... as can vertebral spondylosis and ischemia. Multiple sclerosis is a disease that can damage the spinal cord, as can infectious ... A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function. Symptoms ... Anterior spinal artery syndrome also known as anterior spinal cord syndrome, due to damage to the front portion of the spinal ... At each level of the spinal column, spinal nerves branch off from either side of the spinal cord and exit between a pair of ...
It is possible that spinal cord ischaemia patients have a full recovery. Although the mortality rate after spinal cord ... Unlike anterior spinal cord stroke, motor functions are not handicapped in posterior spinal cord stroke. In central spinal cord ... thus reducing the risk of spinal cord ischaemia. Probability of postoperative spinal cord stroke is linked to both aneurysm ... Spinal cord stroke is a rare type of stroke with compromised blood flow to any region of spinal cord owing to occlusion or ...
... spinal cord, brain, and lung injury; injury due to ischemia in the heart, brain, kidney, and gut; and stress-induced central ... 14-PGJ2 appears to cause the dilation of coronary arteries and thereby protect against cardiac ischemia and heart attack in a ...
For instance, ischemia-reperfusion SCI involves the interruption of blood flow to the spinal cord. Complications have been ... The theory behind the new spinal cord stimulator is that in certain cases of spinal cord injury the spinal nerves between the ... Spinal cord injury research seeks new ways to cure or treat spinal cord injury in order to lessen the debilitating effects of ... Spinal cord implants, such as e-dura implants, designed for implantation on the surface of the spinal cord, are being studied ...
In the past, paraplegia caused by spinal cord ischemia due to erroneous embolization of the anterior spinal artery was well ... As described below, there are no reports on spinal cord ischemia in ssBACE, which is considered the most serious complication ... However, according to Ishikawa et al., spinal cord infarction still occurs, with an incidence of 0.19% (16/8563). They also ... Ishikawa, Hideo; Ohbe, Hiroyuki; Omachi, Naoki; Morita, Kojiro; Yasunaga, Hideo (2021-01-19). "Spinal Cord Infarction after ...
Lamin, S.; Bhattacharya, J. J. (2003-04-01). "Vascular Anatomy of the Spinal Cord and Cord Ischaemia". Practical Neurology. 3 ( ... and spans the length of the spinal cord. It supplies the grey and white posterior columns of the spinal cord. The posterior ... At the spinal cord level, the posterior spinal artery supplies the dorsal and lateral column as well as the peripheral part of ... Particularly at the upper cervical spinal cord where the posterior spinal artery supplies some parts of the ventral column, ...
Ubbink DT, Vermeulen H (April 2006). "Spinal cord stimulation for critical leg ischemia: a review of effectiveness and optimal ... Ubbink DT, Vermeulen H (February 2013). "Spinal cord stimulation for non-reconstructable chronic critical leg ischaemia". The ... Spinal cord stimulation is a form of invasive neuromodulation therapy in common use since the 1980s. Its principal use is as a ... All forms of spinal cord stimulation have been shown to have varying degrees of efficacy to address a variety of ...
... it can result in a syndrome of spinal cord ischemia, similar to anterior spinal artery syndrome, with loss of urinary and fecal ... "Prevention of spinal cord ischaemia during descending thoracic and thoracoabdominal aortic surgery". European Journal of Cardio ... and supplies the lower two-thirds of the spinal cord via the anterior spinal artery. The artery is named after Albert Wojciech ... In a study of approximately 70 people that examined the spinal cord's blood supply it was found that: The Adamkiewicz artery ...
This pathologic phenomenon can also occur after brain injury and spinal cord injury. Within minutes after spinal cord injury, ... Brain trauma or stroke can cause ischemia, in which blood flow is reduced to inadequate levels. Ischemia is followed by ... Hulsebosch CE, Hains BC, Crown ED, Carlton SM (April 2009). "Mechanisms of chronic central neuropathic pain after spinal cord ... Excitotoxicity may be involved in cancers, spinal cord injury, stroke, traumatic brain injury, hearing loss (through noise ...
It may present as stroke or spinal cord infarct. Signs and symptoms vary with vascular territory involved. The middle cerebral ... It is due to inflammation of the vasculature supplying the central nervous system, that results in ischemia. It typically ... Tabes dorsalis thought to be due to irreversible degeneration of nerve fibers in posterior columns of the spinal cord involving ... The extension of cellular immune response to the brainstem and spinal cord causes inflammation and necrosis of small meningeal ...
Indeed, its receptor is expressed by neurons in the brain and spinal cord. The action of G-CSF in the central nervous system is ... Due to its neuroprotective properties, G-CSF is currently under investigation for cerebral ischemia in a clinical phase IIb and ... "Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and ... are published for other neurological disease such as amyotrophic lateral sclerosis A combination of human G-CSF and cord blood ...
"MK-801 improves neurological and histological outcomes after spinal cord ischemia induced by transient aortic cross-clipping in ... "N-methyl-D-aspartate antagonist MK801 improves outcome following traumatic spinal cord injury in rats: behavioral, anatomic, ... When dizocilpine was administered to rats 15 minutes after a spinal trauma, the long-term neurological recovery of the trauma ... Gill R, Foster AC, Woodruff GN (October 1987). "Systemic administration of MK-801 protects against ischemia-induced hippocampal ...
Mechanisms of pain include spinal cord ischemia and traction on the periosteum, dura, nearby soft tissues, and nerve roots. ... 2. Spinal Cord Tumor Presentations Pain is the first symptom in >90% of patients presenting with epidural metastasis and occurs ... Neuro-oncology is the study of brain and spinal cord neoplasms, many of which are (at least eventually) very dangerous and life ... If other neurologic symptoms suggestive of myelopathy are present, without pain, the clinician should evaluate for spinal cord ...
Spinal Cord Ischaemia in Endovascular Thoracic and Thoraco-abdominal Aortic Repair: Review of Preventive Strategies". European ... "A systematic review and meta-analysis of the occurrence of spinal cord ischemia after endovascular repair of thoracoabdominal ... Spinal cord injury related to aortic repair occurs due to impaired blood flow to the spine after coverage of blood vessels, ... Spinal cord injury is a devastating complication after aortic surgery, specifically for thoracoabdominal aortic aneurysm repair ...
The neural signals are then transferred to the brainstem, followed by the spinal cord, which is the location where the heart ... This includes cardiac ischemia, stroke, epilepsy, and most importantly, heart arrhythmias and cardiac myopathies. Many of these ... the heart receives its neural input through parasympathetic and sympathetic ganglia and lateral grey column of the spinal cord ...
... the remaining α-MNs innervate the rest of the body and are found in the spinal cord. There are more α-MNs in the spinal cord ... Damage may be caused by trauma, ischemia, and infection, among others. In addition, certain diseases are associated with the ... is innervated by α-MNs in spinal cord segments C5, C6, and C7, which are found rostrally in the spinal cord. On the other hand ... which are found caudally in the spinal cord. Alpha motor neurons are located in a specific region of the spinal cord's gray ...
TIA is now defined as a transient episode of neurologic dysfunction caused by focal brain, spinal cord, or retinal ischemia, ... focal cerebral ischemia, cerebral infarction, and global cerebral ischemia. Prolonged hypoxia induces neuronal cell death via ... Problems during labor and delivery can include umbilical cord occlusion, torsion or prolapse, rupture of the placenta or uterus ...
Overall, ethyl pyruvate has been found to be beneficial in wound healing, liver disease, pancreatitis, and spinal cord repair. ... Relating to health, there are still many researchers using ethyl pyruvate in their projects pertaining to myocardial ischemia, ...
... are located in the lateral and ventral funiculi of the spinal cord. Since the ventral and dorsal spinal cord have separate ... They are effectively used to determine cortical ischemia during carotid endarterectomy surgeries and for mapping the sensory ... Examples of SEP usage include: SSEP can be used to locate lesions such as peripheral nerve or spinal cord. VEP and BAEP can ... In the peripheral nervous system pain and heat signals are carried along thin (C and A delta) fibers to the spinal cord, and ...
... leading to spinal cord ischemia. This is now widely accepted and has had major implications for the treatment of these lesions ... Aminoff MJ: Spinal Angiomas. Blackwells: Oxford, 1976 Gelb, DJ; Lowenstein, DH; Aminoff, MJ (1989). "Controlled trial of ... Logue, V; Aminoff, MJ; Kendall, BE (1974). "The results of surgical treatment for patients with a spinal angioma". Journal of ... Aminoff's clinical studies of spinal vascular malformations (dural arteriovenous fistulas) led to a new theory on their ...
... she published the effects of ziconotide in a rat model of spinal cord ischemia. In 2005, she published a series of papers on ... of intrathecal administration of the selective N-type calcium channel blocker ziconotide in a rat model of spinal ischemia". ...
... when SCS is applied in neuropathic pain states may be very different from that involved in analgesia due to limb ischemia. In ... There are also spinal cord stimulators under research and development that could enable patients with spinal cord injury to ... the spinal cord. In September 2018, Mayo Clinic and UCLA reported that spinal cord stimulation supported with physical therapy ... of lead migration for spinal cord stimulation. The neurophysiological mechanisms of action of spinal cord stimulation are not ...
Rates of postoperative spinal cord ischaemia can be kept at low levels after open surgical repair with the adequate precautions ...
... ischemia] of the brain and spinal cord". Spontaneous conversion of ventricular fibrillation to a more benign rhythm is rare in ... In conditions such as myocardial ischaemia, possible mechanism of arrhythmia generation include the resulting decreased ... abnormal cells can be exposed to an abnormal environment such as with a myocardial infarction with myocardial ischaemia. ...
... spinal cord ischemia and other neurological complications. With regards to rhythm disturbances, in particular atrial ... ischemia, sudden blockage of a coronary artery, a tear in the lining of an artery, kidney damage or stroke. Many of the risks ...
... ischemia, and anesthesia. TREK-1 has an important role in neuroprotection against epilepsy and brain and spinal cord ischemia ...
... spinal cord ischemia leading to paralysis, buttock claudication, ischemic colitis, embolization leading to acute limb ischemia ... reduces the risk of ischemic spinal cord injury by increasing the perfusion pressure to the spinal cord. A 2012 Cochrane ... Development of spinal cord injury is associated with increased perioperative mortality after the complex aortic repair. ... This can lead to inadequate blood supply to the spinal cord, resulting in paraplegia, when repairing thoracic aneurysms. A 2004 ...
... and ischemia may develop. The kidneys and the central nervous system (brain and spinal cord) are the parts of the body most ...
... spinal cord injury, diabetes, and many other areas. In addition, Stupp's laboratory is pursuing fundamental research on ... angiogenesis for ischemia or peripheral artery disease, cancer therapy, novel therapies for neurodegenerative diseases, stem ... "Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury". Science. 374 (6569): 848-856 ...
... ischemia, traumatic brain injury and spinal cord injury. Excessive amounts of calpain can be activated due to Ca2+ influx after ... As a few of the many examples supporting the therapeutic potential of calpain inhibition in ischemia, calpain inhibitor AK275 ... Neuhof C, Neuhof H (2014). "Calpain system and its involvement in myocardial ischemia and reperfusion injury". World J Cardiol ... and MDL28170 significantly reduced the size of damaged infarct tissue in a rat focal ischemia model. Also, calpain inhibitors ...