... has also been used as a treatment for herpes simplex virus. One small study found that ribavirin treatment reduced ... The mechanism of action of ribavirin is not entirely clear. Ribavirin was patented in 1971 and approved for medical use in 1986 ... 1980). "Ribavirin: structure and antiviral activity relationships". Ribavirin: A Broad Spectrum Antiviral Agent. New York: ... "Ribavirin (Ibavyr)". Catie. 2022. Retrieved 22 August 2022. "PRODUCT INFORMATION REBETOL (RIBAVIRIN) CAPSULES" (PDF). TGA ...

"COPEGUS (RIBAVIRIN) TABLET, FILM COATED [GENENTECH, INC]". DailyMed. Genentech, Inc. February 2013. Retrieved 23 February 2014 ... List of adverse effects of ribavirin by frequency. Abdominal pain Anemia Anxiety Appetite loss Concentration impaired ... RIBAVIRIN) CAPSULES" (PDF). TGA eBusiness Services. Merck Sharp & Dohme (Australia) Pty Limited. 29 April 2013. Retrieved 23 ...

"Ribavirin History". News-Medical.net. 12 April 2010. Retrieved 19 February 2016. "Aerosolization of Ribavirin through a Mask, ... In 1985, ribavirin was approved under the name Virazole by the Food and Drug Administration for the treatment of respiratory ... In 1991, ICN created the SPAG-2 (Small Particle Aerosol Generator) nebulizer to administer an aerosolized form of ribavirin ... "Rebetol, Ribasphere (ribavirin) dosing, indications, interactions, adverse effects, and more". reference.medscape.com. ...

The antiviral medication ribavirin has been recommended, but evidence to support its use is weak. Descriptions of the disease ... Effective therapy with ribavirin". The New England Journal of Medicine. 314 (1): 20-26. doi:10.1056/NEJM198601023140104. ISSN ... Because of treatment with ribavirin, fatality rates have declined. There are about 300,000 to 500,000 cases which result in ... Eberhardt, KA; Mischlinger, J; Jordan, S; Groger, M; Günther, S; Ramharter, M (October 2019). "Ribavirin for the treatment of ...

Ribavirin was not given in these first two cases. Four years later, in 1994, a researcher was exposed to the virus in a level 3 ... Ribavirin is thought to be effective in treating the illness, similar to other arenaviruses. Compared to the patients who did ... He was successfully treated with ribavirin. A fifth case, also naturally acquired in upstate São Paulo, was reported in January ... not receive ribavirin, the patient who was treated with it had a shorter and less severe clinical course. Symptomatic control ...

When Viekira Pak was used without ribavirin, nausea, severe itching, and insomnia occurred in more than 5% of the subjects. ... The co-packaged dasabuvir and ombitasvir/paritaprevir/ritonavir is used in combination with ribavirin for the treatment of ... Some people taking dasabuvir are also treated with another antiviral medicine, ribavirin, in addition to ombitasvir/ ... Ribavirin may also additionally be used. These combinations result in a cure in more than 90% of people. It is taken by mouth. ...

... and Ribavirin. Gastroenterology 2009b; 136:856-862. (BLP articles lacking sources from July 2018, All BLP articles lacking ...

2010). "Ribavirin for Lassa fever postexposure prophylaxis". Emerg Infect Dis. 16 (12): 2009-11. doi:10.3201/eid1612.100994. ... Post-exposure prophylactic (preventive) ribavirin may be effective for some bunyavirus and arenavirus infections. VHF isolation ... Antiviral therapy with intravenous ribavirin may be useful in Bunyaviridae and Arenaviridae infections (specifically Lassa ...

Ribavirin has shown some efficacy in vitro and has been used by mouth during outbreaks,[citation needed] but there is uncertain ... Treatment is typically with supportive care, and the medication ribavirin may also help. CCHF cases are observed in a wide ... Alternatively, many scientists appear to believe that treatment of CCHF with ribavirin is more practical than prevention, but ... Cochrane Infectious Diseases Group) (June 2018). "Ribavirin for treating Crimean Congo haemorrhagic fever". The Cochrane ...

Other studies used ribavirin in combination showed similar promising results in head and neck cancer. Ribavirin impairs all of ... Subsequent ribavirin trials in AML in combination with antileukemic drugs again showed objective clinical responses including ... In the first clinical trials targeting eIF4E, old antiviral drug ribavirin was used as a m7G cap competitor which had ... In the first trial to ever target eIF4E, ribavirin monotherapy was demonstrated to inhibit eIF4E activity leading to objective ...

Use with ribavirin is not recommended during pregnancy. Pegylated interferon alfa-2a is in the alpha interferon family of ... For genotype 1 hepatitis C treated with pegylated interferon alfa-2a or pegylated interferon alfa-2b combined with ribavirin, ... For hepatitis C it is typically used together with ribavirin and cure rates are between 24 and 92%. For hepatitis B it may be ...

Ribavirin, m102.4 monoclonal antibody, and favipiravir were being studied as treatments as of 2019. Ribavirin has been studied ... While tentative evidence supports the use of ribavirin, it has not yet been studied in people with the disease. Specific ... In vitro studies and animal studies have shown conflicting results in the efficacy of ribavirin against NiV and Hendra, with ... May 2006). "Poly(I)-poly(C12U) but not ribavirin prevents death in a hamster model of Nipah virus infection". Antimicrobial ...

IFN-β 1b have been shown in an open label randomised controlled trial in combination with lopinavir/ ritonavir and ribavirin to ... Coronaviruses species possess an intrinsic resistance to ribavirin. Sofosbuvir/daclatasvir is a drug combination developed to ... These include favipiravir, remdesivir, ribavirin, triazavirin, and umifenovir. The combination of artesunate/pyronaridine was ...

430-434 Crotty S, Camerson SE, Andino R (2001). RNA virus error catastrophe: direct molecular test using ribavirin. Proceedings ...

Gish RG (January 2006). "Treating HCV with ribavirin analogues and ribavirin-like molecules". The Journal of Antimicrobial ... "Rebetol, Ribasphere (ribavirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. ...

February 2008). "In vitro efficacy of ribavirin against canine distemper virus". Antiviral Res. 77 (2): 108-113. doi:10.1016/j. ...

Gish RG (January 2006). "Treating HCV with ribavirin analogues and ribavirin-like molecules". The Journal of Antimicrobial ... It is a prodrug of ribavirin, active against a number of DNA and RNA viruses. Taribavirin has better liver-targeting than ... It is expected eventually to be the drug of choice for viral hepatitis syndromes in which ribavirin is active. These include ... Taribavirin is as active against influenza as ribavirin in animal models, with slightly less toxicity, so it may also ...

Crotty S, Cameron CE, Andino R (2001). "RNA virus error catastrophe: Direct molecular test by using ribavirin". Proceedings of ... "The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen". Nature Medicine. 6 (12): 1375-1379. doi:10.1038 ...

These experiments revealed that ribavirin-TP, which is made of similar building blocks to RNA, is incorporated into the viral ... He went on to demonstrate that ribavirin works by creating extreme mutation within viruses that forces them into genetic melt ... To study the mechanism of action of ribavirin-based antivirals, Cameron developed an analytical assay that could monitor ... Cameron developed lethal mutagenesis; an alternative mechanism of action of ribavirin that renders genes unable to function. He ...

As his condition worsened, he was treated with intravenous ribavirin. Conteh initially survived the critical stage of Lassa ...

Ribavirin also has shown some promise in treating arenaviral diseases. The disease was first detected in the 1950s in the Junín ...

Studies have shown that treating RNA viruses such as poliovirus with ribavirin produce results consistent with the idea that ... Crotty S, Cameron CE, Andino R (June 2001). "RNA virus error catastrophe: direct molecular test by using ribavirin". ...

This is the case of favipiravir (T-705; 6-fluoro-3-hydroxy-2-pirazinecarboxamide) and ribavirin (1-β-D-ribofuranosyl-1-H-1,2,4- ... For example, increased doses of the mutagen ribavirin reduces the infectivity of poliovirus. However, these models assume that ... Crotty S, Cameron CE, Andino R (June 2001). "RNA virus error catastrophe: direct molecular test by using ribavirin". ...

Pegylated interferon and ribavirin are useful in reducing viral load. Diffuse proliferative nephritis Colville D, Guymer R, ...

A combination of mycophenolate and ribavirin has been found to stop infection by and replication of dengue virus in vitro. It ... "Inhibition of dengue virus replication by mycophenolic acid and ribavirin". The Journal of General Virology. 87 (Pt 7): 1947-52 ...

ELECTRON: 100% Suppression of Viral Load through 4 Weeks' Post-treatment for Sofosbuvir + Ledipasvir (GS-5885) + Ribavirin for ... CROI 2013: Sofosbuvir + Ledipasvir + Ribavirin Combo for HCV Produces 100% Sustained Response Archived 2015-09-24 at the ... and ribavirin produced a 12-week post-treatment sustained virological response (SVR12) rate of 100% for both treatment-naive ... without interferon and ribavirin. On 10 October 2014 the FDA approved the combination product ledipasvir/sofosbuvir called ...

Treatment of children has been with interferon and ribavirin. The response to treatment is similar to that in adults. It shows ... Both pegylated interferon and ribavirin are unsuitable for use in pregnancy and infancy: newer methods of treatment are ...

During pregnancy when used with ribavirin it may cause harm to the baby while when used with sofosbuvir its safety is unclear. ... If pregnant women are exposed to any medication regimen containing ribavirin, they are encouraged to report this through the ... Simeprevir is administered as one capsule once daily with pegylated interferon and ribavirin for the treatment of genotype 1 or ... "Phase 3 Studies Show Simeprevir plus Interferon/Ribavirin Cures Most Patients in 24 Weeks". hivandhepatitis.com. 27 December ...

Intravenous ribavirin is effective against La Crosse encephalitis virus in the laboratory, and several studies in patients with ... In a trial with 15 children being infected with La Crosse viral encephalitis were treated at certain phases with ribavirin (RBV ... McJunkin, JE (October 2011). "Safety and pharmacokinetics of ribavirin for the treatment of la crosse encephalitis". The ...

"Rebetol- ribavirin capsule Rebetol- ribavirin liquid". DailyMed. Retrieved 26 January 2022. Bhatia HK, Singh H, Grewal N, Natt ... However, when used in combination with ribavirin or peginterferon alfa/ribavirin, or others, the contraindications applicable ... However, ribavirin, a medication that is often given together with sofosbuvir to treat hepatitis C, is assigned a Pregnancy ... Pregnant women with hepatitis C who take ribavirin have shown some cases of birth defects and death in their fetus. It is ...