Bach M, Winkelmann G, Lührmann R (Aug 1989). "20S small nuclear ribonucleoprotein U5 shows a surprisingly complex protein ... "Conservation between yeast and man of a protein associated with U5 small nuclear ribonucleoprotein". Nature. 342 (6251): 819-21 ... "The mammalian analogue of the yeast PRP8 splicing protein is present in the U4/5/6 small nuclear ribonucleoprotein particle and ... Achsel T, Ahrens K, Brahms H, Teigelkamp S, Lührmann R (Nov 1998). "The human U5-220kD protein (hPrp8) forms a stable RNA-free ...

This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the ... WD repeat domain 57 (U5 snRNP specific), also known as WDR57, is a gene found in many organisms, including, but not limited to ... "Entrez Gene: WDR57 WD repeat domain 57 (U5 snRNP specific)". Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom- ... Achsel T, Ahrens K, Brahms H, Teigelkamp S, Lührmann R (Nov 1998). "The human U5-220kD protein (hPrp8) forms a stable RNA-free ...

"Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae ... Black DL, Pinto AL (August 1989). "U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction ... Berget SM, Robberson BL (August 1986). "U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing ... Black DL, Steitz JA (August 1986). "Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein". Cell. 46 ...

U4atac small nuclear (U12-dependent splicing) is a small nuclear RNA that in humans is encoded by the RNU4ATAC gene. The small ... In addition to the encoded RNA, this ribonucleoprotein complex consists of U11, U12, U5, and U6atac snRNAs. The U12-dependent ... Tarn WY, Steitz JA (Sep 1996). "Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns". Science ... Shukla GC, Padgett RA (Jan 2004). "U4 small nuclear RNA can function in both the major and minor spliceosomes". Proceedings of ...

Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor". The ... Poukka H, Aarnisalo P, Santti H, Jänne OA, Palvimo JJ (January 2000). "Coregulator small nuclear RING finger protein (SNURF) ... The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear ... People with too little sex hormones can be short during puberty but end up taller as adults as in androgen insensitivity ...

Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor". J. ... Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor". J. ... 2005). "The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but ... The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 ...

... component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein". Nature ... This pattern is also seen in HeLa cell lines when treated with Casiopenias, small molecules with an active Cu2+ that allow the ... Lamping E, Niimi M, Cannon RD (July 2013). "Small, synthetic, GC-rich mRNA stem-loop modules 5' proximal to the AUG start-codon ... In addition, there are two predicted nuclear localization sequences in WDCP, starting at residues 401 and 581. Immunostaining ...

U5 small nuclear ribonucleoprotein 200 kDa helicase is an enzyme that in humans is encoded by the SNRNP200 gene. GRCh38: ... Achsel T, Ahrens K, Brahms H, Teigelkamp S, Luhrmann R (Nov 1998). "The Human U5-220kD Protein (hPrp8) Forms a Stable RNA-Free ... Laggerbauer B, Achsel T, Luhrmann R (May 1998). "The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro". Proc ... Lauber J, Fabrizio P, Teigelkamp S, Lane WS, Hartmann E, Luhrmann R (Oct 1996). "The HeLa 200 kDa U5 snRNP-specific protein and ...

116 kDa U5 small nuclear ribonucleoprotein component is a protein that in humans is encoded by the EFTUD2 gene. Heterozygous ... Peng R, Dye BT, Pérez I, Barnard DC, Thompson AB, Patton JG (Oct 2002). "PSF and p54nrb bind a conserved stem in U5 snRNA". RNA ... Achsel T, Ahrens K, Brahms H, Teigelkamp S, Lührmann R (Nov 1998). "The human U5-220kD protein (hPrp8) forms a stable RNA-free ... Achsel T, Ahrens K, Brahms H, Teigelkamp S, Lührmann R (Nov 1998). "The human U5-220kD protein (hPrp8) forms a stable RNA-free ...

The first molecular-resolution reconstruction of U4/U6.U5 triple small nuclear ribonucleoprotein (tri-snRNP) complex was ... Small nuclear RNA (snRNA) molecules bind to specific proteins to form a small nuclear ribonucleoprotein complex (snRNP, ... small nuclear ribonucleoproteins, pronounced "snurps"). The snRNAs that make up the major spliceosome are named U1, U2, U4, U5 ... Each spliceosome is composed of five small nuclear RNAs (snRNA) and a range of associated protein factors. When these small ...

"SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the ...

"Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae ... It forms the U5 snRNP (small nuclear ribonucleoprotein) by associating with several proteins including Prp8 - the largest and ... Page for U5 spliceosomal RNA at Rfam v t e (GO template errors, Small nuclear RNA, Spliceosome, RNA splicing, All stub articles ... U5 snRNA is a small nuclear RNA (snRNA) that participates in RNA splicing as a component of the spliceosome. ...

... of Rev from human immunodeficiency virus type 1 specifically blocks the entry of U4/U6.U5 small nuclear ribonucleoprotein in ... U2 small nuclear ribonucleoprotein A' is a protein that in humans is encoded by the SNRPA1 gene. SNRPA1 has been shown to ... "Entrez Gene: SNRPA1 small nuclear ribonucleoprotein polypeptide A'". Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI ... protein complex bound to a fragment of U2 small nuclear RNA". Nature. 394 (6694): 645-50. Bibcode:1998Natur.394..645P. doi: ...

U5, and U6) and over 150 proteins. The snRNAs, along with their associated proteins, form ribonucleoprotein complexes (snRNPs ... Through the study of small nuclear ribonucleoproteins (snRNPs) and small nucleolar (sno)RNPs we have been able to better ... Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the ... Small+Nuclear+RNA at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Small+Nucleolar+RNA at the U.S. ...

U4/U6 and U5". Nucleic Acids Research. 18 (22): 6475-84. doi:10.1093/nar/18.22.6475. PMC 332598. PMID 1701240. "Entrez Gene: ... Small nuclear ribonucleoprotein D1 has been shown to interact with: CDC5L, CLNS1A, DDX20, SMN1, and Small nuclear ... Small nuclear ribonucleoprotein Sm D1 is a protein that in humans is encoded by the SNRPD1 gene. This gene encodes a small ... SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa". Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (Dec ...

U4/U6 and U5". Nucleic Acids Res. 18 (22): 6475-84. doi:10.1093/nar/18.22.6475. PMC 332598. PMID 1701240. "Entrez Gene: SNRPD2 ... Small nuclear ribonucleoprotein D2 has been shown to interact with DDX20, Small nuclear ribonucleoprotein D1, Small nuclear ... It belongs to the small nuclear ribonucleoprotein core protein family, and is required for pre-mRNA splicing and small nuclear ... Small nuclear ribonucleoprotein Sm D2 is a protein that in humans is encoded by the SNRPD2 gene. ...

Small nuclear ribonucleoproteins (snRNPs) assemble in a tightly orchestrated and regulated process that involves both the cell ... human U5 snRNP, U4/U6 di-snRNP, U4/U6∙U5 tri-snRNP. The further progress determining the structures and functions of snRNPs and ... ISBN 0-07-284611-9. Montzka KA, Steitz JA (1988). "Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, ... snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre- ...

"Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles". J. Biol. Chem. 264 (10): ... The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ... Small nuclear ribonucleoprotein-associated proteins B and B' is a protein that in humans is encoded by the SNRPB gene. ... "Entrez Gene: SNRPB small nuclear ribonucleoprotein polypeptides B and B1". Charroux B, Pellizzoni L, Perkinson RA, Shevchenko A ...

... a nuclear organelle (cellular sub-organelle) involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps ... U5 and U12. The first scaRNA identified was U85. It is unlike typical snoRNAs in that it is a composite C/D box and H/ACA box ... Darzacq X, Jády BE, Verheggen C, Kiss AM, Bertrand E, Kiss T (June 2002). "Cajal body-specific small nuclear RNAs: a novel ... In molecular biology, Small Cajal body-specific RNA 1 (also known as SCARNA1 or ACA35) is a small nucleolar RNA found in Cajal ...

The antigens of the anti-Sm antibodies are the core units of the small nuclear ribonucleoproteins (snRNPs), termed A to G, and ... will bind to the U1, U2, U4, U5 and U6 snRNPs. Most commonly, the antibodies are specific for the B, B' and D units. Molecular ... Anti-nuclear ribonucleoprotein (anti-nRNP) antibodies, also known as anti-U1-RNP antibodies, are found in 30-40% of SLE. They ... Nuclear dot patterns show between 13 and 25 nuclear dots in interphase cells and are produced by anti-sp100 antibodies. ...

... ribonucleoprotein, u4-u6 small nuclear MeSH D12.776.664.962.500.875.620 - ribonucleoprotein, u5 small nuclear MeSH D12.776. ... ribonucleoprotein, u1 small nuclear MeSH D12.776.664.962.500.875.605 - ribonucleoprotein, u2 small nuclear MeSH D12.776.664.962 ... ribonucleoproteins, small nuclear MeSH D12.776.664.962.500.875.590 - ribonucleoproteins, small nucleolar MeSH D12.776.664.962. ... heterogeneous-nuclear ribonucleoprotein d MeSH D12.776.664.962.500.500.400 - heterogeneous-nuclear ribonucleoprotein group f-h ...

... ribonucleoprotein, u4-u6 small nuclear MeSH D12.776.157.725.500.875.620 - ribonucleoprotein, u5 small nuclear MeSH D12.776. ... ribonucleoprotein, u1 small nuclear MeSH D12.776.157.725.500.875.605 - ribonucleoprotein, u2 small nuclear MeSH D12.776.157.725 ... ribonucleoproteins, small nuclear MeSH D12.776.157.725.500.875.590 - ribonucleoproteins, small nucleolar MeSH D12.776.157.725. ... heterogeneous-nuclear ribonucleoprotein d MeSH D12.776.157.725.500.500.400 - heterogeneous-nuclear ribonucleoprotein group f-h ...

Splicing is catalyzed by the spliceosome, a large RNA-protein complex composed of five small nuclear ribonucleoproteins (snRNPs ... The U5/U4/U6 snRNP trimer binds, and the U5 snRNP binds exons at the 5' site, with U6 binding to U2; Complex B* The U1 snRNP is ... a complex of small nuclear ribonucleoproteins (snRNPs). There exist self-splicing introns, that is, ribozymes that can catalyze ... In addition, a number of proteins including U2 small nuclear RNA auxiliary factor 1 (U2AF35), U2AF2 (U2AF65) and SF1 are ...

... s can interfere with pre-mRNA processing steps either by preventing splice-directing small nuclear ribonucleoproteins ... Preventing the binding of snRNP U1 (at the donor site) or U2/U5 (at the polypyrimidine moiety and acceptor site) can cause ... The small subunit of the ribosome usually starts by binding at the 5' end of the mRNA and is joined there by various other ... Morpholinos block access of other molecules to small (~25 base) specific sequences of the base-pairing surfaces of ribonucleic ...

2000). "Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin ... "The 20kD protein of human U4/U6.U5 tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD ... as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that ...

Small nuclear ribonucleoprotein Sm D3 is a protein that in humans is encoded by the SNRPD3 gene. The protein encoded by this ... U4/U6 and U5". Nucleic Acids Res. 18 (22): 6475-84. doi:10.1093/nar/18.22.6475. PMC 332598. PMID 1701240. Lehmeier T, Raker V, ... gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ... "Entrez Gene: SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa". Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, ...

A set of uridine-rich small nuclear RNA (snRNA) molecules was part of this complex, and given the names U1, U2, U4, U5 and U6. ... Small nuclear ribonucleoproteins (snRNPs) assemble in a tightly orchestrated and regulated process that involves both the cell ... far-reaching significance of a small nuclear ribonucleoprotein" (PDF). Cell. Mol. Life Sci. 61 (19-20): 2560-70. doi:10.1007/ ... "Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle". Nature. 401 (6749): 177-80. Bibcode: ...

... a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition". eLife. 4. doi:10.7554/eLife. ... Structures of the U5.U4/U6 tri-snRNP gave the first structural insights into the assembly of the spliceosome. Nagai's ... "Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A". Nature. 348 (6301): 515-520. Bibcode: ... protein complex bound to a fragment of U2 small nuclear RNA". Nature. 394 (6694): 645-650. Bibcode:1998Natur.394..645P. doi: ...

O-ribose methylation and pseudouridylation of small nuclear RNA (snRNA) U5 has been identified. This composite snoRNA contains ... snoRNA associates with at least four core proteins in an RNA/protein complex referred to as a small nucleolar ribonucleoprotein ... Darzacq X, Jády BE, Verheggen C, Kiss AM, Bertrand E, Kiss T (June 2002). "Cajal body-specific small nuclear RNAs: a novel ... SnoRNAs are classified under small nuclear RNA in MeSH. The HGNC, in collaboration with snoRNABase and experts in the field, ...

... is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein ... Following recruitment of the U2 snRNP and U5.U4/U6 tri-snRNP the spliceosome transfers the 5'-splice site from the U1 snRNA to ... "U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease". Proceedings of the National ... "Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease". The Journal of Biological Chemistry ...