Acridine
... is easily oxidized by peroxymonosulfuric acid to the acridine amine oxide. The carbon 9-position of acridine is ... biologically active acridines, applications of acridines, new syntheses and reactions of acridines] Wikisource has original ... Acridine and its homologues are weakly basic. Acridine is a photobase which has a ground state pKa of 5.1, similar to that of ... Acridine and related derivatives (such as amsacrine) bind to DNA and RNA due to their abilities to intercalate. Acridine orange ...
Acridine yellow
... damages DNA and is used as a mutagen in microbiology. Acridine yellow is similar to acridine orange. According ... Acridine yellow, also known as acridine yellow G, acridine yellow H107, basic yellow K, and 3,6-diamino-2,7-dimethylacridine, ... It is a derivate of acridine. In histology, it is used as a fluorescent stain, and as a fluorescent probe for non-invasive ... Acridine yellow absorption and emission spectra v t e (Articles needing additional references from July 2021, All articles ...
Acridine orange
... is derived from the organic molecule acridine, which was first discovered by Carl Grabe and Heinrich Caro, who ... Acridine orange and fluorescein have a maximum excitation at 502nm and 525 nm (green). When acridine orange associates with RNA ... Acridine orange is useful in the rapid screening of ordinarily sterile specimens. When acridine orange is used with flow ... Acridine dyes are prepared via the condensation of 1,3-diaminobenzene with suitable benzaldehydes. Acridine orange is derived ...
Acridine carboxamide
... is a chemotherapy agent that is being studied in the treatment of cancer. It belongs to the family of ... Ondansetron, an isomer of Acridine carboxamide Dittrich C, Dieras V, Kerbrat P, Punt C, Sorio R, Caponigro F, et al. (August ... Acridines, All stub articles, Antineoplastic and immunomodulating drug stubs). ...
DNA
Ferguson LR, Denny WA (September 1991). "The genetic toxicology of acridines". Mutation Research. 258 (2): 123-60. doi:10.1016/ ... Most intercalators are aromatic and planar molecules; examples include ethidium bromide, acridines, daunomycin, and doxorubicin ...
August Bernthsen
Bernthsen, August (1884). "Die Acridine". Justus Liebig's Annalen der Chemie (in German). 224 (1-2): 1-56. doi:10.1002/jlac. ... Synthese der Acridine". Berichte der Deutschen Chemischen Gesellschaft (in German). 16 (2): 1802-1819. doi:10.1002/cber. ...
Graham Cairns-Smith
Cairns Smith, A. G. (1957). "Studies in the acridine series". {{cite journal}}: Cite journal requires ,journal= (help) Dennett ...
Acriflavine
It is derived from acridine. Commercial preparations are often mixtures with proflavine. It is known by a variety of commercial ...
Proflavine
Gatasheh MK, Kannan S, Hemalatha K, Imrana N (December 2017). "Proflavine an acridine DNA intercalating agent and strong ... Denny WA (September 2002). "Acridine derivatives as chemotherapeutic agents". Current Medicinal Chemistry. 9 (18): 1655-1665. ... Acridines, DNA intercalaters, All stub articles, Molecular and cellular biology stubs). ...
Chlorophyllin
... also binds to acridine orange. Chlorophyllin has been validated to exhibit ameliorative effects against food ...
Phenanthridine
It is an isomer of acridine. Phenanthridine was discovered by Amé Pictet and H. J. Ankersmit in 1891 by pyrolysis of the ...
Base pair
Leonard Lerman
Lerman, L. S. (1963). "The structure of the DNA-acridine complex". Proc. Natl. Acad. Sci. USA. 49 (1): 94-102. Bibcode:1963PNAS ... Lerman, L. S. (1961). "Structural considerations in the interactions of deoxyribonucleic acid and acridines". Journal of ...
Intercalation (biochemistry)
Lerman, L. S. (1963). "The structure of the DNA-acridine complex". Proceedings of the National Academy of Sciences of the ... 9 epoxide of aflatoxin B1 and acridines such as proflavine or quinacrine. Intercalation as a mechanism of interaction between ... "Structural considerations in the interaction of DNA and acridines" (PDF). Journal of Molecular Biology. 3 (1): 18-30. doi: ...
Arene substitution pattern
It is observed in compounds such as calixarenes and acridines. Peri-substitution occurs in naphthalenes for substituents at the ...
Decarboxylative cross-coupling
Derivatives are formed in moderate to good yield; acridine is essential for high reaction efficiency. Jiao et al. enabled the ...
Carl Hamilton Browning
He discovered the therapeutic qualities of acridine dyes. He was born on 21 May 1881 the son of Friederike Sophia Pauline (née ...
Fluorophore
Acridine derivatives: proflavin, acridine orange, acridine yellow, etc. Arylmethine derivatives: auramine, crystal violet, ...
Twisted intercalating nucleic acid
"Synthesis of Twisted Intercalating Nucleic Acids Possessing Acridine Derivatives. Thermal Stability Studies". Bioconjugate ...
Metachromasia
Darzynkiewicz Z, Kapuscinski J. (1990)"Acridine Orange, a Versatile Probe of Nucleic Acids and Other Cell Constituents." ... Another example of metachromatic dye (fluorochrome) is acridine orange. Under certain conditions it stains single-stranded ...
Benzaldehyde
... is also a precursor to certain acridine dyes. Via aldol condensations, benzaldehyde is converted into derivatives ...
Vital stain
Hathaway WE, Newby LA, Githens JH (1964). "The Acridine Orange Viability Test Applied to Bone Marrow Cells. I. Correlation with ...
Adelheid Kofler
Polymorphism of organic substances: acridine, catechol, diphenylamine and suberic acid) -- (1943). "Mikro-Thermoanalyse ...
Polymorphism (materials science)
Acridine has been obtained as eight polymorphs and aripiprazole has nine. The record for the largest number of well- ... Acridine Solid Form Landscape: Eight Polymorphs and a Hydrate" (PDF). Crystal Growth & Design. 19 (8): 4884-4893. doi:10.1021/ ...
Eva Hevia
"Zincate-Mediated Arylation Reactions of Acridine: Pre- and Postarylation Structural Insights" (PDF). Organometallics. 34 (11): ...
Oleocanthal
Cell apoptosis is tested by treating the lysosomal membrane with acridine orange. Acridine orange radiates a red fluorescent ...
Lysosome
Traganos F, Darzynkiewicz Z (1994). "Lysosomal proton pump activity: supravital cell staining with acridine orange ...
Sidney Altman
His project was a study of the effects of acridines on the replication of bacteriophage T4 DNA. He received his Ph.D. in ...
Boranylium ions
Clark, Ewan R.; Ingleson, Michael J. (2013-11-25). "[(acridine)BCl2]+: A Borenium Cation That Is a Strong Boron- and Carbon- ...
Cardiolipin
M Garciafernandez; D Ceccarelli; U Muscatello (2004). "Use of the fluorescent dye 10-N-nonyl acridine orange in quantitative ... Jacobson J, Duchen MR, Heales SJ (2002). "Intracellular distribution of the fluorescent dye nonyl acridine orange responds to ... Keij JF, Bell-Prince C, Steinkamp JA (2000). "Staining of mitochondrial membranes with 10-nonyl acridine orange, MitoFluor ... Based on this special structure, the fluorescent mitochondrial indicator, nonyl acridine orange (NAO) was introduced in 1982, ...