"Entrez Gene: RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)". Simicek M, Lievens S, ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... Ras-related protein Ral-B (RalB) is a protein that in humans is encoded by the RALB gene on chromosome 2. This protein is one ... Hsieh CL, Swaroop A, Francke U (1990). "Chromosomal localization and cDNA sequence of human ralB, a GTP binding protein". Somat ...

"Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... Wang KL, Roufogalis BD (May 1999). "Ca2+/calmodulin stimulates GTP binding to the ras-related protein ral-A". The Journal of ...

"The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. 21 ( ... Yu Y, Feig LA (2002). "Involvement of R-Ras and Ral GTPases in estrogen-independent proliferation of breast cancer cells". ... "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. 21 ( ... Ras-related protein R-Ras is a protein that in humans is encoded by the RRAS gene. RRAS has been shown to interact with: ARAF, ...

In turn, the intermediate protein stimulates GDP-bound Ras to the activated GTP-bound Ras. GAP eventually returns Ras to its ... and Ral pathway. Each pathway leads to the activation of transcription factors which enter the nucleus to alter gene expression ... Wnt proteins binds to its transmembrane receptor of the Frizzled family of proteins. The binding of Wnt to a Frizzled protein ... The BMPs bind to the bone morphogenetic protein receptor type II (BMPR2). Some of the proteins of the BMP family are BMP4 and ...

Ral-dependent branching implicated the phosphorylation of growth-associated protein GAP-43. Finally, Ral mutants unable to bind ... In 1993, Alan Hall was awarded the Feldberg Foundation Prize for his work on the role GTP-binding proteins played on signal ... In parallel with this experiment, Hall showed that the presence of Rac, another Ras-related GTP-binding protein, is implicated ... Ridley, Anne; Hall, Alan (7 August 1992). "The small GTP-binding protein rho regulates the assembly of focal adhesions and ...

A typical G-protein is active when bound to GTP and inactive when bound to GDP (i.e. when the GTP is hydrolyzed to GDP). The ... Ral, Rit, Rap, Rheb, and Rad. Miro is a recent contributor to the superfamily.[citation needed] Each subfamily shares the ... GTP-binding protein regulators Wennerberg K, Rossman KL, Der CJ (March 2005). "The Ras superfamily at a glance". J. Cell Sci. ... Therefore, a G-protein can be switched on and off. GTP hydrolysis is accelerated by GTPase activating proteins (GAPs), while ...

... ral gtp-binding proteins MeSH D08.811.277.040.330.300.400.462 - ran gtp-binding protein MeSH D08.811.277.040.330.300.400.475 - ... gtp-binding protein alpha subunits MeSH D08.811.277.040.330.300.200.100.100 - gtp-binding protein alpha subunits, g12-g13 MeSH ... gtp-binding protein alpha subunits, gi-go MeSH D08.811.277.040.330.300.200.100.200.500 - gtp-binding protein alpha subunit, gi2 ... gtp-binding protein alpha subunits, gq-g11 MeSH D08.811.277.040.330.300.200.100.400 - gtp-binding protein alpha subunits, gs ...

... rab2 gtp-binding protein MeSH D12.776.476.525.400.100 - rab3 gtp-binding proteins MeSH D12.776.476.525.400.100.100 - rab3a gtp- ... proto-oncogene proteins c-vav MeSH D12.776.476.325.300.600 - ral guanine nucleotide exchange factor MeSH D12.776.476.325. ... rac gtp-binding proteins MeSH D12.776.476.525.700.100.100 - rac1 gtp-binding protein MeSH D12.776.476.525.700.200 - rhoa gtp- ... rab4 gtp-binding proteins MeSH D12.776.476.525.400.200 - rab5 gtp-binding proteins MeSH D12.776.476.525.475.100 - rap1 gtp- ...

... is a cyclic AMP binding protein. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP- ... Spaargaren M, Bischoff JR (December 1994). "Identification of the guanine nucleotide dissociation stimulator for Ral as a ... 1999). "nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding ... such as RAPGEF2 serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key ...

... and Rho family monomeric GTP-binding proteins and protein kinase C-alpha". The Journal of Biological Chemistry. 272 (6): 3860-8 ... Suzuki J, Yamazaki Y, Li G, Kaziro Y, Koide H, Guang L (July 2000). "Involvement of Ras and Ral in chemotactic migration of ... There are two splice variants of the protein, PLD1a and PLD1b, but they do not seem to localize any differently. Alzheimer's ... Type II Diabetes: the protein PED/PEA15 is often elevated in type II diabetic patients, thus enhancing PLD1 activity, and in ...

... ral gtp-binding proteins MeSH D12.776.157.325.515.462 - ran gtp-binding protein MeSH D12.776.157.325.515.475 - rap gtp-binding ... gtp-binding protein alpha subunits, g12-g13 MeSH D12.776.157.325.332.100.200 - gtp-binding protein alpha subunits, gi-go MeSH ... gtp-binding protein alpha subunit, gi2 MeSH D12.776.157.325.332.100.300 - gtp-binding protein alpha subunits, gq-g11 MeSH ... gtp-binding protein alpha subunits, gs MeSH D12.776.157.325.332.520 - gtp-binding protein beta subunits MeSH D12.776.157.325. ...

... ral gtp-binding proteins MeSH D12.644.360.525.462 - ran gtp-binding protein MeSH D12.644.360.525.475 - rap gtp-binding proteins ... rab2 gtp-binding protein MeSH D12.644.360.525.400.100 - rab3 gtp-binding proteins MeSH D12.644.360.525.400.100.100 - rab3a gtp- ... rho gtp-binding proteins MeSH D12.644.360.525.700.050 - cdc42 gtp-binding protein MeSH D12.644.360.525.700.050.500 - cdc42 gtp- ... rac gtp-binding proteins MeSH D12.644.360.525.700.100.100 - rac1 gtp-binding protein MeSH D12.644.360.525.700.200 - rhoa gtp- ...

"Exocyst complex subunit sec8 binds to postsynaptic density protein-95 (PSD-95): a novel interaction regulated by cypin ( ... Brymora A, Valova VA, Larsen MR, Roufogalis BD, Robinson PJ (2001). "The brain exocyst complex interacts with RalA in a GTP- ... Polzin A, Shipitsin M, Goi T, Feig LA, Turner TJ (2002). "Ral-GTPase influences the regulation of the readily releasable pool ... The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting ...

... to a molecule of GTP. The K-Ras protein is turned off (inactivated) when it converts the GTP to GDP. When the protein is bound ... Spaargaren M, Bischoff JR (December 1994). "Identification of the guanine nucleotide dissociation stimulator for Ral as a ... Other than where GTP/GDP binds, there are no obvious high affinity binding sites for small molecules. One fairly frequent ... One potential drug interaction site is where GTP/GDP binds, but due to the extraordinarily high affinity of GTP/GDP for this ...