Mannosylglycoprotein endo-beta-mannosidase
... (EC 3.2.1.152, endo-beta-mannosidase) is an enzyme. This enzyme catalyses the ... Mannosylglycoprotein+endo-beta-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ... Ishimizu T, Sasaki A, Okutani S, Maeda M, Yamagishi M, Hase S (September 2004). "Endo-beta-mannosidase, a plant enzyme acting ... "Partial purification and characterization of a novel endo-beta-mannosidase acting on N-linked sugar chains from Lilium ...
Β-Mannosidase
1998). "Human beta-mannosidase cDNA characterization and first identification of a mutation associated with human beta- ... Overview of all the structural information available in the PDB for UniProt: Q8K2I4 (Mouse Beta-mannosidase) at the PDBe-KB. ... β-Mannosidase (EC 3.2.1.25}, mannanase, mannase, β-D-mannosidase, β-mannoside mannohydrolase, exo-β-D-mannanase, lysosomal β A ... 2009). "A MANBA mutation resulting in residual beta-mannosidase activity associated with severe leukoencephalopathy: a possible ...
Glycoside hydrolase family 1
6-phospho-beta-glucosidase (EC 3.2.1.86); lactase-phlorizin hydrolase (EC 3.2.1.62), lactase (EC 3.2.1.108); beta-mannosidase ( ... beta-galactosidase (EC 3.2.1.23); 6-phospho-beta-galactosidase (EC 3.2.1.85); ... Glycoside hydrolase family 1 CAZY GH_1 comprises enzymes with a number of known activities; beta-glucosidase (EC 3.2.1.21); ... EC 3.2.1.25); myrosinase (EC 3.2.1.147). 6-phospho-beta-galactosidase InterPro: IPR005928 GBA3; KL; KLB; LCT; LCTL; GH1 in ...
Glycoside hydrolase family 2
... beta-mannosidase (EC 3.2.1.25); beta-glucuronidase (EC 3.2.1.31). These enzymes contain a conserved glutamic acid residue which ... The catalytic domain of Beta-galactosidases have a TIM barrel core surrounded several other largely beta domains. The sugar ... Gebler JC, Aebersold R, Withers SG (June 1992). "Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta- ... These enzymes also include an immunoglobulin-like beta-sandwich domain. GH2 in CAZypedia Henrissat B, Callebaut I, Fabrega S, ...
Beta-mannosidosis
... , also called lysosomal beta-mannosidase deficiency, is a disorder of oligosaccharide metabolism caused by ... Beta-mannosidase "Mannosidosis, beta A, lysosomal , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". ... "OMIM Entry - * 609489 - MANNOSIDASE, BETA A, LYSOSOMAL; MANBA". www.omim.org. Retrieved 9 May 2018. Johnson, William (2015). ... The pathophysiology of this condition is better comprehended if one first looks at the normal function of beta-mannosidase, ...
Mannosidase
... is an enzyme which hydrolyses mannose. There are two types: alpha-Mannosidase beta-Mannosidase A deficiency is ... Mannosidases at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology v t e (EC 3.2.1, All stub ... A family of mannosidases are also responsible for processing newly formed glycoproteins in the endoplasmic reticulum into ...
Glycoside hydrolase family 26
4-beta-mannosidases. Mannan endo-1,4-beta-mannosidase hydrolyses mannan and galactomannan, but displays little activity towards ... Braithwaite KL, Black GW, Hazlewood GP, Ali BR, Gilbert HJ (February 1995). "A non-modular endo-beta-1,4-mannanase from ... The enzyme randomly hydrolyses 1,4-beta-D-linkages in mannans, galacto-mannans, glucomannans and galactoglucomannans. Henrissat ...
Mannan endo-1,4-β-mannosidase
Mannan+endo-1,4-beta-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC ... Mannan endo-1,4-β-mannosidase (EC 3.2.1.78, endo-1,4-β-mannanase, endo-β-1,4-mannase, β-mannanase B, β-1, 4-mannan 4- ...
Manba
... may refer to: Beta-mannosidase, an enzyme A branch of the alternative fashion trend Ganguro This disambiguation page ...
Arthrobacter alkaliphilus
... and beta-glucuronidase, alpha-glucosidase, alpha-mannosidase, pyrazinamidase, pyrrolidonyl arylamidase, and urease. This ...
Katalin Susztak
In follow-up animal model studies her laboratory conclusively demonstrated that the lysosomal beta-mannosidase, the adaptor ...
List of diseases (L)
... reductase deficiency Lysinuric protein intolerance Lysosomal alpha-D-mannosidase deficiency Lysosomal beta-mannosidase ...
Mannosidosis
... is a deficiency in mannosidase, an enzyme. There are two types: Alpha-mannosidosis and Beta-mannosidosis. ...
Paucimannosylation
From these two subunits, isoenzymes such as Hex A (one alpha and one beta subunit), Hex B (two beta subunits) and Hex S (two ... Moreover, α1,3-fucosyltransferase (FUT11/12) and β1,2-xylosyltransferase as well as α-mannosidase II were also reported to play ... Human Hex isoenzymes are assembled with alpha and beta subunits encoded by the HEXA and HEXB genes, respectively. ... and alpha-mannosidases, through GnT-I-dependent and -independent truncation pathways. Studies on insect cell lines and in vivo ...
List of MeSH codes (D08)
... mannosidases MeSH D08.811.277.450.625.500 - alpha-mannosidase MeSH D08.811.277.450.625.750 - beta-mannosidase MeSH D08.811. ... 4-beta-glucosidase MeSH D08.811.277.450.420.200.600 - glucan endo-1,3-beta-d-glucosidase MeSH D08.811.277.450.420.375 - glucan ... 4-beta-cellobiosidase MeSH D08.811.277.450.420.200.450 - endo-1,3(4)-beta-glucanase MeSH D08.811.277.450.420.200.500 - glucan 1 ... 4-beta xylanases MeSH D08.811.277.450.950.500 - xylan endo-1,3-beta-xylosidase MeSH D08.811.277.656.149 - atp-dependent ...
Pseudogymnoascus destructans
... alpha/beta-galactosidase, β-glucuronidase, α-fucosidase, α-mannosidase, and trypsin. Important dual virulence factors found in ...
List of MeSH codes (C18)
... mannosidase deficiency diseases MeSH C18.452.648.202.607.500 - alpha-mannosidosis MeSH C18.452.648.202.607.750 - beta- ... mannosidase deficiency diseases MeSH C18.452.648.595.577.500 - alpha-mannosidosis MeSH C18.452.648.595.577.750 - beta- ...
List of MeSH codes (C16)
... mannosidase deficiency diseases MeSH C16.320.565.202.607.500 - alpha-mannosidosis MeSH C16.320.565.202.607.750 - beta- ... mannosidase deficiency diseases MeSH C16.320.565.580.577.500 - alpha-mannosidosis MeSH C16.320.565.580.577.750 - beta- ... beta-thalassemia MeSH C16.320.077.090 - anemia, Diamond-Blackfan MeSH C16.320.077.280 - fanconi anemia MeSH C16.320.099.037 - ... beta-thalassemia MeSH C16.320.400.024 - Alexander disease MeSH C16.320.400.050 - amyloid neuropathies, familial MeSH C16.320. ...
Harry Schachter
Processing of asparagine-linked oligosaccharides by one or more rat liver Golgi alpha-D-mannosidases dependent on the prior ... action of UDP-N-acetylglucosamine: alpha-D-mannoside beta 2-N-acetylglucosaminyltransferase I". J Biol Chem. 255 (10): 4894-902 ...
Chromosome 20
Beta-catenin-like protein 1 DBNDD2: Dysbindin domain-containing protein 2 DDX27: DEAD box polypeptide 27 DEFB118, DEFB119, ... ER degradation-enhancing alpha-mannosidase-like 2 EDN3: endothelin 3 ENTPD6: Ectonucleoside triphosphate diphosphohydrolase 6 ... DEFB126, DEFB127, DEFB129: Beta-defensin genes DLGAP4: Disks large-associated protein 4 DNAJC5: Cysteine string protein EDEM2: ... encoding protein Beta-soluble NSF attachment protein NDUFAF5: encoding protein NADH:ubiquinone oxidoreductase complex assembly ...
Chromosome 5
... encoding protein Amyloid beta A4 precursor protein-binding family B member 3 APC: adenomatosis polyposis coli ARL15: encoding ... Alpha-mannosidase 2 MASS1: monogenic, audiogenic seizure susceptibility 1 homolog (mouse) MCC: Colorectal mutant cancer protein ... beta polypeptide) HMGXB3: encoding protein HMG-box containing 3 IK: Protein Red IRX1: Iroquois-class homeodomain protein (human ... glycoprotein beta-1,2-N-acetylglucosaminyltransferase MINAR2: encoding protein Kiaa1024 like MIR1271: encoding MicroRNA 1271 ...
Β-Galactosidase
A new isoform for beta-galactosidase with optimum activity at pH 6.0 (Senescence Associated beta-gal or SA-beta-gal) which is ... A few are evolved β-galactosidase (EBG), β-glucosidase, 6-phospho-β-galactosidase, β-mannosidase, and lactase-phlorizin ... Beta-Galactosidase activity can be overexpressed, and this can lead to various diseases afflicting a wide range of body systems ... Beta-gal is inhibited by L-ribose and by competitive inhibitors 2-phenylethyl 1-thio-β-D-galactopyranoside (PETG), D- ...
Ei mechanism
Evidence for an alpha', beta Mechanism". J. Am. Chem. Soc. 94 8608-. Reich, H. J., Peake, S. L. (1978). "Hypervalent ... Inhibitors of B-Mannosidases?". Helv. Chim. Acta. 85 1118-. Cope, A.C.; Mehta, A.S. (1963). "Mechanism of the Hofmann ...
List of skin conditions
B-mannosidase deficiency Carotenosis Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ... broad beta disease, remnant removal disease) Familial hypertriglyceridemia Farber disease (fibrocytic dysmucopolysaccharidosis ...
Inulinase
It forms a beta sandwich module. The crystal structures are shown here on either side of the page. The two structures of endo- ... glucosidases and mannosidases". J. Am. Chem. Soc. 65 (7): 1369-1380. doi:10.1021/ja01247a029. Liu Y, Zhou SH, Cheng YR, Chi Z, ... Being made of beta sheets allows the structures to be more stable during chemical reactions. Both of the inulinases have ... Inulinase contains a N-terminal domain of glycosyl hydrolase family 32 which forms a five bladed beta propeller structure and C ...
Glycoside hydrolase
One of the important occurrences of glycoside hydrolases in bacteria is the enzyme beta-galactosidase (LacZ), which is involved ... trimming mannosidases involved in N-linked glycoprotein biosynthesis). Together with glycosyltransferases, glycosidases form ...
Chromosome 6
... beta polypeptide (maple syrup urine disease) (6q14.1) BMIQ3: body mass index QTL 3 TMEM242 encoding transmembrane protein ... mannosidase alpha class 1A member 1 (6q22.31) MB21D1: encoding protein Mab-21 domain containing 1 MCDR1: macular dystrophy, ... N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (6p24.3) GGNBP1: encoding protein Gametogenetin binding protein ... encoding protein Dishevelled binding antagonist of beta catenin 2 DFNB38: deafness, autosomal recessive 38 DYX4: dyslexia ...
Chromosome 1
... beta; acid (includes glucosylceramidase) (gene for Gaucher disease) GBAP1: glucosylceramidase beta pseudogene 1 GLC1A: gene for ... 2-alpha-mannosidase IB MAP3K6: encoding protein Mitogen-activated protein kinase kinase kinase 6 MEAF6: MYST/ESA1 associated ... beta 3, 31kDa (connexin 31) GLMN (1p22) GNL2: G protein nucleolar 2 GSTM1 (1p13) GUCA2B: encoding protein Guanylate cyclase ... beta TTC39A: Tetratricopeptide repeat 39A UBR4: E3 ubiquitin-protein ligase component n-recognin 4 UROD: uroporphyrinogen ...
Mannose
Each ring closure can have either an alpha or beta configuration at the anomeric position. The chemical rapidly undergoes ... Glucose is hydrolyzed on fully folded protein and the mannose moieties are hydrolyzed by ER and Golgi-resident mannosidases. ... α-Mannosidase Mannose receptor Mannan oligosaccharide-based nutritional supplements Rhamnose, 6-deoxy-L-mannose PTS Mannose- ...
Jamey Marth
Gu, H.; Marth, J. D.; Orban, P. C.; Mossmann, H.; Rajewsky, K. (1994-07-01). "Deletion of a DNA polymerase beta gene segment in ... "Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis ... Ohtsubo, K.; Chen, M. Z.; Olefsky, J.M.; Marth, J.D. (2011). "Pathway to diabetes through attenuation of pancreatic beta cell ... Their research demonstrated that acquired pancreatic beta cell dysfunction was the major contributor of disease onset and ...