... (rVSV vaccines) are vaccines made using recombinant Indiana vesiculovirus. rVSV ... This disambiguation page lists articles associated with the title Recombinant vesicular stomatitis virus vaccines. If an ... a candidate against the Marburg virus (development discontinued for business reasons) rVSV-based vaccine candidate against ...

"Role of the vesicular stomatitis virus matrix protein in maintaining the viral nucleocapsid in the condensed form found in ... Brown has worked widely on vesicular stomatitis virus, herpes simplex virus, and human papilloma virus. His research justified ... Newcomb, W W; Tobin, G J; McGowan, J J; Brown, J C (March 9, 1982). "In vitro reassembly of vesicular stomatitis virus ... the view that the vesicular stomatitis virus matrix M (VSV-M) protein plays a vital role in the maintenance of nucleocapsid in ...

For example, polysomal profiling was used in a study to investigate the effect of vesicular stomatitis virus (VSV) in mammalian ... Neidermyer WJ, Whelan SP (June 2019). "Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells ... Polysomes are present in archaea, but not much is known about the structure. in situ (in cell) studies have shown that ... with 3-D polyribosomes being found in sarcoma cells using fluorescence microscopy. Atomic force microscopy used in in vitro ...

The prototypical and best studied rhabdovirus is vesicular stomatitis Indiana virus. It is a preferred model system to study ... In 2015 two novel rhabdoviruses, Ekpoma virus 1 and Ekpoma virus 2, were discovered in samples of blood from two healthy women ... Ekpoma virus 1 and Ekpoma virus 2 appear to replicate well in humans (viral load ranged from ~45,000 - ~4.5 million RNA copies/ ... Exposure to Ekpoma virus 2 appears to be widespread in certain parts of Nigeria where seroprevalence rates are close to 50%. In ...

"Vesicular Stomatitis Virus, Indiana Serotype - Multiplication in and Transmission by Experimentally Infected Phlebotomine ... One such virus of medical importance is the vesicular stomatitis virus (VSV) of the genus Vesiculovirus. Viruses of this genus ... The disease is in endemic in 22 countries of tropical and subtropical America, where it is generally considered a zoonosis. ... Research has begun in an attempt to resolve evolutionary relationships between species in the genus, using molecular methods to ...

His research focused on the vesicular stomatitis virus. Wagner died of cancer in 2001. Wagner attended Columbia College as an ... Much of his research focused on the molecular biology of the vesicular stomatitis virus. With student Alice S. Huang, Wagner ... The journal launched in 1966, and Wagner continued in his role for 15 years, overseeing a large expansion in the size of the ... He served from 1947 to 1949, and became a lieutenant in the navy reserves. After his time in the Navy, Wagner moved to England ...

... particles of vesicular stomatitis virus in electron micrographs and the formalization of DIPs terminology was in 1970 by Huang ... Snapback defections have been observed in vesicular stomatitis virus. Panhandle defections are when the polymerase carries a ... Hackett AJ (September 1964). "A possible morphologic basis for the autointerference phenomenon in vesicular stomatitis virus". ... Mosaic or complex DI genome, in which the various regions may come from the same helper virus genome but in the wrong order; ...

BHK-21 cells are susceptible to human adenovirus D, reovirus 3, and vesicular stomatitis virus (Indiana strain). BHK-21 cells ... Baby Hamster Kidney fibroblasts (BHK cells) are an adherent cell line used in molecular biology. The cells were derived in 1961 ... Lim KI, Lang T, Lam V, Yin J (September 2006). "Model-based design of growth-attenuated viruses". PLOS Computational Biology. 2 ... "Robust kinetics of an RNA virus: Transcription rates are set by genome levels". Biotechnology and Bioengineering. 112 (8): 1655 ...

Indiana vesiculovirus, formerly Vesicular stomatitis Indiana virus (VSIV or VSV) is a virus in the family Rhabdoviridae; the ... Davis NL, Wertz GW (March 1982). "Synthesis of vesicular stomatitis virus negative-strand RNA in vitro: dependence on viral ... A human case of encephalitis associated with vesicular stomatitis virus (Indiana serotype) infection. Am J Trop Med Hyg. 1988; ... "Systemic vesicular stomatitis virus selectively destroys multifocal glioma and metastatic carcinoma in brain". The Journal of ...

"Role of temperature-sensitive mutants in persistent infections initiated with vesicular stomatitis virus". Journal of Virology ... and also infections of vesicular stomatitis virus, sendai virus, and persistent newcastle disease virus. Youngner is ... Youngner, J. S.; Quagliana, D. O. (1976-07-01). "Temperature-sensitive mutants of vesicular stomatitis virus are conditionally ... Youngner studied the role of in-apparent infections in an effort to link a selection of wild type virus to chronic and ...

Barik S, Banerjee AK (1991). "Cloning and expression of the vesicular stomatitis virus phosphoprotein gene in Escherichia coli ... Two forms of this protein have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the ... 2005). "Concentration of thymidine kinase 1 in serum (S-TK1) is a more sensitive proliferation marker in human solid tumors ... Munch-Petersen B (2005). "Differences in the kinetic properties of thymidine kinase isoenzymes in unstimulated and ...

It is well known as a vector of the vesicular stomatitis virus, which causes the disease vesicular stomatitis in animals, ... Emergence and re-emergence of vesicular stomatitis in the United States. Virus Research 85(2), 211-19. Vesicular Stomatitis. ... The bite of the female fly transmits the vesicular stomatitis virus in mammals. The disease in cattle and pigs is impossible to ... One well-studied vesicular stomatitis virus enzootic involving this fly is on Ossabaw Island off the coast of Georgia in the ...

... in 1976; his thesis research focused on vesicular stomatitis virus (VSV) under the supervision of Dr. David Baltimore and Dr. ... "Maturation of viral proteins in cells infected with temperature-sensitive mutants of vesicular stomatitis virus". Journal of ... "Separate pathways of maturation of the major structural proteins of vesicular stomatitis virus". Journal of Virology. 21 (3): ... "Analysis of the defects of temperature-sensitive mutants of vesicular stomatitis virus: intracellular degradation of specific ...

... expresses the surface glycoprotein of the Kikwit 1995 strain of Zaire ebolavirus in a recombinant vesicular stomatitis virus ... In the eight previous Ebola outbreaks in DRC since 1976, the virus had never before reached a major city. In May 2018, for the ... Health authorities including DRC's Ministry of Public Health used recombinant vesicular stomatitis virus-Zaire Ebola virus ( ... 2017). "A Recombinant Vesicular Stomatitis Virus Ebola Vaccine". New England Journal of Medicine. 376 (4): 330-41. doi:10.1056/ ...

"Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human ... She has been involved in research uncovering critical mechanisms in the pathogenesis of hemorrhagic fever viruses, and has used ... Hensley joined USAMRIID in 1998 as a research associate in the Pathology Division. She has co-authored over 180 publications in ... Hensley is the subject of a chapter in journalist Richard Preston's 2002 book Demon in the Freezer, which covers the history of ...

... recombinant vesicular stomatitis Indiana virus (VSIV) expressing the glycoprotein of MARV has been used successfully in ... Lassa Virus, Crimean-Congo Hemorrhagic Fever Virus, Rift Valley Fever Virus, Dengue Virus, and Yellow Fever Virus by Real-Time ... vesicular stomatitis Indiana virus (VSIV) or filovirus-like particles (VLPs) as all of these candidates could protect nonhuman ... MVD is caused by two viruses; Marburg virus (MARV) and Ravn virus (RAVV), family Filoviridae. Marburgviruses are endemic in ...

... of the processing intermediates in the synthesis of the complex oligosaccharide units of the vesicular stomatitis virus G ... The SNFG nomenclature has also been adopted as a standard by major databases and journals in the Biomedical Sciences. In 1978, ... Ensure uniform usage of the nomenclature in the literature, thus helping to ensure scientific accuracy in journal and online ... For long-term development of this symbol nomenclature and standardization of glycan representation in the Glycosciences, in ...

"Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in ... Also plays an important role in energy balance regulation by sustaining a state of chronic, low-grade inflammation in obesity, ... In addition, is also required for the induction of a subset of ISGs which displays antiviral activity, may be through the ... In order to establish such an antiviral state, IKBKE forms several different complexes whose composition depends on the type of ...

rVSV-ZEBOV is a live, attenuated recombinant vesicular stomatitis virus (VSV) in which the gene for the native envelope ... Newlink in turn licensed it to Merck in 2014. It was used in the DR Congo in a 2018 outbreak in Équateur province, and has ... Recombinant vesicular stomatitis virus-Zaire Ebola virus (rVSV-ZEBOV), also known as Ebola Zaire vaccine live and sold under ... Marzi A, Ebihara H, Callison J, Groseth A, Williams KJ, Geisbert TW, Feldmann H (November 2011). "Vesicular stomatitis virus- ...

... can refer to: Vesicular stomatitis virus, a virus in the family Rhabdoviridae Vishista Seva Vibhushanaya, a military ...

"Membrane deformations induced by the matrix protein of vesicular stomatitis virus in a minimal system". J Gen Virol. 86 (Pt 12 ... Kopecky SA, Lyles DS (May 2003). "The cell-rounding activity of the vesicular stomatitis virus matrix protein is due to the ... The family of vesiculovirus matrix proteins consists of several matrix proteins of the vesicular stomatitis virus, also known ... Gaudier, Martin; Gaudin, Yves; Knossow, Marcel (2002-06-17). "Crystal structure of vesicular stomatitis virus matrix protein". ...

Vesicular stomatitis virus (VSV) was introduced as a vaccine vector in the late 1990s. In most VSV vaccine vectors, attenuation ... June 1998). "Vaccination with a recombinant vesicular stomatitis virus expressing an influenza virus hemagglutinin provides ... The incorporation of several viruses in vaccination schemes has been investigated since the vaccinia virus was created in 1984 ... Marzi A, Ebihara H, Callison J, Groseth A, Williams KJ, Geisbert TW, Feldmann H (November 2011). "Vesicular stomatitis virus- ...

... the addition of self-inactivating plasmids and creating a more universal tropism by pseudotyping a vesicular stomatitis virus ... Many such viruses have been the basis of research using viruses in gene therapy, but the lentivirus is unique in its ability to ... There are multiple steps involved in the infection and replication of a lentivirus in a host cell. In the first step the virus ... Because the virus has been adapted to lose most of its genome, the virus becomes safer and more effective in transplanting the ...

LDLR has been identified as the primary mode of entry for the Vesicular stomatitis virus in mice and humans. In addition, LDLR ... It was also reported that by association with lipoprotein in the blood, viruses such as hepatitis C virus, Flaviviridae viruses ... "LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus". Proceedings of the ... Synthesis of receptors in the cell is regulated by the level of free intracellular cholesterol; if it is in excess for the ...

An RNA polymerase in the virion." This paper went on to show that "the virions of vesicular stomatitis virus contain an enzyme ... "Ribonucleic Acid Synthesis of Vesicular Stomatitis Virus, II. An RNA Polymerase in the Virion*". Proceedings of the National ... Huang and Baltimore coauthored a paper with Martha Stampfer titled "Ribonucleic acid synthesis of vesicular stomatitis virus, ... They studied the inhibition of cellular RNA synthesis by nonreplicating vesicular stomatitis virus, known to infect horses, ...

"Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in ... A key interest in TBK1 is due to its role in innate immunity, especially in antiviral responses. TBK1 is redundant with IKK ϵ ... In contrast, binding to NAP1 and SINTBAD leads to localization in the cytoplasm and involvement in autophagy. Another adaptor ... TBK1 is involved in many signaling pathways and forms a node between them. For this reason, regulation of its involvement in ...

In the context of viral infection vesicular stomatitis virus (VSV) challenge of murine peritoneal macrophages was reported to ... In DNA viruses, miRNAs were experimentally verified, miRNAs in viruses are encoded by dsDNAs, examples of such viruses include ... These investigators found that forced expression of miR-155-5p in bone marrow cells resulted in a ~50% decrease in SPI1 (i.e. ... Viruses can exploit host miRNAs to the degree that they use host miRNAs to encode for viral clones for example: miR-K12-11 in ...

In collaboration with Alice S. Huang, Reiss's lab studied viral encephalitis, the pathogenesis of Vesicular Stomatitis Virus ( ... In addition to the department of biology, she has faculty appointments in neural science in NYU's Faculty of Arts and Science, ... in biology, 1972), Sarah Lawrence College (M.S. in human genetics, 1973). She earned a Ph.D. in microbiology from Mount Sinai ... Reiss was editor-in-chief of the journal Viral Immunology (2000-2006) and is currently editor-in-chief of the journal DNA and ...

Huang also moved to MIT to continue her research on vesicular stomatitis virus (VSV). They became a couple, and married in ... 2 articles by Luke Frankiw published in 2019 and 2020). In an autobiographical piece published in Annual Review Immunology in ... The infectious clone, DNA encoding the genome of a virus, is a standard tool used today in virology. In 1982, with a charitable ... He also continued to pursue fundamental questions in RNA viruses and in 1981, Baltimore and Vincent Racaniello, a post-doctoral ...

... protects against viruses such as encephalomyocarditis virus and vesicular stomatitis virus as well as the hepatitis B virus in ... The receptor is expressed largely in epithelial cells, specifically keratinocytes and melanocytes found in the epidermis. The ... In binding to the receptor, interferon lambdas inhibit cell growth and the cell begins to produce cellular receptors that can ... Cells such as those in the central nervous system, uterus, bone marrow, testis and skeletal muscle have low mRNA levels and do ...