... P is the most common selenoprotein found in the plasma. It is unusual because in humans it contains 10 Sec ... Selenoproteins exist in all major domains of life, eukaryotes, bacteria and archaea. Among eukaryotes, selenoproteins appear to ... which shows the presence or absence of selenoprotein genes and accessory genes for the synthesis of selenoproteins in the ... Three selenoproteins, TXNRD1 (TR1), TXNRD2 (TR3) and glutathione peroxidase 4 (GPX4), have been shown to be essential in mouse ...
In molecular biology, the protein domain selenoprotein P (SelP) is the only known eukaryotic selenoprotein that contains ... Fujii M; Saijoh K; Kobayashi T; Fujii S; Lee MJ; Sumino K (October 1997). "Analysis of bovine selenoprotein P-like protein gene ... 2007). "The selenium-rich C-terminal domain of mouse selenoprotein P is necessary for the supply of selenium to brain and ... Binds to heparin in a pH-dependent manner Mostert V (April 2000). "Selenoprotein P: properties, functions, and regulation". ...
... is a protein that in humans is encoded by the SELENOO gene. This gene encodes a selenoprotein that is localized ... "Entrez Gene: Selenoprotein O". Retrieved 2018-05-18. Mabuchi H, Tatami R, Ueda K, Ueda R, Haba T, Kametani T, Watanabe A, ... The exact function of this selenoprotein is not known, but it is thought to have redox activity. [provided by RefSeq, Dec 2016 ... It is the largest mammalian selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon ...
Böck, A (2013). "Selenoprotein Synthesis". Encyclopedia of Biological Chemistry. pp. 210-213. doi:10.1016/B978-0-12-378630- ... Mix, H; Lobanov, A; Gladyshev, V (2007). "SECIS elements in the coding regions of selenoprotein transcripts are functional in ... In 2003, a landmark paper described the identification of all known selenoproteins in humans: 25 in total. Similar analyses ...
Liu, Junqiu (2012). Selenoprotein and Mimics. Springer. pp. 289-302. ISBN 978-3-642-22236-8. Huang, Michael (2001). "Room ...
These programs have been used in searches for novel selenoproteins. The SECIS element is found in a wide variety of organisms ... Mix H, Lobanov AV, Gladyshev VN (2007). "SECIS elements in the coding regions of selenoprotein transcripts are functional in ... Wilting R, Schorling S, Persson BC, Böck A (March 1997). "Selenoprotein synthesis in archaea: identification of an mRNA element ... Rother M, Resch A, Wilting R, Böck A (2001). "Selenoprotein synthesis in archaea". BioFactors. 14 (1-4): 75-83. doi:10.1002/ ...
Selenoprotein W is a protein that in humans is encoded by the SEPW1 gene. This gene encodes a selenoprotein, which contains a ... "Entrez Gene: SEPW1 selenoprotein W, 1". Whanger PD (December 2000). "Selenoprotein W: a review". Cellular and Molecular Life ... Overview of all the structural information available in the PDB for UniProt: P63300 (Mouse Selenoprotein W) at the PDBe-KB. v t ... The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for ...
Selenoprotein P is a better indicator of selenium nutritional status, and full expression of it would require more than 66 µg/ ... Papp, Laura Vanda; Lu, Jun; Holmgren, Arne; Khanna, Kum Kum (2007). "From Selenium to Selenoproteins: Synthesis, Identity, and ... Moosmann, B; Behl, C (2004). "Selenoprotein synthesis and side-effects of statins". Lancet. 363 (9412): 892-4. doi:10.1016/ ... Moosmann, B; Behl, C (2004). "Selenoproteins, cholesterol-lowering drugs, and the consequences: Revisiting of the mevalonate ...
Papp, Laura Vanda; Lu, Jun; Holmgren, Arne; Khanna, Kum Kum (1 July 2007). "From Selenium to Selenoproteins: Synthesis, ... Driscoll DM, Copeland PR (2003). "Mechanism and regulation of selenoprotein synthesis". Annual Review of Nutrition. 23 (1): 17- ...
15 kDa selenoprotein is a protein that in humans is encoded by the SEP15 gene. Two alternatively spliced transcript variants ... Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein ... The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for ... This protein is a selenoprotein only found in eukaryotes. This domain has a thioredoxin-like domain and a surface accessible ...
"Entrez Gene: SEPX1 selenoprotein X, 1". Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches ... The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for ... Lescure A, Gautheret D, Carbon P, Krol A (Feb 2000). "Novel selenoproteins identified in silico and in vivo by using a ... This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is ...
Selenoprotein N is a protein that in humans is encoded by the SEPN1 gene. This gene encodes a selenoprotein, which contains a ... The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for ... Lescure A, Gautheret D, Carbon P, Krol A (Dec 1999). "Novel selenoproteins identified in silico and in vivo by using a ... "Entrez Gene: SEPN1 selenoprotein N, 1". "Radiography data for Sepn1". Wellcome Trust Sanger Institute. "Salmonella infection ...
Selenoprotein S, also known as SELS, is a human gene. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) ... "Entrez Gene: SELS selenoprotein S". Ye, Yihong; Shibata Yoko; Yun Chi; Ron David; Rapoport Tom A (Jun 2004). "A membrane ... The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for ... 2007). "The role of the selenoprotein S (SELS) gene -105G>A promoter polymorphism in inflammatory bowel disease and regulation ...
Most selenoproteins contain a single selenocysteine residue. Selenoproteins that exhibit catalytic activity are called ... Selenoproteins contain selenocysteine residues. Selenocysteine is an analogue of the more common cysteine with selenium in ... When cells are grown in the absence of selenium, translation of selenoproteins terminates at the UGA codon, resulting in a ... Böck A, Forchhammer K, Heider J, Baron C (December 1991). "Selenoprotein synthesis: an expansion of the genetic code". Trends ...
Böck, A.; Forchhammer, K.; Heider, J.; Baron, C. (1991). "Selenoprotein synthesis: An expansion of the genetic code". Trends in ...
Selenoprotein P transports the trace element selenium from the liver to the testes and brain, and binds to ApoER2 in these ... Mice that have had their ApoER2 or Selenoprotein P expression knocked out show impaired spermatozoa development and decreased ... Burk RF, Hill KE (November 2009). "Selenoprotein P-expression, functions, and roles in mammals". Biochim. Biophys. Acta. 1790 ( ... "Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability". Nature Chemical Biology. 18 (7): 751- ...
Candidate for selenium delivery protein in selenoprotein synthesis". The Journal of Biological Chemistry. 275 (9): 6195-200. ... Labunskyy VM, Hatfield DL, Gladyshev VN (July 2014). "Selenoproteins: molecular pathways and physiological roles". ... enzyme participates in selenoamino acid metabolism by recycling Se from selenocysteine during the degradation of selenoproteins ...
Lee BC, Dikiy A, Kim HY, Gladyshev VN (2009). "Functions and evolution of selenoprotein methionine sulfoxide reductases". ...
Lee BC, Dikiy A, Kim HY, Gladyshev VN (2009). "Functions and evolution of selenoprotein methionine sulfoxide reductases". ...
St Germain DL, Galton VA (August 1997). "The deiodinase family of selenoproteins". Thyroid. 7 (4): 655-68. doi:10.1089/thy. ...
Selenoprotein P is a protein that in humans is encoded by the SEPP1 gene. This gene encodes a selenoprotein containing multiple ... "Entrez Gene: SEPP1 selenoprotein P, plasma, 1". Burk and Hill 2009 "Selenop selenoprotein P [Mus musculus (house mouse)] - Gene ... This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues (human, rat, mouse) per ... Hill KE, Lloyd RS, Yang JG, Read R, Burk RF (June 1991). "The cDNA for rat selenoprotein P contains 10 TGA codons in the open ...
Obata, T.; Y. Shiraiwa (2005). "A novel eukaryotic selenoprotein in the haptophyte alga Emiliania huxleyi". Journal of ...
"Substrate-specific selenoprotein B of glycine reductase from Eubacterium acidaminophilum. Biochemical and molecular analysis". ...
v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 9, Selenoproteins, All ... is required for the translation of mammalian selenoprotein mRNAs". The EMBO Journal. 19 (2): 306-14. doi:10.1093/emboj/19.2.306 ... "SECIS-SBP2 interactions dictate selenocysteine incorporation efficiency and selenoprotein hierarchy". The EMBO Journal. 19 (24 ...
"Substrate-specific selenoprotein B of glycine reductase from Eubacterium acidaminophilum. Biochemical and molecular analysis". ...
Selenoprotein Canadian Reference Material of selenomethionine Whanger, P. D. (2002). "Selenocompounds in plants and animals and ...
"Substrate-specific selenoprotein B of glycine reductase from Eubacterium acidaminophilum. Biochemical and molecular analysis". ...
"Substrate-specific selenoprotein B of glycine reductase from Eubacterium acidaminophilum. Biochemical and molecular analysis". ...
... whereas GPX6 is a selenoprotein in humans with cysteine-containing homologues in rodents. In selenoproteins, the amino acid ... Ursini F, Heim S, Kiess M, Maiorino M, Roveri A, Wissing J, Flohé L (1999). "Dual function of the selenoprotein PHGPx during ... Sneddon AA, Wu HC, Farquharson A, Grant I, Arthur JR, Rotondo D, Choe SN, Wahle KW (2004). "Regulation of selenoprotein GPx4 ... Foresta C, Flohé L, Garolla A, Roveri A, Ursini F, Maiorino M (2003). "Male fertility is linked to the selenoprotein ...
Selenoprotein T contains a selenocysteine (Sec) residue at its active site. selenoprotein GRCh38: Ensembl release 89: ... Selenoprotein T, also known as SELT, is a protein that in humans is encoded by the SELT gene. The selenocysteine is encoded by ... "Entrez Gene: SELT selenoprotein T". Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico ... The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for ...