Lymphangiogenesis: Lymphangiogenesis is the formation of lymphatic vessels from pre-existing lymphatic vessels in a method believed to be similar to angiogenesis (blood vessel development).LymphangionVascular endothelial growth factor (VEGF) IRES ALymph: Lymph is the fluid that circulates throughout the lymphatic system. The lymph is formed when the interstitial fluid (the fluid which lies in the interstices of all body tissues)Fluid Physiology: 2.Lymphovascular invasionLymphokine: Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signalling between its cells.Soluble fms-like tyrosine kinase-1Angiostasis: Angiostasis is the strict regulation by the body over creation of new blood vessels, which is the normal state (homeostasis) for adult humans. The opposite state of angiostasis is angiogenesis, or the state of generating new blood vessels, as happens after injury, and during tumor growth.Vasculogenesis: Vasculogenesis is the process of blood vessel formation occurring by a de novo production of endothelial cells.HU-336Platelet-derived growth factor: Platelet-derived growth factor (PDGF) is one of the numerous growth factors, or proteins that regulate cell growth and division. In particular, it plays a significant role in blood vessel formation (angiogenesis), the growth of blood vessels from already-existing blood vessel tissue.Related to receptor tyrosine kinase: The related to receptor tyrosine kinase (RYK) gene encodes the protein Ryk.Endothelial activation: Endothelial activation is a proinflammatory and procoagulant state of the endothelial cells lining the lumen of blood vessels. It is most characterized by an increase in interactions with white blood cells (leukocytes), and it is associated with the early states of atherosclerosis and sepsis, among others.Endothelial progenitor cell: Endothelial progenitor cell (or EPC) is a term that has been applied to multiple different cell types that play roles in the regeneration of the endothelial lining of blood vessels. Despite the history and controversy, the EPC in all its forms remains a promising target of regenerative medicine research.Mature messenger RNA: Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA, it consists exclusively of exons, with all introns removed.Hypoxia-inducible factor-asparagine dioxygenase: Hypoxia-inducible factor-asparagine dioxygenase (, HIF hydroxylase) is an enzyme with system name hypoxia-inducible factor-L-asparagine, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating). This enzyme catalyses the following chemical reactionDnaX: DnaX is the gene that codes for the τ and γ subunits of the DNA clamp loader of prokaryotes. The eukaryotic equivalent to the DNA clamp loader is Replication Factor C, which is encoded by RFC1, RFC2, RFC3, RFC4, and RFC5.Heparin-binding EGF-like growth factor: Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene.Nude mouse