... (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene- ... "Analysis of the sex-determining region of the Y chromosome (SRY) in sex reversed patients: point-mutation in SRY causing sex- ... Sex-Determining+Region+Y+Protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) PDBe-KB provides an ... "A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif". Nature. 346 ( ...

SRY (sex determining region Y)-box 30 is a protein that in humans is encoded by the SOX30 gene. This gene encodes a member of ... The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may ... provided by RefSeq, Jul 2013]. "Entrez Gene: SRY (sex determining region Y)-box 30". Retrieved 2014-05-29. Koopman, P; Schepers ... Human proteins, All stub articles, Human chromosome 5 gene stubs). ...

"Entrez Gene: SOX15 SRY (sex determining region Y)-box 15". Wilson M, Koopman P (2003). "Matching SOX: partner proteins and co- ... The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. SOX genes ... Protein SOX-15 is a protein that in humans is encoded by the SOX15 gene. This gene encodes a member of the SOX (SRY-related HMG ... 1999). "Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11". ...

"Entrez Gene: SOX14 SRY (sex determining region Y)-box 14". Wilson M, Koopman P (August 2002). "Matching SOX: partner proteins ... The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in ... Transcription factor SOX-14 is a protein that in humans is encoded by the SOX14 gene. This intronless gene encodes a member of ...

SOX gene family Sex-Determining Region Y Protein SOX1, SOX2, etc. TCF/LEF family (T cell factor/lymphoid enhancer factor family ... HMG-box proteins are found in a variety of eukaryotic organisms. They were originally isolated from mammalian cells, and named ... Antibodies to HMG proteins are found in patients with autoimmune diseases. The SRY gene on the Y Chromosome, responsible for ... The HMG proteins are subdivided into 3 superfamilies each containing a characteristic functional domain: HMGA - contains an AT- ...

The sex-determining region of the human Y chromosome encodes a finger protein Genealogies of mouse inbred strains Mutations in ... Fisher, Elizabeth M. C. (1987). "The sex-determining region of the human Y chromosome encodes a finger protein". Cell. 51 (6): ... Her early work looked at the male sex determining factor and then considered the genes responsible for Turner syndrome. Fisher ... She has investigated how the RNA-binding protein mutant FUS behaves in mouse models. Fisher serves as a Council Member at the ...

"The sex-determining region of the human Y chromosome encodes a finger protein". Cell. 51 (6): 1091-104. doi:10.1016/0092-8674( ... Zinc finger Y-chromosomal protein is a protein that in humans is encoded by the ZFY gene of the Y chromosome. This gene encodes ... Agate RJ, Choe M, Arnold AP (February 2004). "Sex differences in structure and expression of the sex chromosome genes CHD1Z and ... In mice, Zfy genes are necessary for meiotic sex chromosome inactivation (MSCI). In Zfy knockout spermatocytes, sex chromosomes ...

"The sex-determining region of the human Y chromosome encodes a finger protein". Cell. 51 (6): 1091-1104. doi:10.1016/0092-8674( ... "A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif". Nature. 346 ( ... Despite a belief among geneticists that the Y chromosome contained few genes other than the sex-determining gene, Page ... Nature published his findings together with a paper from the British group that identified the sex-determining gene, which they ...

"Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets". Diabetes. 49 (4): 555 ... "Entrez Gene: SOX13 SRY (sex determining region Y)-box 13". Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, ... The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also ... SOX13+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ...

This gene encodes the testis-determining factor protein (also known as sex-determining region Y protein). Turner syndrome ... male sex-determining) Y chromosome. sSMC are, by definition, smaller in size than one of the smaller human chromosomes, ... This area, termed the PKS critical region, contains three genes, ING4, CHD4, and MFAP5 (also termed the MAGP2 gene), one or ... The exact genetic material in this sSMC that contributes to the development of the cited birth defects has not been determined ...

This gene encodes the testis-determining factor protein (also known as sex-determining region Y protein). Turner syndrome ... All regions of the world and cultures are affected about equally. Generally people with Turner syndrome have a shorter life ... Turner syndrome (TS), also known as 45,X, or 45,X0, is a genetic disorder caused by a sex chromosome monosomy, compared to the ... Ford CE, Jones KW, Polani PE, De Almeida JC, Briggs JH (April 1959). "A sex-chromosome anomaly in a case of gonadal dysgenesis ...

"A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif". Nature. 346 ( ... "A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed ... "How the Y Chromosome makes a male: Molecular genetic analysis of key sex-determining genes - UQ Researchers". researchers.uq. ... With a growing interest in human variations of sex development (alternatively known as DSD, differences or disorders of sex ...

19 July 1990). "A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif ... The genetic sex is determined by whether a Y bearing or next bearing sperm fertilizes the open; the presence or absence of a Y ... Female sex is determined by the absence of a Y chromosome. Some individuals are male who have the XX male syndrome and androgen ... Genetic sex determines whether the gonads will be testes or ovaries. In the developing embryo if the testes are developed, it ...

19 July 1990). "A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif ... Having a testis determines maleness, not having a testis determines femaleness. The ovary is not sex-determining. It will not ... the sex of an individual is determined by a pair of sex chromosomes. In most cases, females have two of the same kind of sex ... sex-determining region of the Y chromosome). Sexual differentiation (human) Secondary sex characteristic (human) Y-chromosomal ...

Fraser, JA, Heitman, J (September 2005). "Chromosomal sex-determining regions in animals, plants and fungi". Curr Opin Genet ... Hull, CM, Boily, MJ, Heitman, J (March 2005). "Sex-specific homeodomain proteins Sxi1alpha and Sxi2a coordinately regulate ... "Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms". PLOS Biology. 2 (12): e384. doi ... Wang, X, Hsueh, YP, Li, W, Floyd, A, Skalskey, R, Heitman J (November 2010). "Sex-induced silencing defends the genome of ...

The other testis-specific circRNA, sex-determining region Y (Sry), also was found as a miR-138 sponge. About-mentioned examples ... Li, JH; Liu, S; Zhou, H; Qu, LH; Yang, JH (Jan 1, 2014). "starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA ... circRNA has also been shown in viral infection where it sequesters anti-viral protein to enhance viral replication. This ...

The main targets in the cffDNA analysis are the gene responsible for the sex-determining region Y protein (SRY) on the Y ... sex-determining region Y gene (SRY) and Y chromosome short tandem repeat "DYS14" in cffDNA from 511 pregnancies were analyzed ... The use of nested polymerase chain reaction (nested PCR) was evaluated to determine sex by detecting a Y chromosome specific ... When assessing the technique, no false positives or negatives were found when looking for cffDNA to determine fetal sex in ...

Differentiation of the gonads begins after the 6th week, which is determined by the sex-determining region Y (SRY) gene in the ... These processes are initiated and regulated by biological metabolites such as DNA, hormones and proteins. The initial steps of ... Hence, examination (typically at birth) is carried out where the sex of the patient will be determined through imaging and ... "Disorders of Sex Development Loci☆". Disorders of Sex Development Loci. Elsevier. doi:10.1016/B978-0-12-809633-8.06552-3. ISBN ...

The Y sex-determining transcription factor works to regulate BZW2 expression in the testis. Throughout the body, BZW2 is ... There are four major stem loops in the 5' untranslated and four in the 3' untranslated region that function in transcript-level ... "Protein BLAST: search protein databases using a protein query". blast.ncbi.nlm.nih.gov. Retrieved 2020-07-31. Koonin EV (August ... The protein rep is part of SARS-CoV-2 virus and inhibits translation of BZW2. BZW2 has been studied to determine its role in ...

... also known as sex-determining region Y (SRY) protein that is found on the Y chromosome. He has founded two biotechnology ... "EXCERPT: 'How Sex Works'". ABC News. Miller, Jen A. "Review: 'How Sex Works: Why We Look, Smell, Taste, Feel, and Act the Way ... The SOX3 gene encodes a protein that is similar but distinct to the testis-determining factor (TDF), ... He is the author of the New York Times bestselling book Survival of the Sickest, as well as How Sex Works, Inheritance and The ...

... homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins ... "Entrez Gene: SOX12 SRY (sex determining region Y)-box 12". Hoser M, Potzner MR, Koch JM, Bösl MR, Wegner M, Sock E (August 2008 ... SOX12 is a protein that in humans is encoded by the SOX12 gene. Sox12 belongs to the SoxC group of Sox family of transcription ... The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various ...

... hmgb2 protein MeSH D12.776.660.235.400.600.800 - hmgb3 protein MeSH D12.776.660.235.400.700 - sex-determining region y protein ... hmga proteins MeSH D12.776.660.235.400.500.100 - hmga1a protein MeSH D12.776.660.235.400.500.200 - hmga1b protein MeSH D12.776. ... hmga2 protein MeSH D12.776.660.235.400.600 - hmgb proteins MeSH D12.776.660.235.400.600.300 - hmgb1 protein MeSH D12.776. ... MeSH D12.776.660.235.400.400 - hmgn proteins MeSH D12.776.660.235.400.400.200 - hmgn1 protein MeSH D12.776.660.235.400.400.300 ...

... sex-determining HMG box factors, and various homeobox/homeodomain binding sites. The TMEM247 gene codes for a single protein, ... Transmembrane protein 247 has two transmembrane domains. The three regions of the protein that remain are predicted to be ... Notable in the protein are two transmembrane regions near the c-terminus of the translated polypeptide. Transmembrane protein ... Protein kinases may modify transmembrane protein 247, and a variety of sites along the translated protein have been predicted ...

... screens Sall4 can also bind other important pluripotency proteins such as Nanog and sex determining region Y (SRY)-box 2 ... "The conserved glutamine-rich region of chick csal1 and csal3 mediates protein interactions with other spalt family members. ... metastasis-associated proteins (MTA), methyl-CpG-binding domain proteins (MBD2 or MBD3), and histone deacetylases (HDAC1 and ... protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells". The Journal ...

A gene in the sex-determining region of the short arm of the Y, now referred to as SRY, has been found to direct production of ... a protein, testis determining factor, which binds to DNA, inducing differentiation of cells derived from the genital ridges ... Pokorná, Martina; Kratochvíl, Lukáš (2009-05-01). "Phylogeny of sex-determining mechanisms in squamate reptiles: are sex ... Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage ...

... a gene found in the sex determining region of the Y chromosome of the hoverfly C. piger. DmX is located in region 5D5/6-E1 of ... The motif is likely responsible for protein-protein interactions. In most WD-repeat proteins the motif is repeated four to ... Rabconnectin-3A belongs to the superfamily of WD-repeat proteins which consists of mainly regulatory proteins involved in a ... as indicated by its non-sex-specific expression. DmX encodes for the relatively large protein rabconnectin-3A, which consists ...

IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the ... Jacobs, Patricia A.; Strong, John A. (January 31, 1959). "A case of human intersexuality having a possible XXY sex-determining ... In the wake of the establishment of the normal number of human chromosomes, 47,XYY was the last of the common sex chromosome ... 1982). Children with sex chromosome aneuploidy: follow-up studies. Birth defects original article series 18 (4). New York: Alan ...

The promoter region of TEX55 has multiple SRY box-6 and SOX/SRY-sex/testis determining and related HMG box transcription factor ... Through function-region analysis, researchers found that this protein may act as an anchoring protein of cAMP-dependent type-II ... This indicates that the sex chromosomes may play a role in post-translational modification and expression. The TEX55 protein ... Analysis done by the Human Protein Atlas indicates that the TEX55 protein can be found not only in the testis, but also the ...

... sex-determining region), ZFY (zinc finger protein), PRKY (protein kinase, Y-linked), AMELY (amelogenin, Y-linked), ANT3Y ( ... Although the Y-chromosome is sex-determining in humans and some other species, not all genes that play a role in sex ... In guppies, Y-linked genes help determine sex selection. This is done indirectly by traits that allow the guppy to appear more ... The Y-chromosome, generally does not undergo genetic recombination and only small regions called pseudoautosomal regions ...

... development of the male gonads is primarily controlled by the testis determining factor located on the sex-determining region ... StAR protein) which regulates steroid hormone production. 46,XY gonadal dysgenesis is characteristic of male hypogonadism with ... Bashamboo A, McElreavey K (2015). "Human sex-determination and disorders of sex-development (DSD)". Seminars in Cell & ... XY disorders of sex development (DSD) using a C57BL/6J-Y POS mouse model". Biology of Sex Differences. 9 (8): 8. doi:10.1186/ ...