Uramustine
... (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in ... Chemically it is a derivative of nitrogen mustard and uracil. Ghorani-Azam A, Balali-Mood M (2015). "Clinical pharmacology and ... Nitrogen mustards, Pyrimidinediones, Organochlorides, Uracil derivatives, Chloroethyl compounds, All stub articles, ... It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic ...
Alkylating antineoplastic agent
Uramustine or uracil mustard Melphalan Chlorambucil Ifosfamide Bendamustine Nitrosoureas Carmustine Lomustine Streptozocin ... Before their use in chemotherapy, alkylating agents were better known for their use as sulfur mustard, ("mustard gas") and ... A common myth holds that Goodman and Gilman were prompted to study nitrogen mustards as a potential treatment for cancer ... Goodman, Gilman, and others began studying nitrogen mustards at Yale in 1942, and, following the sometimes dramatic but highly ...
List of MeSH codes (D03)
... uracil mustard MeSH D03.383.742.715 - pyrithiamine MeSH D03.383.742.795 - thiamine MeSH D03.383.742.795.300 - fursultiamin MeSH ... uracil MeSH D03.383.742.698.875.237 - bromouracil MeSH D03.383.742.698.875.404 - fluorouracil MeSH D03.383.742.698.875.404.850 ... quinacrine mustard MeSH D03.494.046.250.900 - tacrine MeSH D03.494.148.249 - ellipticines MeSH D03.494.148.500 - ondansetron ...
List of drugs: U
Urabeth Uracil Mustard Capsules (Roberts) uramustine (INN) urapidil (INN) Urasal Ureaphil Urecholine uredepa (INN) uredofos ( ...
IARC group 2B
Trypan blue Uracil mustard Vanadium pentoxide Vinyl acetate 4-Vinylcyclohexene 4-Vinylcyclohexene diepoxide Zalcitabine ... acetamide Nitrogen mustard N-oxide Nitromethane 2-Nitropropane 4-Nitropyrene N-Nitrosodi-n-butylamine N-Nitrosodiethanolamine N ...
List of MeSH codes (D02)
... propylbenzilylcholine mustard MeSH D02.455.526.728.650.760 - quinacrine mustard MeSH D02.455.526.728.650.913 - uracil mustard ... mustard gas MeSH D02.455.526.728.650 - nitrogen mustard compounds MeSH D02.455.526.728.650.050 - aniline mustard MeSH D02.455. ... phosphoramide mustards MeSH D02.455.526.728.650.730.243 - cyclophosphamide MeSH D02.455.526.728.650.730.243.250 - ifosfamide ... propylbenzilylcholine mustard MeSH D02.092.877.883.333.780 - succinylcholine MeSH D02.092.877.883.333.800 - thiocholine MeSH ...
Mutagen
Deaminating agents, for example nitrous acid which can cause transition mutations by converting cytosine to uracil. Polycyclic ... Other alkylating agents include mustard gas and vinyl chloride. Aromatic amines and amides have been associated with ... Robson found that mustard gas can cause mutations in fruit flies. A large number of chemical mutagens have since been ... which can substitute for DNA bases during replication and cause transition mutations.some examples are 5 bromo uracil and 2 ...
Chemotherapy
Originally derived from mustard gas used in World War I, there are now many types of alkylating agents in use. They are so ... The nucleobases are divided into purines (guanine and adenine) and pyrimidines (cytosine, thymine and uracil). Anti-metabolites ... Mustard gas was used as a chemical warfare agent during World War I and was discovered to be a potent suppressor of ... Nitrogen mustards include mechlorethamine, cyclophosphamide, melphalan, chlorambucil, ifosfamide and busulfan. Nitrosoureas ...
Caffeine
Wright GA, Baker DD, Palmer MJ, Stabler D, Mustard JA, Power EF, Borland AM, Stevenson PC (March 2013). "Caffeine in floral ... Zajac MA, Zakrzewski AG, Kowal MG, Narayan S (2003). "A Novel Method of Caffeine Synthesis from Uracil" (PDF). Synthetic ...