play a role in the ... Satoh S, Tominaga T (2001). "mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber ...
Neural Wiskott-Aldrich Syndrome Protein (N-WASP). This IcsA/N-WASP complex then activates the Actin-related protein (Arp) 2/3 ... Shigella flexneri is a rod shaped, nonflagellar bacterium that relies on actin-based motility. It produces the protein actin in ... The IcsA protein is first localized to one pole of the bacterium where it will then bind with the host's protein, ... "Activation of the Cdc42 Effector N-Wasp by the Shigella flexneri Icsa Protein Promotes Actin Nucleation by Arp2/3 Complex and ...
2004). "The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization". ... Sprouty-related, EVH1 domain-containing protein 2 is a protein that in humans is encoded by the SPRED2 gene. SPRED2 is a member ... GeneReviews/NIH/NCBI/UW entry on Legius syndrome SPRED1 Sprouty-related, EVH1 domain-containing protein 1 v t e (Articles with ... "Entrez Gene: SPRED2 sprouty-related, EVH1 domain containing 2". Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A " ...
Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape and motility. RhoC can activate formins ... It has been found to have a direct relationship to advanced tumor stage and metastasis, with increases in stage being related ... 1999). "Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase". Science. 285 (5429): 895-8. ... Here is a list of the ones found so far: IQGAP1 (IQ-domain GTP-ase Activating Protein): an effector of RhoC to enhance ...
Actin-related protein 2 is a protein that in humans is encoded by the ACTR2 gene. The specific function of ACTR2 has not yet ... "Entrez Gene: ACTR2 ARP2 actin-related protein 2 homolog (yeast)". Bearer EL, Prakash JM, Li Z (2002). "Actin dynamics in ... "The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches ... 1998). "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of ...
"The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches ... Actin-related protein 3 is a protein that in humans is encoded by the ACTR3 gene. The specific function of this gene has not ... "Entrez Gene: ACTR3 ARP3 actin-related protein 3 homolog (yeast)". Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, ... Machesky LM, Insall RH (1999). "Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton ...
The actin formation required to close the wounds in young chicks is controlled by Rho GTPase proteins, since, after injection ... Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R (1989). "Rac, a novel ras-related family of proteins that are botulinum ... A second target to explain the role of the Rho proteins in cancer is their regulatory proteins. Rho proteins are very tightly ... GDI proteins form a large complex with the Rho protein, helping to prevent diffusion within the membrane and into the cytosol ...
"The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins". ... Myopodin contains a novel actin binding site (between amino acids 410 and 563) in the center of the protein. During myotube ... Myopodin protein, also called Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene. Myopodin is expressed ... "Cardiac Organellar Protein Atlas Knowledgebase (COPaKB) -- Protein Information". heartproteome.org. "SYNPO2 - Synaptopodin-2 - ...
... binding protein Calcium-binding protein 1 S100 calcium-binding protein A1 TATA-binding protein Actin-binding protein Most actin ... This article includes a list of related items that share the same name (or similar names). If an internal link incorrectly led ... DNA-binding protein Single-strand binding protein Telomere-binding protein RNA-binding protein Poly(A)-binding protein Nuclear ... binding protein Syntaxin binding protein 2 Oxysterol-binding protein E3 binding protein Iron-responsive element-binding protein ...
Machesky, L. M.; Insall, R. H. (1998). "Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin ... Insall is a frequent commentator on issues related to science policy, reproducibility, and science publishing. He was chosen by ... With Laura Machesky, he identified an important signaling pathway that controls the behavior of the actin cytoskeleton. Insall ... 14 (3): e1002404. doi:10.1371/journal.pbio.1002404. ISSN 1545-7885. PMC 4794234. PMID 26981861. Insall, Robert (2011). "Career ...
Machesky LM, Insall RH (1998). "Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton ... The WH2 domain binds to actin monomers and can facilitate the assembly of actin monomers into actin filaments. Human genes ... Protein families, Membrane proteins, All stub articles, Membrane protein stubs). ... It is found in WASP proteins which control actin polymerisation, therefore, WH2 is important in cellular processes such as cell ...
Machesky LM, Insall RH (March 1999). "Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin ... Bear JE, Rawls JF, Saxe CL (1998). "SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late ... Miki H, Suetsugu S, Takenawa T (February 1999). "WAVE, a novel WASP-family protein involved in actin reorganization induced by ... Marchand JB, Kaiser DA, Pollard TD, Higgs HN (2001). "Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 ...
Actin-binding LIM protein 3 is a protein that in humans is encoded by the ABLIM3 gene. The LIM domain is a double zinc finger ... Diseases associated with ABLIM3 include hepatoblastoma, and among its related super-pathways are axon guidance and DCC mediated ... "Entrez Gene: ABLIM3 actin binding LIM protein family, member 3". Krupp M, Weinmann A, Galle PR, Teufel A (Jan 2006). "Actin ... Krupp M, Weinmann A, Galle PR, Teufel A (Jan 2006). "Actin binding LIM protein 3 (abLIM3)". International Journal of Molecular ...
Coronin, actin binding protein, 1B also known as CORO1B is a protein which in humans is encoded by the CORO1B gene. Members of ... Studies related to this protein are as follows: Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches ... Okumura M, Kung C, Wong S, Rodgers M, Thomas ML (September 1998). "Definition of family of coronin-related proteins conserved ... "Entrez Gene: CORO1B coronin, actin binding protein, 1B". Cai L, Makhov AM, Schafer DA, Bear JE (September 2008). "Coronin 1B ...
Actin-related protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene. This gene encodes one of ... "Entrez Gene: ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa". Welch MD, Iwamatsu A, Mitchison TJ (1997). "Actin ... "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily ... Marchand JB, Kaiser DA, Pollard TD, Higgs HN (2001). "Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 ...
Actin-related protein 2/3 complex subunit 4 is a protein that in humans is encoded by the ARPC4 gene. This gene encodes one of ... "Entrez Gene: ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa". "Dysmorphology data for Arpc4". Wellcome Trust Sanger ... "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ...
"Alternative splicing products of the gene for a human nuclear actin-related protein, hArpNbeta/Baf53, that encode a protein ... Actin-like protein 6A is a protein that in humans is encoded by the ACTL6A gene. This gene encodes a family member of actin- ... related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have ... Kuroda Y, Oma Y, Nishimori K, Ohta T, Harata M (November 2002). "Brain-specific expression of the nuclear actin-related protein ...
Actin-related protein 2/3 complex subunit 5 is a protein that in humans is encoded by the ARPC5 gene. This gene encodes one of ... "Entrez Gene: ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa". Millard TH, Behrendt B, Launay S, Fütterer K, Machesky ... "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ...
Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. This gene encodes one ... "Entrez Gene: ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa". Abella, Jasmine V. G.; Galloni, Chiara; Pernier, ... Overview of all the structural information available in the PDB for UniProt: Q58CQ2 (Bovine Actin-related protein 2/3 complex ... "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily ...
Zhang Y, Chen K, Tu Y, Wu C (2004). "Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins ... Members of the parvin family, including PARVA, PARVB and PARVG, are actin-binding proteins associated with focal contacts.[ ... Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ...