Lipodermatosclerosis: Lipodermatosclerosis (also known as "Chronic panniculitis with lipomembranous changes," "Hypodermitis sclerodermiformis," "Sclerosing panniculitis," and "Stasis panniculitis") is a skin and connective tissue disease. It is a form of lower extremity panniculitis, Bruce AJ.Systemic sclerodermaTour SignalDermal equivalent: The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into a collagen gel.Telangiectasia macularis eruptiva perstans: Telangiectasia macularis eruptiva perstans is persistent, pigmented, asymptomatic eruption of macules usually less than 0.5 cm in diameter with a slightly reddish-brown tinge.Staining of the nail plate: Staining of the nail plate may occur due to nicotine, dyes (including hair dyes and nail polish), potassium permanganate, mercury compounds, hydroquinone, elemental iron, mepacrine, photographic developer, anthralin, chrysarobin, glutaraldehyde, or resorcin.James, William; Berger, Timothy; Elston, Dirk (2005).Dermal fibroblast: Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from injury. Using organelles (particularly the rough endoplasmic reticulum), dermal fibroblasts generate and maintain the connective tissue which unites separate cell layers.Papillary dermis: The papillary dermis is the uppermost layer of the dermis. It intertwines with the rete ridges of the epidermis and is composed of fine and loosely arranged collagen fibers.Autoantibody: An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, (notably lupus erythematosus), are caused by such autoantibodies.Anti-dsDNA antibodies: Anti-dsDNA antibodies are a group of anti-nuclear antibodies and their target antigen is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories.SclerodactylyN-terminal telopeptide: In bone physiology, the N-terminal telopeptide (or more formally, amino-terminal collagen crosslinks, and known by the acronym NTX) is a [that can be used as a biomarker] to measure the rate of [[bone turnover. NTX can be measured in the urine (uNTX) or serum (serum NTX).K-type main-sequence star: A K-type main-sequence star (K V), also referred to as an orange dwarf orOtto MarburgNon-specific interstitial pneumonia: Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia.Undifferentiated connective tissue diseaseGladys Lounsbury Hobby: Gladys Lounsbury Hobby (November 19, 1910 – July 4, 1993), born in New York City, was an American microbiologist who helped to move penicillin from a laboratory discovery to mass production during World War II.Ulcerative dermatitis: Ulcerative dermatitis is a skin disorder in rodents associated with bacterial growth often initiated by self-trauma due to a possible allergic response. Although other organisms can be involved, bacteria culture frequently shows Staphylococcus aureus.CTGF: CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers.CollagenCombined pulmonary fibrosis and emphysema: Combined pulmonary fibrosis and emphysema describes a medical syndrome involving both pulmonary fibrosis and emphysema. The combination is most commonly found in male smokers.Autoimmune diseasePulmonary Hypertension Association: The Pulmonary Hypertension Association (PHA) is a 501(c) organization non-profit support, education, advocacy and awareness association for pulmonary hypertension (PH). It provides information to the public about the illness and acts as a support group for those with the disease, providing medical provider location services and emotional support for those suffering from the illness.Annals of the Rheumatic Diseases: The Annals of the Rheumatic Diseases is a peer-reviewed medical journal. It is co-owned by the BMJ Group and the European League Against Rheumatism and covers all aspects of rheumatology, including musculoskeletal conditions, arthritis, and connective tissue diseases.PUVA-induced acrobullous dermatosis: PUVA-induced acrobullous dermatosis is a cutaneous condition characterized by the sudden occurrence of tense blisters, usually on the distal extremities, during long-term PUVA therapyEsophageal disease: Esophageal diseases can derive from congenital conditions, or they can be acquired later in life.Silicone resin: rightRibonucleoprotein: Ribonucleoprotein (RNP) is a nucleoprotein that contains RNA, i.e.Type I topoisomerase: In molecular biology Type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA, relax the strand, and reanneal the strand. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB.CentromereLinear IgA bullous dermatosis: Linear IgA bullous dermatosis (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected.James, William; Berger, Timothy; Elston, Dirk (2005).Dorsal carpal branch of the ulnar artery: The dorsal carpal branch of the ulnar artery arises from the ulnar artery immediately above the pisiform bone, and winds backward beneath the tendon of the flexor carpi ulnaris; it passes across the dorsal surface of the carpus beneath the extensor tendons, to anastomose with a corresponding branch of the radial artery.PenicillaminePrayer bump: A zebibah (Arabic زبيبة zabība, "raisin"), also known as a zabiba or zebiba, or browneye, is a mark on the forehead of some Muslims, apparently due to the friction generated by repeated contact of the forehead with the prayer mat during daily prayers.CapillaryOtospondylomegaepiphyseal dysplasia: Otospondylomegaepiphyseal dysplasia (OSMED) is an autosomal recessive disorder of bone growth that results in skeletal abnormalities, severe hearing loss, and distinctive facial features. The name of the condition indicates that it affects hearing (oto-) and the bones of the spine (spondylo-), and enlarges the ends of bones (megaepiphyses).Breast prosthesesBeare–Stevenson cutis gyrata syndrome: Beare–Stevenson cutis gyrata syndrome is a rare genetic disorder characterized by craniosynostosis (premature fusion of certain bones of the skull, sometimes resulting in a characteristic 'cloverleaf skull'; further growth of the skull is prevented, and therefore the shape of the head and face is abnormal) and a specific skin abnormality, called cutis gyrata, characterized by a furrowed and wrinkled appearance (particularly in the face and on the palms and soles of the feet); thick, dark, velvety areas of skin (acanthosis nigricans) are sometimes found on the hands and feet and in the groin.http://ghr.Systemic lupus erythematosus and pregnancy: For women with systemic lupus erythematosus (SLE), pregnancy can present some particular challenges for both mother and child.Wedge Island (South Australia): Wedge Island}}Functional gastrointestinal disorder: Functional gastrointestinal disorders (FGID) include a number of separate idiopathic disorders which affect different parts of the gastrointestinal tract and involve visceral hypersensitivity and impaired gastrointestinal motility. Heightened mast cell activation is a common factor among all FGIDs that contributes to visceral hypersensitivity as well as epithelial, neuromuscular, and motility dysfunction.Chronic lung diseaseDermatomyositis: - (ILDS M33.910)Ultraviolet light therapyTamponade