Mesenchymal Stem/Stromal Cells Derived From Pluripotent Stem Cells", Mesenchymal Stromal Cells as Tumor Stromal Modulators, ... Stromal cells play a large role in the distinction of hematopoietic cells (cells that can differentiate into other blood cells ... Stromal cells, or mesenchymal stromal cells, are differentiating cells found in abundance within bone marrow but can also be ... tumor cells can convert these reactive stromal cells further and transition them into tumor-associated stromal cells (TASCs). ...

They include all non-T-lineage cells, such as thymic epithelial cells (TECs), endothelial cells, mesenchymal cells, dendritic ... The predominant stromal cells found in the postnatal thymus are thymic epithelial cells (TECs). cTECs - (cortical thymic ... Thymus stromal cells are subsets of specialized cells located in different areas of the thymus. ... The most serious clinical expression of a thymic stromal cell defect is profound T cell lymphopaenia, presenting as a complete ...

There are several stromal cell derived factors: Stromal cell-derived factor-1 (SDF-1, SDF1, Sdf1) Stromal cell-derived factor-1 ... Stromal cell-derived factor-2 (SDF-2, SDF2, Sdf2) Stromal cell-derived factor-3 (SDF-3, SDF3, Sdf3) Stromal cell-derived factor ... This disambiguation page lists articles associated with the title Stromal cell-derived factor. If an internal link led you here ...

... dendritic cells move to the T cell zone or to the B cell follicle along the fibroblast reticular cell network. Dendritic cells ... Most lymph node stromal cells preferentially express DF1, an Aire-like transcription modulator. Lymph node stromal cells can be ... Stromal cells originate from multipotent mesenchymal stem cells. Lymph nodes are enclosed in an external fibrous capsule, from ... Lymph node stromal cells can give rise to a number of malignancies including: follicular dendritic cell sarcoma; fibroblastic ...

It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small ... Zheng H, Fu G, Dai T, Huang H (2007). "Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha ... Stellos K, Gawaz M (March 2007). "Platelets and stromal cell-derived factor-1 in progenitor cell recruitment". Seminars in ... Neural progenitor cells (NPCs) are stem cells that differentiate into glial and neuronal cells. CXCL12 promotes their migration ...

An endometrial stromal nodule is a noninfiltrative, circumscribed proliferation of endometrial stromal cells and is a benign ... The appearance of the cells is identical to normal endometrial stromal cells. This can only be differentiated from low-grade ... Diagnosis may be aided by immunostaining; endometrial stromal nodules are positive for CD10; leiomyomas are positive for ... endometrial stromal sarcoma by confirming lack of infiltration. The differential includes cellular leiomyoma. ...

BAFF is secreted by a variety of cells: monocytes and macrophages; bone marrow stromal cells; astrocytes in certain ... When autoimmune B cells attack the body's own tissues, they are normally destroyed by cell suicide (apoptosis). Researchers ... Belimumab binds to BAFF and prevents it from binding to B cells. Without BAFF, B cells commit suicide and no longer contribute ... decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys". The ...

... epithelial cells and different types of stromal or stromal-like cells.[citation needed] TSLP production has been observed in ... stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells ... "Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human ... Ziegler SF, Liu YJ (July 2006). "Thymic stromal lymphopoietin in normal and pathogenic T cell development and function". Nature ...

Owen, M.; Friedenstein, A. J. (1988). "Stromal stem cells: marrow-derived osteogenic precursors". Ciba Foundation Symposium. ... and nucleated cells. The adult stem cell fraction is present in the nucleated cells of the marrow. Most of these cells are ... meaning they are cells that have the ability to develop into more than one type of specialized cell. Mesenchymal stem cells ... Mesenchymal stem cells (MSCs) are multipotent cells found in multiple human adult tissues, including bone marrow, synovial ...

Owen M; Friedenstein AJ (1988). "Stromal stem cells: marrow- derived osteogenic precursors". Ciba Found Symp. Novartis ... The rapidity with which premature cell death can occur depends on the cell type and the degree and duration of the anoxia. ... In healthy bone these cells are constantly replaced by differentiation of bone marrow mesenchymal stem cells (MSC). However, in ... bone cell damage and eventual cell death (apoptosis). Of significance is the fact that the average concentration of cadmium in ...

Stromal cell secretion of hepatocyte growth factor (HGF). At the maximum tolerated dose (MTD) of 960 mg twice a day 31% of ... Activates the ERK Pathway and Enhances Cell Migration and Proliferation of BRAF(WT) Melanoma Cells". Pigment Cell Melanoma Res ... Vemurafenib causes programmed cell death in melanoma cell lines. Vemurafenib interrupts the B-Raf/MEK step on the B-Raf/MEK/ERK ... "Hairy Cell Leukemia: Celebrating Progress?". HCLF Blog. July 29, 2022. Retrieved July 25, 2022. "Hairy Cell Leukemia with ...

Mesenchymal stem cells (MSCs) also known as mesenchymal stromal cells or medicinal signaling cells are multipotent stromal ... Stromal cells are connective tissue cells that form the supportive structure in which the functional cells of the tissue reside ... May 2012). "Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis". Cell Stem Cell ... fat cells which give rise to marrow adipose tissue). While the terms mesenchymal stem cell (MSC) and marrow stromal cell have ...

"Mesenchymal Stromal Cells as a Driver of Inflammaging". International Journal of Molecular Sciences. 24 (7): 6372. doi:10.3390/ ... IL-6 is pro-inflammatory in nature and can be produced by many cells of the immune system as well as non-immune cells, like ... The secretome of senescent mesenchymal stem and stromal cells (MSCs) exhibits immunomodulatory effects and serves as a driver ... Cells with the SASP are characterized by being in cell cycle arrest, releasing inflammatory factors, and possessing a ...

... is all widely expressed on stromal cells. The N-terminal fragment of GPR126 contains C1r-C1s, Uegf and Bmp1 (CUB), and ... Mogha A, Benesh AE, Patra C, Engel FB, Schöneberg T, Liebscher I, Monk KR (November 2013). "Gpr126 functions in Schwann cells ... Forced GPR126 expression in COS-7 cells enhances cAMP levels by coupling to heterotrimeric Gαs/i proteins. GPR126 has been ... Upon lipopolysaccharide (LPS) or thrombin stimulation, expression of GPR126 is induced by MAP kinases in endothelial cells. ...

J Cell Biol. 133 (2): 257-68. doi:10.1083/jcb.133.2.257. PMC 2120788. PMID 8609160. "Entrez Gene: SDF4 stromal cell derived ... Cell. 18 (7): 2473-80. doi:10.1091/mbc.E06-10-0950. PMC 1924827. PMID 17442889. v t e (Articles with short description, Short ... binding proteins localised to the secretory pathway of mammalian cells". FEBS Lett. 466 (1): 11-8. doi:10.1016/S0014-5793(99) ...

... (PASH) is an overgrowth of myofibroblastic cells in the breast. It has an appearance ... Powell CM, Cranor ML, Rosen PP (March 1995). "Pseudoangiomatous stromal hyperplasia (PASH). A mammary stromal tumor with ...

"Vasculogenic mimicry of acute leukemic bone marrow stromal cells". Leukemia. 23 (6): 1039-1048. doi:10.1038/leu.2009.10. PMID ... Vaudry, D.; Stork, PJ; Lazarovici, P; Eiden, LE (31 May 2002). "Signaling Pathways for PC12 Cell Differentiation: Making the ... in PC12 Cells". Journal of Molecular Neuroscience. 54 (3): 574-585. doi:10.1007/s12031-014-0388-2. PMID 25078264. S2CID 1620005 ... Endothelial Cell Tube Formation Assay". Neurotrophic Factors. Methods in Molecular Biology. Vol. 1727. pp. 239-250. doi:10.1007 ...

Eckel-Mahan K, Latre AR, Kolonin MG (2020). "Adipose Stromal Cell Expansion and Exhaustion: Mechanisms and Consequences". Cells ... PPARγ is necessary and sufficient to promote fat cell differentiation. PPARγ is required for embryonic stem cells (ES cells) ... Comparing with cells from other lineage, the in vitro differentiation of fat cells is authentic and recapitulates most of the ... Green H, Kehinde O (28 February 1974). "Sublines of mouse 3T3 cells that accumulate lipid". Cell. 1 (3): 113-116. doi:10.1016/ ...

The stem cell secretome (also referred to as the stromal cell secretome) is a collective term for the paracrine soluble factors ... stem cell factor (SCF), granulocyte colony-stimulating factor (G-CSF) and stromal cell-derived factor (SDF-1) both in vitro and ... "The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration". Cytotherapy. 18 (1 ... "Secretome of mesenchymal stem/stromal cells in regenerative medicine". Biochimie. Special section : The Mesenchymal Stem Cell ...

... epithelial and stromal cells in vaginal adenosis show characteristic fusion through the basal lamina or with stromal ... Roberts, Daniel K.; Walker, Nola J.; Parmley, Tim H.; Horbelt, Douglas V. (1988). "Interaction of epithelial and stromal cells ... Its mucinous cells resemble the normal cervical lining, while its tuboendometrial cells resemble the lining of normal fallopian ... Association with clear cell adenocarcinoma in diethylstilbestrol-exposed offspring". Cancer. 54 (5): 869-875. doi:10.1002/1097- ...

2001). "Human thymic stromal lymphopoietin preferentially stimulates myeloid cells". J. Immunol. 167 (1): 336-43. doi:10.4049/ ... 1996). "Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves ... Banham AH (2007). "Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells". Trends ... Akashi K, Kondo M, Weissman IL (1999). "Role of interleukin-7 in T-cell development from hematopoietic stem cells". Immunol. ...

... stroma of ovary stroma of thyroid gland stroma of thymus stroma of bone marrow lymph node stromal cell multipotent stromal cell ... immune system blood cells causing inflammatory response. Fixed cells - cells that are permanent inhabitants of the tissue. ... Stromal tissue falls into the "functional" class that contributes to the body's support and movement. The cells which make up ... Stromal tissue is primarily made of extracellular matrix containing connective tissue cells. Extracellular matrix is primarily ...

Cismasiu VB, Radu E, Popescu LM (May 2011). "miR-193 expression differentiates telocytes from other stromal cells". Journal of ... Stem Cells and Development. 21 (13): 2508-19. doi:10.1089/scd.2011.0695. PMC 3424971. PMID 22384930. ... "MicroRNA-193 pro-proliferation effects for bone mesenchymal stem cells after low-level laser irradiation treatment through ...

2001). "Human thymic stromal lymphopoietin preferentially stimulates myeloid cells". J. Immunol. 167 (1): 336-43. doi:10.4049/ ... 2007). "Cutting edge: direct action of thymic stromal lymphopoietin on activated human CD4+ T cells". J. Immunol. 178 (11): ... It forms a ternary signaling complex with TSLP and interleukin-7 receptor-α, capable of stimulating cell proliferation through ... 2002). "Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr ...

... is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The ... a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth". Proc Natl Acad Sci U S A. 91 (12): ... Bst1 (Bone marrow stromal cell antigen 1, ADP-ribosyl cyclase 2, CD157) is an enzyme that in humans is encoded by the BST1 gene ... "Entrez Gene: BST1 bone marrow stromal cell antigen 1". Quarona V, Zaccarello G, Chillemi A (2013). "CD38 and CD157: a long ...

"The Cell Surface Proteome of Human Mesenchymal Stromal Cells". PLOS ONE. 6 (5): e20399. Bibcode:2011PLoSO...620399N. doi: ... and role in mitochondrial function in cell life and death". Cell Biochem. Biophys. 39 (3): 279-92. doi:10.1385/CBB:39:3:279. ... "Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells". J. Cell Biol. 152 (2): 237 ... There is debate as to whether or not this channel is expressed in the cell surface membrane. This major protein of the outer ...

West-Mays JA, Dwivedi DJ (2006). "The keratocyte: corneal stromal cell with variable repair phenotypes". Int. J. Biochem. Cell ... "Interleukin-1alpha downregulates extracellular-superoxide dismutase in human corneal keratoconus stromal cells". Mol. Vis. 13: ... Cell Dev. Biol. 19 (2): 100-12. doi:10.1016/j.semcdb.2007.10.004. PMID 18077195. Lassen N, Pappa A, Black WJ, Jester JV, Day BJ ... List of human cell types derived from the germ layers Wilson SE, Chaurasia SS, Medeiros FW (September 2007). "Apoptosis in the ...

Low-grade endometrial stromal sarcoma consists of cells resembling normal proliferative phase endometrium, but with ... Endometrial stromal sarcoma is a malignant subtype of endometrial stromal tumor arising from the stroma (connective tissue) of ... Monotonous ovoid cells to spindly cells with minimal cytoplasm. Prominent arterioles. Angiolymphatic invasion common. Up to 10- ... 2009). "Gene fusion and RNA trans-splicing in normal and neoplastic cells". Cell Cycle. 8 (2): 218-222. doi:10.4161/cc.8.2.7358 ...

Kreins AY, Bonfanti P, Davies EG (2021). "Current and Future Therapeutic Approaches for Thymic Stromal Cell Defects". Frontiers ...

In physiological bone turn over, osteoblasts and stromal cells release RANKL, this acts on macrophages and monocytes which fuse ... Osteoprotegerin (OPG) is also secreted by osteoclasts and stromal cells; this inhibits RANKL and therefore osteoclast activity ... It is postulated that osteoclasts are the cells responsible for the resorption of the root surface. Osteoclasts can break down ... doi:10.1034/j.1601-1546.2002.10106.x. Andreasen JO (1981). "Relationship between cell damage in the periodontal ligament after ...