The SOX gene family encodes transcription factors. It is suggested the three members of the SOXB1 group have redundant roles in ... SOX1, SOX2 and SOX3, members of the SOX gene family (specifically the SOXB1 group), contain transcription factors related to ... SOX1 is a gene that encodes a transcription factor with a HMG-box (high mobility group) DNA-binding domain and functions ... In ectodermal cells committed to a certain cell fate, SOX1 has shown to be one of the earliest transcription factors expressed ...

Schreiber J, Sock E, Wegner M (April 1997). "The regulator of early gliogenesis glial cells missing is a transcription factor ... In molecular biology, the GCM transcription factors are a family of proteins which contain a GCM motif. The GCM motif is a ... In GCM transcription factors the N-terminal moiety contains a DNA-binding domain of 150 amino acids. Sequence conservation is ...

Transcription factor SOX-21 is a protein that in humans is encoded by the SOX21 gene. It is a member of the Sox gene family of ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-70. doi:10.1016 ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 13, Transcription factors ... transcription factors. In the chick embryo, Sox21 promotes neuronal cellular differentiation by counteracting the activity of ...

... and the International Workshop on Sox Transcription Factors (2005 - ). He was organizer of the Cold Spring Harbor (USA) ... "Trans-activation and DNA-binding properties of the transcription factor, Sox-18". Nucleic Acids Research. 23 (14): 2626-2628. ... "Phylogeny of the SOX Family of Developmental Transcription Factors Based on Sequence and Structural Indicators". Developmental ... Koopman found that the human and mouse genomes contain 20 Sox genes, and he proposed the naming system for Sox genes that ...

Transcription factor SOX-18 is a protein that in humans is encoded by the SOX18 gene. This gene encodes a member of the SOX ( ... Wilson M, Koopman P (August 2002). "Matching SOX: partner proteins and co-factors of the SOX family of transcriptional ... "Sequence and expression of Sox-18 encoding a new HMG-box transcription factor". Gene. 161 (2): 223-5. doi:10.1016/0378-1119(95) ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-70. doi:10.1016 ...

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of ... SOX7 is a transcription factor that comes from the SRY-related HMG-Box family of transcription factors. These factors play a ... Séguin CA, Draper JS, Nagy A, Rossant J (August 2008). "Establishment of endoderm progenitors by SOX transcription factor ... "SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signalling ...

The gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, located on Chromosome 8 q11.23. Its ... Séguin CA, Draper JS, Nagy A, Rossant J (August 2008). "Establishment of endoderm progenitors by SOX transcription factor ... February 2015). "Transcription factor binding dynamics during human ES cell differentiation". Nature. 518 (7539): 344-9. ... MacCarthy CM, Malik V, Wu G, et al., & Velychko S (September 2022). "Enhancing Sox/Oct cooperativity induces higher-grade ...

Transcription factor SOX-5 is a protein that in humans is encoded by the SOX5 gene. This gene encodes a member of the SOX (SRY- ... Bowles J, Schepers G, Koopman P (Nov 2000). "Phylogeny of the SOX family of developmental transcription factors based on ... Wilson M, Koopman P (Aug 2002). "Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-70. doi:10.1016 ...

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG ... SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to ... Sox12 belongs to the SoxC group of Sox family of transcription factors, together with Sox4 and Sox11. Sox12-null knockout mice ... Bowles J, Schepers G, Koopman P (2001). "Phylogeny of the SOX family of developmental transcription factors based on sequence ...

SOX genes (SRY-related HMG-box genes) encode a family of transcription factors that bind to the minor groove in DNA, and belong ... Sox 2 is also a transcription factor in the maintenance of pluripotency in both Early Embryos and ES Cells. Granule cells then ... Sox) transcription factors". Int. J. Biochem. Cell Biol. 39 (12): 2195-214. doi:10.1016/j.biocel.2007.05.019. PMC 2080623. PMID ... "Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators". Dev. Biol. 227 ...

Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of ... Bowles J, Schepers G, Koopman P (November 2000). "Phylogeny of the SOX family of developmental transcription factors based on ... Wilson M, Koopman P (August 2002). "Matching SOX: partner proteins and co-factors of the SOX family of transcriptional ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-70. doi:10.1016 ...

Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX ( ... Schlierf B, Lang S, Kosian T, Werner T, Wegner M (November 2011). "The high-mobility group transcription factor Sox10 interacts ... Revised: 20 September 2019 Potterf SB, Furumura M, Dunn KJ, Arnheiter H, Pavan WJ (July 2000). "Transcription factor hierarchy ... family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded ...

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of ... Koopman, P; Schepers, G; Brenner, S; Venkatesh, B (2004). "Origin and diversity of the SOX transcription factor gene family: ...

Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. SOX-9 recognizes the sequence CCTTGAG along ... Overview of all the structural information available in the PDB for UniProt: P48436 (Human Transcription factor SOX-9) at the ... Overview of all the structural information available in the PDB for UniProt: Q04887 (Mouse Transcription factor SOX-9) at the ... The process starts when the transcription factor Testis determining factor (encoded by the sex-determining region SRY of the Y ...

Transcription factor SOX-3 is a protein that in humans is encoded by the SOX3 gene. This gene encodes a member of the SOX (SRY- ... SRY-box transcription factor 3, SOX3, is a transcription factor that is encoded by the SOX3 gene. This gene is responsible for ... Bowles J, Schepers G, Koopman P (November 2000). "Phylogeny of the SOX family of developmental transcription factors based on ... Regarding its developmental facet, SOX3, alongside other SOX transcription factors, ensures the proper formation of the ...

Transcription factor SOX-13 is a protein that in humans is encoded by the SOX13 gene. This gene encodes a member of the SOX ( ... Wilson M, Koopman P (Aug 2002). "Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-70. doi:10.1016 ... family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The ...

Transcription factor SOX-8 is a protein that in humans is encoded by the SOX8 gene. This gene encodes a member of the SOX (SRY- ... 2006). "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 16, Transcription factors ... family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. ...

Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend ... Transcription factor SOX-6 is a protein that in humans is encoded by the SOX6 gene. The SOX gene family encodes a group of ... May 2020). "Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing ... Transcription factors, All stub articles, Human chromosome 11 gene stubs). ...

Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene. This intronless gene encodes a member of ... Overview of all the structural information available in the PDB for UniProt: P35716 (Human Transcription factor SOX-11) at the ... Wilson M, Koopman P (Aug 2002). "Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators ... Gozé C, Poulat F, Berta P (Jun 1993). "Partial cloning of SOX-11 and SOX-12, two new human SOX genes". Nucleic Acids Research. ...

Transcription factor SOX-14 is a protein that in humans is encoded by the SOX14 gene. This intronless gene encodes a member of ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-70. doi:10.1016 ... the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 3, Transcription factors ...

"The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". Nucleic Acids ... The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in ... Transcription factors, All stub articles, Human chromosome 12 gene stubs). ... "At least three human homeoboxes on chromosome 12 belong to the same transcription unit". Nucleic Acids Res. 16 (12): 5379-90. ...

"The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". Nucleic Acids ... This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene ... In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C ... Transcription factors, All stub articles, Human chromosome 7 gene stubs). ...

"The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". Nucleic Acids ... "Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors". FEBS Lett. 499 (3): 274-8. doi:10.1016/ ... "Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors". FEBS Lett. 499 (3): 274-8. doi:10.1016/ ...

"The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". Nucleic Acids ... Oligodendrocyte transcription factor (OLIG2) is a basic helix-loop-helix (bHLH) transcription factor encoded by the OLIG2 gene ... Lin YW, Deveney R, Barbara M, Iscove NN, Nimer SD, Slape C, Aplan PD (Aug 2005). "OLIG2 (BHLHB1), a bHLH transcription factor, ... Lin YW, Deveney R, Barbara M, Iscove NN, Nimer SD, Slape C, Aplan PD (Aug 2005). "OLIG2 (BHLHB1), a bHLH transcription factor, ...

"The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". Nucleic Acids ... "The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-β ( ... The protein functions as a transcription coactivator, enhancing the DNA-binding activity of serum response factor, a protein ... For example, PRRX1 inhibits adipogenesis by activating transforming growth factor-beta (TGF-beta) signaling, and also acts ...

2006). "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 9, Transcription factors ...

... is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of ... Overview of all the structural information available in the PDB for UniProt: P48432 (Mouse Transcription factor SOX-2) at the ... and nomenclature of the mouse and human sox transcription factor gene families". Developmental Cell. 3 (2): 167-170. doi: ... Human Transcription factor SOX-2) at the PDBe-KB. ... March 2004). "Down-regulation of a gastric transcription factor ...

2006). "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors". ... Seeler JS, Muchardt C, Suessle A, Gaynor RB (1994). "Transcription factor PRDII-BF1 activates human immunodeficiency virus type ... Transcription factors, All stub articles, Human chromosome 6 gene stubs). ...

Sox family: The Sox family of transcription factors is associated with maintaining pluripotency similar to Oct-3/4, although it ... The original set of reprogramming factors (also dubbed Yamanaka factors) are the transcription factors Oct4 (Pou5f1), Sox2, ... genomic integration of the transcription factors limits the utility of the transcription factor approach because of the risk of ... other transcription factors in the Sox family have been found to work as well in the induction process. Sox1 yields iPSCs with ...

... like SOX, to be expressed. These genes encode transcription factors, which alter the genomic expression of these cells, ...