Embryonal rhabdomyosarcoma
... is also known as PAX-fusion negative or fusion-negative rhabdomyosarcoma, as tumors of this subtype ... When examining embryonal rhabdomyosarcoma tumors vs. alveolar rhabdomyosarcoma tumors, a 2013 study had discovered that there ... Embryonal rhabdomyosarcoma is generally associated with better prognosis than alveolar rhabdomyosarcoma, with a five-year ... The heterogenous structure resembles striated muscle at various embryonal developmental stages. Embryonal rhabdomyosarcoma can ...
Sarcoma botryoides
... or botryoid sarcoma is a subtype of embryonal rhabdomyosarcoma, that can be observed in the walls of hollow ... Reynolds E, Logani S, Moller K, Horowitz I (2006). "Embryonal rhabdomyosarcoma of the uterus in a postmenopausal woman. Case ... Piver M, Rose P (1988). "Long-term follow-up and complications of infants with vulvovaginal embryonal rhabdomyosarcoma treated ... Hilgers R (1975). "Pelvic exenteration for vaginal embryonal rhabdomyosarcoma: a review". Obstet Gynecol. 45 (2): 175-80. PMID ...
Rhabdomyoblast
Outlier case reports have been presented, including the aggressive prognosis of embryonal rhabdomyosarcoma and the simultaneous ... Balitzer D, McCalmont TH, Horvai AE (2015-12-10). "Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma ... Extensive research is needed for a more detailed report; however, embryonal rhabdomyosarcoma and rhabdomyoblast differentiation ... that the neoplasm may be a variant embryonal rhabdomyosarcoma. A 'nephroblastoma, also referred to as Wilms' tumor, arises from ...
Santosh G. Honavar
"Orbital embryonal rhabdomyosarcoma in association with neurofibromatosis type 1". Ophthalmic Plast Reconstr Surg. 23 (2): 147-8 ... "Primary ophthalmic rhabdomyosarcoma in 33 patients". Trans Am Ophthalmol Soc. 99: 133-42, discussion 142-3. PMC 1359004. PMID ... "Clinical spectrum of primary ophthalmic rhabdomyosarcoma". Ophthalmology. 108 (12): 2284-92. doi:10.1016/s0161-6420(01)00840-5 ...
PAX7
Tiffin N, Williams RD, Shipley J, Pritchard-Jones K (July 2003). "PAX7 expression in embryonal rhabdomyosarcoma suggests an ... A link to the metastatic potential of embryonal rhabdomyosarcoma and cutaneous malignant melanoma?". Histology and ... "In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma" (PDF). Human Molecular Genetics ... "PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's ...
Enterovirus 71
Lin TY, Chu C, Chiu CH (October 2002). "Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells ...
Enterovirus
Lin TY, Chu C, Chiu CH (October 2002). "Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells ...
RMST (gene)
It is expressed at higher levels in alveolar rhabdomyosarcoma than in embryonal rhabdomyosarcoma. In the brain, RMST is ... Rhabdomyosarcoma 2 associated transcript (RMST) is a long non-coding RNA. In humans, it is located on chromosome 12q21. ... "Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between rhabdomyosarcoma subtypes". ...
Rhabdomyosarcoma
The four subtypes are embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma, pleomorphic rhabdomyosarcoma, and spindle-cell/ ... Pleomorphic rhabdomyosarcoma (undifferentiated rhabdomyosarcoma), also known as anaplastic rhabdomyosarcoma, is defined by the ... embryonal, alveolar, pleomorphic, and spindle-cell/sclerosing.[citation needed] Embryonal rhabdomyosarcoma (ERMS) is the most ... Embryonal rhabdomyosarcoma is the most common type and comprises about 60% of cases. Outcomes vary considerably, with five-year ...
Spindle cell rhabdomyosarcoma
... is a subtype of embryonal rhabdomyosarcoma first described by Cavazzana, Schmidt and Ninfo in ... This subtype has a more favorable clinical course and prognosis than usual embryonal rhabdomyosarcoma. Spindle cell ... Cavazzana, A. O.; D. Schmidt; V. Ninfo (1992). "Spindle cell rhabdomyosarcoma: a prognostically favorable variant of ... rhabdomyosarcoma typically occurs in young males and most commonly occurs in paratesticular soft tissue, followed by the head ...
TSPAN31
2004). "Amplification of CDK4, MDM2, SAS and GLI genes in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma". Histol. ...
Alveolar rhabdomyosarcoma
"Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas ... Alveolar rhabdomyosarcoma (ARMS) is a subtype of the rhabdomyosarcoma soft tissue cancer family whose lineage is from ... "Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on ... March 1995). "The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent ...
Fibroblast growth factor receptor 1
2 cases of Embryonal rhabdomyosarcoma, and 2 cases of pleomorphic rhabdomyosarcoma. Rhabdomyosarcoma is a highly malignant form ... The 10 human rhabdomyosarcoma tumor exhibited decreased levels of methylation of CpG islands upstream of the first FGFR1 exon. ... In addition, a single case of rhabdomyosarcoma tumor was found express co-amplified FOXO1 gene at 13q14 and FGFR1 gene at 8p11 ... Elevated expression of FGFR1 protein was detected in 10 of 10 human Rhabdomyosarcoma tumors and 4 of 4 human cell lines derived ...
Splenogonadal fusion
... include visualizing the nonspecific paratesticular masses which can mimic malignancies such as rhabdomyosarcoma or embryonal ...
P53
... a novel small-molecule inhibitor targets MDM2 and induces apoptosis in embryonal and alveolar rhabdomyosarcoma cells with wild- ...
Margaret Ransone Murray
Similar studies were carried out to diagnose neuroblastoma and rhabdomyosarcomas. They were also the first to demonstrate the ... They defined malignant fibrous histiocytoma as a sarcoma composed of tissue histiocytes, which are embryonal forms of ...
Malignant ectomesenchymoma
2003), "Resemblance to embryonal tissue", Holland-Frei Cancer Medicine (6th ed.), Hamilton, Ontario, Canada: BC Decker, ISBN 1- ... MEM is part of a group of small round blue cell tumors which includes neuroblastoma, rhabdomyosarcoma, non-Hodgkin's lymphoma, ... Mesenchymal elements, represented by rhabdomyosarcoma, were the dominant component in the majority of cases (5/6) while ... Translocations in Rhabdomyosarcoma without the Canonical PAX-FOXO1 fuse PAX3 to Members of the Nuclear Receptor Transcriptional ...
Mir-1 microRNA precursor family
Introduction of miR-1 and miR-133a into an embryonal rhabdomyosarcoma-derived cell line is cytostatic, which suggested a strong ... Rhabdomyosarcoma is the most common soft tissue sarcoma in children. Since the tumor results from undifferentiated cells, ... September 2010). "Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells". ... October 2009). "MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development". The Journal of Biological Chemistry. ...
Cancer epigenetics
... alveolar and embryonal) rhabdomyosarcoma. Several oncogenes and tumor suppressor genes are epigenetically altered in sarcomas. ... and rhabdomyosarcoma. Drug targeting and inhibition of EZH2 in Ewing's sarcoma, or of LSD1 in several sarcomas, inhibits tumor ... and rhabdomyosarcoma". Human Pathology. 43 (8): 1300-1307. doi:10.1016/j.humpath.2011.10.010. PMID 22245111. Tam, Kit W.; Zhang ... and expression of the EZH2 component of the PRC2 complex is altered in Ewing's sarcoma and rhabdomyosarcoma. Similarly, ...
PAX3
... embryonal rhabdomyosarcoma). However, PAX3 is also expressed in other cancer types without a clear relationship to a PAX3- ... Alveolar rhabdomyosarcoma (ARMS) is an aggressive soft tissue sarcoma that occurs in children and is usually characterized by a ... Olanich ME, Barr FG (2013). "A call to ARMS: targeting the PAX3-FOXO1 gene in alveolar rhabdomyosarcoma". review. Expert ... Barr FG (September 2001). "Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma". review. Oncogene. ...
Vulvar tumors
... types Adenoma of minor vestibular glands Mixed Tumors of the vulva Tumors of skin appendage origin Embryonal rhabdomyosarcoma ( ...
List of MeSH codes (C04)
... rhabdomyosarcoma, alveolar MeSH C04.557.450.590.550.660.675 - rhabdomyosarcoma, embryonal MeSH C04.557.450.590.775 - sarcoma, ... rhabdomyosarcoma, alveolar MeSH C04.557.450.795.550.660.675 - rhabdomyosarcoma, embryonal MeSH C04.557.450.795.560 - ... embryonal MeSH C04.557.465.220 - chordoma MeSH C04.557.465.280 - dermoid cyst MeSH C04.557.465.330 - germinoma MeSH C04.557. ...
List of diseases (R)
... alveolar Rhabdomyosarcoma, embryonal Rheumatic fever Rheumatism Rheumatoid arthritis Rheumatoid purpura Rheumatoid vasculitis ... Rhabdomyomatous dysplasia cardiopathy genital anomalies Rhabdomyosarcoma Rhabdomyosarcoma 1 Rhabdomyosarcoma 2 Rhabdomyosarcoma ...
Small-blue-round-cell tumor
... the more common fetal and embryonal types do not Merkel cell carcinoma Mesenchymal chondrosarcoma Endometrial stromal ... Desmoplastic small-round-cell tumour Ewing sarcoma/PNET Neuroblastoma Medulloblastoma Rhabdomyosarcoma Synovial sarcoma ...
Beckwith-Wiedemann syndrome
... or umbilical hernia Embryonal tumor (e.g., Wilms tumor, hepatoblastoma, neuroblastoma, rhabdomyosarcoma) in childhood ... rhabdomyosarcoma, and mesoblastic nephroma. Wilms tumor, hepatoblastoma, and mesoblastic nephroma can usually be cured if ...
Hedgehog pathway inhibitor
GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis. Oncotarget. ... including rhabdomyosarcoma, osteosarcoma, neuroblastoma, and ovarian cancer. Arsenic Trioxide (ATO) directly binds to GLI1 and ...
ERMS
... may refer to: Erms, a river of Germany Electronic Resource Management System Embryonal rhabdomyosarcoma Emissions ...
International Classification of Diseases for Oncology
... adult type Pleomorphic rhabdomyosarcoma, NOS M8902/3 Mixed type rhabdomyosarcoma Mixed embryonal rhabdomyosarcoma and alveolar ... NOS Embryonal rhabdomyosarcoma, pleomorphic Sarcoma botryoides Botryoid sarcoma M8912/3 Spindle cell rhabdomyosarcoma M8920/3 ... nonseminomatous M9070/3 Embryonal carcinoma, NOS Embryonal adenocarcinoma M9071/3 Yolk sac tumor Endodermal sinus tumor ... NOS Embryonal teratoma Teratoblastoma, malignant Immature teratoma, malignant or NOS M9081/3 Teratocarcinoma Mixed embryonal ...
Index of oncology articles
... embryonal rhabdomyosarcoma - embryonal tumor - embryonic - EMD 121974 - emitefur - emodin - enalapril - encephalopathy - ... rhabdomyosarcoma - rhizoxin - ribavirin - ribonucleotide reductase inhibitor - rifampin - risedronate - ritonavir - rituximab ...
Sarcoma
Rhabdomyosarcoma is treated with surgery, radiotherapy, or chemotherapy. The majority of rhabdomyosarcoma patients have a 50-85 ... embryonal, alveolar, pleomorphic, and spindle cell/sclerosing) Hemangioendothelioma (includes the following varieties: retiform ... Wexler L (2004). "Rhabdomyosarcoma". ESUN. 1 (4). Retrieved 19 October 2011. Osteosarcoma Treatment & Management~treatment at ... Liposarcoma Treatment & Management~treatment at eMedicine "Rhabdomyosarcoma". Boston Children's Hospital. ...
Intergroup Rhabdomyosarcoma Study Group
... for Newly Diagnosed Patients With Low-Risk Embryonal Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the ... and a separate report in 2011 on improving outcomes for patients with low-risk embryonal rhabdomyosarcoma. The Intergroup ... The Intergroup Rhabdomyosarcoma Study Group (IRS) was a U.S. and Canadian clinical trial cooperative group created with the ... "The Intergroup Rhabdomyosarcoma Study Group (IRSG): Major Lessons From the IRS-I Through IRS-IV Studies as Background for the ...