Voltage-dependent anion channels, or mitochondrial porins, are a class of porin ion channel located on the outer mitochondrial ... "Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel". Proc. Natl. Acad. Sci. U.S.A ... Voltage-Dependent+Anion+Channels at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article ... De Pinto, V.; Messina, A.; Lane, D. J. R.; Lawen, A. (2010). "Voltage-dependent anion-selective channel (VDAC) in the plasma ...

Voltage-dependent anion-selective channel protein 3 (VDAC3) is a protein that in humans is encoded by the VDAC3 gene on ... "Entrez Gene: voltage-dependent anion channel 3". Lee MJ, Kim JY, Suk K, Park JH (May 2004). "Identification of the hypoxia- ... De Pinto V, Messina A, Lane DJ, Lawen A (May 2010). "Voltage-dependent anion-selective channel (VDAC) in the plasma membrane". ... Hinsch KD, De Pinto V, Aires VA, Schneider X, Messina A, Hinsch E (Apr 2004). "Voltage-dependent anion-selective channels VDAC2 ...

"Affixing N-terminal α-helix to the wall of the voltage-dependent anion channel does not prevent its voltage gating". The ... "Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel". Proceedings of the National ... Voltage-dependent anion-selective channel 1 (VDAC-1) is a beta barrel protein that in humans is encoded by the VDAC1 gene ... "Entrez Gene: VDAC1 voltage-dependent anion channel 1". Reina S, Palermo V, Guarnera A, Guarino F, Messina A, Mazzoni C, De ...

Chandra D, Choy G, Daniel PT, Tang DG (May 2005). "Bax-dependent regulation of Bak by voltage-dependent anion channel 2". The ... Voltage-dependent anion-selective channel protein 2 is a protein that in humans is encoded by the VDAC2 gene on chromosome 10. ... Li Z, Wang Y, Xue Y, Li X, Cao H, Zheng SJ (Feb 2012). "Critical role for voltage-dependent anion channel 2 in infectious ... Alvira CM, Umesh A, Husted C, Ying L, Hou Y, Lyu SC, Nowak J, Cornfield DN (Nov 2012). "Voltage-dependent anion channel-2 ...

"Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death". Nature Cell Biology. 9 (5): 550-5. ... Hassouna A, Matata BM, Galiñanes M (Nov 2004). "PKC-epsilon is upstream and PKC-alpha is downstream of mitoKATP channels in the ... Li H, Yang T, Long Z, Cheng J (17 June 2014). "Effect of mitochondrial ATP-sensitive potassium channel opening on the ... Liedtke CM, Yun CH, Kyle N, Wang D (Jun 2002). "Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane ...

"Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death". Nature Cell Biology. 9 (5): 550-555. ... Initial experiments by Szabó and Zoratti proposed the MPT may comprise Voltage Dependent Anion Channel (VDAC) molecules. ... MPT induction is also due to the dissipation of the difference in voltage across the inner mitochondrial membrane (known as ... I. Binary structure and voltage dependence of the pore". FEBS Letters. 330 (2): 201-205. doi:10.1016/0014-5793(93)80273-w. PMID ...

The voltage-dependent anion channel of the mitochondrion is also upregulated. Infection with WSSV differs from other described ...

VDAC (voltage-dependent anion ion channel) is important for the exchange of small hydrophilic ions and metabolites with the ... Mertins B, Psakis G, Essen LO (December 2014). "Voltage-dependent anion channels: the wizard of the mitochondrial outer ... VDAC operation is voltage-dependent in which it closes at high voltage and can partially open towards slightly reduced anion ... Tom40 is the protein-conducting channel of the complex with beta-barrel structure, which forms a cation-selective channel. ...

June 2007). "RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels". Nature. 447 (7146): 864-8 ... Erastin binds and activates voltage-dependent anion channels (VDAC) by reversing tubulin's inhibition on VDAC2 and VDAC3, and ... May 2012). "Ferroptosis: an iron-dependent form of nonapoptotic cell death". Cell. 149 (5): 1060-72. doi:10.1016/j.cell.2012.03 ...

A major trafficking protein is the pore-forming voltage-dependent anion channel (VDAC). The VDAC is the primary transporter of ... Hoogenboom BW, Suda K, Engel A, Fotiadis D (July 2007). "The supramolecular assemblies of voltage-dependent anion channels in ... This type of cellular respiration, known as aerobic respiration, is dependent on the presence of oxygen. When oxygen is limited ... The process is mediated by a proton channel called thermogenin, or UCP1. Thermogenin is primarily found in brown adipose tissue ...

Arbel, Nir; Shoshan-Barmatz, Varda (2010-02-26). "Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to ... mitochondrial membrane of the animal cell where they are thought to form a complex with the voltage-dependent anion channel ... Kinnally KW, Antonsson B (May 2007). "A tale of two mitochondrial channels, MAC and PTP, in apoptosis". Apoptosis. 12 (5): 857- ... Martinez-Caballero S, Dejean LM, Jonas EA, Kinnally KW (June 2005). "The role of the mitochondrial apoptosis induced channel ...

... houses a voltage-dependent anion channel called the VDAC. This site is important for converting energy signals into electro- ... Tunneling is largely dependent upon the shape and size of a potential barrier, relative to the incoming energy of a particle. ... Because the incoming particle can be defined by a wave equation, its tunneling probability is dependent upon the potential ... Wiltschko, Roswitha; Ahmad, Margaret; Nießner, Christine; Gehring, Dennis; Wiltschko, Wolfgang (May 2016). "Light-dependent ...

It relies on inhibiting the voltage-dependent anion channel 2 (VDCA2) located on the mitochondria. The inhibition will be aided ... Viral protein 1 is an RNA-dependent RNA polymerase, which cycles between the two segments and aids in the formation of ... by VP2, which will close the channel allowing for proliferation of the virus in host cells. Also, VDCA2 will bind to RACK1 that ...

2002). "Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim". Oncogene. 21 (32 ...

They are associated with the major outer membrane porins (in prokaryotes) and with the voltage-dependent anion channel (in ... PBR forms a multimeric complex with the voltage-dependent anion channel (VDAC) and adenine nucleotide carrier. Molecular ... association with the voltage-dependent anion channel and the adenine nucleotide carrier". Proc. Natl. Acad. Sci. U.S.A. 89 (8 ... modeling of PBR suggested that it might function as a channel for cholesterol. Indeed, cholesterol uptake and transport by ...

Arzoine L, Zilberberg N, Ben-Romano R, Shoshan-Barmatz V (Feb 2009). "Voltage-dependent anion channel 1-based peptides interact ... Foster LJ, Rudich A, Talior I, Patel N, Huang X, Furtado LM, Bilan PJ, Mann M, Klip A (Jan 2006). "Insulin-dependent ... A study on non-insulin-dependent diabetes mellitus (NIDDM) revealed low basal G6P levels in NIDDM patients that failed to ... Specifically, HK2 binds VDAC to trigger opening of the channel and release mitochondrial ATP to further fuel the glycolytic ...

This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC ... BAX is believed to interact with, and induce the opening of the mitochondrial voltage-dependent anion channel, VDAC. ... "Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway". ...

Bax is believed to interact with, and induce the opening of the mitochondrial voltage-dependent anion channel, VDAC. ... Paroni G, Henderson C, Schneider C, Brancolini C (2001). "Caspase-2-induced apoptosis is dependent on caspase-9, but its ... "Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during ... processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3". J. Biol. Chem. 276 (24): 21907-15. doi ...

Schwarzer C, Barnikol-Watanabe S, Thinnes FP, Hilschmann N (2002). "Voltage-dependent anion-selective channel (VDAC) interacts ... Implication in dynein-dependent vesicle transport". J. Biol. Chem. 273 (46): 30065-8. doi:10.1074/jbc.273.46.30065. PMID ... 2004). "Receptor (CD155)-dependent endocytosis of poliovirus and retrograde axonal transport of the endosome". J. Virol. 78 (13 ... Strovel ET, Wu D, Sussman DJ (2000). "Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent ...

Schwarzer C, Barnikol-Watanabe S, Thinnes FP, Hilschmann N (2002). "Voltage-dependent anion-selective channel (VDAC) interacts ... "Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74 ... Bauch A, Campbell KS, Reth M (1998). "Interaction of the CD5 cytoplasmic domain with the Ca2+/calmodulin-dependent kinase ...

... the voltage-dependent anion channel". The Journal of Biological Chemistry. 268 (3): 1835-1841. doi:10.1016/S0021-9258(18)53930- ... January 1993). "Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, ... which is the ATP-dependent phosphorylation of glucose to G6P. Physiological levels of G6P can regulate this process by ...

... and have been shown to regulate outer mitochondrial membrane channel (voltage-dependent anion channels (VDACs) opening. VDACs ... "BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial ... "Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway". ... "Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation". Proceedings of the National Academy of ...

Crompton M, Virji S, Ward JM (Dec 1998). "Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and ...

It has been shown that BNIP3 interacts with the voltage-dependent anion channel (VDAC) to directly induce mitochondrial release ... EndoG-dependent pathways". Cellular Signalling. 19 (4): 705-14. doi:10.1016/j.cellsig.2006.08.019. PMID 17107772. Varecha M, ... "The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF ...

It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in ... Moreover, BAK1 is believed to induce the opening of the mitochondrial voltage-dependent anion channel, leading to release of ... and do not directly modulate voltage-dependent anion channel activity". Proceedings of the National Academy of Sciences of the ... "Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC". Nature. 399 (6735): ...

This interaction is important for rapid uptake of calcium by mitochondria through Voltage dependent anion channels (VDACs), ... RNA-dependent protein kinase (PKR)-like ER kinase), PERK contributes to apoptosis twofold by sustaining the levels of pro- ...

The PTP is composed of the voltage-dependent anion channel (VDAC), the inner membrane protein adenine nucleotide translocator ( ... "Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease ... "Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells". Blood. 98 (2): 414- ...

Proteins by in Silico Optimization of the Coding Sequence-An Experimental Study of the Human Voltage-Dependent Anion Channel". ...

... or voltage dependent anion channel. This association confers hexokinase direct access to ATP generated by mitochondria, which ...

Hedrich R, Busch H, & Raschke K (1990) Ca2+ and nucleotide dependent regulation of voltage dependent anion channels in the ... Keller BU, Hedrich R, & Raschke K (1989) Voltage-dependent anion channels in the plasma membrane of guard cells. Nature 341:450 ... Anion channels were identified as important controllers of stomatal closing. Anion channels have several major functions in ... At least two major types of anion channels have been characterized in the plasma membrane: S-type anion channels and R-type ...