... when taken daily can be useful for the treatment of premature ejaculation. A disadvantage of sertraline is that it ... For severe depression, sertraline is as good as clomipramine but is better tolerated. Sertraline appears to work better in ... Sertraline is subject to extensive first-pass metabolism, as indicated by a small study of radiolabeled sertraline in which ... The elimination half-life of sertraline is on average 26 hours, with a range of 13 to 45 hours. The half-life of sertraline is ...

A role of the σ1 site in the pharmacological action of sertraline may exist, but the significance of sertraline affinity for σ1 ... The compound was named sertraline (figure 8). Although sertraline appears to differ structurally from the other SSRIs, it has a ... Sertraline has about 60 times more potent inhibition potential on 5-HT than either NE or DA re-uptake. It is possible that only ... The bound sertraline molecule has its dichlorophenyl ring rotated about the C4-C13 bond by 180 degrees compared to the free ...

Sertraline • Sibutramine • Tametraline • Tripelennamine Deserpidine • Ibogaine • Reserpine • Tetrabenazine Morpholines: ...

"Sertraline Sandoz Tablet". NPS MedicineWise. Archived from the original on 9 January 2019. Retrieved 9 January 2019. "EU/3/09/ ...

Altshuler, L. L.; Pierre, J. M.; Wirshing, W. C.; Ames, D. (August 1994). "Sertraline and akathisia". Journal of Clinical ...

Sertraline in OCD. A twelve-week non-comparative study of the safety, efficacy and toleration of Sertraline in the treatment of ... Sertraline in OCD: A twelve week, non-comparative study of the safety, efficacy and toleration of Sertraline in the treatment ...

... paroxetine and sertraline. Paroxetine has slightly higher response and remission rates for PTSD than sertraline, but both are ... SSRIs such as sertraline have been found to be effective in decreasing anger. Side effects vary among the individual drugs of ... Only two SSRIs are licensed for use with children in the UK, sertraline (Zoloft) and fluvoxamine (Luvox), and only for the ... Fluvoxamine is an agonist of the σ1 receptor, while sertraline is an antagonist of the σ1 receptor, and paroxetine does not ...

B. Kenneth Koe, Charles A. Harbert, Reinhard Sarges, Albert Weissman, Willard M. Welch (2006). "Discovery of sertraline (Zoloft ... which in turn led to the discovery of the now widely popular antidepressant sertraline, a selective serotonin reuptake ...

Sertraline and fluvoxamine extended-release were later approved for it as well, while escitalopram is used off-label with ... Sertraline and fluoxetine are effective in treating OCD for children and adolescents. Clomipramine, a TCA drug, is considered ... Paroxetine and sertraline have been FDA approved for the treatment of PTSD. Paroxetine has slightly higher response and ... However, it did not address as many symptoms of PTSD as paroxetine and sertraline, in part due to the fact that venlafaxine is ...

"Sertraline prescribing information" (PDF). Archived (PDF) from the original on 16 June 2015. Retrieved 30 January 2015. " ... Commonly used SSRIs include sertraline, fluoxetine, fluvoxamine, paroxetine, citalopram, and escitalopram. Some patients fail ... Sertraline and fluoxetine are effective in treating OCD for children and adolescents. SSRIs help people with OCD by inhibiting ...

Desmethylsertraline - active metabolite of sertraline; 76 nM for SERT, 420 nM for NET, 440 nM for DAT 3,4-Dichlorotametraline ( ... trans-(1R,4S)-sertraline) (1980) Venlafaxine analogues, LPM580098 & LPM580153. And TP1 later reassigned name to PA01. PRC ( ...

"The Effects of Sertraline on Psychopathic Traits". International Clinical Psychopharmacology. 26 (6): 329-337. doi:10.1097/YIC. ...

... take SSRIs such as fluoxetine or sertraline. Adverse drug reactions associated with fluconazole therapy include: Common (≥1% of ...

Tametraline Sertraline Indatraline Koe BK (December 1976). "Molecular geometry of inhibitors of the uptake of catecholamines ...

Traditionally, antidepressants such as sertraline, fluoxetine, citalopram, nortriptyline and amitriptyline have been prescribed ... "Sertraline in stroke-associated lability of mood". International Journal of Geriatric Psychiatry. 14 (8): 681-5. doi:10.1002/( ...

Effective antidepressants are fluoxetine, sertraline, or paroxetine. Both fluoxetine and light therapy are 67% effective in ... "A placebo-controlled study of sertraline in the treatment of outpatients with seasonal affective disorder". Psychopharmacology ...

Sertraline has often been debated to have side effects that can trigger hypomania. These include antipsychotics such as: ... Mendhekar, D. N.; Gupta, D.; Girotra, V. (1 July 2003). "Sertraline‐induced hypomania: a genuine side‐effect". Department of ... Mendhekar, D. N.; Gupta, D.; Girotra, V. (13 June 2003). "Sertraline‐induced hypomania: a genuine side‐effect". Acta ...

JNJ-7925476 Lometraline Nefopam Sertraline Koe BK, Weissman A, Welch WM, Browne RG (September 1983). "Sertraline, 1S,4S-N- ... Sertraline has been called "3,4-dichloro-tametraline". This is correct but it is an oversimplification in the sense that ... is the parent of a series of chemical compounds investigated at Pfizer that eventually led to the development of sertraline (CP ... sertraline is the S,S-isomer whereas tametraline is the 1R,4S-stereoisomer. 1R-Methylamino-4S-phenyl-tetralin is a potent ...

Zoloft (sertraline) - an antidepressant of the SSRI class. Zulresso (brexanolone) - a GABA Modulator Antidepressants Zyprexa ( ...

Other commonly used treatments include rifampin, naloxone, and sertraline. In cholestatic liver disease, when bilirubin ...

Pfizer has denied that sertraline can cause such effects. Serotonin reuptake inhibitors (SSRI) have been associated with a ...

Romero-Martínez Á, Murciano-Martí S, Moya-Albiol L (May 2019). "Is Sertraline a Good Pharmacological Strategy to Control Anger ... These include selective serotonin reuptake inhibitor (SSRI) antidepressants like sertraline, certain anticonvulsant mood ...

Türkoğlu S (2015). "Serotonin syndrome with sertraline and methylphenidate in an adolescent". Clinical Neuropharmacology. 38 (2 ...

Türkoğlu S (2015). "Serotonin syndrome with sertraline and methylphenidate in an adolescent". Clinical Neuropharmacology. 38 (2 ...

Sertraline and amitriptyline inhibit butyrylcholinesterase and cause prolonged paralysis. Mivacurium causes prolonged paralysis ... for patients chronically taking sertraline. LAs may enhance the effects of depolarisation and nondepolarising NMBAs through pre ...

Sertraline, escitalopram, duloxetine might also help in reducing symptoms. Some antidepressants have not been shown to be ... and sertraline, have greater efficacy than placebo on achieving a 50% reduction in depression scores in moderate and severe ...

Sertraline, escitalopram, duloxetine might also help in reducing symptoms. Escitalopram and fluoxetine are among the safest ...

Gawad, M. and Osman, M. Effect and safety of Sertraline. The Egyptian Journal of Psychiatry 1991; 14:145-168. Ashoor, A., Osman ...

Compared to escitalopram and sertraline, indeed, fluvoxamine's gastrointestinal profile may be less intense, often being ... CYP2B6 (weakly) which metabolizes bupropion, cyclophosphamide, sertraline, tamoxifen, valproate, etc. By so doing, fluvoxamine ... sertraline, thioridazine, zuclopenthixol, etc. CYP2C9 (moderately) which metabolizes nonsteroidal anti-inflammatory drugs, ...

Evidence is not sufficient to recommend sertraline, topiramate, or zonisamide. In people with a BMI over 40 who fail to achieve ...