SOX genes (SRY-related HMG-box genes) encode a family of transcription factors that bind to the minor groove in DNA, and belong ... In mouse and human the members of the groups are: SoxA: SRY SoxB1: SOX1, SOX2, SOX3 SoxB2: SOX14, SOX21 SoxC: SOX4, SOX11, ... Sox 2 is also a transcription factor in the maintenance of pluripotency in both Early Embryos and ES Cells. Granule cells then ... transcription factors". Int. J. Biochem. Cell Biol. 39 (12): 2195-214. doi:10.1016/j.biocel.2007.05.019. PMC 2080623. PMID ...